Sirt7 Contributes to Myocardial Tissue Repair by Maintaining Transforming Growth Factor-β Signaling Pathway

Circulation

Volumn 132, Issue 12, 2015, Pages 1081-1093

  Araki, Satoshi ^a   Izumiya, Yasuhiro ^a   Rokutanda, Taku ^a   Ianni, Alessandro ^c   Hanatani, Shinsuke ^a   Kimura, Yuichi ^a   Onoue, Yoshiro ^a   Senokuchi, Takafumi ^a   Yoshizawa, Tatsuya ^a   Yasuda, Osamu ^c   Koitabashi, Norimichi ^d   Kurabayashi, Masahiko ^d   Braun, Thomas ^b   Bober, Eva ^c   Yamagata, Kazuya ^a   Ogawa, Hisao ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^c KUMAMOTO UNIVERSITY HOSPITAL   (Japan)

^d GUNMA UNIVERSITY   (Japan)

Author keywords

autophagy; fibroblasts; receptors, transforming growth factor beta; sirtuins; wound healing

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; INTERCELLULAR ADHESION MOLECULE 1; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN INTERACTING WITH PROTEIN KINASE C; PROTEIN INTERACTING WITH PROTEIN KINASE C ALPHA; PROTEIN P62; SIRTUIN 7; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; SIRT7 PROTEIN, MOUSE; SIRTUIN; SMALL INTERFERING RNA;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; AUTOPHAGY; CARDIOVASCULAR TISSUE; CELL ADHESION; CELL DIFFERENTIATION; CELL INFILTRATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ECHOCARDIOGRAPHY; HEART FIBROBLAST; HEART HEMODYNAMICS; HEART INFARCTION; HEART MUSCLE; HEART MUSCLE FIBROSIS; HEART RUPTURE; HEMODYNAMIC PARAMETERS; HISTOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; INFLAMMATORY CELL; LIMB ISCHEMIA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TISSUE REPAIR; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; WOUND HEALING; WOUND HEALING IMPAIRMENT; ANIMAL; C57BL MOUSE; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; FIBROBLAST; GENETICS; HEART; HINDLIMB; ISCHEMIA; KNOCKOUT MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REGENERATION; VASCULARIZATION;

ANIMALS; AUTOPHAGY; DISEASE MODELS, ANIMAL; FIBROBLASTS; HEART; HINDLIMB; IN VITRO TECHNIQUES; ISCHEMIA; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIAL INFARCTION; NEOVASCULARIZATION, PHYSIOLOGIC; REGENERATION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SIRTUINS; TRANSFORMING GROWTH FACTOR BETA; WOUND HEALING;

EID: 84942162806     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.114.014821     Document Type: Article

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