A novel retinoic acid receptor-selective retinoid, ALRT1550, has potent antitumor activity against human oral squamous carcinoma xenografts in nude mice

Cancer Research

Volumn 57, Issue 1, 1997, Pages 162-168

  Shalinsky, David R ^a,c   Bischoff, Eric D ^a   Lamph, William W ^a   Zhang, Lin ^a   Boehm, Marcus F ^a   Davies, Peter J A ^b   Nadzan, Alex M ^a   Heyman, Richard A ^a  

^a LIGAND PHARMACEUTICALS INC   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c AGOURON PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [2 [5,6 DIHYDRO 5,5 DIMETHYL 8 (4 METHYLPHENYL) 2 NAPHTHYL]ETHYNYL]BENZOIC ACID; 7 (3,5 DI TERT BUTYLPHENYL) 3 METHYL 2,4,6 OCTATRIENOIC ACID; 7 (3,5 DI TERT BUTYLPHENYL) 3 METHYLOCTA 2,4,6 TRIENOIC ACID; ALITRETINOIN; RECEPTOR BLOCKING AGENT; RETINOIC ACID RECEPTOR; RETINOID; RETINOID X RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CARCINOMA CELL; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; DRUG RECEPTOR BINDING; FEMALE; HUMAN; HUMAN CELL; INTRAGASTRIC DRUG ADMINISTRATION; MOUSE; MOUTH CARCINOMA; NONHUMAN; NUDE MOUSE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RETINOL INTOXICATION; SQUAMOUS CELL CARCINOMA; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MICE; MICE, NUDE; MOUTH NEOPLASMS; RECEPTORS, RETINOIC ACID; RETINOIDS; TRANSPLANTATION, HETEROLOGOUS;

EID: 0031015054     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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