Topoisomerase I inhibitors, shikonin and topotecan, inhibit growth and induce apoptosis of glioma cells and glioma stem cells

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Zhang, Feng Lei ^a   Wang, Ping ^a   Liu, Yun Hui ^a   Liu, Li Bo ^a   Liu, Xiao Bai ^a   Li, Zhen ^a   Xue, Yi Xue ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; DNA TOPOISOMERASE INHIBITOR; PROTEIN BCL 2; SHIKONIN; TOPOTECAN;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL COUNTING; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL VIABILITY; DOWN REGULATION; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVATION; FLOW CYTOMETER; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IC 50; PROTEIN EXPRESSION; TUMOR RECURRENCE;

APOPTOSIS; BRAIN NEOPLASMS; CASPASE 3; CASPASE 9; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GLIOMA; HUMANS; NAPHTHOQUINONES; NEOPLASTIC STEM CELLS; PROTO-ONCOGENE PROTEINS C-BCL-2; TOPOISOMERASE I INHIBITORS; TOPOTECAN;

EID: 84896738574     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081815     Document Type: Article

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