Honeybush herbal teas (Cyclopia spp.) contribute to high levels of dietary exposure to xanthones, benzophenones, dihydrochalcones and other bioactive phenolics

Journal of Food Composition and Analysis

Volumn 44, Issue , 2015, Pages 139-148

  Schulze, Alexandra E ^a,b   Beelders, Theresa ^a,b   Koch, Ilona S ^b   Erasmus, Lené M ^b   De Beer, Dalene ^a   Joubert, Elizabeth ^a,b  

^a ARC INFRUITEC NIETVOORBIJ   (South Africa)

^b STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

Benzophenone; Cyclopia spp.; Dihydrochalcone; Flavanone; Flavone; Food analysis; Food composition; HPLC DAD method development; LC DAD MS; Xanthone

Indexed keywords

EID: 84941279809     PISSN: 08891575     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jfca.2015.08.002     Document Type: Article

References (36)

1. Abad-García B., Berrueta L.A., Garmón-Lobato S., Gallo B., Vicente F. A general analytical strategy for the characterization of phenolic compounds in fruit juices by high-performance liquid chromatography with diode array detection coupled to electrospray ionization and triple quadrupole mass spectrometry. J. Chromatogr. A 2009, 1216:5398-5415.
2. Arthur H., Joubert E., de Beer D., Malherbe C.J., Witthuhn R.C. Phenylethanoid glycosides as major antioxidants in Lippia multiflora herbal infusion and their stability during steam pasteurisation of plant material. Food Chem. 2011, 127:581-588.
3. Barati E., Esfahani J.A. A new solution approach for simultaneous heat and mass transfer during convective drying of mango. J. Food Eng. 2011, 102:302-309.
4. Beelders T., Brand D.J., de Beer D., Malherbe C.J., Mazibuko S.E., Muller C.J.F., Joubert E. Benzophenone C- and O-glucosides from Cyclopia genistoides (honeybush) inhibit mammalian α-glucosidase. J. Nat. Prod. 2014, 77:2694-2699.
5. Beelders T., de Beer D., Stander M., Joubert E. Comprehensive phenolic profiling of Cyclopia genistoides (L.) Vent. by LC-DAD-MS and -MS/MS reveals novel xanthone and benzophenone constituents. Molecules 2014, 19:11760-11790.
6. Berardini N., Carle R., Schieber A. Characterization of gallotannins and benzophenone derivatives from mango (Mangifera indica L. cv. 'Tommy Atkins') peels, pulp and kernels by high-performance liquid chromatography/electrospray ionization mass spectrometry. Rapid Commun. Mass Spectrom. 2004, 18:2208-2216.
7. Berardini N., Fezer R., Conrad J., Beifuss U., Carle R., Schieber A. Screening of mango (Mangifera indica L.) cultivars for their contents of flavonol O- and xanthone C-glycosides, anthocyanins, and pectin. J. Agric. Food Chem. 2005, 53:1563-1570.
8. Bhagwat S., Haytowitz D.B., Wasswa-Kintu S.I., Holden J.M. USDA develops a database for flavonoids to assess dietary intakes. Procedia Food Sci. 2013, 2:81-86.
9. de Beer D., Schulze A.E., Joubert E., de Villiers A., Malherbe C.J., Stander M.A. Food ingredient extracts of Cyclopia subternata (honeybush): variation in phenolic composition and antioxidant capacity. Molecules 2012, 17:14602-14624.
10. de la Iglesia R., Lopez-Legarrea P., Celada P., Sánchez-Muniz F., Martinez J., Zulet M. Beneficial effects of the RESMENA dietary pattern on oxidative stress in patients suffering from metabolic syndrome with hyperglycemia are associated to dietary TAC and fruit consumption. Int. J. Mol. Sci. 2013, 14:6903-6919.
11. de Menezes E.W., Santos N.C., Giuntini E.B., Dan M.C.T., Genovese M.I., Lajolo F.M. Brazilian flavonoid database: application of quality evaluation system. J. Food Compos. Anal. 2011, 24:629-636.
12. Feng J., Yang X.-W., Wang R.-F. Bio-assay guided isolation and identification of α-glucosidase inhibitors from the leaves of Aquilaria sinensis. Phytochemistry 2011, 72:242-247.
13. Garg A., Garg S., Zaneveld L.J.D., Singla A.K. Chemistry and pharmacology of the citrus bioflavonoid hesperidin. Phytother. Res. 2001, 15:655-669.
14. Gopalakrishnan S. Marketing system of mangoes in India. World Appl. Sci. J. 2013, 21:1000-1007.
15. Ivey K.L., Hodgson J.M., Croft K.D., Lewis J.R., Prince R.L. Flavonoid intake and all-cause mortality. Am. J. Clin. Nutr. 2015, 101:1012-1020.
16. Joubert E., Beelders T., de Beer D., Malherbe C.J., de Villiers A.J., Sigge G.O. Variation in phenolic content and antioxidant activity of fermented rooibos herbal tea infusions: role of production season and quality grade. J. Agric. Food Chem. 2012, 60:9171-9179.
17. Joubert E., de Beer D. Rooibos (Aspalathus linearis) beyond the farm gate: from herbal tea to potential phytopharmaceutical. S. Afr. J. Bot. 2011, 77:869-886.
18. Joubert E., Joubert M.E., Bester C., de Beer D., de Lange J.H. Honeybush (Cyclopia spp.): from local cottage industry to global markets - the catalytic and supporting role of research. S. Afr. J. Bot. 2011, 77:887-907.
19. Joubert E., Richards E.S., van der Merwe J.D., de Beer D., Manley M., Gelderblom W.C.A. Effect of species variation and processing on phenolic composition and in vitro antioxidant activity of aqueous extracts of Cyclopia spp. (honeybush tea). J. Agric. Food Chem. 2008, 56:954-963.
20. Kamara B.I., Brand D.J., Brandt E.V., Joubert E. Phenolic metabolites from honeybush tea (Cyclopia subternata). J. Agric. Food Chem. 2004, 52:5391-5395.
21. Kokotkiewicz A., Luczkiewicz M., Sowinski P., Glod D., Gorynski K., Bucinski A. Isolation and structure elucidation of phenolic compounds from Cyclopia subternata Vogel (honeybush) intact plant and in vitro cultures. Food Chem. 2012, 133:1373-1382.
22. Lechaudel M., Genard M., Lescourret F., Urban L., Jannoyer M. Leaf-to-fruit ratio affects water and dry-matter content of mango fruit. J. Hortic. Sci. Biotechnol. 2002, 77:773-777.
23. Moreno-Franco B., García-González A., Montero-Bravo A.M., Iglesias-Gutiérrez E., beda N., Maroto-Núñez L., Adlercreutz H., Peñalvo J.L. Dietary alkylresorcinols and lignans in the Spanish diet: development of the Alignia database. J. Agric. Food Chem. 2011, 59:9827-9834.
24. Neveu V., Perez-Jiménez J., Vos F., Crespy V., du Chaffaut L., Mennen L., Knox C., Eisner R., Cruz J., Wishart D., Scalbert A. Phenol-Explorer: an online comprehensive database on polyphenol contents in foods. Database 2010, 10.1093/database/bap024.
25. Obuchowicz J., Engelhardt U.H., Donnelly K. Flavanol database for green and black teas utilising ISO 14502-1 and ISO 14502-2 as analytical tools. J. Food Compos. Anal. 2011, 24:411-417.
26. Pérez-Jiménez J., Neveu V., Vos F., Scalbert A. Systematic analysis of the content of 502 polyphenols in 452 foods and beverages: an application of the Phenol-Explorer database. J. Agric. Food Chem. 2010, 58:4959-4969.
27. Roowi S., Crozier A. Flavonoids in tropical citrus species. J. Agric. Food Chem. 2011, 59:12217-12225.
28. Sánchez-Rabaneda F., Jáuregui O., Lamuela-Raventós R.M., Bastida J., Viladomat F., Codina C. Identification of phenolic compounds in artichoke waste by high-performance liquid chromatography-tandem mass spectrometry. J. Chromatogr. A 2003, 1008:57-72.
29. Schulze A.E., de Beer D., de Villiers A., Manley M., Joubert E. Chemometric analysis of chromatographic fingerprints shows potential of Cyclopia maculata (Andrews) Kies for production of standardized extracts with high xanthone content. J. Agric. Food Chem. 2014, 62:10542-10551.
30. Schutte A.L. Systematics of the genus Cyclopia Vent. (Fabaceae, Podalyrieae). Edinburgh J. Bot. 1997, 54:125-170.
31. Slimestad R., Fossen T., Verheul M.J. The flavonoids of tomatoes. J. Agric. Food Chem. 2008, 56:2436-2441.
32. Theron K.A. Sensory and phenolic profiling of Cyclopia species (honeybush) and optimisation of the fermentation conditions 2012, (MSc (Food Science)), Stellenbosch University, Stellenbosch, South Africa.
33. Valtueña S., Pellegrini N., Franzini L., Bianchi M.A., Ardigò D., Del Rio D., Piatti P., Scazzina F., Zavaroni I., Brighenti F. Food selection based on total antioxidant capacity can modify antioxidant intake, systemic inflammation, and liver function without altering markers of oxidative stress. Am. J. Clin. Nutr. 2008, 87:1290-1297.
34. Vyas A., Syeda K., Ahmad A., Padhye S., Sarkar F.H. Perspectives on medicinal properties of mangiferin. Mini Rev. Med. Chem. 2012, 12:412-425.
35. Watanabe S., Zhuo X.G., Kimira M. Food safety and epidemiology: new database of functional food factors. BioFactors 2004, 22:213-219.
36. Wauthoz N., Balde A., Balde E., van Damme M., Duez P. Ethnopharmacology of Mangifera indica L. bark and pharmacological studies of its main C-glucosylxanthone, mangiferin. Int. J. Biomed. Pharmaceut. Sci. 2007, 1:112-119.