메뉴 건너뛰기




Volumn 162, Issue , 2015, Pages 14-19

In vitro evaluation of dual agonists for PPARγ/β from the flower of Edgeworthia gardneri (wall.) Meisn

Author keywords

Diabetes mellitus; Dual agonists; Edgeworthia gardneri (Wall.) Meisn; Ethyl acetate extract; PPAR

Indexed keywords

4 [4 [3 (4 ACETYL 3 HYDROXY 2 PROPYLPHENOXY)PROPOXY]PHENOXY]ACETIC ACID; ACETIC ACID ETHYL ESTER; BUTANOL; EDGEWORTHIA GARDNERI EXTRACT; HEXANE; PENTADECANOIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PLANT EXTRACT; ROSIGLITAZONE; UMBELLIFERONE; UNCLASSIFIED DRUG; 7-HYDROXYCOUMARIN; FATTY ACID; UMBELLIFERONE DERIVATIVE;

EID: 84942105330     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.12.034     Document Type: Article
Times cited : (25)

References (39)
  • 6
  • 7
    • 79960988152 scopus 로고    scopus 로고
    • Effects of the new dual PPAR alpha/delta agonist GFT505 on lipid and glucose homeostasis in abdominally obese patients with combined dyslipidemia or impaired glucose metabolism
    • B. Cariou, Y. Zair, B. Staels, and E. Bruckert Effects of the new dual PPAR alpha/delta agonist GFT505 on lipid and glucose homeostasis in abdominally obese patients with combined dyslipidemia or impaired glucose metabolism Diabetes Care 34 2011 2008 2014
    • (2011) Diabetes Care , vol.34 , pp. 2008-2014
    • Cariou, B.1    Zair, Y.2    Staels, B.3    Bruckert, E.4
  • 8
    • 77952997178 scopus 로고    scopus 로고
    • Control of macrophage activation and function by PPARs
    • A. Chawla Control of macrophage activation and function by PPARs Circulation Research 106 2010 1559 1569
    • (2010) Circulation Research , vol.106 , pp. 1559-1569
    • Chawla, A.1
  • 11
    • 84942089920 scopus 로고    scopus 로고
    • α-Glucosidase inhibitory activity of the alabastrum of Edgeworthia gardneri (Wall.) Meisn
    • Y. Geng, H.M. Yang, H.Y. Xu, and J.S. Shi α-Glucosidase inhibitory activity of the alabastrum of Edgeworthia gardneri (Wall.) Meisn Journal of Food Science and Biotechnology 32 2013 967 971
    • (2013) Journal of Food Science and Biotechnology , vol.32 , pp. 967-971
    • Geng, Y.1    Yang, H.M.2    Xu, H.Y.3    Shi, J.S.4
  • 13
    • 84893794489 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and their ligands: Nutritional and clinical implications-A review
    • B. Grygiel-Gorniak Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications-a review Nutrition Journal 13 2014 17
    • (2014) Nutrition Journal , vol.13 , pp. 17
    • Grygiel-Gorniak, B.1
  • 16
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • I. Issemann, and S. Green Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators Nature 347 1990 645 650
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 17
    • 79952002653 scopus 로고    scopus 로고
    • Review: Effects of PPAR activation in the placenta and the fetus: Implications in maternal diabetes
    • A. Jawerbaum, and E. Capobianco Review: effects of PPAR activation in the placenta and the fetus: implications in maternal diabetes Placenta 32 2011 S212 S217
    • (2011) Placenta , vol.32 , pp. S212-S217
    • Jawerbaum, A.1    Capobianco, E.2
  • 20
    • 12944319825 scopus 로고    scopus 로고
    • Thiazolidinediones improve insulin sensitivity in adipose tissue and reduce the hyperlipidaemia without affecting the hyperglycaemia in a transgenic model of type 2 diabetes
    • H. Kim, M. Haluzik, O. Gavrilova, S. Yakar, J. Portas, H. Sun, U.B. Pajvani, P.E. Scherer, and D. LeRoith Thiazolidinediones improve insulin sensitivity in adipose tissue and reduce the hyperlipidaemia without affecting the hyperglycaemia in a transgenic model of type 2 diabetes Diabetologia 47 2004 2215 2225
    • (2004) Diabetologia , vol.47 , pp. 2215-2225
    • Kim, H.1    Haluzik, M.2    Gavrilova, O.3    Yakar, S.4    Portas, J.5    Sun, H.6    Pajvani, U.B.7    Scherer, P.E.8    LeRoith, D.9
  • 25
    • 0037900979 scopus 로고    scopus 로고
    • Minireview: Lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors
    • C.H. Lee, P. Olson, and R.M. Evans Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors Endocrinology 144 2003 2201 2207
    • (2003) Endocrinology , vol.144 , pp. 2201-2207
    • Lee, C.H.1    Olson, P.2    Evans, R.M.3
  • 27
    • 84862004194 scopus 로고    scopus 로고
    • Design novel dual agonists for treating type-2 diabetes by targeting peroxisome proliferator-activated receptors with core hopping approach
    • Y. Ma, S.Q. Wang, W.R. Xu, R.L. Wang, and K.C. Chou Design novel dual agonists for treating type-2 diabetes by targeting peroxisome proliferator-activated receptors with core hopping approach PLoS One 7 2012 e38546
    • (2012) PLoS One , vol.7 , pp. e38546
    • Ma, Y.1    Wang, S.Q.2    Xu, W.R.3    Wang, R.L.4    Chou, K.C.5
  • 28
    • 84889092515 scopus 로고    scopus 로고
    • Harnessing the benefits of PPARbeta/delta agonists
    • L.S. Mackenzie, and L. Lione Harnessing the benefits of PPARbeta/delta agonists Life Sciences 93 2013 963 967
    • (2013) Life Sciences , vol.93 , pp. 963-967
    • MacKenzie, L.S.1    Lione, L.2
  • 29
    • 84865507796 scopus 로고    scopus 로고
    • Lipid effects of peroxisome proliferator-activated receptor-delta agonist GW501516 in subjects with low high-density lipoprotein cholesterol: Characteristics of metabolic syndrome
    • E.J. Olson, G.L. Pearce, N.P. Jones, and D.L. Sprecher Lipid effects of peroxisome proliferator-activated receptor-delta agonist GW501516 in subjects with low high-density lipoprotein cholesterol: characteristics of metabolic syndrome Arteriosclerosis, Thrombosis, and Vascular Biology 32 2012 2289 2294
    • (2012) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.32 , pp. 2289-2294
    • Olson, E.J.1    Pearce, G.L.2    Jones, N.P.3    Sprecher, D.L.4
  • 30
    • 80053521381 scopus 로고    scopus 로고
    • Mechanism of action of a peroxisome proliferator-activated receptor (PPAR)-delta agonist on lipoprotein metabolism in dyslipidemic subjects with central obesity
    • E.M. Ooi, G.F. Watts, D.L. Sprecher, D.C. Chan, and P.H. Barrett Mechanism of action of a peroxisome proliferator-activated receptor (PPAR)-delta agonist on lipoprotein metabolism in dyslipidemic subjects with central obesity The Journal of Clinical Endocrinology and Metabolism 96 2011 E1568 1576
    • (2011) The Journal of Clinical Endocrinology and Metabolism , vol.96 , pp. E1568-1576
    • Ooi, E.M.1    Watts, G.F.2    Sprecher, D.L.3    Chan, D.C.4    Barrett, P.H.5
  • 32
    • 84887210784 scopus 로고    scopus 로고
    • Refocusing peroxisome proliferator activated receptor-alpha: A new insight for therapeutic roles in diabetes
    • H. Seok, and B.S. Cha Refocusing peroxisome proliferator activated receptor-alpha: a new insight for therapeutic roles in diabetes Diabetes & Metabolism Journal 37 2013 326 332
    • (2013) Diabetes & Metabolism Journal , vol.37 , pp. 326-332
    • Seok, H.1    Cha, B.S.2
  • 33
    • 79958244231 scopus 로고    scopus 로고
    • PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation
    • T. Varga, Z. Czimmerer, and L. Nagy PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation Biochimica et Biophysica Acta 1812 2011 1007 1022
    • (2011) Biochimica et Biophysica Acta 1812 , pp. 1007-1022
    • Varga, T.1    Czimmerer, Z.2    Nagy, L.3
  • 34
    • 85014780454 scopus 로고    scopus 로고
    • The dual PPAR-alpha/gamma agonist aleglitazar increases number and function of endothelial progenitor cells: Implications for vascular function and atherogenesis
    • C. Werner, C. Gensch, V. Pavlickova, J. Poess, M. Wright, M. Boehm, and U. Laufs The dual PPAR-alpha/gamma agonist aleglitazar increases number and function of endothelial progenitor cells: implications for vascular function and atherogenesis European Heart Journal 34 2013 P2390
    • (2013) European Heart Journal , vol.34 , pp. P2390
    • Werner, C.1    Gensch, C.2    Pavlickova, V.3    Poess, J.4    Wright, M.5    Boehm, M.6    Laufs, U.7
  • 35
    • 84878159522 scopus 로고    scopus 로고
    • Development of a cell-based high-throughput peroxisome proliferator-activated receptors (PPARs) screening model and its application for evaluation of the extracts from Rhizoma Coptis
    • Z.N. Xia, Y.X. Lin, L.X. Guo, F.Q. Yang, P. Xu, Y.L. Zhang, and J.H. Liu Development of a cell-based high-throughput peroxisome proliferator-activated receptors (PPARs) screening model and its application for evaluation of the extracts from Rhizoma Coptis Journal of Asian Natural Products Research 15 2013 225 234
    • (2013) Journal of Asian Natural Products Research , vol.15 , pp. 225-234
    • Xia, Z.N.1    Lin, Y.X.2    Guo, L.X.3    Yang, F.Q.4    Xu, P.5    Zhang, Y.L.6    Liu, J.H.7
  • 36
    • 84865048500 scopus 로고    scopus 로고
    • Chemical constituents from Edgeworthia gardneri (Thymelaeaceae)
    • P. Xu, Z. Xia, and Y. Lin Chemical constituents from Edgeworthia gardneri (Thymelaeaceae) Biochemical Systematics and Ecology 45 2012 148 150
    • (2012) Biochemical Systematics and Ecology , vol.45 , pp. 148-150
    • Xu, P.1    Xia, Z.2    Lin, Y.3
  • 38
    • 84955496519 scopus 로고    scopus 로고
    • The preparation methods and application on diabetic nephropathy of the extracts of Edgeworthia gardneri (Wall.) Meisn
    • 201110128975
    • G.Y. Zhong, P. Xu, Y.X. Lin, X.M. Liang, and F.Q. Yang The preparation methods and application on diabetic nephropathy of the extracts of Edgeworthia gardneri (Wall.) Meisn China Patent 201110128975 2011 9
    • (2011) China Patent , pp. 9
    • Zhong, G.Y.1    Xu, P.2    Lin, Y.X.3    Liang, X.M.4    Yang, F.Q.5
  • 39
    • 78649516943 scopus 로고    scopus 로고
    • Daphnodorin dimers from Edgeworthia chrysantha with α-glucosidase inhibitory activity
    • T. Zhou, S.W. Zhang, S.S. Liu, H.J. Cong, and L.J. Xuan Daphnodorin dimers from Edgeworthia chrysantha with α-glucosidase inhibitory activity Phytochemistry Letters 3 2010 242 247
    • (2010) Phytochemistry Letters , vol.3 , pp. 242-247
    • Zhou, T.1    Zhang, S.W.2    Liu, S.S.3    Cong, H.J.4    Xuan, L.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.