Oligoribonuclease is the primary degradative enzyme for pGpG in Pseudomonas aeruginosa that is required for cyclic-di-GMP turnover

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 36, 2015, Pages E5048-E5057

  Orr, Mona W ^a,b   Donaldson, Gregory P ^a   Severin, Geoffrey B ^c   Wang, Jingxin ^a   Sintim, Herman O ^a   Waters, Christopher M ^d   Lee, Vincent T ^a  

^a Bldg 142   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c Michigan State University   (United States)

^d NONE   (United States)

Author keywords

Cyclic di GMP; Nanornase; Oligoribonuclease; PDE B; PGpG

Indexed keywords

ALANINE; BACTERIAL PROTEIN; BACTERIAL RNA; BETA GALACTOSIDASE; CYCLIC DI GMP; CYCLIC GMP; DIGUANYLATE CYCLASE; EXORIBONUCLEASE; GUANYLATE CYCLASE; OLIGORIBONUCLEASE; PHOSPHODIESTERASE; PHOSPHODIESTERASE B; REGULATOR PROTEIN; RIBONUCLEASE; ROCR PROTEIN; UNCLASSIFIED DRUG; BIS(3',5')-CYCLIC DIGUANYLIC ACID; DEOXYDIGUANOSINE DIPHOSPHOSPHATE; DEOXYGUANOSINE PHOSPHATE; ESCHERICHIA COLI PROTEIN; GUANOSINE PHOSPHATE; LYASE; PROTEIN BINDING;

ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL GENE; BACTERIAL GENOME; BACTERIAL GROWTH; BACTERIAL STRAIN; BINDING AFFINITY; BINDING SITE; BIOFILM; CELL LYSATE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CRYSTAL STRUCTURE; DISSOCIATION CONSTANT; DOWN REGULATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME PURIFICATION; ENZYME REGULATION; ENZYME STRUCTURE; ESCHERICHIA COLI; GENE CONVERSION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HALF LIFE TIME; IN VITRO STUDY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN HYDROLYSIS; PROTEIN METABOLISM; PROTEIN STABILITY; PSEUDOMONAS AERUGINOSA; SURFACE PROPERTY; UPREGULATION; AMINO ACID SEQUENCE; ANALOGS AND DERIVATIVES; ENZYMOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; HOMEOSTASIS; HYDROLYSIS; LIQUID CHROMATOGRAPHY; METABOLISM; MOLECULAR GENETICS; MUTATION; SEQUENCE HOMOLOGY; TANDEM MASS SPECTROMETRY;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BIOFILMS; CHROMATOGRAPHY, LIQUID; CYCLIC GMP; DEOXYGUANINE NUCLEOTIDES; ESCHERICHIA COLI PROTEINS; EXORIBONUCLEASES; GUANOSINE MONOPHOSPHATE; HOMEOSTASIS; HYDROLYSIS; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORIC DIESTER HYDROLASES; PHOSPHORUS-OXYGEN LYASES; PROTEIN BINDING; PSEUDOMONAS AERUGINOSA; SEQUENCE HOMOLOGY, AMINO ACID; TANDEM MASS SPECTROMETRY;

EID: 84941254999     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1507245112     Document Type: Article

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