Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol

Nature

Volumn 524, Issue 7566, 2015, Pages 485-488

  Wrobel, Lidia ^a   Topf, Ulrike ^a   Bragoszewski, Piotr ^a   Wiese, Sebastian ^b,e   Sztolsztener, Malgorzata E ^a   Oeljeklaus, Silke ^b   Varabyova, Aksana ^a   Lirski, Maciej ^c   Chroscicki, Piotr ^a   Mroczek, Seweryn ^c,d   Januszewicz, Elzbieta ^a   Dziembowski, Andrzej ^c,d   Koblowska, Marta ^c,d   Warscheid, Bettina ^b   Chacinska, Agnieszka ^a  

^a INTERNATIONAL INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Poland)

^b UNIVERSITY OF FREIBURG   (Germany)

^c INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^d UNIVERSITY OF WARSAW   (Poland)

^e UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; MITOCHONDRIAL PROTEIN; PROTEIN PRECURSOR; PROTEOME; TRANSCRIPTOME; PROTEASOME; SACCHAROMYCES CEREVISIAE PROTEIN;

CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; MITOCHONDRION; PATHOLOGY; PHYSIOLOGY; PROTEIN; PROTEOMICS;

ANIMAL CELL; ARTICLE; BIOGENESIS; CELL ACTIVATION; CELL FRACTIONATION; CELL ORGANELLE; CELL PROTECTION; CELL STRESS; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL TARGETING SIGNAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN HOMEOSTASIS; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; UNFOLDED PROTEIN RESPONSE; CYTOLOGY; GENETICS; METABOLISM; MITOCHONDRION; PATHOLOGY; PHYSIOLOGICAL STRESS; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE;

CYTOSOL; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BIOSYNTHESIS; PROTEIN PRECURSORS; PROTEIN TRANSPORT; PROTEOME; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; STRESS, PHYSIOLOGICAL; TRANSCRIPTOME; UNFOLDED PROTEIN RESPONSE;

EID: 84940556804     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14951     Document Type: Article

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