Effects of low-dose, intermittent treatment with recombinant human parathyroid hormone (1-34) on chondrogenesis in a model of experimental fracture healing

Bone

Volumn 37, Issue 5, 2005, Pages 711-719

  Nakazawa, Tetsuro ^a   Nakajima, Arata ^a   Shiomi, Koji ^b   Moriya, Hideshige ^a   Einhorn, Thomas A ^c   Yamazaki, Masashi ^a  

^a CHIBA UNIVERSITY   (Japan)

^b DAIICHI SANKYO CO   (Japan)

^c BOSTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Chondrogenesis; Fracture healing; Intermittent treatment; Low dose; Parathyroid hormone (PTH)

Indexed keywords

COLLAGEN; OSTEOPONTIN; RECOMBINANT PARATHYROID HORMONE; TRANSCRIPTION FACTOR SOX9;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALLUS; CARTILAGE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CHONDROGENESIS; DOSE RESPONSE; DRUG EFFECT; FEMUR FRACTURE; FRACTURE HEALING; GENE EXPRESSION; MALE; NONHUMAN; RAT; STATISTICAL SIGNIFICANCE; STEM CELL; UPREGULATION;

ANIMALS; BONY CALLUS; CARTILAGE; CELL DIFFERENTIATION; CELL PROLIFERATION; CHONDROGENESIS; COLLAGEN; COLLAGEN TYPE II; DOSE-RESPONSE RELATIONSHIP, DRUG; FRACTURE HEALING; GENE EXPRESSION; GROWTH PLATE; HIGH MOBILITY GROUP PROTEINS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MALE; MESENCHYMAL STEM CELLS; MICE; OSTEOGENESIS; PARATHYROID HORMONE; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; RNA, MESSENGER; TRANSCRIPTION FACTORS;

EID: 26944497581     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2005.06.013     Document Type: Article

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