Mechanical force regulation of myofibroblast differentiation in cardiac fibroblasts

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 285, Issue 5 54-5, 2003, Pages

  Wang, J ^a   Chen, H ^a   Seth, A ^a   McCulloch, C A ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Cell differentiation; Extracellular signal regulated kinase; Force application; Integrins; P38

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALPHA ACTIN; BIOMATERIAL; COLLAGEN; DESMIN; FIBRONECTIN; MAGNETITE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; VIMENTIN;

ACTIN FILAMENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FIBROBLAST; FORCE; HEART; HEART MUSCLE; HEART VENTRICLE OVERLOAD; HEART VENTRICLE PRESSURE; IMMUNOHISTOCHEMISTRY; MATERIAL COATING; MECHANICS; MOUSE; MYOFIBROBLAST; NEWBORN; NONHUMAN; NORTHERN BLOTTING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; SMOOTH MUSCLE; SMOOTH MUSCLE FIBER; STRESS FIBER; TENSILE STRENGTH; WESTERN BLOTTING;

EID: 0142121143     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00387.2003     Document Type: Article

References (47)

1. Arora PD and McCulloch CA. Dependence of collagen remodelling on α-smooth muscle actin expression by fibroblasts. J Cell Physiol 159: 161-175, 1994.
2. Arora PD, Narani N, and McCulloch CA. The compliance of collagen gels regulates transforming growth factor-β induction of α-smooth muscle actin in fibroblasts. Am J Pathol 154: 871-882, 1999.
3. Bershadsky AD, Gluck U, Denisenko ON, Sklyarova TV, Spector I, and Ben-Ze'ev A. The state of actin assembly regulates actin and vinculin expression by a feedback loop. J Cell Sci 108: 1183-1193, 1995.
4. Bouzegrhane F and Thibault G. Is angiotensin II a proliferative factor of cardiac fibroblasts? Cardiovasc Res 53: 304-312, 2002.
5. Burgess ML, Terracio L, Hirozane T, and Borg TK. Differential integrin expression by cardiac fibroblasts from hypertensive and exercise-trained rat hearts. Cardiovasc Pathol 11: 78-87, 2002.
6. Butt RP, Laurent GJ, and Bishop JE. Mechanical load and polypeptide growth factors stimulate cardiac fibroblast activity. Ann NY Acad Sci 752: 387-393, 1995.
7. 1 in cardiac fibroblasts and myofibroblasts. J Mol Cell Cardiol 29: 1947-1958, 1997.
8. Chien KR. Stress pathways and heart failure. Cell 98: 555-558, 1999.
9. 1 integrin-mediated transcriptional circuit that regulates the actin-binding protein filamin-A. J Biol Chem 277: 47541-47550, 2002.
10. Desmouliere A, Badid C, Bochaton-Piallat ML, and Gabbiani G. Apoptosis during wound healing, fibrocontractive diseases and vascular wall injury. Int J Biochem Cell Biol 29: 19-30, 1997.
11. 1 induces α-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J Cell Biol 122: 103-111, 1993.
12. a. Dos Santos, VAPM, Leenen EJTM, Rippoll MM, Van der Sluis C, Van Vliet T, Tramper J, and Wijffels RH. Relevance of rheological properties of gel beads for their mechanical stability in bioreactors. Biotechnol Bioeng 56: 517-529, 1997.
13. Eghbali M. Cardiac fibroblasts: function, regulation of gene expression, and phenotypic modulation. Basic Res Cardiol 87, Suppl 2: 183-189, 1992.
14. 2+ flux in fibroblasts. Am J Physiol Cell Physiol 269: C1093-C1104, 1995.
15. Grove D, Zak R, Nair KG, and Aschenbrenner V. Biochemical correlates of cardiac hypertrophy. IV. Observations on the cellular organization of growth during myocardial hypertrophy in the rat. Circ Res 25: 473-485, 1969.
16. Gurantz D, Cowling RT, Villarreal FJ, and Greenberg BH. Tumor necrosis factor-α upregulates angiotensin II type 1 receptors on cardiac fibroblasts. Circ Res 85: 272-279, 1999.
17. Hinz B, Celetta G, Tomasek JJ, Gabbiani G, and Chaponnier C. α-Smooth muscle actin expression upregulates fibroblast contractile activity. Mol Biol Cell 12: 2730-2741, 2001.
18. 1 integrins and tyrosine kinases. Circ Res 79: 310-316, 1996.
19. Janssen PM and Hunter WC. Force, not sarcomere length, correlates with prolongation of isosarcometric contraction. Am J Physiol Heart Circ Physiol 269: H676-H685, 1995.
20. Jo H, Sipos K, Go YM, Law R, Rong J, and McDonald JM. Differential effect of shear stress on extracellular signal-regulated kinase and N-terminal Jun kinase in endothelial cells. Gi2- and Gbeta/gamma-dependent signaling pathways. J Biol Chem 272: 1395-1401, 1997.
21. Katwa LC, Campbell SE, Tyagi SC, Lee SJ, Cicila GT, and Weber KT. Cultured myofibroblasts generate angiotensin peptides de novo. J Mol Cell Cardiol 29: 1375-1386, 1997.
22. Komuro I, Kudo S, Yamazaki T, Zou Y, Shiojima I, and Yazaki Y. Mechanical stretch activates the stress-activated protein kinases in cardiac myocytes. FASEB J 10: 631-636, 1996.
23. Leslie KO, Taatjes DJ, Schwarz J, vonTurkovich M, and Low RB. Cardiac myofibroblasts express alpha smooth muscle actin during right ventricular pressure overload in the rabbit. Am J Pathol 139: 207-216, 1991.
24. Lew AM, Glogauer M, and Mculloch CA. Specific inhibition of skeletal α-actin gene transcription by applied mechanical forces through integrins and actin. Biochem J 341: 647-653, 1999.
25. MacKenna D, Summerour SR, and Villarreal FJ. Role of mechanical factors in modulating cardiac fibroblast function and extracellular matrix synthesis. Cardiovasc Res 46: 257-263, 2000.
26. 2-terminal kinase activation by mechanical stretch is integrin-dependent and matrix-specific in rat cardiac fibroblasts. J Clin Invest 101: 301-310, 1998.
27. Menard C, Mitchell S, and Spector M. Contractile behavior of smooth muscle actin-containing osteoblasts in collagen-GAG matrices in vitro: implant-related cell contraction. Biomaterials 21: 1867-1877, 2000.
28. Nicoletti A and Michel JB. Cardiac fibrosis and inflammation: interaction with hemodynamic and hormonal factors. Cardiovasc Res 41: 532-543, 1999.
29. Oeckler RA, Kaminski PM, and Wolin MS. Stretch enhances contraction of bovine coronary arteries via an NAD(P)H oxidase-mediated activation of the extracellular signal-regulated kinase mitogen-activated protein kinase cascade. Circ Res 92: 23-31, 2003.
30. Posern G, Sotiropoulos A, and Treisman R. Mutant actins demonstrate a role for unpolymerized actin in control of transcription by serum response factor. Mol Biol Cell 13: 4167-4178, 2002.
31. Ruwhof C and van der Laarse A. Mechanical stress-induced cardiac hypertrophy: mechanisms and signal transduction pathways. Cardiovasc Res 47: 23-37, 2000.
32. Sadoshima J and Izumo S. Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine/paracrine mechanism. EMBO J 12: 1681-1692, 1993.
33. Sadoshima J, Jahn L, Takahashi T, Kulik TJ, and Izumo S. Molecular characterization of the stretch-induced adaptation of cultured cardiac cells. An in vitro model of load-induced cardiac hypertrophy. J Biol Chem 267: 10551-10560, 1992.
34. Sappino AP, Schurch W, and Gabbiani G. Differentiation repertoire of fibroblastic cells: expression of cytoskeletal proteins as marker of phenotypic modulations. Lab Invest 63: 144-161, 1990.
35. Serini G and Gabbiani G. Mechanisms of myofibroblast activity and phenotypic modulation. Exp Cell Res 250: 273-283, 1999.
36. Shivakumar K, Dostal DE, Boheler K, Baker KM, and Lakatta EG. Differential response of cardiac fibroblasts from young adult and senescent rats to ANG II. Am J Physiol Heart Circ Physiol 284: H1454-H1459, 2003.
37. Sun Y, Ramires FJ, Zhou G, Ganjam VK, and Weber KT. Fibrous tissue and angiotensin II. J Mol Cell Cardiol 29: 2001-2012, 1997.
38. Suurmeijer AJ, Clement S, Francesconi A, Bocchi L, Angelini A, Van Veldhuisen DJ, Spagnoli LG, Gabbiani G, and Orlandi A. α-Actin isoform distribution in normal and failing human heart: a morphological, morphometric, and biochemical study. J Pathol 199: 387-397, 2003.
39. Tomasek JJ, Gabbiani G, Hinz B, Chaponnier C, and Brown RA. Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol 3: 349-363, 2002.
40. Van Wamel JE, Ruwhof C, van der Valk-Kokshoorn EJ, Schrier PI, and van der Laarse A. Rapid gene transcription induced by stretch in cardiac myocytes and fibroblasts and their paracrine influence on stationary myocytes and fibroblasts. Pflügers Arch 439: 781-788, 2000.
41. 1 promotes the morphological and functional differentiation of the myofibroblast. Exp Cell Res 257: 180-189, 2000.
42. Wang J, Lukse E, Seth A, and McCulloch CA. Use of conditionally immortalized mouse cardiac fibroblasts to examine the effect of mechanical stretch on α-smooth muscle actin. Tissue Cell 33: 86-96, 2001.
43. Wang J, Seth A, and McCulloch CA. Force regulates smooth muscle actin in cardiac fibroblasts. Am J Physiol Heart Circ Physiol 279: H2776-H2785, 2000.
44. Wang J, Su M, Fan J, Seth A, and McCulloch CA. Transcriptional regulation of a contractile gene by mechanical forces applied through integrins in osteoblasts. J Biol Chem 277: 22889-22895, 2002.
45. Wang Y, Huang S, Sah VP, Ross J Jr, Brown JH, Han J, and Chien KR. Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family. J Biol Chem 273: 2161-2168, 1998.
46. Wilke A, Funck R, Rupp H, and Brilla CG. Effect of the renin-angiotensin-aldosterene system on the cardiac interstitium in heart failure. Basic Res Cardiol 91, Suppl 2: 79-84, 1996.
47. Woodcock-Mitchell J, Mitchell JJ, Low RB, Kieny M, Sengel P, Rubbia L, Skalli O, Jackson B, and Gabbiani G. α-Smooth muscle actin is transiently expressed in embryonic rat cardiac and skeletal muscles. Differentiation 39: 161-166, 1988.