Constitutive activation of myosin-dependent contractility sensitizes glioma tumor-initiating cells to mechanical inputs and reduces tissue invasion

Cancer Research

Volumn 75, Issue 6, 2015, Pages 1113-1122

  Wong, Sophie Y ^a,b   Ulrich, Theresa A ^a,b,e   Deleyrolle, Loic P ^c   MacKay, Joanna L ^a,f   Lin, Jung Ming G ^a,b   Martuscello, Regina T ^c   Jundi, Musa A ^c   Reynolds, Brent A ^c,d   Kumar, Sanjay ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b University of California   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF QUEENSLAND   (Australia)

^e Massachusetts Institute of Technology   (United States)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LAMININ; MYOSIN; MYOSIN LIGHT CHAIN KINASE; NESTIN; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INFILTRATION; CARCINOGENESIS; CELL FUNCTION; CELL MIGRATION; CELL MOTILITY; CELL POPULATION; CELL PROLIFERATION; CELL SHAPE; CELL SPREADING; CONTRACTION STRESS; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; FEMALE; GLIOBLASTOMA; GLIOBLASTOMA CELL LINE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MECHANOTRANSDUCTION; MOUSE; NONHUMAN; PHENOTYPE; PREDICTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; RIGIDITY; SIGNAL TRANSDUCTION; SURVIVAL TIME; TUMOR CELL; TUMOR INITIATING CELL; TUMOR INVASION; XENOTRANSPLANTATION; ANIMAL; BRAIN TUMOR; CANCER STEM CELL; CELL MOTION; GLIOMA; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ANIMALS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; EXTRACELLULAR MATRIX; FEMALE; GLIOMA; HUMANS; MICE; MYOSINS; NEOPLASM INVASIVENESS; NEOPLASTIC STEM CELLS; RHOA GTP-BINDING PROTEIN;

EID: 84941661809     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-3426     Document Type: Article

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