Shikonin suppresses tumor growth and synergizes with gemcitabine in a pancreatic cancer xenograft model: Involvement of NF-κB signaling pathway

Biochemical Pharmacology

Volumn 88, Issue 3, 2014, Pages 322-333

  Wang, Yongwei ^a   Zhou, Yinan ^a   Jia, Guang ^a   Han, Bing ^a   Liu, Ji ^a   Teng, Yueqiu ^a   Lv, Jiachen ^a   Song, Zengfu ^a   Li, Yilong ^a   Ji, Liang ^a   Pan, Shangha ^a   Jiang, Hongchi ^a   Sun, Bei ^a  

^a THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Gemcitabine; NF B; Pancreatic Cancer; Shikonin

Indexed keywords

CASPASE 3; CASPASE 9; GEMCITABINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KI 67 ANTIGEN; SHIKONIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CANCER SIZE; CAPILLARY DENSITY; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG POTENTIATION; DRUG STRUCTURE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MOUSE; NICK END LABELING; NONHUMAN; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

GEMCITABINE; NF-ΚB; PANCREATIC CANCER; SHIKONIN;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL SURVIVAL; DEOXYCYTIDINE; DRUG SYNERGISM; HUMANS; MALE; MICE; MICE, NUDE; MICROVESSELS; NAPHTHOQUINONES; NEOVASCULARIZATION, PATHOLOGIC; NF-KAPPA B; PANCREATIC NEOPLASMS; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84897112795     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2014.01.041     Document Type: Article

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