Immune memory and exhaustion: Clinically relevant lessons from the LCMV model

Advances in Experimental Medicine and Biology

Volumn 850, Issue , 2015, Pages 137-152

  Zehn, D ^a   Wherry, E J ^b  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b Department of Molecular Virology Immunology   (United States)

Author keywords

Infections; Lymphocytic choriomeningitis virus (LCMV); Memory CD8 T cells; T cell exhaustion; Translational research

Indexed keywords

PROGRAMMED DEATH 1 RECEPTOR; TRANSCRIPTION FACTOR T BET; INTERLEUKIN 15; INTERLEUKIN 7; INTERLEUKIN-7, MOUSE; PDCD1 PROTEIN, MOUSE;

ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; HUMAN; IMMUNOLOGICAL MEMORY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC CHORIOMENINGITIS; MEMORY T LYMPHOCYTE; NONHUMAN; PERSISTENT VIRUS INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; T CELL EXHAUSTION; T LYMPHOCYTE SUBPOPULATION; TRANSCRIPTION REGULATION; TRANSLATIONAL RESEARCH; ANIMAL; CLONAL ANERGY; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MOUSE; PATHOLOGY; VIROLOGY; VIRUS LOAD;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CLONAL ANERGY; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMANS; IMMUNOLOGIC MEMORY; INTERLEUKIN-15; INTERLEUKIN-7; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; PROGRAMMED CELL DEATH 1 RECEPTOR; TRANSLATIONAL MEDICAL RESEARCH; VIRAL LOAD;

EID: 84940845146     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-3-319-15774-0_10     Document Type: Article

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