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Volumn 29, Issue 18, 2015, Pages 1955-1968

MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links

Author keywords

BRCA2; DNA2; Interstrand cross link repair; MERIT40; Ubiquitination

Indexed keywords

BRCA2 PROTEIN; FANCONI ANEMIA GROUP D2 PROTEIN; MERIT40 PROTEIN; MESSENGER RNA; MITOMYCIN; PROTEIN; RAP80 PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; BRCA2 PROTEIN, MOUSE; CELL CYCLE PROTEIN; DNA HELICASE; FANCD2 PROTEIN, MOUSE; MERIT40 PROTEIN, MOUSE; RAP80 PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TRANSCRIPTION FACTOR;

EID: 84941956000     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.264192.115     Document Type: Article
Times cited : (22)

References (69)
  • 1
    • 84857781943 scopus 로고    scopus 로고
    • A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response
    • Adamson B, Smogorzewska A, Sigoillot FD, King RW, Elledge SJ. 2012. A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response. Nat Cell Biol 14: 318-328.
    • (2012) Nat Cell Biol , vol.14 , pp. 318-328
    • Adamson, B.1    Smogorzewska, A.2    Sigoillot, F.D.3    King, R.W.4    Elledge, S.J.5
  • 7
    • 84885024085 scopus 로고    scopus 로고
    • Advances in understanding the complex mechanisms of DNA interstrand crosslink repair
    • Clauson C, Scharer OD, Niedernhofer L. 2013. Advances in understanding the complex mechanisms of DNA interstrand crosslink repair. Cold Spring Harb Perspect Med 5: a012732.
    • (2013) Cold Spring Harb Perspect Med , vol.5
    • Clauson, C.1    Scharer, O.D.2    Niedernhofer, L.3
  • 8
    • 79953869356 scopus 로고    scopus 로고
    • The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection
    • Coleman KA, Greenberg RA. 2011. The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection. J Biol Chem 286: 13669-13680.
    • (2011) J Biol Chem , vol.286 , pp. 13669-13680
    • Coleman, K.A.1    Greenberg, R.A.2
  • 9
    • 62649104153 scopus 로고    scopus 로고
    • K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1
    • Cooper EM, Cutcliffe C, Kristiansen TZ, Pandey A, Pickart CM, Cohen RE. 2009. K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1. EMBO J 28: 621-631.
    • (2009) EMBO J , vol.28 , pp. 621-631
    • Cooper, E.M.1    Cutcliffe, C.2    Kristiansen, T.Z.3    Pandey, A.4    Pickart, C.M.5    Cohen, R.E.6
  • 11
  • 12
    • 79959635260 scopus 로고    scopus 로고
    • DNA interstrand crosslink repair and cancer
    • Deans AJ, West SC. 2011. DNA interstrand crosslink repair and cancer. Nat Rev Cancer 11: 467-480.
    • (2011) Nat Rev Cancer , vol.11 , pp. 467-480
    • Deans, A.J.1    West, S.C.2
  • 14
    • 63049083118 scopus 로고    scopus 로고
    • MERIT40 facilitates BRCA1 localization and DNA damage repair
    • Feng L, Huang J, Chen J. 2009. MERIT40 facilitates BRCA1 localization and DNA damage repair. Genes Dev 23: 719-728.
    • (2009) Genes Dev , vol.23 , pp. 719-728
    • Feng, L.1    Huang, J.2    Chen, J.3
  • 15
    • 77957260099 scopus 로고    scopus 로고
    • The Lys63-specific deubiquitinating enzyme BRCC36 is regulated by two scaffold proteins localizing in different subcellular compartments
    • Feng L, Wang J, Chen J. 2010. The Lys63-specific deubiquitinating enzyme BRCC36 is regulated by two scaffold proteins localizing in different subcellular compartments. J Biol Chem 285: 30982-30988.
    • (2010) J Biol Chem , vol.285 , pp. 30982-30988
    • Feng, L.1    Wang, J.2    Chen, J.3
  • 16
    • 84894412116 scopus 로고    scopus 로고
    • Why does the bone marrow fail in Fanconi anemia?
    • Garaycoechea JI, Patel KJ. 2014. Why does the bone marrow fail in Fanconi anemia? Blood 123: 26-34.
    • (2014) Blood , vol.123 , pp. 26-34
    • Garaycoechea, J.I.1    Patel, K.J.2
  • 18
    • 84941969036 scopus 로고    scopus 로고
    • Repair versus checkpoint functions of BRCA1 are differentially regulated by site of chromatin binding
    • Goldstein M, Kastan MB. 2015. Repair versus checkpoint functions of BRCA1 are differentially regulated by site of chromatin binding. Cancer Res 75: 2699-2707.
    • (2015) Cancer Res , vol.75 , pp. 2699-2707
    • Goldstein, M.1    Kastan, M.B.2
  • 20
    • 84870760201 scopus 로고    scopus 로고
    • RNF4-dependent hybrid SUMO-ubiquitin chains are signals for RAP80 and thereby mediate the recruitment of BRCA1 to sites of DNA damage
    • Guzzo CM, Berndsen CE, Zhu J, Gupta V, Datta A, Greenberg RA, Wolberger C, Matunis MJ. 2012. RNF4-dependent hybrid SUMO-ubiquitin chains are signals for RAP80 and thereby mediate the recruitment of BRCA1 to sites of DNA damage. Sci Signal 5: 88.
    • (2012) Sci Signal , vol.5 , pp. 88
    • Guzzo, C.M.1    Berndsen, C.E.2    Zhu, J.3    Gupta, V.4    Datta, A.5    Greenberg, R.A.6    Wolberger, C.7    Matunis, M.J.8
  • 21
    • 0032994839 scopus 로고    scopus 로고
    • Measurement of DNA crosslinking in patients on ifosfamide therapy using the single cell gel electrophoresis (Comet) assay
    • Hartley JM, Spanswick VJ, Gander M, Giacomini G, Whelan J, Souhami RL, Hartley JA. 1999. Measurement of DNA crosslinking in patients on ifosfamide therapy using the single cell gel electrophoresis (comet) assay. Clin Cancer Res 5: 507-512.
    • (1999) Clin Cancer Res , vol.5 , pp. 507-512
    • Hartley, J.M.1    Spanswick, V.J.2    Gander, M.3    Giacomini, G.4    Whelan, J.5    Souhami, R.L.6    Hartley, J.A.7
  • 22
    • 79954528832 scopus 로고    scopus 로고
    • RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci
    • Hu Y, Scully R, Sobhian B, Xie A, Shestakova E, Livingston DM. 2011. RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci. Genes Dev 25: 685-700.
    • (2011) Genes Dev , vol.25 , pp. 685-700
    • Hu, Y.1    Scully, R.2    Sobhian, B.3    Xie, A.4    Shestakova, E.5    Livingston, D.M.6
  • 25
    • 75149189204 scopus 로고    scopus 로고
    • BRCA1 and its toolbox for the maintenance of genome integrity
    • Huen MSY, Sy SMH, Chen J. 2009. BRCA1 and its toolbox for the maintenance of genome integrity. Nat Rev Mol Cell Biol 11: 138-148.
    • (2009) Nat Rev Mol Cell Biol , vol.11 , pp. 138-148
    • Huen, M.1    Sy, S.2    Chen, J.3
  • 26
    • 84876886904 scopus 로고    scopus 로고
    • Regulation of DNA damage responses by ubiquitin and SUMO
    • Jackson SP, Durocher D. 2013. Regulation of DNA damage responses by ubiquitin and SUMO. Mol Cel 49: 795-807.
    • (2013) Mol Cel , vol.49 , pp. 795-807
    • Jackson, S.P.1    Durocher, D.2
  • 27
    • 0032559794 scopus 로고    scopus 로고
    • Replicon clusters are stable units of chromosome structure: Evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells
    • Jackson DA, Pombo A. 1998. Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells. J Cell Biol 140: 1285-1295.
    • (1998) J Cell Biol , vol.140 , pp. 1285-1295
    • Jackson, D.A.1    Pombo, A.2
  • 28
    • 84937509603 scopus 로고    scopus 로고
    • Deciphering the BRCA1 tumor suppressor network
    • Jiang Q, Greenberg RA. 2015. Deciphering the BRCA1 tumor suppressor network. J Biol Chem 290: 17724-17732.
    • (2015) J Biol Chem , vol.290 , pp. 17724-17732
    • Jiang, Q.1    Greenberg, R.A.2
  • 29
    • 84900559537 scopus 로고    scopus 로고
    • Preventing over-resection by DNA2 helicase/nuclease suppresses repair defects in Fanconi anemia cells
    • Karanja KK, Lee EH, Hendrickson EA, Campbell JL. 2014. Preventing over-resection by DNA2 helicase/nuclease suppresses repair defects in Fanconi anemia cells. Cell Cycle 13: 1540-1550.
    • (2014) Cell Cycle , vol.13 , pp. 1540-1550
    • Karanja, K.K.1    Lee, E.H.2    Hendrickson, E.A.3    Campbell, J.L.4
  • 30
    • 84863670930 scopus 로고    scopus 로고
    • Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway
    • Kim H, D’Andrea AD. 2012. Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway. Genes Dev 26: 1393-1408.
    • (2012) Genes Dev , vol.26 , pp. 1393-1408
    • Kim, H.1    D’andrea, A.D.2
  • 31
    • 34249950879 scopus 로고    scopus 로고
    • Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response
    • Kim H, Yu X. 2007. Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response. Science 316: 1202-1205.
    • (2007) Science , vol.316 , pp. 1202-1205
    • Kim, H.1    Yu, X.2
  • 33
    • 84872578210 scopus 로고    scopus 로고
    • Fanconi anaemia and the repair of Watson and Crick DNA crosslinks
    • Kottemann MC, Smogorzewska A. 2013. Fanconi anaemia and the repair of Watson and Crick DNA crosslinks. Nature 493: 356-363.
    • (2013) Nature , vol.493 , pp. 356-363
    • Kottemann, M.C.1    Smogorzewska, A.2
  • 35
    • 84877823968 scopus 로고    scopus 로고
    • Function of BRCA1 in the DNA damage response is mediated by ADP-ribosylation
    • Li M, Yu X. 2013. Function of BRCA1 in the DNA damage response is mediated by ADP-ribosylation. Cancer Cell 23: 693-704.
    • (2013) Cancer Cell , vol.23 , pp. 693-704
    • Li, M.1    Yu, X.2
  • 36
    • 84920996478 scopus 로고    scopus 로고
    • BRCA1 promotes unloading of theCMGhelicase from a stalledDNAreplication fork
    • Long DT, Joukov V, Budzowska M, Walter JC. 2014. BRCA1 promotes unloading of theCMGhelicase from a stalledDNAreplication fork. Mol Cel 56: 174-185.
    • (2014) Mol Cel , vol.56 , pp. 174-185
    • Long, D.T.1    Joukov, V.2    Budzowska, M.3    Walter, J.C.4
  • 39
    • 75549087964 scopus 로고    scopus 로고
    • The ubiquitin landscape at DNA double-strand breaks
    • Messick TE, Greenberg RA. 2009. The ubiquitin landscape at DNA double-strand breaks. J Cell Biol 187: 319-326.
    • (2009) J Cell Biol , vol.187 , pp. 319-326
    • Messick, T.E.1    Greenberg, R.A.2
  • 41
    • 84926226900 scopus 로고    scopus 로고
    • Replication fork reversal in eukaryotes: From dead end to dynamic response
    • Neelsen KJ, Lopes M. 2015. Replication fork reversal in eukaryotes: from dead end to dynamic response. Nat Rev Mol Cell Biol 16: 207-220.
    • (2015) Nat Rev Mol Cell Biol , vol.16 , pp. 207-220
    • Neelsen, K.J.1    Lopes, M.2
  • 43
    • 77957284673 scopus 로고    scopus 로고
    • Differential regulation of JAMM domain deubiquitinating enzyme activity within the RAP80 complex
    • Patterson-Fortin J, Shao G, Bretscher H, Messick TE, Greenberg RA. 2010. Differential regulation of JAMM domain deubiquitinating enzyme activity within the RAP80 complex. J Biol Chem 285: 30971-30981.
    • (2010) J Biol Chem , vol.285 , pp. 30971-30981
    • Patterson-Fortin, J.1    Shao, G.2    Bretscher, H.3    Messick, T.E.4    Greenberg, R.A.5
  • 44
    • 76849109722 scopus 로고    scopus 로고
    • Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair
    • Petermann E, Orta ML, Issaeva N, Schultz N, Helleday T. 2010. Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair. Mol Cel 37: 492-502.
    • (2010) Mol Cel , vol.37 , pp. 492-502
    • Petermann, E.1    Orta, M.L.2    Issaeva, N.3    Schultz, N.4    Helleday, T.5
  • 46
    • 84937454590 scopus 로고    scopus 로고
    • MERIT40 deficiency expands hematopoietic stem cell pools by regulating thrombopoietin receptor signaling
    • Rozenova K, Jiang J, Donaghy R, Aressy B, Greenberg RA, Tong W. 2015. MERIT40 deficiency expands hematopoietic stem cell pools by regulating thrombopoietin receptor signaling. Blood 125: 1730-1738.
    • (2015) Blood , vol.125 , pp. 1730-1738
    • Rozenova, K.1    Jiang, J.2    Donaghy, R.3    Aressy, B.4    Greenberg, R.A.5    Tong, W.6
  • 47
    • 72449162040 scopus 로고    scopus 로고
    • Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by NZF domains of TAB2 and TAB3
    • Sato Y, Yoshikawa A, Yamashita M, Yamagata A, Fukai S. 2009. Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by NZF domains of TAB2 and TAB3. EMBOJ 28: 3903-3909.
    • (2009) EMBOJ , vol.28 , pp. 3903-3909
    • Sato, Y.1    Yoshikawa, A.2    Yamashita, M.3    Yamagata, A.4    Fukai, S.5
  • 49
    • 79955799175 scopus 로고    scopus 로고
    • Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11
    • Schlacher K, Christ N, Siaud N, Egashira A, Wu H, Jasin M. 2011. Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11. Cell 145: 529-542.
    • (2011) Cell , vol.145 , pp. 529-542
    • Schlacher, K.1    Christ, N.2    Siaud, N.3    Egashira, A.4    Wu, H.5    Jasin, M.6
  • 50
    • 84863753191 scopus 로고    scopus 로고
    • A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2
    • Schlacher K, Wu H, Jasin M. 2012. A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2. Cancer Cell 22: 106-116.
    • (2012) Cancer Cell , vol.22 , pp. 106-116
    • Schlacher, K.1    Wu, H.2    Jasin, M.3
  • 55
    • 0034888424 scopus 로고    scopus 로고
    • Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity
    • Silver DP, Livingston DM. 2001. Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity. Mol Cel 8: 233-243.
    • (2001) Mol Cel , vol.8 , pp. 233-243
    • Silver, D.P.1    Livingston, D.M.2
  • 56
    • 62549161305 scopus 로고    scopus 로고
    • Linkage-specific avidity defines the lysine 63-linked polyubiquitin-binding preference of Rap80
    • Sims JJ, Cohen RE. 2009. Linkage-specific avidity defines the lysine 63-linked polyubiquitin-binding preference of Rap80. Mol Cel 33: 775-783.
    • (2009) Mol Cel , vol.33 , pp. 775-783
    • Sims, J.J.1    Cohen, R.E.2
  • 60
    • 0000957605 scopus 로고    scopus 로고
    • Measurement of drug-induced DNAinterstrand crosslinking using the single-cell gel electrophoresis (Comet) assay
    • Spanswick VJ, Hartley JM, Ward TH, Hartley JA. 1999. Measurement of drug-induced DNAinterstrand crosslinking using the single-cell gel electrophoresis (comet) assay. Methods Mol Med 28: 143-154.
    • (1999) Methods Mol Med , vol.28 , pp. 143-154
    • Spanswick, V.J.1    Hartley, J.M.2    Ward, T.H.3    Hartley, J.A.4
  • 65
    • 63049138322 scopus 로고    scopus 로고
    • NBA1, a new player in the Brca1 A complex, is required forDNAdamage resistance and checkpoint control
    • Wang B, Hurov K, Hofmann K, Elledge SJ. 2009. NBA1, a new player in the Brca1 A complex, is required forDNAdamage resistance and checkpoint control. Genes Dev 23: 729-739.
    • (2009) Genes Dev , vol.23 , pp. 729-739
    • Wang, B.1    Hurov, K.2    Hofmann, K.3    Elledge, S.J.4
  • 66
    • 84863315246 scopus 로고    scopus 로고
    • RAP80 protein is important for genomic stability and is required for stabilizing BRCA1-A complex at DNA damage sites in vivo
    • Wu J, Liu C, Chen J, Yu X. 2012. RAP80 protein is important for genomic stability and is required for stabilizing BRCA1-A complex at DNA damage sites in vivo. J Biol Chem 287: 22919-22926.
    • (2012) J Biol Chem , vol.287 , pp. 22919-22926
    • Wu, J.1    Liu, C.2    Chen, J.3    Yu, X.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.