RETRACTED ARTICLE:The apoptotic effect of shikonin on human papillary thyroid carcinoma cells through mitochondrial pathway

Tumor Biology

Volumn 35, Issue 3, 2014, Pages 1791-1798

  Liu, Chibo ^a   Yin, Lihui ^b   Chen, Jiayu ^d,e   Chen, Jiaqi ^c  

^a TAIZHOU MUNICIPAL HOSPITAL   (China)

^b BLOOD RESEARCH INSTITUTE   (United States)

^c JILIN UNIVERSITY   (China)

^d WENZHOU MEDICAL UNIVERSITY   (China)

^e TAIZHOU UNIVERSITY   (China)

Author keywords

Cell apoptosis; Mitochondria signal pathway; Papillary thyroid cancer; Shikonin

Indexed keywords

CASPASE 3; PROTEIN BAX; PROTEIN BCL 2; SHIKONIN;

APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL CYCLE; CELL CYCLE ARREST; CELL NUCLEUS; CELL PROLIFERATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; THYROID CARCINOMA;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; CARCINOMA; CELL LINE, TUMOR; CELL PROLIFERATION; FLOW CYTOMETRY; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; NAPHTHOQUINONES; REAL-TIME POLYMERASE CHAIN REACTION; THYROID NEOPLASMS;

EID: 84898871543     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-013-1238-5     Document Type: TB

References (19)

1. Aschebrook-Kilfoy B, Ward MH, Sabra MM, Devesa SS. Thyroid cancer incidence patterns in the United States by histologic type, 1992-2006. Thyroid. 2011;21(2):125-34.
2. Han W, Xie J, Fang Y, Wang Z, Pan H. Nec-1 enhances shikonin-induced apoptosis in leukemia cells by inhibition of RIP-1 and ERK1/2. Int J Mol Sci. 2012;13(6):7212-25.
3. Gong K, Li W. Shikonin, a Chinese plant-derived naphthoquinone, induces apoptosis in hepatocellular carcinoma cells through reactive oxygen species: a potential new treatment for hepatocellular carcinoma. Free Radic Biol Med. 2011;51(12):2259-71.
4. Sasi N, Hwang M, Jaboin J, Csiki I, Lu B. Regulated cell death pathways: new twists in modulation of Bcl-2 family function [J]. Mol Cancer Ther. 2009;8(6):1421-9.
5. Hsu P, Huang Y, Tsai M, Wang YJ, Lin JK, Pan MH. Induction of apoptosis by shikonin through coordinative modulation of the Bcl-2 family, p27, and p53, release of cytochrome c and sequential activation of caspases in human colorectal carcinoma cells. J Agric Food Chem. 2004;52(20):6330-7.
6. Salvioli S, Ardizzoni A, Franceschi C, Cossarizza A. JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis. FEBS Lett. 1997;411(1):77-82.
7. Kretschmer N, Rinner B, Deutsch AJ, Lohberger B, Knausz H, Kunert O, et al. Naphthoquinones from Onosma paniculata induce cell-cycle arrest and apoptosis in melanoma cells. J Nat Prod. 2012;75(5):865-9.
8. Chang IC, Huang YJ, Chiang TI, Yeh CW, Hsu LS. Shikonin induces apoptosis through reactive oxygen species/extracellular signal-regulated kinase pathway in osteosarcoma cells. Biol Pharm Bull. 2010;33(5):816-24.
9. Fan Y, Jin S, He J, Shao Z, Yan J, Feng T, et al. Effect of β,β-dimethylacrylshikonin on inhibition of human colorectal cancer cell growth in vitro and in vivo. Int J Mol Sci. 2012;13(7):9184-93.
10. Elumalai P, Gunadharini DN, Senthilkumar K, Banudevi S, Arunkumar R, Benson CS, et al. Induction of apoptosis in human breast cancer cells by nimbolide through extrinsic and intrinsic pathway. Toxicol Lett. 2012;215(2):131-42.
11. Lu L, Qin A, Huang H, Zhou P, Zhang C, Liu N, et al. Shikonin extracted from medicinal Chinese herbs exerts anti-inflammatory effect via proteasome inhibition. Eur J Pharmacol. 2011;658(2-3):242-7.
12. Leibowitz B, Yu J. Mitochondrial signaling in cell death via the Bcl-2 family. Cancer Biol Ther. 2010;9(6):417-22.
13. Abe H, Yoshizaki F. In vitro antifungal activity of naphthoquinone derivatives. Biol Pharm Bull. 2002;25(5):669-70.
14. Gao H, Liu L, Qu ZY, Wei FX, Wang SQ, Chen G, et al. Anti-adenovirus activities of shikonin, a component of Chinese herbal medicine in vitro. Biol Pharm Bull. 2011;34(2):197-202.
15. Andújar I, Ríos JL, Giner RM, Recio MC. Shikonin promotes intestinal wound healing in vitro via induction of TGF-β release in IEC-18 cells. Eur J Pharm Sci. 2013;49(4):637-41.
16. Kontogiannopoulos KN, Assimopoulou AN, Hatziantoniou S, Karatasos K, Demetzos C, Papageorgiou VP. Chimeric advanced drug delivery nano systems (chi-aDDnSs) for shikonin combining dendritic and liposomal technology. Int J Phann. 2012;422(1-2):381-9.
17. Yin SY, Peng AP, Huang LT, Wang YT, Lan CW, Yang NS. The phytochemical shikonin stimulates epithelial-mesenchymal transition (EMT) in skin wound healing. Evid Based Complement Alternat Med. 2013;2013:262796.
18. Sankawa U, Ebizuka Y, Miyazaki T, Isomura Y, Otsuka H. Antitumor activity of shikonin and its derivatives. Chem Pharm Bull (Tokyo). 1977;25(9):2392-5.
19. Sankawa U, Otsuka H, Kataoka Y, Iitaka Y, Hoshi A, Kuretani K. Antitumor activity of shikonin, alkannin and their derivatives. II. X-ray analysis of cyclo-alkannin leucoacetate, tautomerism of alkannin and cyclo-alkannin and antitumor activity of alkannin derivatives. Chem Pharm Bull (Tokyo). 1981;29(1):116-2.