Structurally diverse genes encode Tlr2 in rainbow trout: The conserved receptor cannot be stimulated by classical ligands to activate NF-κB in vitro

Developmental and Comparative Immunology

Volumn 54, Issue 1, 2016, Pages 75-88

  Brietzke, Andreas ^a   Arnemo, Marianne ^b   Gjøen, Tor ^b   Rebl, Henrike ^c   Korytář, Tomáš ^d,e   Goldammer, Tom ^a   Rebl, Alexander ^a   Seyfert, Hans Martin ^a  

^a LEIBNIZ INSTITUTE FOR FARM ANIMAL BIOLOGY FBN   (Germany)

^b UNIVERSITY OF OSLO   (Norway)

^c ROSTOCK UNIVERSITY MEDICAL CENTER   (Germany)

^d FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

^e UNIVERSITY OF PENNSYLVANIA SCHOOL OF VETERINARY MEDICINE   (United States)

Author keywords

Innate immunity; Pattern recognition receptors; Salmonid; Teleost; TLR2

Indexed keywords

COMPLEMENTARY DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIGAND; LIPOPEPTIDE; MYELOID DIFFERENTIATION FACTOR 88; SYNTHETIC PEPTIDE; TOLL LIKE RECEPTOR 2;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL LINE; CHSE 214 CELL; CONTROLLED STUDY; DIMERIZATION; DNA SEQUENCE; EXON; GENE EXPRESSION; GENETIC VARIABILITY; HEK293 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIGAND BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCORHYNCHUS MYKISS; PHYLOGENETIC TREE; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SALMONINE; SIGNAL TRANSDUCTION; TISSUE LEVEL; TLR2 GENE; TRANSCRIPTION INITIATION; ANIMAL; CONFOCAL MICROSCOPY; CONSERVED SEQUENCE; FLOW CYTOMETRY; GENETIC POLYMORPHISM; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; IMMUNOPRECIPITATION; METABOLISM; MOLECULAR GENETICS; PHYLOGENY; POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CONSERVED SEQUENCE; FLOW CYTOMETRY; HEK293 CELLS; HUMANS; IMMUNOPRECIPITATION; LIGANDS; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; NF-KAPPA B; ONCORHYNCHUS MYKISS; PHYLOGENY; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; SEQUENCE ALIGNMENT; TOLL-LIKE RECEPTOR 2; TRANSFECTION;

EID: 84942023609     PISSN: 0145305X     EISSN: 18790089     Source Type: Journal    
DOI: 10.1016/j.dci.2015.08.012     Document Type: Article

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