MicroRNAs in inflammatory bowel disease

Inflammatory Bowel Diseases

Volumn 18, Issue 1, 2012, Pages 187-193

  Pekow, Joel R ^a   Kwon, John H ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

IBD; inflammatory bowel disease; microRNAs

Indexed keywords

BETA INTERFERON; EPIDERMAL GROWTH FACTOR RECEPTOR; I KAPPA B; INTERLEUKIN 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERSTITIAL COLLAGENASE; MICRORNA; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; VASCULOTROPIN RECEPTOR;

ADAPTIVE IMMUNITY; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; AUTOIMMUNE DISEASE; B LYMPHOCYTE; CELL ACTIVITY; COLON CARCINOGENESIS; COLORECTAL CARCINOMA; CROHN DISEASE; DISEASE ASSOCIATION; DISEASE MARKER; DISEASE PREDISPOSITION; DNA POLYMORPHISM; ENTERITIS; GENE EXPRESSION; HUMAN; IMMUNE RESPONSE; IN VIVO STUDY; INFLAMMATION; INNATE IMMUNITY; KERATINOCYTE; LEUKOCYTE DIFFERENTIAL COUNT; LUPUS ERYTHEMATOSUS NEPHRITIS; MACROPHAGE ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PSORIASIS; REVIEW; RHEUMATOID ARTHRITIS; RNA ANALYSIS; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; ULCERATIVE COLITIS; UPREGULATION;

GENE EXPRESSION REGULATION; HUMANS; INFLAMMATORY BOWEL DISEASES; MICRORNAS;

EID: 83555161689     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.21691     Document Type: Review

References (76)

1. Lawrance IC, Fiocchi C, Chakravarti S,. Ulcerative colitis and Crohn's disease: distinctive gene expression profiles and novel susceptibility candidate genes. Hum Mol Genet. 2001; 10: 445-456. (Pubitemid 32181667)
2. Noble CL, Abbas AR, Cornelius J, et al. Regional variation in gene expression in the healthy colon is dysregulated in ulcerative colitis. Gut. 2008; 57: 1398-1405.
3. Okahara S, Arimura Y, Yabana T, et al. Inflammatory gene signature in ulcerative colitis with cDNA macroarray analysis. Aliment Pharmacol Ther. 2005; 21: 1091-1097. (Pubitemid 40646534)
4. Wu F, Dassopoulos T, Cope L, et al. Genome-wide gene expression differences in Crohn's disease and ulcerative colitis from endoscopic pinch biopsies: insights into distinctive pathogenesis. Inflamm Bowel Dis. 2007; 13: 807-821. (Pubitemid 47203859)
5. Mesko B, Poliska S, Szegedi A, et al. Peripheral blood gene expression patterns discriminate among chronic inflammatory diseases and healthy controls and identify novel targets. BMC Med Genomics. 2010; 3: 15.
6. Fujino S, Andoh A, Bamba S, et al. Increased expression of interleukin 17 in inflammatory bowel disease. Gut. 2003; 52: 65-70. (Pubitemid 36020767)
7. Fuss IJ, Heller F, Boirivant M, et al. Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis. J Clin Invest. 2004; 113: 1490-1497. (Pubitemid 39071705)
8. Abraham C, Cho JH,. Inflammatory bowel disease. N Engl J Med. 2009; 361: 2066-2078.
9. Rybaczyk L, Rozmiarek A, Circle K, et al. New bioinformatics approach to analyze gene expressions and signaling pathways reveals unique purine gene dysregulation profiles that distinguish between CD and UC. Inflamm Bowel Dis. 2009; 15: 971-984.
10. Arijs I, Li K, Toedter G, et al. Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis. Gut. 2009; 58: 1612-1619.
11. Bartel DP,. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004; 116: 281-297.
12. Lewis BP, Burge CB, Bartel DP,. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 2005; 120: 15-20. (Pubitemid 40094598)
13. Lewis BP, Shih IH, Jones-Rhoades MW, et al. Prediction of mammalian microRNA targets. Cell. 2003; 115: 787-798. (Pubitemid 38058492)
14. Friedman RC, Farh KK, Burge CB, et al. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 2009; 19: 92-105.
15. Liu W, Mao SY, Zhu WY,. Impact of tiny miRNAs on cancers. World J Gastroenterol. 2007; 13: 497-502. (Pubitemid 46210914)
16. Ambros V,. The functions of animal microRNAs. Nature. 2004; 431: 350-355. (Pubitemid 39265675)
17. McKenna LB, Schug J, Vourekas A, et al. MicroRNAs control intestinal epithelial differentiation, architecture, and barrier function. Gastroenterology. 2010; 139: 1654-1664, 1664 e1651.
18. He L, Thomson JM, Hemann MT, et al. A microRNA polycistron as a potential human oncogene. Nature. 2005; 435: 828-833. (Pubitemid 40839734)
19. Lee RC, Feinbaum RL, Ambros V,. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell. 1993; 75: 843-854. (Pubitemid 24014542)
20. Griffiths-Jones S, Grocock RJ, van Dongen S, et al. miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006; 34: D140-144.
21. Lee Y, Ahn C, Han J, et al. The nuclear RNase III Drosha initiates microRNA processing. Nature. 2003; 425: 415-419. (Pubitemid 37187272)
22. Yi R, Qin Y, Macara IG, et al. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 2003; 17: 3011-3016. (Pubitemid 38040764)
23. Lund E, Guttinger S, Calado A, et al. Nuclear export of microRNA precursors. Science. 2004; 303: 95-98. (Pubitemid 38055779)
24. Robb GB, Rana TM,. RNA helicase A interacts with RISC in human cells and functions in RISC loading. Mol Cell. 2007; 26: 523-537. (Pubitemid 46765183)
25. Kong YW, Cannell IG, de Moor CH, et al. The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene. Proc Natl Acad Sci U S A. 2008; 105: 8866-8871.
26. Lu LF, Liston A,. MicroRNA in the immune system, microRNA as an immune system. Immunology. 2009; 127: 291-298.
27. Dunne A, O'Neill LA,. Adaptor usage and Toll-like receptor signaling specificity. FEBS Lett. 2005; 579: 3330-3335. (Pubitemid 40804682)
28. Kracht M, Saklatvala J,. Transcriptional and post-transcriptional control of gene expression in inflammation. Cytokine. 2002; 20: 91-106. (Pubitemid 35370689)
29. Taganov KD, Boldin MP, Chang KJ, et al. NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci U S A. 2006; 103: 12481-12486. (Pubitemid 44267285)
30. Bazzoni F, Rossato M, Fabbri M, et al. Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals. Proc Natl Acad Sci U S A. 2009; 106: 5282-5287.
31. Selbach M, Schwanhausser B, Thierfelder N, et al. Widespread changes in protein synthesis induced by microRNAs. Nature. 2008; 455: 58-63.
32. Korb M, Rust AG, Thorsson V, et al. The Innate Immune Database (IIDB). BMC Immunol. 2008; 9: 7.
33. Gantier MP,. New perspectives in MicroRNA regulation of innate immunity. J Interferon Cytokine Res. 2010; 30: 283-289.
34. O'Connell RM, Taganov KD, Boldin MP, et al. MicroRNA-155 is induced during the macrophage inflammatory response. Proc Natl Acad Sci U S A. 2007; 104: 1604-1609. (Pubitemid 46214637)
35. Tili E, Michaille JJ, Cimino A, et al. Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J Immunol. 2007; 179: 5082-5089.
36. Ceppi M, Pereira PM, Dunand-Sauthier I, et al. MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells. Proc Natl Acad Sci U S A. 2009; 106: 2735-2740.
37. Lu LF, Thai TH, Calado DP, et al. Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein. Immunity. 2009; 30: 80-91.
38. Rodriguez A, Vigorito E, Clare S, et al. Requirement of bic/microRNA-155 for normal immune function. Science. 2007; 316: 608-611. (Pubitemid 46683148)
39. Zhou X, Jeker LT, Fife BT, et al. Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity. J Exp Med. 2008; 205: 1983-1991.
40. Chen CZ, Li L, Lodish HF, et al. MicroRNAs modulate hematopoietic lineage differentiation. Science. 2004; 303: 83-86. (Pubitemid 38055775)
41. Eis PS, Tam W, Sun L, et al. Accumulation of miR-155 and BIC RNA in human B cell lymphomas. Proc Natl Acad Sci U S A. 2005; 102: 3627-3632. (Pubitemid 40354662)
42. Thai TH, Calado DP, Casola S, et al. Regulation of the germinal center response by microRNA-155. Science. 2007; 316: 604-608. (Pubitemid 46683147)
43. Zhou B, Wang S, Mayr C, et al. miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely. Proc Natl Acad Sci U S A. 2007; 104: 7080-7085. (Pubitemid 47186012)
44. Alevizos I, Illei GG,. MicroRNAs as biomarkers in rheumatic diseases. Nat Rev Rheumatol. 2010; 6: 391-398.
45. Nakasa T, Miyaki S, Okubo A, et al. Expression of microRNA-146 in rheumatoid arthritis synovial tissue. Arthritis Rheum. 2008; 58: 1284-1292. (Pubitemid 351705917)
46. Stanczyk J, Pedrioli DM, Brentano F, et al. Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis. Arthritis Rheum. 2008; 58: 1001-1009. (Pubitemid 351564001)
47. Stanczyk J, Ospelt C, Karouzakis E, et al. Altered expression of miR-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation. Arthritis Rheum. 2011; 63: 373-381.
48. Pauley KM, Satoh M, Chan AL, et al. Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Res Ther. 2008; 10: R101.
49. Dai Y, Huang YS, Tang M, et al. Microarray analysis of microRNA expression in peripheral blood cells of systemic lupus erythematosus patients. Lupus. 2007; 16: 939-946.
50. Tang Y, Luo X, Cui H, et al. MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins. Arthritis Rheum. 2009; 60: 1065-1075.
51. Zhang J, Yang B, Ying B, et al. Association of pre-microRNAs genetic variants with susceptibility in systemic lupus erythematosus. Mol Biol Rep. 2011; 38: 1463-1468.
52. Te JL, Dozmorov IM, Guthridge JM, et al. Identification of unique microRNA signature associated with lupus nephritis. PLoS One. 2010; 5: e10344.
53. Sonkoly E, Wei T, Janson PC, et al. MicroRNAs: novel regulators involved in the pathogenesis of psoriasis? PLoS One. 2007; 2: e610.
54. Sano S, Chan KS, Carbajal S, et al. Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model. Nat Med. 2005; 11: 43-49. (Pubitemid 40215836)
55. Wu F, Zikusoka M, Trindade A, et al. MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha. Gastroenterology. 2008; 135: 1624-1635 e1624.
56. Takagi T, Naito Y, Mizushima K, et al. Increased expression of microRNA in the inflamed colonic mucosa of patients with active ulcerative colitis. J Gastroenterol Hepatol. 2010; 25 (suppl 1): S129-133.
57. Fasseu M, Treton X, Guichard C, et al. Identification of restricted subsets of mature microRNA abnormally expressed in inactive colonic mucosa of patients with inflammatory bowel disease. PLoS One. 2010; 5: e13160.
58. Wu F, Zhang S, Dassopoulos T, et al. Identification of microRNAs associated with ileal and colonic Crohn's disease. Inflamm Bowel Dis. 2010; 16: 1729-1738.
59. Wu F, Guo NJ, Tian H, et al. Peripheral blood microRNAs distinguish active ulcerative colitis and Crohn's disease. Inflamm Bowel Dis. 2011; 17: 241-250.
60. Okubo M, Tahara T, Shibata T, et al. Association study of common genetic variants in pre-microRNAs in patients with ulcerative colitis. J Clin Immunol. 2010; [Epub ahead of print].
61. Hu Z, Chen J, Tian T, et al. Genetic variants of miRNA sequences and non-small cell lung cancer survival. J Clin Invest. 2008; 118: 2600-2608. (Pubitemid 351949787)
62. Tian T, Shu Y, Chen J, et al. A functional genetic variant in microRNA-196a2 is associated with increased susceptibility of lung cancer in Chinese. Cancer Epidemiol Biomarkers Prev. 2009; 18: 1183-1187.
63. Jazdzewski K, Murray EL, Franssila K, et al. Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma. Proc Natl Acad Sci U S A. 2008; 105: 7269-7274. (Pubitemid 351754467)
64. Xu T, Zhu Y, Wei QK, et al. A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma. Carcinogenesis. 2008; 29: 2126-2131.
65. Lu J, Getz G, Miska EA, et al. MicroRNA expression profiles classify human cancers. Nature. 2005; 435: 834-838. (Pubitemid 40839735)
66. Michael MZ, SM OC, van Holst Pellekaan NG, et al. Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol Cancer Res. 2003; 1: 882-891. (Pubitemid 37288707)
67. Schetter AJ, Leung SY, Sohn JJ, et al. MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA. 2008; 299: 425-436. (Pubitemid 351185951)
68. Schepeler T, Reinert JT, Ostenfeld MS, et al. Diagnostic and prognostic microRNAs in stage II colon cancer. Cancer Res. 2008; 68: 6416-6424.
69. Xi Y, Shalgi R, Fodstad O, et al. Differentially regulated micro-RNAs and actively translated messenger RNA transcripts by tumor suppressor p53 in colon cancer. Clin Cancer Res. 2006; 12: 2014-2024.
70. Johnson SM, Grosshans H, Shingara J, et al. RAS is regulated by the let-7 microRNA family. Cell. 2005; 120: 635-647. (Pubitemid 40343076)
71. O'Donnell KA, Wentzel EA, Zeller KI, et al. c-Myc-regulated microRNAs modulate E2F1 expression. Nature. 2005; 435: 839-843. (Pubitemid 40839736)
72. Untawale S, Blick M,. Oncogene expression in adenocarcinomas of the colon and in colon tumor-derived cell lines. Anticancer Res. 1988; 8: 1-7.
73. Li X, Carthew RW,. A microRNA mediates EGF receptor signaling and promotes photoreceptor differentiation in the Drosophila eye. Cell. 2005; 123: 1267-1277. (Pubitemid 41821784)
74. Hua Z, Lv Q, Ye W, et al. MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia. PLoS One. 2006; 1: e116.
75. Ekbom A, Helmick C, Zack M, et al. Ulcerative colitis and colorectal cancer. A population-based study. N Engl J Med. 1990; 323: 1228-1233. (Pubitemid 20366527)
76. Olaru AV, Selaru FM, Mori Y, et al. Dynamic changes in the expression of MicroRNA-31 during inflammatory bowel disease-associated neoplastic transformation. Inflamm Bowel Dis. 2011; 17: 221-231.