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Volumn 65, Issue 12, 2016, Pages 1938-1950

MIR-301a promotes intestinal mucosal inflammation through induction of IL-17A and TNF-α in IBD

Author keywords

IBD BASIC RESEARCH; IMMUNOREGULATION; MUCOSAL IMMUNITY

Indexed keywords

INFLIXIMAB; INTERLEUKIN 17; MICRORNA; MICRORNA 301A; NUCLEAR PROTEIN; SNIP1 PROTEIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; MIRN301 MICRORNA, HUMAN;

EID: 84940919418     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2015-309389     Document Type: Article
Times cited : (140)

References (46)
  • 1
    • 84885658881 scopus 로고    scopus 로고
    • Recent advances in inflammatory bowel disease: Mucosal immune cells in intestinal inflammation
    • Cader MZ, Kaser A. Recent advances in inflammatory bowel disease: mucosal immune cells in intestinal inflammation. Gut 2013;62:1653-64.
    • (2013) Gut , vol.62 , pp. 1653-1664
    • Cader, M.Z.1    Kaser, A.2
  • 2
    • 84884273778 scopus 로고    scopus 로고
    • Advances in inflammatory bowel disease pathogenesis: Linking host genetics and the microbiome
    • Knights D, Lassen KG, Xavier RJ. Advances in inflammatory bowel disease pathogenesis: linking host genetics and the microbiome. Gut 2013;62: 1505-10.
    • (2013) Gut , vol.62 , pp. 1505-1510
    • Knights, D.1    Lassen, K.G.2    Xavier, R.J.3
  • 3
    • 84939478859 scopus 로고    scopus 로고
    • Regulatory immune cells in regulation of intestinal inflammatory response to microbiota
    • Sun M, He C, Cong Y, et al. Regulatory immune cells in regulation of intestinal inflammatory response to microbiota. Mucosal Immunol 2015;8:969-78.
    • (2015) Mucosal Immunol , vol.8 , pp. 969-978
    • Sun, M.1    He, C.2    Cong, Y.3
  • 4
    • 84898010808 scopus 로고    scopus 로고
    • Long-term intake of dietary fat and risk of ulcerative colitis and Crohn's disease
    • Ananthakrishnan AN, Khalili H, Konijeti GG, et al. Long-term intake of dietary fat and risk of ulcerative colitis and Crohn's disease. Gut 2014;63:776-84.
    • (2014) Gut , vol.63 , pp. 776-784
    • Ananthakrishnan, A.N.1    Khalili, H.2    Konijeti, G.G.3
  • 5
    • 84920971304 scopus 로고    scopus 로고
    • Does the microbiota play a role in the pathogenesis of autoimmune diseases?
    • McLean MH, Dieguez D Jr, Miller LM, et al. Does the microbiota play a role in the pathogenesis of autoimmune diseases? Gut 2015;64:332-41.
    • (2015) Gut , vol.64 , pp. 332-341
    • McLean, M.H.1    Dieguez, D.2    Miller, L.M.3
  • 6
    • 84934936350 scopus 로고    scopus 로고
    • Environmental risk factors in inflammatory bowel disease: A population-based case-control study in Asia-pacific
    • Ng SC, Tang W, Leong RW, et al. Environmental risk factors in inflammatory bowel disease: a population-based case-control study in Asia-Pacific. Gut 2015;64:1063-71.
    • (2015) Gut , vol.64 , pp. 1063-1071
    • Ng, S.C.1    Tang, W.2    Leong, R.W.3
  • 7
    • 34250026960 scopus 로고    scopus 로고
    • Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice
    • Elson CO, Cong Y, Weaver CT, et al. Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice. Gastroenterology 2007;132: 2359-70.
    • (2007) Gastroenterology , vol.132 , pp. 2359-2370
    • Elson, C.O.1    Cong, Y.2    Weaver, C.T.3
  • 8
    • 13244283212 scopus 로고    scopus 로고
    • IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
    • Langrish CL, Chen Y, Blumenschein WM, et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005;201: 233-40.
    • (2005) J Exp Med , vol.201 , pp. 233-240
    • Langrish, C.L.1    Chen, Y.2    Blumenschein, W.M.3
  • 9
    • 9644291539 scopus 로고    scopus 로고
    • IL-12 and IL-23: Master regulators of innate and adaptive immunity
    • Langrish CL, McKenzie BS, Wilson NJ, et al. IL-12 and IL-23: master regulators of innate and adaptive immunity. Immunol Rev 2004;202:96-105.
    • (2004) Immunol Rev , vol.202 , pp. 96-105
    • Langrish, C.L.1    McKenzie, B.S.2    Wilson, N.J.3
  • 10
    • 84922354753 scopus 로고    scopus 로고
    • MicroRNAs: New players in IBD
    • Kalla R, Ventham NT, Kennedy NA, et al. MicroRNAs: new players in IBD. Gut 2015;64:504-17.
    • (2015) Gut , vol.64 , pp. 504-517
    • Kalla, R.1    Ventham, N.T.2    Kennedy, N.A.3
  • 11
    • 70350435670 scopus 로고    scopus 로고
    • An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA MIR-181a
    • Ebert PJ, Jiang S, Xie J, et al. An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a. Nat Immunol 2009;10:1162-9.
    • (2009) Nat Immunol , vol.10 , pp. 1162-1169
    • Ebert, P.J.1    Jiang, S.2    Xie, J.3
  • 12
    • 77956632634 scopus 로고    scopus 로고
    • Function of MIR-146a in controlling treg cell-mediated regulation of Th1 responses
    • Lu LF, Boldin MP, Chaudhry A, et al. Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses. Cell 2010;142:914-29.
    • (2010) Cell , vol.142 , pp. 914-929
    • Lu, L.F.1    Boldin, M.P.2    Chaudhry, A.3
  • 13
    • 77958495102 scopus 로고    scopus 로고
    • MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development
    • O'Connell RM, Kahn D, Gibson WS, et al. MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development. Immunity 2010;33:607-19.
    • (2010) Immunity , vol.33 , pp. 607-619
    • O'Connell, R.M.1    Kahn, D.2    Gibson, W.S.3
  • 14
    • 78651247933 scopus 로고    scopus 로고
    • MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU.1 pathway
    • Ponomarev ED, Veremeyko T, Barteneva N, et al. MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU.1 pathway. Nat Med 2011;17:64-70.
    • (2011) Nat Med , vol.17 , pp. 64-70
    • Ponomarev, E.D.1    Veremeyko, T.2    Barteneva, N.3
  • 16
    • 83555161689 scopus 로고    scopus 로고
    • MicroRNAs in inflammatory bowel disease
    • Pekow JR, Kwon JH. MicroRNAs in inflammatory bowel disease. Inflamm Bowel Dis 2012;18:187-93.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 187-193
    • Pekow, J.R.1    Kwon, J.H.2
  • 17
    • 78649231641 scopus 로고    scopus 로고
    • Identification of microRNAs associated with ileal and colonic Crohn's disease
    • Wu F, Zhang S, Dassopoulos T, et al. Identification of microRNAs associated with ileal and colonic Crohn's disease. Inflamm Bowel Dis 2010;16:1729-38.
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 1729-1738
    • Wu, F.1    Zhang, S.2    Dassopoulos, T.3
  • 18
    • 84908270734 scopus 로고    scopus 로고
    • MIR-155 deficiency protects mice from experimental colitis by reducing T helper type 1/type 17 responses
    • Singh UP, Murphy AE, Enos RT, et al. miR-155 deficiency protects mice from experimental colitis by reducing T helper type 1/type 17 responses. Immunology 2014;143:478-89.
    • (2014) Immunology , vol.143 , pp. 478-489
    • Singh, U.P.1    Murphy, A.E.2    Enos, R.T.3
  • 19
    • 84904042118 scopus 로고    scopus 로고
    • MIR-141 regulates colonic leukocytic trafficking by targeting CXCL12beta during murine colitis and human Crohn's disease
    • Huang Z, Shi T, Zhou Q, et al. miR-141 regulates colonic leukocytic trafficking by targeting CXCL12beta during murine colitis and human Crohn's disease. Gut 2014;63:1247-57.
    • (2014) Gut , vol.63 , pp. 1247-1257
    • Huang, Z.1    Shi, T.2    Zhou, Q.3
  • 20
    • 84947608239 scopus 로고    scopus 로고
    • MIR-10a inhibits dendritic cell activation and Th1/Th17 cell immune responses in IBD
    • Wu W, He C, Liu C, et al. miR-10a inhibits dendritic cell activation and Th1/Th17 cell immune responses in IBD. Gut 2015;64:1755-64.
    • (2015) Gut , vol.64 , pp. 1755-1764
    • Wu, W.1    He, C.2    Liu, C.3
  • 21
    • 84877348831 scopus 로고    scopus 로고
    • Overexpressed MIR-301a promotes cell proliferation and invasion by targeting RUNX3 in gastric cancer
    • Wang M, Li C, Yu B, et al. Overexpressed miR-301a promotes cell proliferation and invasion by targeting RUNX3 in gastric cancer. J Gastroenterol 2013;48: 1023-33.
    • (2013) J Gastroenterol , vol.48 , pp. 1023-1033
    • Wang, M.1    Li, C.2    Yu, B.3
  • 22
    • 78650858038 scopus 로고    scopus 로고
    • MIR-301a as an NF-kappaB activator in pancreatic cancer cells
    • Lu Z, Li Y, Takwi A, et al. miR-301a as an NF-kappaB activator in pancreatic cancer cells. EMBO J 2011;30:57-67.
    • (2011) EMBO J , vol.30 , pp. 57-67
    • Lu, Z.1    Li, Y.2    Takwi, A.3
  • 23
    • 84861207616 scopus 로고    scopus 로고
    • MicroRNA-301a regulation of a T-helper 17 immune response controls autoimmune demyelination
    • Mycko MP, Cichalewska M, Machlanska A, et al. MicroRNA-301a regulation of a T-helper 17 immune response controls autoimmune demyelination. Proc Natl Acad Sci USA 2012;109:E1248-57.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. E1248-E1257
    • Mycko, M.P.1    Cichalewska, M.2    Machlanska, A.3
  • 24
    • 0024552818 scopus 로고
    • Hapten-induced model of chronic inflammation and ulceration in the rat colon
    • Morris GP, Beck PL, Herridge MS, et al. Hapten-induced model of chronic inflammation and ulceration in the rat colon. Gastroenterology 1989;96:795-803.
    • (1989) Gastroenterology , vol.96 , pp. 795-803
    • Morris, G.P.1    Beck, P.L.2    Herridge, M.S.3
  • 25
    • 0028861975 scopus 로고
    • Antibodies to interleukin 12 abrogate established experimental colitis in mice
    • Neurath MF, Fuss I, Kelsall BL, et al. Antibodies to interleukin 12 abrogate established experimental colitis in mice. J Exp Med 1995;182:1281-90.
    • (1995) J Exp Med , vol.182 , pp. 1281-1290
    • Neurath, M.F.1    Fuss, I.2    Kelsall, B.L.3
  • 26
    • 0029836444 scopus 로고    scopus 로고
    • Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice
    • Neurath MF, Pettersson S, Meyer zum Buschenfelde KH, et al. Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice. Nat Med 1996;2:998-1004.
    • (1996) Nat Med , vol.2 , pp. 998-1004
    • Neurath, M.F.1    Pettersson, S.2    Meyer Zum-Buschenfelde, K.H.3
  • 27
    • 84893908765 scopus 로고    scopus 로고
    • Prolactin mediates psychological stress-induced dysfunction of regulatory T cells to facilitate intestinal inflammation
    • Wu W, Sun M, Zhang HP, et al. Prolactin mediates psychological stress-induced dysfunction of regulatory T cells to facilitate intestinal inflammation. Gut 2014;63:1883-92.
    • (2014) Gut , vol.63 , pp. 1883-1892
    • Wu, W.1    Sun, M.2    Zhang, H.P.3
  • 28
    • 84926431532 scopus 로고    scopus 로고
    • Infliximab preferentially induces clinical remission and mucosal healing in short course Crohn's disease with luminal lesions through balancing abnormal immune response in gut mucosa
    • Yu L, Yang X, Xia L, et al. Infliximab preferentially induces clinical remission and mucosal healing in short course Crohn's disease with luminal lesions through balancing abnormal immune response in gut mucosa. Mediators Inflamm 2015;2015:793764.
    • (2015) Mediators Inflamm , vol.2015 , pp. 793764
    • Yu, L.1    Yang, X.2    Xia, L.3
  • 29
    • 84920990831 scopus 로고    scopus 로고
    • Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNFalpha therapy
    • Leal RF, Planell N, Kajekar R, et al. Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNFalpha therapy. Gut 2015;64:233-42.
    • (2015) Gut , vol.64 , pp. 233-242
    • Leal, R.F.1    Planell, N.2    Kajekar, R.3
  • 30
    • 4744375545 scopus 로고    scopus 로고
    • Development and validation of a new, simplified endoscopic activity score for Crohn's disease: The SES-CD
    • Daperno M, D'Haens G, Van Assche G, et al. Development and validation of a new, simplified endoscopic activity score for Crohn's disease: the SES-CD. Gastrointest Endosc 2004;60:505-12.
    • (2004) Gastrointest Endosc , vol.60 , pp. 505-512
    • Daperno, M.1    D'Haens, G.2    Van Assche, G.3
  • 31
    • 84903605028 scopus 로고    scopus 로고
    • Intestinal wall thickness detected by multidetector spiral computed tomography enterography predicts the disease severity of Crohn's disease
    • Yang X, Yu L, Yu W, et al. Intestinal wall thickness detected by multidetector spiral computed tomography enterography predicts the disease severity of Crohn's disease. Scand J Gastroenterol 2014;49:807-13.
    • (2014) Scand J Gastroenterol , vol.49 , pp. 807-813
    • Yang, X.1    Yu, L.2    Yu, W.3
  • 32
    • 0033214529 scopus 로고    scopus 로고
    • Hyperexpression of CD40 ligand (CD154) in inflammatory bowel disease and its contribution to pathogenic cytokine production
    • Liu Z, Colpaert S, D'Haens GR, et al. Hyperexpression of CD40 ligand (CD154) in inflammatory bowel disease and its contribution to pathogenic cytokine production. J Immunol 1999;163:4049-57.
    • (1999) J Immunol , vol.163 , pp. 4049-4057
    • Liu, Z.1    Colpaert, S.2    D'Haens, G.R.3
  • 33
    • 84922628709 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 endues monocytes with immune suppressive ability to inhibit inflammation in the intestine
    • Ge RT, Mo LH, Wu R, et al. Insulin-like growth factor-1 endues monocytes with immune suppressive ability to inhibit inflammation in the intestine. Sci Rep 2015;5:7735.
    • (2015) Sci Rep , vol.5 , pp. 7735
    • Ge, R.T.1    Mo, L.H.2    Wu, R.3
  • 34
    • 79958130907 scopus 로고    scopus 로고
    • Interleukin-12 converts foxp3+ regulatory T cells to interferon-gamma-producing foxp3+ T cells that inhibit colitis
    • Feng T, Cao AT, Weaver CT, et al. Interleukin-12 converts Foxp3+ regulatory T cells to interferon-gamma-producing Foxp3+ T cells that inhibit colitis. Gastroenterology 2011;140:2031-43.
    • (2011) Gastroenterology , vol.140 , pp. 2031-2043
    • Feng, T.1    Cao, A.T.2    Weaver, C.T.3
  • 35
    • 34548125305 scopus 로고    scopus 로고
    • Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells
    • Acosta-Rodriguez EV, Napolitani G, Lanzavecchia A, et al. Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immunol 2007;8:942-9.
    • (2007) Nat Immunol , vol.8 , pp. 942-949
    • Acosta-Rodriguez, E.V.1    Napolitani, G.2    Lanzavecchia, A.3
  • 36
    • 34548133583 scopus 로고    scopus 로고
    • Development, cytokine profile and function of human interleukin 17-producing helper T cells
    • Wilson NJ, Boniface K, Chan JR, et al. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol 2007;8:950-7.
    • (2007) Nat Immunol , vol.8 , pp. 950-957
    • Wilson, N.J.1    Boniface, K.2    Chan, J.R.3
  • 37
    • 0035824692 scopus 로고    scopus 로고
    • SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators
    • Kim RH, Flanders KC, Birkey Reffey S, et al. SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators. J Biol Chem 2001;276:46297-304.
    • (2001) J Biol Chem , vol.276 , pp. 46297-46304
    • Kim, R.H.1    Flanders, K.C.2    Birkey Reffey, S.3
  • 38
    • 84897051446 scopus 로고    scopus 로고
    • Negative regulation of hif1a expression and TH17 differentiation by the hypoxia-regulated microRNA MIR-210
    • Wang H, Flach H, Onizawa M, et al. Negative regulation of Hif1a expression and TH17 differentiation by the hypoxia-regulated microRNA miR-210. Nat Immunol 2014;15:393-401.
    • (2014) Nat Immunol , vol.15 , pp. 393-401
    • Wang, H.1    Flach, H.2    Onizawa, M.3
  • 39
    • 70449716915 scopus 로고    scopus 로고
    • MicroRNA MIR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis
    • Du C, Liu C, Kang J, et al. MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis. Nat Immunol 2009;10:1252-9.
    • (2009) Nat Immunol , vol.10 , pp. 1252-1259
    • Du, C.1    Liu, C.2    Kang, J.3
  • 40
    • 84924028501 scopus 로고    scopus 로고
    • MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis
    • Murugaiyan G, da Cunha AP, Ajay AK, et al. MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis. J Clin Invest 2015;125:1069-80.
    • (2015) J Clin Invest , vol.125 , pp. 1069-1080
    • Murugaiyan, G.1    Da Cunha, A.P.2    Ajay, A.K.3
  • 41
    • 84899482237 scopus 로고    scopus 로고
    • Inhibition of MIR-25 improves cardiac contractility in the failing heart
    • Wahlquist C, Jeong D, Rojas-Munoz A, et al. Inhibition of miR-25 improves cardiac contractility in the failing heart. Nature 2014;508:531-5.
    • (2014) Nature , vol.508 , pp. 531-535
    • Wahlquist, C.1    Jeong, D.2    Rojas-Munoz, A.3
  • 42
    • 84929069226 scopus 로고    scopus 로고
    • Neurotensin-regulated MIR-133alpha is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis
    • Law IK, Bakirtzi K, Polytarchou C, et al. Neurotensin-regulated miR-133alpha is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis. Gut 2015;64:1095-104.
    • (2015) Gut , vol.64 , pp. 1095-1104
    • Law, I.K.1    Bakirtzi, K.2    Polytarchou, C.3
  • 43
    • 0037029649 scopus 로고    scopus 로고
    • The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease
    • Neurath MF, Weigmann B, Finotto S, et al. The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease. J Exp Med 2002;195:1129-43.
    • (2002) J Exp Med , vol.195 , pp. 1129-1143
    • Neurath, M.F.1    Weigmann, B.2    Finotto, S.3
  • 44
    • 84922749649 scopus 로고    scopus 로고
    • TIR-domain-containing adapter-inducing interferon-beta (TRIF) regulates Th17-mediated intestinal immunopathology in colitis
    • Kanagavelu S, Flores C, Termini JM, et al. TIR-domain-containing adapter-inducing interferon-beta (TRIF) regulates Th17-mediated intestinal immunopathology in colitis. Mucosal Immunol 2015;8:296-306.
    • (2015) Mucosal Immunol , vol.8 , pp. 296-306
    • Kanagavelu, S.1    Flores, C.2    Termini, J.M.3
  • 45
    • 33646804892 scopus 로고    scopus 로고
    • Critical role of IL-17 receptor signaling in acute TNBS-induced colitis
    • Zhang Z, Zheng M, Bindas J, et al. Critical role of IL-17 receptor signaling in acute TNBS-induced colitis. Inflamm Bowel Dis 2006;12:382-8.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 382-388
    • Zhang, Z.1    Zheng, M.2    Bindas, J.3
  • 46
    • 79960736362 scopus 로고    scopus 로고
    • Targeting IL-12/IL-23 by employing a p40 peptide-based vaccine ameliorates TNBS-induced acute and chronic murine colitis
    • Guan Q, Ma Y, Hillman CL, et al. Targeting IL-12/IL-23 by employing a p40 peptide-based vaccine ameliorates TNBS-induced acute and chronic murine colitis. Mol Med 2011;17:646-56.
    • (2011) Mol Med , vol.17 , pp. 646-656
    • Guan, Q.1    Ma, Y.2    Hillman, C.L.3


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