-
1
-
-
0016715526
-
Early breakdown of the blood-retinal barrier in diabetes
-
Cunha-Vaz, J.; de Abreu, J.R.F.; Campos, A.J. Early breakdown of the blood-retinal barrier in diabetes. Br. J. Ophthalmol. 1975, 59, 649–656.
-
(1975)
Br. J. Ophthalmol
, vol.59
, pp. 649-656
-
-
Cunha-Vaz, J.1
De Abreu, J.2
Campos, A.J.3
-
2
-
-
85017907204
-
Mechanisms of blood-retinal barrier breakdown in diabetic retinopathy
-
2nd ed.; Tombran-Tink, J., Barnstable, C.J., et al., Eds.; Springer: New York, NY, USA
-
Hafezi-Moghadam, A. Mechanisms of blood-retinal barrier breakdown in diabetic retinopathy. In Visual Dysfunction in Diabetes, 2nd ed.; Tombran-Tink, J., Barnstable, C.J., et al., Eds.; Springer: New York, NY, USA, 2012; pp. 105–122.
-
(2012)
Visual Dysfunction in Diabetes
, pp. 105-122
-
-
Hafezi-Moghadam, A.1
-
3
-
-
84876729820
-
Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions
-
Klaassen, I.; van Noorden, C.J.F.; Schlingemann, R.O. Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions. Prog. Retin. Eye Res. 2013, 34, 19–48.
-
(2013)
Prog. Retin. Eye Res
, vol.34
, pp. 19-48
-
-
Klaassen, I.1
Van Noorden, C.2
Schlingemann, R.O.3
-
4
-
-
79955943133
-
Is required for late BRB breakdown in diabetic retinopathy, and its inhibition prevents leukostasis and protects vessels and neurons from apoptosis
-
Huang, H.; Gandhi, J.K.; Zhong, X.; Wei, Y.; Gong, J.; Duh, E.J.; Vinores, S.A. TNFα is required for late BRB breakdown in diabetic retinopathy, and its inhibition prevents leukostasis and protects vessels and neurons from apoptosis. Investig. Ophthalmol. Vis. Sci. 2011, 52, 1336–1344.
-
(2011)
Investig. Ophthalmol. Vis. Sci
, vol.52
, pp. 1336-1344
-
-
Huang, H.1
Gandhi, J.K.2
Zhong, X.3
Wei, Y.4
Gong, J.5
Duh, E.J.6
Vinores, S.A.T.7
-
5
-
-
4744347272
-
Role of interleukin-1β in the pathogenesis of diabetic retinopathy
-
Kowluru, R.A.; Odenbach, S. Role of interleukin-1β in the pathogenesis of diabetic retinopathy. Br. J. Ophthalmol. 2004, 88, 1343–1347.
-
(2004)
Br. J. Ophthalmol
, vol.88
, pp. 1343-1347
-
-
Kowluru, R.A.1
Odenbach, S.2
-
6
-
-
84933188835
-
Protective effect of tetramethylpyrazine on myocardial ischemia-reperfusion injury
-
Qian, W.; Xiong, X.; Fang, Z.; Lu, H.; Wang, Z. Protective effect of tetramethylpyrazine on myocardial ischemia-reperfusion injury. Evid. Based Complement. Altern. Med. 2014, 2014, doi:10.1155/2014/107501.
-
(2014)
Evid. Based Complement. Altern. Med
, pp. 2014
-
-
Qian, W.1
Xiong, X.2
Fang, Z.3
Lu, H.4
Wang, Z.5
-
7
-
-
84878857984
-
Tetramethylpyrazine reduces cellular inflammatory response following permanent focal cerebral ischemia in rats
-
Kao, T.K.; Chang, C.Y.; Ou, Y.C.; Chen, W.Y.; Kuan, Y.H.; Pan, H.C.; Liao, S.L.; Li, G.Z.; Chen, C.J. Tetramethylpyrazine reduces cellular inflammatory response following permanent focal cerebral ischemia in rats. Exp. Neurol. 2013, 247, 188–201.
-
(2013)
Exp. Neurol
, vol.247
, pp. 188-201
-
-
Kao, T.K.1
Chang, C.Y.2
Ou, Y.C.3
Chen, W.Y.4
Kuan, Y.H.5
Pan, H.C.6
Liao, S.L.7
Li, G.Z.8
Chen, C.J.9
-
8
-
-
0026937066
-
Ischemic stroke treated with Ligusticum chuanxiong
-
Chen, K.J.; Chen, K. Ischemic stroke treated with Ligusticum chuanxiong. Chin. Med. J. 1992, 105, 870–873.
-
(1992)
Chin. Med. J
, vol.105
, pp. 870-873
-
-
Chen, K.J.1
Chen, K.2
-
9
-
-
84930928547
-
Tetramethylpyrazine (TMP) protects against sodium arsenite-induced nephrotoxicity by suppressing ROS production, mitochondrial dysfunction, pro-inflammatory signaling pathways and programed cell death
-
Gong, X.; Ivanov, V.N.; Davidson, M.M.; Hei, T.K. Tetramethylpyrazine (TMP) protects against sodium arsenite-induced nephrotoxicity by suppressing ROS production, mitochondrial dysfunction, pro-inflammatory signaling pathways and programed cell death. Arch. Toxicol. 2015, 89, 1057–1070.
-
(2015)
Arch. Toxicol
, vol.89
, pp. 1057-1070
-
-
Gong, X.1
Ivanov, V.N.2
Davidson, M.M.3
Hei, T.K.4
-
10
-
-
84862592636
-
TMP prevents retinal neovascularization and imparts neuroprotection in an oxygen-induced retinopathy model
-
Liang, X.; Zhou, H.; Ding, Y.; Li, J.; Yang, C.; Luo, Y.; Li, S.; Sun, G.; Liao, X.; Min, W. TMP prevents retinal neovascularization and imparts neuroprotection in an oxygen-induced retinopathy model. Investig. Ophthalmol. Vis. Sci. 2012, 53, 2157-2169.
-
(2012)
Investig. Ophthalmol. Vis. Sci
, vol.53
, pp. 2157-2169
-
-
Liang, X.1
Zhou, H.2
Ding, Y.3
Li, J.4
Yang, C.5
Luo, Y.6
Li, S.7
Sun, G.8
Liao, X.9
Min, W.10
-
11
-
-
40949084677
-
Protective effects of tetramethylpyrazine on rat retinal cell cultures
-
Yang, Z.; Zhang, Q.; Ge, J.; Tan, Z. Protective effects of tetramethylpyrazine on rat retinal cell cultures. Neurochem. Int. 2008, 52, 1176–1187.
-
(2008)
Neurochem. Int
, vol.52
, pp. 1176-1187
-
-
Yang, Z.1
Zhang, Q.2
Ge, J.3
Tan, Z.4
-
12
-
-
77649221493
-
Mechanism of tetramethylpyrazine analogue CXC195 inhibition of hydrogen peroxide-induced apoptosis in human endothelial cells
-
Ou, Y.; Dong, X.; Liu, X.Y.; Cheng, X.C.; Cheng, Y.N.; Yu, L.G.; Guo, X.L. Mechanism of tetramethylpyrazine analogue CXC195 inhibition of hydrogen peroxide-induced apoptosis in human endothelial cells. Biol. Pharm. Bull. 2010, 33, 432–438.
-
(2010)
Biol. Pharm. Bull
, vol.33
, pp. 432-438
-
-
Ou, Y.1
Dong, X.2
Liu, X.Y.3
Cheng, X.C.4
Cheng, Y.N.5
Yu, L.G.6
Guo, X.L.7
-
13
-
-
22144440162
-
Tetramethylpyrazine protected photoreceptor cells of rats by modulating nuclear translocation of NF-κB
-
Yang, J.N.; Chen, J.M.; Luo, L.; Lin, S.C.; Li, D.; Hu, S.X. Tetramethylpyrazine protected photoreceptor cells of rats by modulating nuclear translocation of NF-κB. Acta Pharmacol. Sin. 2005, 26, 887–892.
-
(2005)
Acta Pharmacol. Sin
, vol.26
, pp. 887-892
-
-
Yang, J.N.1
Chen, J.M.2
Luo, L.3
Lin, S.C.4
Li, D.5
Hu, S.X.6
-
14
-
-
0034779956
-
Conditionally immortalized retinal capillary endothelial cell lines (TR-iBRB) expressing differentiated endothelial cell functions derived from a transgenic rat
-
Hosoya, K.I.; Tomi, M.; Ohtsuki, S.; Takanaga, H.; Ueda, M.; Yanai, N.; Obinata, M.; Terasaki, T. Conditionally immortalized retinal capillary endothelial cell lines (TR-iBRB) expressing differentiated endothelial cell functions derived from a transgenic rat. Exp. Eye Res. 2001, 72, 163–172.
-
(2001)
Exp. Eye Res
, vol.72
, pp. 163-172
-
-
Hosoya, K.I.1
Tomi, M.2
Ohtsuki, S.3
Takanaga, H.4
Ueda, M.5
Yanai, N.6
Obinata, M.7
Terasaki, T.8
-
15
-
-
63849118178
-
Role of nitric oxide, superoxide, peroxynitrite and PARP in diabetic retinopathy
-
Zheng, L.; Kern, T.S. Role of nitric oxide, superoxide, peroxynitrite and PARP in diabetic retinopathy. Front. Biosci. 2009, 14, 3974–3987.
-
(2009)
Front. Biosci
, vol.14
, pp. 3974-3987
-
-
Zheng, L.1
Kern, T.S.2
-
16
-
-
0038243821
-
Experimental diabetes causes breakdown of the blood-retina barrier by a mechanism involving tyrosine nitration and increases in expression of vascular endothelial growth factor and urokinase plasminogen activator receptor
-
El-Remessy, A.B.; Behzadian, M.A.; Abou-Mohamed, G.; Franklin, T.; Caldwell, R.W.; Caldwell, R.B. Experimental diabetes causes breakdown of the blood-retina barrier by a mechanism involving tyrosine nitration and increases in expression of vascular endothelial growth factor and urokinase plasminogen activator receptor. Am. J. Pathol. 2003, 162, 1995–2004.
-
(2003)
Am. J. Pathol
, vol.162
, pp. 1995-2004
-
-
El-Remessy, A.B.1
Behzadian, M.A.2
Abou-Mohamed, G.3
Franklin, T.4
Caldwell, R.W.5
Caldwell, R.B.6
-
17
-
-
0036174019
-
Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo
-
Joussen, A.M.; Poulaki, V.; Qin, W.; Kirchhof, B.; Mitsiades, N.; Wiegand, S.J.; Rudge, J.; Yancopoulos, G.D.; Adamis, A. P. Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo. Am. J. Pathol. 2002, 160, 501–509.
-
(2002)
Am. J. Pathol
, vol.160
, pp. 501-509
-
-
Joussen, A.M.1
Poulaki, V.2
Qin, W.3
Kirchhof, B.4
Mitsiades, N.5
Wiegand, S.J.6
Rudge, J.7
Yancopoulos, G.D.8
Adamis, A.P.9
-
18
-
-
84879165160
-
Oxidative stress: The mitochondria-dependent and mitochondria-independent pathways of apoptosis
-
Sinha, K.; Das, J.; Pal, P.; Sil, P. Oxidative stress: The mitochondria-dependent and mitochondria-independent pathways of apoptosis. Arch. Toxicol. 2013, 87, 1157–1180.
-
(2013)
Arch. Toxicol
, vol.87
, pp. 1157-1180
-
-
Sinha, K.1
Das, J.2
Pal, P.3
Sil, P.4
-
19
-
-
70450205079
-
Apoptosis and human diseases: Mitochondrion damage and lethal role of released cytochrome c as proapoptotic protein
-
Caroppi, P.; Sinibaldi, F.; Fiorucci, L.; Santucci, R. Apoptosis and human diseases: mitochondrion damage and lethal role of released cytochrome c as proapoptotic protein. Curr. Med. Chem. 2009, 16, 4058–4065.
-
(2009)
Curr. Med. Chem
, vol.16
, pp. 4058-4065
-
-
Caroppi, P.1
Sinibaldi, F.2
Fiorucci, L.3
Santucci, R.4
-
20
-
-
84880267827
-
Reactive oxygen species in the activation of MAP kinases
-
Son, Y.; Kim, S.; Chung, H.T.; Pae, H.O. Reactive oxygen species in the activation of MAP kinases. Methods Enzymol. 2013, 528, 27–48.
-
(2013)
Methods Enzymol
, vol.528
, pp. 27-48
-
-
Son, Y.1
Kim, S.2
Chung, H.T.3
Pae, H.O.4
-
21
-
-
84880741015
-
Tetramethylpyrazine attenuates TNF-α-induced iNOS expression in human endothelial cells: Involvement of Syk-mediated activation of PI3K-IKK-IκB signaling pathways
-
Zheng, Z.; Li, Z.; Chen, S.; Pan, J.; Ma, X. Tetramethylpyrazine attenuates TNF-α-induced iNOS expression in human endothelial cells: Involvement of Syk-mediated activation of PI3K-IKK-IκB signaling pathways. Exp. Cell Res. 2013, 319, 2145–2151.
-
(2013)
Exp. Cell Res
, vol.319
, pp. 2145-2151
-
-
Zheng, Z.1
Li, Z.2
Chen, S.3
Pan, J.4
Ma, X.5
-
22
-
-
84855551633
-
Protective effects of ligustrazine on TNF-α-induced endothelial dysfunction
-
Wu, H.J.; Hao, J.; Wang, S.Q.; Jin, B.L.; Chen, X.B. Protective effects of ligustrazine on TNF-α-induced endothelial dysfunction. Eur. J. Pharmacol. 2012, 674, 365–369.
-
(2012)
Eur. J. Pharmacol
, vol.674
, pp. 365-369
-
-
Wu, H.J.1
Hao, J.2
Wang, S.Q.3
Jin, B.L.4
Chen, X.B.5
-
23
-
-
38449108616
-
Forrester, J.V. Inducible nitric oxide synthase isoform is a key mediator of leukostasis and blood-retinal barrier breakdown in diabetic retinopathy. Investig. Ophthalmol. Vis
-
Leal, E.C.; Manivannan, A.; Hosoya, K.; Terasaki, T.; Cunha-Vaz, J.; Ambrosio, A. F.; Forrester, J.V. Inducible nitric oxide synthase isoform is a key mediator of leukostasis and blood-retinal barrier breakdown in diabetic retinopathy. Investig. Ophthalmol. Vis. Sci. 2007, 48, 5257–5265.
-
(2007)
Sci
, vol.48
, pp. 5257-5265
-
-
Leal, E.C.1
Manivannan, A.2
Hosoya, K.3
Terasaki, T.4
Cunha-Vaz, J.5
Ambrosio, A.F.6
-
24
-
-
0032430638
-
Free radicals and antioxidants: Physiology, human pathology and therapeutic aspects (part II)
-
Sahnoun, Z.; Jamoussi, K.; Zeghal, K.M. Free radicals and antioxidants: Physiology, human pathology and therapeutic aspects (part II). Therapie 1998, 53, 315–339.
-
(1998)
Therapie
, vol.53
, pp. 315-339
-
-
Sahnoun, Z.1
Jamoussi, K.2
Zeghal, K.M.3
-
25
-
-
54849431788
-
NF-κB, but not p38 MAP kinase, is required for TNF-α-induced expression of cell adhesion molecules in endothelial cells
-
Rajan, S.; Ye, J.; Bai, S.; Huang, F.; Guo, Y.L. NF-κB, but not p38 MAP kinase, is required for TNF-α-induced expression of cell adhesion molecules in endothelial cells. J. Cell. Biochem. 2008, 105, 477–486.
-
(2008)
J. Cell. Biochem
, vol.105
, pp. 477-486
-
-
Rajan, S.1
Ye, J.2
Bai, S.3
Huang, F.4
Guo, Y.L.5
-
26
-
-
77957589747
-
Calcium dobesilate inhibits the alterations in tight junction proteins and leukocyte adhesion to retinal endothelial cells induced by diabetes
-
Leal, E.C.; Martins, J.; Voabil, P.; Liberal, J.; Chiavaroli, C.; Bauer, J.; Cunha-Vaz, J.; Ambrosio, A.F. Calcium dobesilate inhibits the alterations in tight junction proteins and leukocyte adhesion to retinal endothelial cells induced by diabetes. Diabetes 2010, 59, 2637–2645.
-
(2010)
Diabetes
, vol.59
, pp. 2637-2645
-
-
Leal, E.C.1
Martins, J.2
Voabil, P.3
Liberal, J.4
Chiavaroli, C.5
Bauer, J.6
Cunha-Vaz, J.7
Ambrosio, A.F.8
-
27
-
-
34247394257
-
Oxidative stress and diabetic retinopathy
-
Kowluru, R.A.; Chan, P.S. Oxidative stress and diabetic retinopathy. Exp. Diabetes Res. 2007, 2007, doi:10.1155/2007/43603.
-
(2007)
Exp. Diabetes Res.
, pp. 2007
-
-
Kowluru, R.A.1
Chan, P.S.2
-
29
-
-
0035200658
-
Cellular thiols and reactive oxygen species in drug-induced apoptosis
-
Davis, W.; Ronai, Z.E.; Tew, K.D. Cellular thiols and reactive oxygen species in drug-induced apoptosis. J. Pharmacol. Exp. Ther. 2001, 296, 1–6.
-
(2001)
J. Pharmacol. Exp. Ther
, vol.296
, pp. 1-6
-
-
Davis, W.1
Ronai, Z.E.2
Tew, K.D.3
-
30
-
-
0035426001
-
Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60 cells
-
Anuradha, C.D.; Kanno, S.; Hirano, S. Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60 cells. Free Radic. Biol. Med. 2001, 31, 367–373.
-
(2001)
Free Radic. Biol. Med
, vol.31
, pp. 367-373
-
-
Anuradha, C.D.1
Kanno, S.2
Hirano, S.3
-
31
-
-
65649085279
-
Reactive oxygen species: A double-edged sword in oncogenesis
-
Pan, J.S.; Hong, M.Z.; Ren, J.L. Reactive oxygen species: A double-edged sword in oncogenesis. World J. Gastroenterol. 2009, 15, 1702–1707.
-
(2009)
World J. Gastroenterol
, vol.15
, pp. 1702-1707
-
-
Pan, J.S.1
Hong, M.Z.2
Ren, J.L.3
-
32
-
-
0037032817
-
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
-
Johnson, G.L.; Lapadat, R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002, 298, 1911–1912.
-
(2002)
Science
, vol.298
, pp. 1911-1912
-
-
Johnson, G.L.1
Lapadat, R.2
-
33
-
-
67650227476
-
The transforming growth factor-β pathway is a common target of drugs that prevent experimental diabetic retinopathy
-
Gerhardinger, C.; Dagher, Z.; Sebastiani, P.; Park, Y.S.; Lorenzi, M. The transforming growth factor-β pathway is a common target of drugs that prevent experimental diabetic retinopathy. Diabetes 2009, 58, 1659–1667.
-
(2009)
Diabetes
, vol.58
, pp. 1659-1667
-
-
Gerhardinger, C.1
Dagher, Z.2
Sebastiani, P.3
Park, Y.S.4
Lorenzi, M.5
-
34
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford, M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72, 248–254.
-
(1976)
Anal. Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
35
-
-
4043133743
-
Diallyl disulfide (DADS) induced apoptosis undergo caspase-3 activity in human bladder cancer T24 cells
-
Lu, H.F.; Sue, C.C.; Yu, C.S.; Chen, S.C.; Chen, G.W.; Chung, J. G. Diallyl disulfide (DADS) induced apoptosis undergo caspase-3 activity in human bladder cancer T24 cells. Food Chem. Toxicol. 2004, 42, 1543–1552.
-
(2004)
Food Chem. Toxicol
, vol.42
, pp. 1543-1552
-
-
Lu, H.F.1
Sue, C.C.2
Yu, C.S.3
Chen, S.C.4
Chen, G.W.5
Chung, J.G.6
-
36
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang, J.; Liu, X.; Bhalla, K.; Kim, C.N.; Ibrado, A.M.; Cai, J.; Peng, T.I.; Jones, D.P.; Wang, X. Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked. Science 1997, 275, 1129–1132.
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
Kim, C.N.4
Ibrado, A.M.5
Cai, J.6
Peng, T.I.7
Jones, D.P.8
Wang, X.9
|