Neuroprotective effects of alpha-mangostin on MPP+-induced apoptotic cell death in neuroblastoma SH-SY5Y cells

Journal of Toxicology

Volumn 2015, Issue , 2015, Pages

  Janhom, Prachya ^a   Dharmasaroja, Permphan ^a  

^a Mahidol University ^*  (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA MANGOSTIN; CASPASE 3; CELL NUCLEUS DNA; NEUROPROTECTIVE AGENT; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY ASSAY; COCULTURE; CONTROLLED STUDY; DRUG MECHANISM; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MORPHOLOGY; NEUROBLASTOMA CELL; NEUROPROTECTION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 84940765830     PISSN: 16878191     EISSN: 16878205     Source Type: Journal    
DOI: 10.1155/2015/919058     Document Type: Article

References (49)

1. M. P. Mattson, "Apoptosis in neurodegenerative disorders," Nature Reviews Molecular Cell Biology, vol. 1, no. 2, pp. 120-129, 2000.
2. P. A. Ballard, J. W. Tetrud, and J. W. Langston, "Permanent human parkinsonism due to 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP): seven cases," Neurology, vol. 35, no. 7, pp. 949-956, 1985.
3. J. W. Langston, I. Irwin, E. B. Langston, and L. S. Forno, "1-Methyl-4-phenylpyridinium ion (MPP+): identification of a metabolite of MPTP, a toxin selective to the substantia nigra," Neuroscience Letters, vol. 48, no. 1, pp. 87-92, 1984.
4. T. P. Singer and R. R. Ramsay, "Mechanism of the neurotoxicity of MPTP. An update," FEBS Letters, vol. 274, no. 1-2, pp. 1-8, 1990.
5. S. Przedborski and V. Jackson-Lewis, "Mechanisms of MPTP toxicity," Movement Disorders, vol. 13, no. 1, pp. 35-38, 1998.
6. T. A. Seaton, J. M. Cooper, and A. H. V. Schapira, "Cyclosporin inhibition of apoptosis induced by mitochondrial complex I toxins," Brain Research, vol. 809, no. 1, pp. 12-17, 1998.
7. K. Suzuki, Y. Mizuno, and M. Yoshida, "Effects of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-like compounds on mitochondrial respiration. ," Advances in neurology, vol. 53, pp. 215-218, 1990.
8. R. J. Smeyne and V. Jackson-Lewis, "The MPTP model of Parkinsons disease," Molecular Brain Research, vol. 134, no. 1, pp. 57-66, 2005.
9. G. Zeng, T. Tang, H.-J. Wu et al., "Salvianolic acid b protects SHSY5Y neuroblastoma cells from1-methyl-4-phenylpyridiniuminduced apoptosis," Biological & Pharmaceutical Bulletin, vol. 33, no. 8, pp. 1337-1342, 2010.
10. S. V. Kalivendi, S. Kotamraju, S. Cunningham, T. Shang, C. J. Hillard, and B. Kalyanaraman, "1-Methyl-4-phenylpyridinium (MPP+)-induced apoptosis and mitochondrial oxidant generation: role of transferrin-receptor-dependent iron and hydrogen peroxide," Biochemical Journal, vol. 371, part 1, pp. 151-164, 2003.
11. D. Blum, S. Torch, N. Lambeng et al., "Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinsons disease," Progress in Neurobiology, vol. 65, no. 2, pp. 135-172, 2001.
12. J. Yang, X. Liu, K. Bhalla et al., "Prevention of apoptosis by Bcl-2: release of cytochrome c frommitochondria blocked," Science, vol. 275, no. 5303, pp. 1129-1132, 1997.
13. H. Turmel, A. Hartmann, K. Parain et al., "Caspase-3 activation in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-treated mice," Movement Disorders, vol. 16, no. 2, pp. 185-189, 2001.
14. Q. Xu, A. G. Kanthasamy, and M. B. Reddy, "Neuroprotective effect of the natural iron chelator, phytic acid in a cell culture model of Parkinsons disease," Toxicology, vol. 245, no. 1-2, pp. 101-108, 2008.
15. D.-S. Sun and H.-H. Chang, "Differential regulation of JNK in caspase-3-mediated apoptosis of MPP+-treated primary cortical neurons," Cell Biology International, vol. 27, no. 9, pp. 769-777, 2003.
16. J.-H. Cheng, A.-M. Huang, T.-C. Hour, S.-C. Yang, Y.-S. Pu, and C.-N. Lin, "Antioxidant xanthone derivatives induce cell cycle arrest and apoptosis and enhance cell death induced by cisplatin in NTUB1 cells associated with ROS," European Journal of Medicinal Chemistry, vol. 46, no. 4, pp. 1222-1231, 2011.
17. Y. Zhao, J.-P. Liu, D. Lu, P.-Y. Li, and L.-X. Zhang, "A new antioxidant xanthone from the pericarp ofGarcinia mangostana Linn. ," Natural Product Research, vol. 24, no. 17, pp. 1664-1670, 2010.
18. M. Kondo, L. Zhang, H. Ji, Y. Kou, and B. Ou, "Bioavailability and antioxidant effects of a xanthone-rich mangosteen (Garcinia mangostana) product in humans," Journal of Agricultural and Food Chemistry, vol. 57, no. 19, pp. 8788-8792, 2009.
19. M. Buelna-Chontal, F. Correa, S. Hernández-Reséndiz, C. Zazueta, and J. Pedraza-Chaverri, "Protective effect of alphamangostin on cardiac reperfusion damage by attenuation of oxidative stress," Journal of Medicinal Food, vol. 14, no. 11, pp. 1370-1374, 2011.
20. W. Weecharangsan, P. Opanasopit, M. Sukma, T. Ngawhirunpat, U. Sotanaphun, and P. Siripong, "Antioxidative and neuroprotective activities of extracts from the fruit hull of mangosteen (Garcinia mangostana Linn. )," Medical Principles and Practice, vol. 15, no. 4, pp. 281-287, 2006.
21. L. M. Reyes-Fermín, S. González-Reyes, N. G. Tarco-Álvarez, M. Hernández-Nava, M. Orozco-Ibarra, and J. Pedraza-Chaverri, "Neuroprotective effect of α-mangostin and curcumin against iodoacetate-induced cell death," Nutritional Neuroscience, vol. 15, no. 5, pp. 34-41, 2012.
22. P. Moongkarndi, C. Srisawat, P. Saetun et al., "Protective effect of mangosteen extract against β-amyloid-induced cytotoxicity, oxidative stress and altered proteome in SK-N-SH cells," Journal of Proteome Research, vol. 9, no. 5, pp. 2076-2086, 2010.
23. Y. Wang, Z. Xia, J.-R. Xu et al., "α-mangostin, a polyphenolic xanthone derivative from mangosteen, attenuates β-amyloid oligomers-induced neurotoxicity by inhibiting amyloid aggregation," Neuropharmacology, vol. 62, no. 2, pp. 871-881, 2012.
24. B. Márquez-Valadez, P. D. Maldonado, S. Galván-Arzate et al., "Alpha-mangostin induces changes in glutathione levels associated with glutathione peroxidase activity in rat brain synaptosomes," Nutritional Neuroscience, vol. 15, no. 5, pp. 13-19, 2012.
25. D. S. Cassarino, C. P. Fall, R. H. Swerdlow et al., "Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinsons disease," Biochimica et Biophysica Acta, vol. 1362, no. 1, pp. 77-86, 1997.
26. C. P. Fall and J. P. Bennett Jr., "Characterization and time course of MPP+ -induced apoptosis in human SH-SY5Y neuroblastoma cells," Journal of Neuroscience Research, vol. 55, no. 5, pp. 620-628, 1999.
27. E. Hasegawa, D. Kang, K. Sakamoto et al., "A dual effect of 1-methyl-4-phenylpyridinium (MPP+)-analogs on the respiratory chain of bovine heart mitochondria," Archives of Biochemistry and Biophysics, vol. 337, no. 1, pp. 69-74, 1997.
28. M. Lai, H. Griffiths, H. Pall, A. Williams, and J. Lunec, "An investigation into the role of reactive oxygen species in the mechanism of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine toxicity using neuronal cell lines," Biochemical Pharmacology, vol. 45, no. 4, pp. 927-933, 1993.
29. Y. Akaneya, M. Takahashi, and H. Hatanaka, "Involvement of free radicals in MPP+ neurotoxicity against rat dopaminergic neurons in culture," Neuroscience Letters, vol. 193, no. 1, pp. 53-56, 1995.
30. J. Pedraza-Chaverri, N. Cárdenas-Rodríguez, M. Orozco-Ibarra, and J. M. Pérez-Rojas, "Medicinal properties of mangosteen (Garciniamangostana)," Food and Chemical Toxicology, vol. 46, no. 10, pp. 3227-3239, 2008.
31. K. M. Robinson, M. S. Janes, M. Pehar et al., "Selective fluorescent imaging of superoxide in vivo using ethidium-based probes," Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 41, pp. 15038-15043, 2006.
32. A. Gomes, E. Fernandes, and J. L. F. C. Lima, "Fluorescence probes used for detection of reactive oxygen species," Journal of Biochemical and Biophysical Methods, vol. 65, no. 2-3, pp. 45-80, 2005.
33. H.-A. Jung, B.-N. Su, W. J. Keller, R. G. Mehta, and A. D. Kinghorn, "Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen)," Journal of Agricultural and Food Chemistry, vol. 54, no. 6, pp. 2077-2082, 2006.
34. J. Alexandre, F. Batteux, C. Nicco et al., "Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo," International Journal of Cancer, vol. 119, no. 1, pp. 41-48, 2006.
35. B. S. Rayner, T. T. H. Duong, S. J. Myers, and P. K. Witting, Protective effect of a synthetic anti-oxidant on neuronal cell apoptosis resulting from experimental hypoxia re-oxygenation injury," Journal of Neurochemistry, vol. 97, no. 1, pp. 211-221, 2006.
36. M. Higuchi, T. Honda, R. J. Proske, and E. T. H. Yeh, "Regulation of reactive oxygen species-induced apoptosis and necrosis by caspase 3-like proteases," Oncogene, vol. 17, no. 21, pp. 2753-2760, 1998.
37. W. Suwanjang, A. Y. Abramov, P. Govitrapong, and B. Chetsawang, "Melatonin attenuates dexamethasone toxicityinduced oxidative stress, calpain and caspase activation in human neuroblastoma SH-SY5Y cells," Journal of Steroid Biochemistry and Molecular Biology, vol. 138, pp. 116-122, 2013.
38. D. A. Hildeman, T. Mitchell, B. Aronowt, S. Wojciechowski, J. Kappler, and P. Marrack, "Control of Bcl-2 expression by reactive oxygen species," Proceedings of the National Academy of Sciences of the United States of America, vol. 100, no. 25, pp. 15035-15040, 2003.
39. Y. Sánchez-Pérez, R. Morales-Bárcenas, C. M. García-Cuellar et al., "The α-mangostin prevention on cisplatin-induced apoptotic death in LLC-PK1 cells is associated to an inhibition of ROS production and p53 induction," Chemico-Biological Interactions, vol. 188, no. 1, pp. 144-150, 2010.
40. M. T. Hemann and S. W. Lowe, "The p53-Bcl-2 connection," Cell Death & Differentiation, vol. 13, no. 8, pp. 1256-1259, 2006.
41. S. A. Lakhani, A. Masud, K. Kuida et al., "Caspases 3 and 7: key mediators of mitochondrial events of apoptosis," Science, vol. 311, no. 5762, pp. 847-851, 2006.
42. D. Mandal, P. K. Moitra, S. Saha, and J. Basu, "Caspase 3 regulates phosphatidylserine externalization and phagocytosis of oxidatively stressed erythrocytes," FEBS Letters, vol. 513, no. 2-3, pp. 184-188, 2002.
43. S.-H. Lee, X. W. Meng, K. S. Flatten, D. A. Loegering, and S. H. Kaufmann, "Phosphatidylserine exposure during apoptosis reflects bidirectional trafficking between plasmamembrane and cytoplasm," Cell Death & Differentiation, vol. 20, no. 1, pp. 64-76, 2013.
44. J. M. Pérez-Rojas, C. Cruz, P. García-López et al., "Renoprotection by alpha-Mangostin is related to the attenuation in renal oxidative/nitrosative stress induced by cisplatin nephrotoxicity," Free Radical Research, vol. 43, no. 11, pp. 1122-1132, 2009.
45. L.-G. Chen, L.-L. Yang, and C.-C. Wang, "Anti-inflammatory activity of mangostins from Garcinia mangostana," Food and Chemical Toxicology, vol. 46, no. 2, pp. 688-693, 2008.
46. S. Tewtrakul, C. Wattanapiromsakul, and W. Mahabusarakam, Effects of compounds from Garcinia mangostana on inflammatory mediators in RAW264. 7 macrophage cells," Journal of Ethnopharmacology, vol. 121, no. 3, pp. 379-382, 2009.
47. N. Chairungsrilerd, K.-I. Furukawa, T. Ohta, S. Nozoe, and Y. Ohizumi, "Pharmacological properties of α-mangostin, a novel histamine H1 receptor antagonist," European Journal of Pharmacology, vol. 314, no. 3, pp. 351-356, 1996.
48. P. D. Sampath and K. Vijayaraghavan, "Cardioprotective effect of α-mangostin, a xanthone derivative from Mangosteen on tissue defense system against isoproterenol-inducedmyocardial infarction in rats," Journal of Biochemical and Molecular Toxicology, vol. 21, no. 6, pp. 336-339, 2007.
49. A. Navya, D. J. Rayalu, and P. U. Maheswari Devi, "Docking studies on xanthones of mangosteen as cox-2 inhibitors," International Journal of Applied Biology and Pharmaceutical Technology, vol. 2, no. 31, pp. 263-268, 2011.