20S Proteasome Assembly Is Orchestrated by Two Distinct Pairs of Chaperones in Yeast and in Mammals

Molecular Cell

Volumn 27, Issue 4, 2007, Pages 660-674

  Le Tallec, Benoît ^a   Barrault, Marie Bénédicte ^a   Courbeyrette, Régis ^a   Guérois, Raphaël ^a   Marsolier Kergoat, Marie Claude ^a   Peyroche, Anne ^a  

^a SERVICE DE CHIMIE BIOORGANIQUE ET DE MARQUAGE   (France)

Author keywords

PROTEINS

Indexed keywords

CHAPERONE; PROTEASOME;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; EVOLUTION; MAMMAL; NONHUMAN; PHENOTYPE; YEAST;

ANIMALS; CELL LINE; DIMERIZATION; DNA DAMAGE; EPISTASIS, GENETIC; GENES, FUNGAL; HUMANS; MAMMALS; MOLECULAR CHAPERONES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN PRECURSORS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

MAMMALIA;

EID: 34547838178     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2007.06.025     Document Type: Article

References (36)

1. Arendt C.S., and Hochstrasser M. Identification of the yeast 20S proteasome catalytic centers and subunit interactions required for active-site formation. Proc. Natl. Acad. Sci. USA 94 (1997) 7156-7161
2. Baumeister W., Walz J., Zuhl F., and Seemuller E. The proteasome: paradigm of a self-compartmentalizing protease. Cell 92 (1998) 367-380
3. Becker E., Meyer V., Madaoui H., and Guerois R. Detection of a tandem BRCT in Nbs1 and Xrs2 with functional implications in the DNA damage response. Bioinformatics 22 (2006) 1289-1292
4. Burri L., Hockendorff J., Boehm U., Klamp T., Dohmen R.J., and Levy F. Identification and characterization of a mammalian protein interacting with 20S proteasome precursors. Proc. Natl. Acad. Sci. USA 97 (2000) 10348-10353
5. Chen P., and Hochstrasser M. Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assembly. Cell 86 (1996) 961-972
6. Dohmen R.J., London M.K., Glanemann C., and Ramos P.C. Assays for proteasome assembly and maturation. Methods Mol. Biol. 301 (2005) 243-254
7. Frentzel S., Pesold-Hurt B., Seelig A., and Kloetzel P.M. 20 S proteasomes are assembled via distinct precursor complexes. Processing of LMP2 and LMP7 proproteins takes place in 13-16 S preproteasome complexes. J. Mol. Biol. 236 (1994) 975-981
8. Glickman M.H., and Ciechanover A. The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol. Rev. 82 (2002) 373-428
9. Griffin T.A., Slack J.P., McCluskey T.S., Monaco J.J., and Colbert R.A. Identification of proteassemblin, a mammalian homologue of the yeast protein, Ump1p, that is required for normal proteasome assembly. Mol. Cell Biol. Res. Commun. 3 (2000) 212-217
10. Groll M., Bochtler M., Brandstetter H., Clausen T., and Huber R. Molecular machines for protein degradation. ChemBioChem 6 (2005) 222-256
11. Heinemeyer W., Fischer M., Krimmer T., Stachon U., and Wolf D.H. The active sites of the eukaryotic 20 S proteasome and their involvement in subunit precursor processing. J. Biol. Chem. 272 (1997) 25200-25209
12. Hirano Y., Hendil K.B., Yashiroda H., Iemura S., Nagane R., Hioki Y., Natsume T., Tanaka K., and Murata S. A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes. Nature 437 (2005) 1381-1385
13. Hirano Y., Hayashi H., Iemura S., Hendil K.B., Niwa S., Kishimoto T., Kasahara M., Natsume T., Tanaka K., and Murata S. Cooperation of multiple chaperones required for the assembly of mammalian 20S proteasomes. Mol. Cell 24 (2006) 977-984
14. Isono E., Nishihara K., Saeki Y., Yashiroda H., Kamata N., Ge L., Ueda T., Kikuchi Y., Tanaka K., Nakano A., and Toh E.A. The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome. Mol. Biol. Cell 18 (2007) 569-580
15. Laney J.D., and Hochstrasser M. Assaying protein ubiquitination in Saccharomyces cerevisiae. Methods Enzymol. 351 (2002) 248-257
16. Lehmann A., Janek K., Braun B., Kloetzel P.M., and Enenkel C. 20 S proteasomes are imported as precursor complexes into the nucleus of yeast. J. Mol. Biol. 317 (2002) 401-413
17. Li X., Kusmierczyk A.R., Wong P., Emili A., and Hochstrasser M. beta-Subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpoint. EMBO J. 26 (2007) 2339-2349
18. London M.K., Keck B.I., Ramos P.C., and Dohmen R.J. Regulatory mechanisms controlling biogenesis of ubiquitin and the proteasome. FEBS Lett. 567 (2004) 259-264
19. Marsolier M.C., Roussel P., Leroy C., and Mann C. Involvement of the PP2C-like phosphatase Ptc2p in the DNA checkpoint pathways of Saccharomyces cerevisiae. Genetics 154 (2000) 1523-1532
20. Melo J., and Toczyski D. A unified view of the DNA-damage checkpoint. Curr. Opin. Cell Biol. 14 (2002) 237-245
21. Murata S. Multiple chaperone-assisted formation of mammalian 20S proteasomes. IUBMB Life 58 (2006) 344-348
22. Nandi D., Woodward E., Ginsburg D.B., and Monaco J.J. Intermediates in the formation of mouse 20S proteasomes: implications for the assembly of precursor beta subunits. EMBO J. 16 (1997) 5363-5375
23. Pan X., Ye P., Yuan D.S., Wang X., Bader J.S., and Boeke J.D. A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124 (2006) 1069-1081
24. Ramos P.C., Hockendorff J., Johnson E.S., Varshavsky A., and Dohmen R.J. Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly. Cell 92 (1998) 489-499
25. Ramos P.C., Marques A.J., London M.K., and Dohmen R.J. Role of C-terminal extensions of subunits beta2 and beta7 in assembly and activity of eukaryotic proteasomes. J. Biol. Chem. 279 (2004) 14323-14330
26. Schmidtke G., Kraft R., Kostka S., Henklein P., Frommel C., Lowe J., Huber R., Kloetzel P.M., and Schmidt M. Analysis of mammalian 20S proteasome biogenesis: the maturation of beta-subunits is an ordered two-step mechanism involving autocatalysis. EMBO J. 15 (1996) 6887-6898
27. Schmidtke G., Schmidt M., and Kloetzel P.M. Maturation of mammalian 20 S proteasome: purification and characterization of 13 S and 16 S proteasome precursor complexes. J. Mol. Biol. 268 (1997) 95-106
28. Seemuller E., Lupas A., and Baumeister W. Autocatalytic processing of the 20S proteasome. Nature 382 (1996) 468-471
29. Tone Y., and Toh E.A. Nob1p is required for biogenesis of the 26S proteasome and degraded upon its maturation in Saccharomyces cerevisiae. Genes Dev. 16 (2002) 3142-3157
30. Velichutina I., Connerly P.L., Arendt C.S., Li X., and Hochstrasser M. Plasticity in eucaryotic 20S proteasome ring assembly revealed by a subunit deletion in yeast. EMBO J. 23 (2004) 500-510
31. Witt E., Zantopf D., Schmidt M., Kraft R., Kloetzel P.M., and Kruger E. Characterisation of the newly identified human Ump1 homologue POMP and analysis of LMP7(beta 5i) incorporation into 20 S proteasomes. J. Mol. Biol. 301 (2000) 1-9
32. Witt S., Kwon Y.D., Sharon M., Felderer K., Beuttler M., Robinson C.V., Baumeister W., and Jap B.K. Proteasome assembly triggers a switch required for active-site maturation. Structure 14 (2006) 1179-1188
33. Wolf D.H., and Hilt W. The proteasome: a proteolytic nanomachine of cell regulation and waste disposal. Biochim. Biophys. Acta 1695 (2004) 19-31
34. Xie Y., and Varshavsky A. RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuit. Proc. Natl. Acad. Sci. USA 98 (2001) 3056-3061
35. Zhou B.B., and Elledge S.J. The DNA damage response: putting checkpoints in perspective. Nature 408 (2000) 433-439
36. Zwickl P., Kleinz J., and Baumeister W. Critical elements in proteasome assembly. Nat. Struct. Biol. 1 (1994) 765-770