SIRT2 knockdown increases basal autophagy and prevents postslippage death by abnormally prolonging the mitotic arrest that is induced by microtubule inhibitors

FEBS Journal

Volumn 281, Issue 11, 2014, Pages 2623-2637

  Inoue, Toshiaki ^a   Nakayama, Yuji ^a   Li, Yanze ^a,b   Matsumori, Haruka ^a   Takahashi, Haruka ^a   Kojima, Hirotada ^c   Wanibuchi, Hideki ^c   Katoh, Motonobu ^a   Oshimura, Mitsuo ^a,b  

^a TOTTORI UNIVERSITY   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

^c OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

autophagy; chemoresistance; microtubule inhibitors; postslippage death; spindle assembly checkpoint

Indexed keywords

SIRTUIN 1; SIRTUIN 2;

ARTICLE; AUTOPHAGY; CELL ACTIVATION; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL DEATH; CELL STRESS; CONTROLLED STUDY; DOWN REGULATION; GENE SILENCING; M PHASE CELL CYCLE CHECKPOINT; MITOSIS INHIBITION; OXIDATIVE STRESS; POSTSLIPPAGE DEATH; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION;

AUTOPHAGY; CHEMORESISTANCE; MICROTUBULE INHIBITORS; POSTSLIPPAGE DEATH; SPINDLE ASSEMBLY CHECKPOINT;

AUTOPHAGY; HCT116 CELLS; HUMANS; MITOSIS; SIRTUIN 1; SIRTUIN 2; SPINDLE APPARATUS; TUBULIN MODULATORS;

EID: 84901822090     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12810     Document Type: Article

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