Enhanced antitumor effect of shikonin by inhibiting Endoplasmic Reticulum Stress via JNK/c-Jun pathway in human glioblastoma stem cells

Biochemical and Biophysical Research Communications

Volumn 466, Issue 1, 2015, Pages 103-110

  Liu, Jing ^a   Wang, Ping ^a   Xue, Yi Xue ^a   Li, Zhen ^a   Qu, Cheng Bin ^a   Liu, Yun Hui ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Endoplasmic Reticulum Stress; Glioblastoma stem cells; JNK c Jun pathway; Shikonin; Unfolded protein response

Indexed keywords

4 PHENYLBUTYRIC ACID; PROTEIN C JUN; SHIKONIN; ANTINEOPLASTIC AGENT; HERBACEOUS AGENT; NAPHTHOQUINONE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; GLIOBLASTOMA; HUMAN; HUMAN CELL; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; UNFOLDED PROTEIN RESPONSE; ANIMAL; CANCER STEM CELL; CELL CULTURE; DRUG EFFECTS; METABOLISM; NUDE MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELLS, CULTURED; DRUGS, CHINESE HERBAL; ENDOPLASMIC RETICULUM STRESS; GLIOBLASTOMA; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MAP KINASE SIGNALING SYSTEM; MICE, NUDE; NAPHTHOQUINONES; NEOPLASTIC STEM CELLS;

EID: 84941936190     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.08.115     Document Type: Article

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