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Volumn 15, Issue 7, 2015, Pages 604-612

Aerosol delivery in the treatment of lung cancer

Author keywords

Aerosol delivery; Chemotherapy; Cytokines; Gene therapy; Lung cancer; Monoclonal antibodies; Toll like receptor agonists

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; AVIDIN; AZACITIDINE; BECLIN 1; CELECOXIB; CETUXIMAB; CISPLATIN; DOCETAXEL; DOXORUBICIN; FLUOROURACIL; GEMCITABINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 2; MACROGOL; OSTEOPONTIN; PACLITAXEL; PROTEIN P53; RUBITECAN; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR AGONIST; AEROSOL; ANTINEOPLASTIC AGENT; DRUG CARRIER;

EID: 84942118597     PISSN: 15680096     EISSN: 18735576     Source Type: Journal    
DOI: 10.2174/1568009615666150602143751     Document Type: Article
Times cited : (20)

References (81)
  • 2
    • 0031015054 scopus 로고    scopus 로고
    • A novel retinoic acid receptor-selective retinoid, ALRT1550, has potent antitumor activity against human oral squamous carcinoma xenografts in nude mice
    • Shalinsky, D.R.; Bischoff, E.D.; Lamph, W.W.; Zhang, L.; Boehm, M.F.; Davies, P.J.A.; Nadzan, A.M.; Heyman, R.A. A novel retinoic acid receptor-selective retinoid, ALRT1550, has potent antitumor activity against human oral squamous carcinoma xenografts in nude mice. Cancer Res., 1997, 57, 162-168.
    • (1997) Cancer Res , vol.57 , pp. 162-168
    • Shalinsky, D.R.1    Bischoff, E.D.2    Lamph, W.W.3    Zhang, L.4    Boehm, M.F.5    Davies, P.J.A.6    Nadzan, A.M.7    Heyman, R.A.8
  • 3
    • 1042291304 scopus 로고    scopus 로고
    • Recent advances in brain tumor therapy: Local intracerebral drug delivery by polymers
    • Guerin, C.; Olivi, A.; Weingart, J.D.; Lawson, H.C.; Brem, H. Recent advances in brain tumor therapy: local intracerebral drug delivery by polymers. Invest New Drugs, 2004, 22, 27-37.
    • (2004) Invest New Drugs , vol.22 , pp. 27-37
    • Guerin, C.1    Olivi, A.2    Weingart, J.D.3    Lawson, H.C.4    Brem, H.5
  • 6
    • 22244439824 scopus 로고    scopus 로고
    • Aerosol gemcitabine inhibits the growth of primary osteosarcoma and osteosarcoma lung metastases
    • Koshkina, N.V. Kleinerman, E.S. Aerosol gemcitabine inhibits the growth of primary osteosarcoma and osteosarcoma lung metastases. Int. J. Cancer, 2005, 116, 458-463.
    • (2005) Int. J. Cancer , vol.116 , pp. 458-463
    • Koshkina, N.V.1    Kleinerman, E.S.2
  • 8
    • 0030982904 scopus 로고    scopus 로고
    • Interleukin-2 liposome inhalation therapy is safe and effective for dogs with spontaneous pulmonary metastases
    • Khanna, C.; Anderson, P.M.; Hasz, D.E.; Katsanis, E.; Neville, M.; Klausner, J.S. Interleukin-2 liposome inhalation therapy is safe and effective for dogs with spontaneous pulmonary metastases. Cancer, 1997, 79, 1409-1421.
    • (1997) Cancer , vol.79 , pp. 1409-1421
    • Khanna, C.1    Anderson, P.M.2    Hasz, D.E.3    Katsanis, E.4    Neville, M.5    Klausner, J.S.6
  • 13
    • 34548094015 scopus 로고    scopus 로고
    • p53 aerosol formulation with low toxicity and high efficiency for early lung cancer treatment
    • Zou, Y.; Tornos, C.; Qiu, X.; Lia, M.; Perez-Soler, R. p53 aerosol formulation with low toxicity and high efficiency for early lung cancer treatment. Clin. Cancer Res., 2007, 13, 4900-4908.
    • (2007) Clin. Cancer Res , vol.13 , pp. 4900-4908
    • Zou, Y.1    Tornos, C.2    Qiu, X.3    Lia, M.4    Perez-Soler, R.5
  • 15
    • 7444262947 scopus 로고    scopus 로고
    • Aerosol delivery of glucosylated polyethylenimine/phosphatase and tensin homologue deleted on chromosome 10 complex suppresses Akt downstream pathways in the lung of K-ras null mice
    • Kim, H.W.; Park, I.K.; Cho, C.S.; Lee, K.H.; Beck, G.R., Jr.; Colburn, N.H.; Cho, M.H. Aerosol delivery of glucosylated polyethylenimine/phosphatase and tensin homologue deleted on chromosome 10 complex suppresses Akt downstream pathways in the lung of K-ras null mice. Cancer Res., 2004, 64, 7971-7976.
    • (2004) Cancer Res , vol.64 , pp. 7971-7976
    • Kim, H.W.1    Park, I.K.2    Cho, C.S.3    Lee, K.H.4    Beck, G.R.5    Colburn, N.H.6    Cho, M.H.7
  • 19
    • 77953766334 scopus 로고    scopus 로고
    • Inhibition of lung tumor growth by complex pulmonary delivery of drugs with oligonucleotides as suppressors of cellular resistance
    • Garbuzenko, O.B.; Saad, M.; Pozharov, V.P.; Reuhl, K.R.; Mainelis, G.; Minko, T. Inhibition of lung tumor growth by complex pulmonary delivery of drugs with oligonucleotides as suppressors of cellular resistance. Proc. Natl Acad. Sci USA., 2010, 107, 10737-10742.
    • (2010) Proc. Natl Acad. Sci USA , vol.107 , pp. 10737-10742
    • Garbuzenko, O.B.1    Saad, M.2    Pozharov, V.P.3    Reuhl, K.R.4    Mainelis, G.5    Minko, T.6
  • 20
    • 0032853556 scopus 로고    scopus 로고
    • Inhalation chemotherapy for macroscopic primary or metastatic lung tumors: Proof of principle using dogs with spontaneously occurring tumors as a model
    • Hershey, A.E.; Kurzman, I.D.; Forrest, L.J.; Bohling, C.A.; Stonerook, M.; Placke, M.E.; Imondi, A.R.; Vail, D.M. Inhalation chemotherapy for macroscopic primary or metastatic lung tumors: proof of principle using dogs with spontaneously occurring tumors as a model. Clin. Cancer Res., 1999, 5, 2653-2659.
    • (1999) Clin. Cancer Res , vol.5 , pp. 2653-2659
    • Hershey, A.E.1    Kurzman, I.D.2    Forrest, L.J.3    Bohling, C.A.4    Stonerook, M.5    Placke, M.E.6    Imondi, A.R.7    Vail, D.M.8
  • 21
    • 0034787791 scopus 로고    scopus 로고
    • Paclitaxel liposome aerosol treatment induces inhibition of pulmonary metastases in murine renal carcinoma model
    • Koshkina, N.V.; Waldrep, J.C.; Roberts, L.E.; Golunski, E.; Melton, S.; Knight, V. Paclitaxel liposome aerosol treatment induces inhibition of pulmonary metastases in murine renal carcinoma model. Clin. Cancer Res., 2001, 7, 3258-3262.
    • (2001) Clin. Cancer Res , vol.7 , pp. 3258-3262
    • Koshkina, N.V.1    Waldrep, J.C.2    Roberts, L.E.3    Golunski, E.4    Melton, S.5    Knight, V.6
  • 26
    • 43949144185 scopus 로고    scopus 로고
    • Pulmonary gemcitabine delivery for treating lung cancer: Pharmacokinetics and acute lung injury aspects in animals
    • Min, R.; Li, T.; Du, J.; Zhang, Y.; Guo, J.; Lu, W.L. Pulmonary gemcitabine delivery for treating lung cancer: pharmacokinetics and acute lung injury aspects in animals. Can. J. Physiol. Pharmacol., 2008, 86, 288-298.
    • (2008) Can. J. Physiol. Pharmacol , vol.86 , pp. 288-298
    • Min, R.1    Li, T.2    Du, J.3    Zhang, Y.4    Guo, J.5    Lu, W.L.6
  • 29
    • 84876492723 scopus 로고    scopus 로고
    • Efficacy of aerosolized celecoxib encapsulated nanostructured lipid carrier in non-small cell lung cancer in combination with docetaxel
    • Patel, A.R.; Chougule, M.B.; Patlolla, R.; Wang, G.; Singh, M. Efficacy of aerosolized celecoxib encapsulated nanostructured lipid carrier in non-small cell lung cancer in combination with docetaxel. Pharm. Res., 2013, 30, 1435-1446.
    • (2013) Pharm. Res , vol.30 , pp. 1435-1446
    • Patel, A.R.1    Chougule, M.B.2    Patlolla, R.3    Wang, G.4    Singh, M.5
  • 30
    • 0027421114 scopus 로고
    • Further study of nebulisation chemotherapy, a new chemotherapeutic method in the treatment of lung carcinomas: Fundamental and clinical
    • Tatsumura, T.; Koyama, S.; Tsujimoto, M.; Kitagawa, M.; Kagamimori, S. Further study of nebulisation chemotherapy, a new chemotherapeutic method in the treatment of lung carcinomas: fundamental and clinical. Br. J. Cancer, 1993, 68, 1146-1149.
    • (1993) Br. J. Cancer , vol.68 , pp. 1146-1149
    • Tatsumura, T.1    Koyama, S.2    Tsujimoto, M.3    Kitagawa, M.4    Kagamimori, S.5
  • 31
    • 1842479077 scopus 로고    scopus 로고
    • Clinical evaluation of the delivery and safety of aerosolized liposomal 9-nitro-20(s)-camptothecin in patients with advanced pulmonary malignancies
    • Verschraegen, C.F.; Gilbert, B.E.; Loyer, E.; Huaringa, A.; Walsh, G.; Newman, R.A.; Knight, V. Clinical evaluation of the delivery and safety of aerosolized liposomal 9-nitro-20(s)-camptothecin in patients with advanced pulmonary malignancies. Clin. Cancer Res., 2004, 10, 2319-2326.
    • (2004) Clin. Cancer Res , vol.10 , pp. 2319-2326
    • Verschraegen, C.F.1    Gilbert, B.E.2    Loyer, E.3    Huaringa, A.4    Walsh, G.5    Newman, R.A.6    Knight, V.7
  • 36
    • 84908309405 scopus 로고    scopus 로고
    • Mechanism of action of immunotherapy
    • Epub;%2014 Sep 6., S3-13
    • Disis, M.L. Mechanism of action of immunotherapy. Semin. Oncol. 2014, 41 Suppl 5:S3-13. doi: 10.1053/j.seminoncol.2014.09.004. Epub;%2014 Sep 6., S3-13.
    • (2014) Semin. Oncol , vol.41 , pp. S3-13
    • Disis, M.L.1
  • 38
    • 0025753704 scopus 로고
    • The IL-2 mediated amplification of cellular cytotoxicity
    • Grimm, E.A. Owen-Schaub, L. The IL-2 mediated amplification of cellular cytotoxicity. J. Cell. Biochem., 1991, 45, 335-339.
    • (1991) J. Cell. Biochem , vol.45 , pp. 335-339
    • Grimm, E.A.1    Owen-Schaub, L.2
  • 39
    • 50949131519 scopus 로고    scopus 로고
    • Interleukin-12 improves cytotoxicity of natural killer cells vi upregulated expression of NKG2D
    • Zhang, C.; Zhang, J.; Niu, J.; Zhou, Z.; Zhang, J.; Tian, Z. Interleukin-12 improves cytotoxicity of natural killer cells vi upregulated expression of NKG2D. Hum. Immunol., 2008, 69, 490-500.
    • (2008) Hum. Immunol , vol.69 , pp. 490-500
    • Zhang, C.1    Zhang, J.2    Niu, J.3    Zhou, Z.4    Zhang, J.5    Tian, Z.6
  • 40
    • 0032535052 scopus 로고    scopus 로고
    • Emerging applications of recombinant human granulocyte-macrophage colony-stimulating factor
    • Armitage, J.O. Emerging applications of recombinant human granulocyte-macrophage colony-stimulating factor. Blood, 1998, 92, 4491-4508.
    • (1998) Blood , vol.92 , pp. 4491-4508
    • Armitage, J.O.1
  • 41
    • 0026515571 scopus 로고
    • Interleukin-2 by inhalation: Local therapy for metastatic renal cell carcinoma
    • Huland, E.; Huland, H.; Heinzer, H. Interleukin-2 by inhalation: local therapy for metastatic renal cell carcinoma. J. Urol., 1992, 147, 344-348.
    • (1992) J. Urol , vol.147 , pp. 344-348
    • Huland, E.1    Huland, H.2    Heinzer, H.3
  • 42
    • 0027979468 scopus 로고
    • Inhaled interleukin-2 in combination with low-dose systemic interleukin-2 and interferon alpha in patients with pulmonary metastatic renal-cell carcinoma: Effectiveness and toxicity of mainly local treatment
    • Huland, E.; Heinzer, H.; Huland, H. Inhaled interleukin-2 in combination with low-dose systemic interleukin-2 and interferon alpha in patients with pulmonary metastatic renal-cell carcinoma: effectiveness and toxicity of mainly local treatment. J. Cancer Res., Clin, Oncol., 1994, 120, 221-228.
    • (1994) J. Cancer Res., Clin, Oncol , vol.120 , pp. 221-228
    • Huland, E.1    Heinzer, H.2    Huland, H.3
  • 44
    • 0032703878 scopus 로고    scopus 로고
    • Subjective and objective prospective, long-term analysis of quality of life during inhaled interleukin-2 immunotherapy
    • Heinzer, H.; Mir, T.S.; Huland, E.; Huland, H. Subjective and objective prospective, long-term analysis of quality of life during inhaled interleukin-2 immunotherapy. J. Clin. Oncol., 1999, 17, 3612-3620.
    • (1999) J. Clin. Oncol , vol.17 , pp. 3612-3620
    • Heinzer, H.1    Mir, T.S.2    Huland, E.3    Huland, H.4
  • 46
    • 33846699695 scopus 로고    scopus 로고
    • Retrospective review in patients with pulmonary metastases of renal cell carcinoma receiving inhaled recombinant interleukin-2
    • Esteban-Gonzalez, E.; Carballido, J.; Navas, V.; Torregrosa, Z.; Munoz, A.; de Mon, M.A. Retrospective review in patients with pulmonary metastases of renal cell carcinoma receiving inhaled recombinant interleukin-2. Anticancer Drugs, 2007, 18, 291-296.
    • (2007) Anticancer Drugs , vol.18 , pp. 291-296
    • Esteban-Gonzalez, E.1    Carballido, J.2    Navas, V.3    Torregrosa, Z.4    Munoz, A.5    de Mon, M.A.6
  • 48
    • 0027538181 scopus 로고
    • Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
    • Dranoff, G.; Jaffee, E.; Lazenby, A.; Golumbek, P.; Levitsky, H.; Brose, K.; Jackson, V.; Hamada, H.; Pardoll, D.; Mulligan, R.C. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc. Natl. Acad. Sci. USA., 1993, 90, 3539-3543.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3539-3543
    • Dranoff, G.1    Jaffee, E.2    Lazenby, A.3    Golumbek, P.4    Levitsky, H.5    Brose, K.6    Jackson, V.7    Hamada, H.8    Pardoll, D.9    Mulligan, R.C.10
  • 49
    • 0141926517 scopus 로고    scopus 로고
    • Aerosolized granulocyte macrophage colony-stimulating factor (GM-CSF) therapy in metastatic cancer
    • Rao, R.D.; Anderson, P.M.; Arndt, C.A.; Wettstein, P.J.; Markovic, S.N. Aerosolized granulocyte macrophage colony-stimulating factor (GM-CSF) therapy in metastatic cancer. Am. J. Clin. Oncol., 2003, 26, 493-498.
    • (2003) Am. J. Clin. Oncol , vol.26 , pp. 493-498
    • Rao, R.D.1    Anderson, P.M.2    Arndt, C.A.3    Wettstein, P.J.4    Markovic, S.N.5
  • 50
    • 33748683549 scopus 로고    scopus 로고
    • Oligodeoxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma
    • Link, B.K.; Ballas, Z.K.; Weisdorf, D.; Wooldridge, J.E.; Bossler, A.D.; Shannon, M.; Rasmussen, W.L.; Krieg, A.M.; Weiner, G.J. Oligodeoxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma. J. Immunother., 2006, 29, 558-568.
    • (2006) J. Immunother , vol.29 , pp. 558-568
    • Link, B.K.1    Ballas, Z.K.2    Weisdorf, D.3    Wooldridge, J.E.4    Bossler, A.D.5    Shannon, M.6    Rasmussen, W.L.7    Krieg, A.M.8    Weiner, G.J.9
  • 51
    • 37849002321 scopus 로고    scopus 로고
    • Toll-like receptor 9 (TLR9) agonists in the treatment of cancer
    • Krieg, A.M. Toll-like receptor 9 (TLR9) agonists in the treatment of cancer. Oncogene, 2008, 27, 161-167.
    • (2008) Oncogene , vol.27 , pp. 161-167
    • Krieg, A.M.1
  • 52
    • 55249083982 scopus 로고    scopus 로고
    • Phase 1 evaluation of intralesionally injected TLR9-agonist PF-3512676 in patients with basal cell carcinoma or metastatic melanoma
    • Hofmann, M.A.; Kors, C.; Audring, H.; Walden, P.; Sterry, W.; Trefzer, U. Phase 1 evaluation of intralesionally injected TLR9-agonist PF-3512676 in patients with basal cell carcinoma or metastatic melanoma. J. Immunother., 2008, 31, 520-527.
    • (2008) J. Immunother , vol.31 , pp. 520-527
    • Hofmann, M.A.1    Kors, C.2    Audring, H.3    Walden, P.4    Sterry, W.5    Trefzer, U.6
  • 55
    • 77949512384 scopus 로고    scopus 로고
    • Route of administration of the TLR9 agonist CpG critically determines the efficacy of cancer immunotherapy in mice
    • Nierkens, S.; den Brok, M.H.; Roelofsen, T.; Wagenaars, J.A.; Figdor, C.G.; Ruers, T.J.; Adema, G.J. Route of administration of the TLR9 agonist CpG critically determines the efficacy of cancer immunotherapy in mice. PLoS ONE, 2009, 4, 8368.
    • (2009) PLoS ONE , vol.4 , pp. 8368
    • Nierkens, S.1    den Brok, M.H.2    Roelofsen, T.3    Wagenaars, J.A.4    Figdor, C.G.5    Ruers, T.J.6    Adema, G.J.7
  • 56
  • 58
    • 77957339234 scopus 로고    scopus 로고
    • Antitumor effect of inhalatory lipopolysaccharide and synergetic effect in combination with cyclophosphamide
    • Hirota, K.; Oishi, Y.; Taniguchi, H.; Sawachi, K.; Inagawa, H.; Kohchi, C.; Soma, G.; Terada, H. Antitumor effect of inhalatory lipopolysaccharide and synergetic effect in combination with cyclophosphamide. Anticancer Res., 2010, 30, 3129-3134.
    • (2010) Anticancer Res , vol.30 , pp. 3129-3134
    • Hirota, K.1    Oishi, Y.2    Taniguchi, H.3    Sawachi, K.4    Inagawa, H.5    Kohchi, C.6    Soma, G.7    Terada, H.8
  • 59
    • 84881286933 scopus 로고    scopus 로고
    • Inhaled gene therapy in lung cancer: Proof-of-concept for nano-oncology and nanobiotechnology in the management of lung cancer
    • Zarogoulidis, P.; Darwiche, K.; Hohenforst-Schmidt, W.; Huang, H.; Li, Q.; Freitag, L.; Zarogoulidis, K. Inhaled gene therapy in lung cancer: proof-of-concept for nano-oncology and nanobiotechnology in the management of lung cancer. Future Oncol., 2013, 9, 1171-1194.
    • (2013) Future Oncol , vol.9 , pp. 1171-1194
    • Zarogoulidis, P.1    Darwiche, K.2    Hohenforst-Schmidt, W.3    Huang, H.4    Li, Q.5    Freitag, L.6    Zarogoulidis, K.7
  • 60
    • 0035114195 scopus 로고    scopus 로고
    • Pulmonary cytokine responses associated with PEI-DNA aerosol gene therapy
    • Gautam, A.; Densmore, C.L.; Waldrep, J.C. Pulmonary cytokine responses associated with PEI-DNA aerosol gene therapy. Gene. Ther., 2001, 8, 254-257.
    • (2001) Gene. Ther , vol.8 , pp. 254-257
    • Gautam, A.1    Densmore, C.L.2    Waldrep, J.C.3
  • 61
    • 0034294818 scopus 로고    scopus 로고
    • Inhibition of experimental lung metastasis by aerosol delivery of PEI-p53 complexes
    • Gautam, A.; Densmore, C.L.; Waldrep, J.C. Inhibition of experimental lung metastasis by aerosol delivery of PEI-p53 complexes. Mol Ther., 2000, 2, 318-323.
    • (2000) Mol Ther , vol.2 , pp. 318-323
    • Gautam, A.1    Densmore, C.L.2    Waldrep, J.C.3
  • 64
    • 84879421764 scopus 로고    scopus 로고
    • Aerosol delivery of eukaryotic translation initiation factor 4Ebinding protein 1 effectively suppresses lung tumorigenesis in KrasLA1 mice
    • Chang, S.H.; Kim, J.E.; Lee, J.H.; Minai-Tehrani, A.; Han, K.; Chae, C.; Cho, Y.H.; Yun, J.H.; Park, K.; Kim, Y.S.; Cho, M.H. Aerosol delivery of eukaryotic translation initiation factor 4Ebinding protein 1 effectively suppresses lung tumorigenesis in KrasLA1 mice. Cancer Gene Ther., 2013, 20, 331-335.
    • (2013) Cancer Gene Ther , vol.20 , pp. 331-335
    • Chang, S.H.1    Kim, J.E.2    Lee, J.H.3    Minai-Tehrani, A.4    Han, K.5    Chae, C.6    Cho, Y.H.7    Yun, J.H.8    Park, K.9    Kim, Y.S.10    Cho, M.H.11
  • 66
    • 0036203989 scopus 로고    scopus 로고
    • Growth inhibition of established B16-F10 lung metastases by sequential aerosol delivery of p53 gene and 9-nitrocamptothecin
    • Gautam, A.; Waldrep, J.C.; Densmore, C.L.; Koshkina, N.; Melton, S.; Roberts, L.; Gilbert, B.; Knight, V. Growth inhibition of established B16-F10 lung metastases by sequential aerosol delivery of p53 gene and 9-nitrocamptothecin. Gene Ther., 2002, 9, 353-357.
    • (2002) Gene Ther , vol.9 , pp. 353-357
    • Gautam, A.1    Waldrep, J.C.2    Densmore, C.L.3    Koshkina, N.4    Melton, S.5    Roberts, L.6    Gilbert, B.7    Knight, V.8
  • 68
    • 36249017868 scopus 로고    scopus 로고
    • Nanoparticles for drug delivery to the lungs
    • Sung, J.C.; Pulliam, B.L.; Edwards, D.A. Nanoparticles for drug delivery to the lungs. Trends Biotechnol., 2007, 25, 563-570.
    • (2007) Trends Biotechnol , vol.25 , pp. 563-570
    • Sung, J.C.1    Pulliam, B.L.2    Edwards, D.A.3
  • 69
    • 0036407029 scopus 로고    scopus 로고
    • Bioengineering of therapeutic aerosols
    • Edwards, D.A. Dunbar, C. Bioengineering of therapeutic aerosols. Annu. Rev. Biomed. Eng., 2002, 4, 93-107.
    • (2002) Annu. Rev. Biomed. Eng , vol.4 , pp. 93-107
    • Edwards, D.A.1    Dunbar, C.2
  • 70
    • 33845906339 scopus 로고    scopus 로고
    • Inhaling medicines: Delivering drugs to the body through the lungs
    • Patton, J.S. Byron, P.R. Inhaling medicines: delivering drugs to the body through the lungs. Nat. Rev. Drug Discov., 2007, 6, 67-74.
    • (2007) Nat. Rev. Drug Discov , vol.6 , pp. 67-74
    • Patton, J.S.1    Byron, P.R.2
  • 72
    • 84879470777 scopus 로고    scopus 로고
    • Characterization and aerosol dispersion performance of advanced spray-dried chemotherapeutic PEGylated phospholipid particles for dry powder inhalation delivery in lung cancer
    • Meenach, S.A.; Anderson, K.W.; Zach, H.J.; McGarry, R.C.; Mansour, H.M. Characterization and aerosol dispersion performance of advanced spray-dried chemotherapeutic PEGylated phospholipid particles for dry powder inhalation delivery in lung cancer. Eur. J. Pharm. Sci., 2013, 49, 699-711.
    • (2013) Eur. J. Pharm. Sci , vol.49 , pp. 699-711
    • Meenach, S.A.1    Anderson, K.W.2    Zach, H.J.3    McGarry, R.C.4    Mansour, H.M.5
  • 73
    • 84893096818 scopus 로고    scopus 로고
    • Encapsulation into PEG-liposomes does not improve the bioavailability of pulmonary delivered salmon calcitonin
    • Swaminathan, J.; Gobbo, O.L.; Tewes, F.; Healy, A.M.; Ehrhardt, C. Encapsulation into PEG-liposomes does not improve the bioavailability of pulmonary delivered salmon calcitonin. J. Aerosol. Med. Pulm. Drug Deliv., 2014, 27, 1-11.
    • (2014) J. Aerosol. Med. Pulm. Drug Deliv , vol.27 , pp. 1-11
    • Swaminathan, J.1    Gobbo, O.L.2    Tewes, F.3    Healy, A.M.4    Ehrhardt, C.5
  • 74
    • 84921038571 scopus 로고    scopus 로고
    • Nanomedicine in cancer therapy: Challenges, opportunities, and clinical applications
    • Wicki, A.; Witzigmann, D.; Balasubramanian, V.; Huwyler, J. Nanomedicine in cancer therapy: challenges, opportunities, and clinical applications. J. Control. Release, 2015, 200, 138-157.
    • (2015) J. Control. Release , vol.200 , pp. 138-157
    • Wicki, A.1    Witzigmann, D.2    Balasubramanian, V.3    Huwyler, J.4
  • 75
    • 42649137232 scopus 로고    scopus 로고
    • Targeted delivery of nanoparticles for the treatment of lung diseases
    • Azarmi, S.; Roa, W.H.; Lobenberg, R. Targeted delivery of nanoparticles for the treatment of lung diseases. Adv. Drug Deliv. Rev., 2008, 60, 863-875.
    • (2008) Adv. Drug Deliv. Rev , vol.60 , pp. 863-875
    • Azarmi, S.1    Roa, W.H.2    Lobenberg, R.3
  • 77
    • 84910619872 scopus 로고    scopus 로고
    • A novel potential biocompatible hyperbranched polyspermine for efficient lung cancer gene therapy
    • Xie, R.L.; Jang, Y.J.; Xing, L.; Zhang, B.F.; Wang, F.Z.; Cui, P.F.; Cho, M.H.; Jiang, H.L. A novel potential biocompatible hyperbranched polyspermine for efficient lung cancer gene therapy. Int. J. Pharm., 2014, 478, 19-30.
    • (2014) Int. J. Pharm , vol.478 , pp. 19-30
    • Xie, R.L.1    Jang, Y.J.2    Xing, L.3    Zhang, B.F.4    Wang, F.Z.5    Cui, P.F.6    Cho, M.H.7    Jiang, H.L.8
  • 78
    • 81255143432 scopus 로고    scopus 로고
    • Innovative strategy for treatment of lung cancer: Targeted nanotechnologybased inhalation co-delivery of anticancer drugs and siRNA
    • Taratula, O.; Garbuzenko, O.B.; Chen, A.M.; Minko, T. Innovative strategy for treatment of lung cancer: targeted nanotechnologybased inhalation co-delivery of anticancer drugs and siRNA. J. Drug Target, 2011, 19, 900-914.
    • (2011) J. Drug Target , vol.19 , pp. 900-914
    • Taratula, O.1    Garbuzenko, O.B.2    Chen, A.M.3    Minko, T.4
  • 79
    • 84901808611 scopus 로고    scopus 로고
    • Poly(amidoamine) dendrimer nanocarriers and their aerosol formulations for siRNA delivery to the lung epithelium
    • Conti, D.S.; Brewer, D.; Grashik, J.; Avasarala, S.; da, R., Sr. Poly(amidoamine) dendrimer nanocarriers and their aerosol formulations for siRNA delivery to the lung epithelium. Mol. Pharm., 2014, 11, 1808-1822.
    • (2014) Mol. Pharm , vol.11 , pp. 1808-1822
    • Conti, D.S.1    Brewer, D.2    Grashik, J.3    Avasarala, S.4    Da, R.5


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