APP intracellular domain-WAVE1 pathway reduces amyloid-β production

Nature Medicine

Volumn 21, Issue 9, 2015, Pages 1054-1059

  Ceglia, Ilaria ^a   Reitz, Christiane ^b,c,d   Gresack, Jodi ^a   Ahn, Jung Hyuck ^e,f   Bustos, Victor ^a   Bleck, Marina ^a   Zhang, Xiaozhu ^a   Martin, Grant ^a   Simon, Sanford M ^a   Nairn, Angus C ^a,g   Greengard, Paul ^a   Kim, Yong ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b Department of Medicine   (United States)

^c Vagelos College of Physicians and Surgeons   (United States)

^d Yale University School of Medicine ^*  (United States)

^e Ewha Womans University   (South Korea)

^f Ewha Womans University School of Medicine   (South Korea)

^g YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE INHIBITOR; MESSENGER RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AICD; UNCLASSIFIED DRUG; WAVE1 PROTEIN; WISKOTT ALDRICH SYNDROME PROTEIN;

ALZHEIMER DISEASE; AMNESIA; AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CELL BUDDING; CELL SURFACE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DOWN REGULATION; ENDOSOME; GENE EXPRESSION; GENE OVEREXPRESSION; GOLGI COMPLEX; HIPPOCAMPUS; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; MOUSE MODEL; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; TRANS GOLGI NETWORK; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CHEMISTRY; GENETICS; HUMAN; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BASE SEQUENCE; CELLS, CULTURED; HUMANS; MALE; MICE; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY;

EID: 84941022788     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3924     Document Type: Article

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