Impact assessment of cigarette smoke exposure on organotypic bronchial epithelial tissue cultures: A comparison of mono-culture and coculture model containing fibroblasts

Toxicological Sciences

Volumn 147, Issue 1, 2015, Pages 207-221

  Iskandar, Anita R ^a   Xiang, Yang ^a   Frentzel, Stefan ^a   Talikka, Marja ^a   Leroy, Patrice ^a   Kuehn, Diana ^a   Guedj, Emmanuel ^a   Martin, Florian ^a   Mathis, Carole ^a   Ivanov, Nikolai V ^a   Peitsch, Manuel C ^a   Hoeng, Julia ^a  

^a PHILIP MORRIS PRODUCTS S A   (Switzerland)

Author keywords

Aerosol; Air liquid interface; Biological network; Coculture; Transcriptomic

Indexed keywords

ADENYLATE KINASE; CIGARETTE SMOKE; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; CYTOCHROME P450; SMOKE;

ADULT; AEROSOL; ARTICLE; BRONCHUS MUCOSA; CELL STRESS; COCULTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; EPITHELIUM CELL; FEMALE; FIBROBLAST; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INTERMETHOD COMPARISON; MEDIATOR; MIDDLE AGED; MONOCULTURE; TISSUE CULTURE TECHNIQUE; TISSUE INJURY; TOXICOLOGY; XENOBIOTIC METABOLISM; ADVERSE EFFECTS; BRONCHUS; COMPARATIVE STUDY; DRUG EFFECTS; GENE EXPRESSION; METABOLISM; PATHOLOGY; RESPIRATORY MUCOSA; SMOKE; TOBACCO; TOXICITY;

ADENYLATE KINASE; BRONCHI; COCULTURE TECHNIQUES; CYTOCHROME P-450 ENZYME SYSTEM; EPITHELIAL CELLS; FIBROBLASTS; GENE EXPRESSION; HUMANS; RESPIRATORY MUCOSA; SMOKE; TISSUE CULTURE TECHNIQUES; TOBACCO; TOBACCO PRODUCTS;

EID: 84940643578     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfv122     Document Type: Article

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