2-Amino-9H-pyrido[2,3-b]indole (AαC) adducts and thiol oxidation of serum albumin as potential biomarkers of tobacco smoke

Journal of Biological Chemistry

Volumn 290, Issue 26, 2015, Pages 16304-16318

  Pathak, Khyatiben V ^a   Bellamri, Medjda ^b   Wang, Yi ^a   Langouët, Sophie ^b   Turesky, Robert J ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITÉ DE RENNES 1   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; BODY FLUIDS; METABOLITES; MOLECULAR BIOLOGY; OXIDATION; POLYCYCLIC AROMATIC HYDROCARBONS; PROTEINS; SULFUR COMPOUNDS; TOBACCO;

ADDUCT FORMATION; GENOTOXIC METABOLITES; HETEROCYCLIC AROMATIC AMINES; HUMAN HEPATOCYTES; HUMAN SERUM ALBUMINS; PYRIDO[2 ,3-B]; REACTIVE OXYGEN SPECIES; THIOL OXIDATION;

SMOKE;

2 AMINO 9H PYRIDO[2,3 B]INDOLE; ALBUMIN; INDOLE DERIVATIVE; N (DEOXYGUANOSIN 8 YL) 2 AMINO 9H PYRIDO[2,3 B]INDOLE; N ACETYLOXY 2 AMINO 9H PYRIDO[2,3 B]INDOLE; REACTIVE OXYGEN METABOLITE; SULFENAMIDE DERIVATIVE; SULFINAMIDE; SULFONAMIDE; THIOL; TOBACCO SMOKE; UNCLASSIFIED DRUG; 2-AMINO-9H-PYRIDO(2,3-B)INDOLE; BIOLOGICAL MARKER; CARBOLINE DERIVATIVE; DNA ADDUCT; SERUM ALBUMIN; SMOKE; THIOL DERIVATIVE;

ALBUMIN BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIVER CELL; MASS SPECTROMETRY; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEOMICS; ADVERSE EFFECTS; CHEMISTRY; DNA ADDUCT; GENETICS; METABOLISM; OXIDATION REDUCTION REACTION; PROTEIN MOTIF; SMOKE; TOBACCO;

AMINO ACID MOTIFS; BIOMARKERS; CARBOLINES; DNA ADDUCTS; HEPATOCYTES; HUMANS; OXIDATION-REDUCTION; SERUM ALBUMIN; SMOKE; SULFHYDRYL COMPOUNDS; TOBACCO;

EID: 84941312519     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.646539     Document Type: Article

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