An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 7, 2015, Pages E747-E756

  Huynh, TuAnh Ngoc ^a   Luo, Shukun ^b   Pensinger, Daniel ^c   Sauer, John Demian ^c   Tong, Liang ^b   Woodward, Joshua J ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Bacterial signal transduction; C di AMP; HD domain; Listeria monocytogenes; Phosphodiesterase

Indexed keywords

ADENOSINE PHOSPHATE; INTERFERON; PHOSPHODIESTERASE; CYCLIC AMP; PROTEIN BINDING;

ALLELE; ARTICLE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENE DELETION; GENETIC ANALYSIS; HYDROLYSIS; LISTERIA MONOCYTOGENES; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; PROTEIN STRUCTURE; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOLECULAR GENETICS; PATHOGENICITY; VIRULENCE;

BACTERIA (MICROORGANISMS); LISTERIA MONOCYTOGENES;

AMINO ACID SEQUENCE; CYCLIC AMP; HYDROLYSIS; LISTERIA MONOCYTOGENES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHORIC DIESTER HYDROLASES; PROTEIN BINDING; VIRULENCE;

EID: 84923165681     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1416485112     Document Type: Article

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