-
1
-
-
84873252557
-
Liposomal drug delivery systems: from concept to clinical applications
-
Allen T.M., Cullis P.R. Liposomal drug delivery systems: from concept to clinical applications. Adv. Drug Deliv. Rev. 2013, 65:36-48.
-
(2013)
Adv. Drug Deliv. Rev.
, vol.65
, pp. 36-48
-
-
Allen, T.M.1
Cullis, P.R.2
-
2
-
-
0035795022
-
PEGylated PLGA nanoparticles as protein carriers: synthesis, preparation and biodistribution in rats
-
Li Y-P., et al. PEGylated PLGA nanoparticles as protein carriers: synthesis, preparation and biodistribution in rats. J. Control. Release 2001, 71:203-211.
-
(2001)
J. Control. Release
, vol.71
, pp. 203-211
-
-
Li, Y.-P.1
-
3
-
-
84901339386
-
Penetrating the cell membrane, thermal targeting and novel anticancer drugs: the development of thermally targeted, elastin-like polypeptide cancer therapeutics
-
Ryu J.S., et al. Penetrating the cell membrane, thermal targeting and novel anticancer drugs: the development of thermally targeted, elastin-like polypeptide cancer therapeutics. Ther. Deliv. 2014, 5:429-445.
-
(2014)
Ther. Deliv.
, vol.5
, pp. 429-445
-
-
Ryu, J.S.1
-
4
-
-
84898542045
-
Cell-penetrating peptides: A tool for effective delivery in gene-targeted therapies
-
Figueiredo I.R., et al. Cell-penetrating peptides: A tool for effective delivery in gene-targeted therapies. IUBMB Life 2014, 66:182-194.
-
(2014)
IUBMB Life
, vol.66
, pp. 182-194
-
-
Figueiredo, I.R.1
-
5
-
-
77952231544
-
Cell-penetrating peptides and their therapeutic applications
-
Sebbage V. Cell-penetrating peptides and their therapeutic applications. Biosci. Horizons 2009, 2:64-72.
-
(2009)
Biosci. Horizons
, vol.2
, pp. 64-72
-
-
Sebbage, V.1
-
6
-
-
84878628958
-
Cell-penetrating peptide enhanced intracellular Raman imaging and photodynamic therapy
-
Fales A.M., et al. Cell-penetrating peptide enhanced intracellular Raman imaging and photodynamic therapy. Mol. Pharm. 2013, 10:2291-2298.
-
(2013)
Mol. Pharm.
, vol.10
, pp. 2291-2298
-
-
Fales, A.M.1
-
7
-
-
70349759756
-
Conjugation of doxorubicin to cell penetrating peptides sensitizes human breast MDA-MB 231 cancer cells to endogenous TRAIL-induced apoptosis
-
Aroui S., et al. Conjugation of doxorubicin to cell penetrating peptides sensitizes human breast MDA-MB 231 cancer cells to endogenous TRAIL-induced apoptosis. Apoptosis 2009, 14:1352-1365.
-
(2009)
Apoptosis
, vol.14
, pp. 1352-1365
-
-
Aroui, S.1
-
8
-
-
0024262589
-
Cellular uptake of the tat protein from human immunodeficiency virus
-
Frankel A.D., Pabo C.O. Cellular uptake of the tat protein from human immunodeficiency virus. Cell 1988, 55:1189-1193.
-
(1988)
Cell
, vol.55
, pp. 1189-1193
-
-
Frankel, A.D.1
Pabo, C.O.2
-
9
-
-
65549133368
-
Delivery of macromolecules using arginine-rich cell-penetrating peptides: ways to overcome endosomal entrapment
-
El-Sayed A., et al. Delivery of macromolecules using arginine-rich cell-penetrating peptides: ways to overcome endosomal entrapment. AAPS J. 2009, 11:13-22.
-
(2009)
AAPS J.
, vol.11
, pp. 13-22
-
-
El-Sayed, A.1
-
10
-
-
84866535298
-
Applications of cell-penetrating peptides for tumor targeting and future cancer therapies
-
Regberg J., et al. Applications of cell-penetrating peptides for tumor targeting and future cancer therapies. Pharmaceuticals (Basel) 2012, 5:991-1007.
-
(2012)
Pharmaceuticals (Basel)
, vol.5
, pp. 991-1007
-
-
Regberg, J.1
-
11
-
-
0031423050
-
Cellular delivery of oligonucleotides by synthetic import peptide carrier
-
Dokka S., et al. Cellular delivery of oligonucleotides by synthetic import peptide carrier. Pharm. Res. 1997, 14:1759-1764.
-
(1997)
Pharm. Res.
, vol.14
, pp. 1759-1764
-
-
Dokka, S.1
-
12
-
-
79960425133
-
Fibroblast growth factor-12 (FGF12) translocation into intestinal epithelial cells is dependent on a novel cell-penetrating peptide domain: involvement of internalization in the in vivo role of exogenous FGF12
-
Nakayama F., et al. Fibroblast growth factor-12 (FGF12) translocation into intestinal epithelial cells is dependent on a novel cell-penetrating peptide domain: involvement of internalization in the in vivo role of exogenous FGF12. J. Biol. Chem. 2011, 286:25823-25834.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 25823-25834
-
-
Nakayama, F.1
-
13
-
-
38949184554
-
Delivery of proteins and nucleic acids using a non-covalent peptide-based strategy
-
Deshayes S., et al. Delivery of proteins and nucleic acids using a non-covalent peptide-based strategy. Adv. Drug Deliv. Rev. 2008, 60:537-547.
-
(2008)
Adv. Drug Deliv. Rev.
, vol.60
, pp. 537-547
-
-
Deshayes, S.1
-
14
-
-
1942435239
-
Amphipathic peptides and drug delivery
-
Fernandez-Carneado J., et al. Amphipathic peptides and drug delivery. Biopolymers 2004, 76:196-203.
-
(2004)
Biopolymers
, vol.76
, pp. 196-203
-
-
Fernandez-Carneado, J.1
-
15
-
-
80053326172
-
RGD targeting hyaluronic acid coating system for PEI-PBLG polycation gene carriers
-
Tian H., et al. RGD targeting hyaluronic acid coating system for PEI-PBLG polycation gene carriers. J. Control. Release 2011, 155:47-53.
-
(2011)
J. Control. Release
, vol.155
, pp. 47-53
-
-
Tian, H.1
-
16
-
-
0032922213
-
Intercellular trafficking of VP22-GFP fusion proteins
-
Elliott G., O'Hare P. Intercellular trafficking of VP22-GFP fusion proteins. Gene Ther. 1999, 6:149-151.
-
(1999)
Gene Ther.
, vol.6
, pp. 149-151
-
-
Elliott, G.1
O'Hare, P.2
-
17
-
-
84888270870
-
Peptides as drugs: from screening to application
-
Dietrich U., et al. Peptides as drugs: from screening to application. Curr. Pharm. Biotechnol. 2013, 14:501-512.
-
(2013)
Curr. Pharm. Biotechnol.
, vol.14
, pp. 501-512
-
-
Dietrich, U.1
-
18
-
-
42049095153
-
Cell-penetrating peptides: from molecular mechanisms to therapeutics
-
Morris M.C., et al. Cell-penetrating peptides: from molecular mechanisms to therapeutics. Biol. Cell 2008, 100:201-217.
-
(2008)
Biol. Cell
, vol.100
, pp. 201-217
-
-
Morris, M.C.1
-
19
-
-
70349456654
-
Recent advances in the use of cell-penetrating peptides for medical and biological applications
-
Fonseca S.B., et al. Recent advances in the use of cell-penetrating peptides for medical and biological applications. Adv. Drug Deliv. Rev. 2009, 61:953-964.
-
(2009)
Adv. Drug Deliv. Rev.
, vol.61
, pp. 953-964
-
-
Fonseca, S.B.1
-
20
-
-
0346460957
-
Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake
-
Richard J.P., et al. Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake. J. Biol. Chem. 2003, 278:585-590.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 585-590
-
-
Richard, J.P.1
-
21
-
-
34548183102
-
Arginine-rich peptides and their internalization mechanisms
-
Futaki S., et al. Arginine-rich peptides and their internalization mechanisms. Biochem. Soc. Trans. 2007, 35:784-787.
-
(2007)
Biochem. Soc. Trans.
, vol.35
, pp. 784-787
-
-
Futaki, S.1
-
22
-
-
34547114456
-
Pathways of clathrin-independent endocytosis
-
Mayor S., Pagano R.E. Pathways of clathrin-independent endocytosis. Nat. Rev. Mol. Cell Biol. 2007, 8:603-612.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 603-612
-
-
Mayor, S.1
Pagano, R.E.2
-
23
-
-
35048856889
-
Cargo-dependent cytotoxicity and delivery efficacy of cell-penetrating peptides: a comparative study
-
El-Andaloussi S., et al. Cargo-dependent cytotoxicity and delivery efficacy of cell-penetrating peptides: a comparative study. Biochem. J. 2007, 407:285-292.
-
(2007)
Biochem. J.
, vol.407
, pp. 285-292
-
-
El-Andaloussi, S.1
-
24
-
-
84881022447
-
Solution NMR studies of cell-penetrating peptides in model membrane systems
-
Maler L. Solution NMR studies of cell-penetrating peptides in model membrane systems. Adv. Drug Deliv. Rev. 2013, 65:1002-1011.
-
(2013)
Adv. Drug Deliv. Rev.
, vol.65
, pp. 1002-1011
-
-
Maler, L.1
-
25
-
-
79952201089
-
Homeoprotein intercellular transfer, the hidden face of cell-penetrating peptides
-
Prochiantz A. Homeoprotein intercellular transfer, the hidden face of cell-penetrating peptides. Methods Mol. Biol. 2011, 683:249-257.
-
(2011)
Methods Mol. Biol.
, vol.683
, pp. 249-257
-
-
Prochiantz, A.1
-
26
-
-
0025787585
-
Isolation, amino acid sequence, and synthesis of dermaseptin, a novel antimicrobial peptide of amphibian skin
-
Mor A., et al. Isolation, amino acid sequence, and synthesis of dermaseptin, a novel antimicrobial peptide of amphibian skin. Biochemistry 1991, 30:8824-8830.
-
(1991)
Biochemistry
, vol.30
, pp. 8824-8830
-
-
Mor, A.1
-
27
-
-
67649130542
-
Antimicrobial peptides: to membranes and beyond
-
Marcos J.F., Gandia M. Antimicrobial peptides: to membranes and beyond. Expert Opin. Drug Discov. 2009, 4:659-671.
-
(2009)
Expert Opin. Drug Discov.
, vol.4
, pp. 659-671
-
-
Marcos, J.F.1
Gandia, M.2
-
28
-
-
0036948138
-
Mode of action of membrane active antimicrobial peptides
-
Shai Y. Mode of action of membrane active antimicrobial peptides. Biopolymers 2002, 66:236-248.
-
(2002)
Biopolymers
, vol.66
, pp. 236-248
-
-
Shai, Y.1
-
29
-
-
0033811166
-
Cellular uptake and spread of the cell-permeable peptide penetratin in adult rat brain
-
Bolton S.J., et al. Cellular uptake and spread of the cell-permeable peptide penetratin in adult rat brain. Eur. J. Neurosci. 2000, 12:2847-2855.
-
(2000)
Eur. J. Neurosci.
, vol.12
, pp. 2847-2855
-
-
Bolton, S.J.1
-
30
-
-
84878947567
-
A cancer specific cell-penetrating peptide, BR2, for the efficient delivery of an scFv into cancer cells
-
Lim K.J., et al. A cancer specific cell-penetrating peptide, BR2, for the efficient delivery of an scFv into cancer cells. PLoS ONE 2013, 8:e66084.
-
(2013)
PLoS ONE
, vol.8
, pp. e66084
-
-
Lim, K.J.1
-
31
-
-
84859439673
-
Peptides for cell-selective drug delivery
-
Svensen N., et al. Peptides for cell-selective drug delivery. Trends Pharmacol. Sci. 2012, 33:186-192.
-
(2012)
Trends Pharmacol. Sci.
, vol.33
, pp. 186-192
-
-
Svensen, N.1
-
32
-
-
77949762340
-
Targeting of drugs and nanoparticles to tumors
-
Ruoslahti E., et al. Targeting of drugs and nanoparticles to tumors. J. Cell Biol. 2010, 188:759-768.
-
(2010)
J. Cell Biol.
, vol.188
, pp. 759-768
-
-
Ruoslahti, E.1
-
33
-
-
33645751057
-
Selective inhibition of ErbB2-overexpressing breast cancer in vivo by a novel TAT-based ErbB2-targeting signal transducers and activators of transcription 3-blocking peptide
-
Tan M., et al. Selective inhibition of ErbB2-overexpressing breast cancer in vivo by a novel TAT-based ErbB2-targeting signal transducers and activators of transcription 3-blocking peptide. Cancer Res. 2006, 66:3764-3772.
-
(2006)
Cancer Res.
, vol.66
, pp. 3764-3772
-
-
Tan, M.1
-
34
-
-
33947362046
-
The folate receptor: what does it promise in tissue-targeted therapeutics?
-
Salazar M.D.A., Ratnam M. The folate receptor: what does it promise in tissue-targeted therapeutics?. Cancer Metastasis Rev. 2007, 26:141-152.
-
(2007)
Cancer Metastasis Rev.
, vol.26
, pp. 141-152
-
-
Salazar, M.D.A.1
Ratnam, M.2
-
35
-
-
0141715047
-
Integrin targeting using RGD-PEI conjugates for in vitro gene transfer
-
Kunath K., et al. Integrin targeting using RGD-PEI conjugates for in vitro gene transfer. J. Gene Med. 2003, 5:588-599.
-
(2003)
J. Gene Med.
, vol.5
, pp. 588-599
-
-
Kunath, K.1
-
36
-
-
84860380857
-
CD44 antibody-targeted liposomal nanoparticles for molecular imaging and therapy of hepatocellular carcinoma
-
Wang L., et al. CD44 antibody-targeted liposomal nanoparticles for molecular imaging and therapy of hepatocellular carcinoma. Biomaterials 2012, 33:5107-5114.
-
(2012)
Biomaterials
, vol.33
, pp. 5107-5114
-
-
Wang, L.1
-
37
-
-
0036416110
-
Therapeutic cancer targeting peptides
-
Aina O.H., et al. Therapeutic cancer targeting peptides. Peptide Sci. 2002, 66:184-199.
-
(2002)
Peptide Sci.
, vol.66
, pp. 184-199
-
-
Aina, O.H.1
-
38
-
-
67349230238
-
Cellular siRNA delivery using cell-penetrating peptides modified for endosomal escape
-
Endoh T., Ohtsuki T. Cellular siRNA delivery using cell-penetrating peptides modified for endosomal escape. Adv. Drug Deliv. Rev. 2009, 61:704-709.
-
(2009)
Adv. Drug Deliv. Rev.
, vol.61
, pp. 704-709
-
-
Endoh, T.1
Ohtsuki, T.2
-
39
-
-
84856544910
-
A thermally responsive biopolymer conjugated to an acid-sensitive derivative of paclitaxel stabilizes microtubules, arrests cell cycle, and induces apoptosis
-
Moktan S., et al. A thermally responsive biopolymer conjugated to an acid-sensitive derivative of paclitaxel stabilizes microtubules, arrests cell cycle, and induces apoptosis. Invest. New Drugs 2012, 30:236-248.
-
(2012)
Invest. New Drugs
, vol.30
, pp. 236-248
-
-
Moktan, S.1
-
40
-
-
0141955920
-
Evaluation of an elastin-like polypeptide-doxorubicin conjugate for cancer therapy
-
Dreher M.R., et al. Evaluation of an elastin-like polypeptide-doxorubicin conjugate for cancer therapy. J. Control. Release 2003, 91:31-43.
-
(2003)
J. Control. Release
, vol.91
, pp. 31-43
-
-
Dreher, M.R.1
-
41
-
-
84855772787
-
Cleavable linkers in chemical biology
-
Leriche G., et al. Cleavable linkers in chemical biology. Bioorg. Med. Chem. 2012, 20:571-582.
-
(2012)
Bioorg. Med. Chem.
, vol.20
, pp. 571-582
-
-
Leriche, G.1
-
42
-
-
84900758830
-
A proapoptotic peptide conjugated to penetratin selectively inhibits tumor cell growth
-
Alves I.D., et al. A proapoptotic peptide conjugated to penetratin selectively inhibits tumor cell growth. Biochim. Biophys. Acta Biomembranes 2014, 1838:2087-2098.
-
(2014)
Biochim. Biophys. Acta Biomembranes
, vol.1838
, pp. 2087-2098
-
-
Alves, I.D.1
-
43
-
-
84864572139
-
Protease-activated drug development
-
Choi K.Y., et al. Protease-activated drug development. Theranostics 2012, 2:156.
-
(2012)
Theranostics
, vol.2
, pp. 156
-
-
Choi, K.Y.1
-
44
-
-
84927127531
-
Controlled delivery of BID protein fused with TAT peptide sensitizes cancer cells to apoptosis
-
Orzechowska E.J., et al. Controlled delivery of BID protein fused with TAT peptide sensitizes cancer cells to apoptosis. BMC Cancer 2014, 14:771.
-
(2014)
BMC Cancer
, vol.14
, pp. 771
-
-
Orzechowska, E.J.1
-
45
-
-
84902551145
-
Matrix metalloproteinase 2-responsive micelle for siRNA delivery
-
Wang H-X., et al. Matrix metalloproteinase 2-responsive micelle for siRNA delivery. Biomaterials 2014, 35:7622-7634.
-
(2014)
Biomaterials
, vol.35
, pp. 7622-7634
-
-
Wang, H.-X.1
-
46
-
-
84878451456
-
Octa-arginine-modified pegylated liposomal doxorubicin: an effective treatment strategy for non-small cell lung cancer
-
Biswas S., et al. Octa-arginine-modified pegylated liposomal doxorubicin: an effective treatment strategy for non-small cell lung cancer. Cancer Lett. 2013, 335:191-200.
-
(2013)
Cancer Lett.
, vol.335
, pp. 191-200
-
-
Biswas, S.1
-
47
-
-
84920396574
-
Enhanced intracellular translocation and biodistribution of gold nanoparticles functionalized with a cell-penetrating peptide (VG-21) from vesicular stomatitis virus
-
Tiwari P.M., et al. Enhanced intracellular translocation and biodistribution of gold nanoparticles functionalized with a cell-penetrating peptide (VG-21) from vesicular stomatitis virus. Biomaterials 2014, 35:9484-9494.
-
(2014)
Biomaterials
, vol.35
, pp. 9484-9494
-
-
Tiwari, P.M.1
-
48
-
-
27744525788
-
Evaluation of cell penetrating peptides fused to elastin-like polypeptide for drug delivery
-
Massodi I., et al. Evaluation of cell penetrating peptides fused to elastin-like polypeptide for drug delivery. J. Control. Release 2005, 108:396-408.
-
(2005)
J. Control. Release
, vol.108
, pp. 396-408
-
-
Massodi, I.1
-
49
-
-
0037452668
-
Cell transfection in vitro and in vivo with nontoxic TAT peptide-liposome-DNA complexes
-
Torchilin V.P., et al. Cell transfection in vitro and in vivo with nontoxic TAT peptide-liposome-DNA complexes. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:1972-1977.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 1972-1977
-
-
Torchilin, V.P.1
-
50
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
-
Matsumura Y., Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res. 1986, 46:6387-6392.
-
(1986)
Cancer Res.
, vol.46
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
51
-
-
60749108001
-
Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect
-
Maeda H., et al. Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect. Eur. J. Pharm. Biopharm. 2009, 71:409-419.
-
(2009)
Eur. J. Pharm. Biopharm.
, vol.71
, pp. 409-419
-
-
Maeda, H.1
-
52
-
-
84893653202
-
Dendrimer as nanocarrier for drug delivery
-
Kesharwani P., et al. Dendrimer as nanocarrier for drug delivery. Prog. Polymer Sci. 2014, 39:268-307.
-
(2014)
Prog. Polymer Sci.
, vol.39
, pp. 268-307
-
-
Kesharwani, P.1
-
53
-
-
84915767964
-
Theranostic nanoparticles
-
Chen F., et al. Theranostic nanoparticles. J. Nucl. Med. 2014, 55:1919-1922.
-
(2014)
J. Nucl. Med.
, vol.55
, pp. 1919-1922
-
-
Chen, F.1
-
54
-
-
34447258534
-
Quantum dots and multifunctional nanoparticles: new contrast agents for tumor imaging
-
Rhyner M.N., et al. Quantum dots and multifunctional nanoparticles: new contrast agents for tumor imaging. Nanomedicine 2006, 1:209-217.
-
(2006)
Nanomedicine
, vol.1
, pp. 209-217
-
-
Rhyner, M.N.1
-
55
-
-
84873179175
-
Photostable fluorescent organic dots with aggregation-induced emission (AIE dots) for noninvasive long-term cell tracing
-
Li K., et al. Photostable fluorescent organic dots with aggregation-induced emission (AIE dots) for noninvasive long-term cell tracing. Sci. Rep. 2013, 3:1150.
-
(2013)
Sci. Rep.
, vol.3
, pp. 1150
-
-
Li, K.1
-
56
-
-
84907200459
-
Combination of antibody targeting and PTD-mediated intracellular toxin delivery for colorectal cancer therapy
-
Shin M.C., et al. Combination of antibody targeting and PTD-mediated intracellular toxin delivery for colorectal cancer therapy. J. Control. Release 2014, 194:197-210.
-
(2014)
J. Control. Release
, vol.194
, pp. 197-210
-
-
Shin, M.C.1
-
57
-
-
14644392093
-
Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay
-
Parker N., et al. Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay. Anal. Biochem. 2005, 338:284-293.
-
(2005)
Anal. Biochem.
, vol.338
, pp. 284-293
-
-
Parker, N.1
-
58
-
-
0027406702
-
Trophoblast and ovarian cancer antigen LK26. Sensitivity and specificity in immunopathology and molecular identification as a folate-binding protein
-
Garin-Chesa P., et al. Trophoblast and ovarian cancer antigen LK26. Sensitivity and specificity in immunopathology and molecular identification as a folate-binding protein. Am. J. Pathol. 1993, 142:557.
-
(1993)
Am. J. Pathol.
, vol.142
, pp. 557
-
-
Garin-Chesa, P.1
-
59
-
-
84875152889
-
Folic acid-tethered Pep-1 peptide-conjugated liposomal nanocarrier for enhanced intracellular drug delivery to cancer cells: conformational characterization and in vitro cellular uptake evaluation
-
Kang M.J., et al. Folic acid-tethered Pep-1 peptide-conjugated liposomal nanocarrier for enhanced intracellular drug delivery to cancer cells: conformational characterization and in vitro cellular uptake evaluation. Int. J. Nanomedicine 2013, 8:1155.
-
(2013)
Int. J. Nanomedicine
, vol.8
, pp. 1155
-
-
Kang, M.J.1
-
60
-
-
72449180818
-
Integrins
-
Barczyk M., et al. Integrins. Cell Tissue Res. 2010, 339:269-280.
-
(2010)
Cell Tissue Res.
, vol.339
, pp. 269-280
-
-
Barczyk, M.1
-
61
-
-
84896493907
-
Paclitaxel loaded liposomes decorated with a multifunctional tandem peptide for glioma targeting
-
Liu Y., et al. Paclitaxel loaded liposomes decorated with a multifunctional tandem peptide for glioma targeting. Biomaterials 2014, 35:4835-4847.
-
(2014)
Biomaterials
, vol.35
, pp. 4835-4847
-
-
Liu, Y.1
-
62
-
-
84940564466
-
Elastin-like polypeptide for improved drug delivery for anticancer therapy: preclinical studies and future applications
-
Ryu J.S., Raucher D. Elastin-like polypeptide for improved drug delivery for anticancer therapy: preclinical studies and future applications. Expert Opin. Drug Deliv. 2014, 1-15.
-
(2014)
Expert Opin. Drug Deliv.
, pp. 1-15
-
-
Ryu, J.S.1
Raucher, D.2
-
63
-
-
23144442466
-
Application of thermally responsive polypeptides directed against c-Myc transcriptional function for cancer therapy
-
Bidwell G.L., Raucher D. Application of thermally responsive polypeptides directed against c-Myc transcriptional function for cancer therapy. Mol. Cancer Ther. 2005, 4:1076-1085.
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 1076-1085
-
-
Bidwell, G.L.1
Raucher, D.2
-
64
-
-
84908370947
-
Elastin-like polypeptides: the influence of its molecular weight on local hyperthermia-induced tumor accumulation
-
Ryu J.S., Raucher D. Elastin-like polypeptides: the influence of its molecular weight on local hyperthermia-induced tumor accumulation. Eur. J. Pharm. Biopharm. 2014, 88:382-389.
-
(2014)
Eur. J. Pharm. Biopharm.
, vol.88
, pp. 382-389
-
-
Ryu, J.S.1
Raucher, D.2
-
65
-
-
84900508774
-
Anti-tumor efficacy of a therapeutic peptide based on thermo-responsive elastin-like polypeptide in combination with gemcitabine
-
Ryu J.S., Raucher D. Anti-tumor efficacy of a therapeutic peptide based on thermo-responsive elastin-like polypeptide in combination with gemcitabine. Cancer Lett. 2014, 348:177-184.
-
(2014)
Cancer Lett.
, vol.348
, pp. 177-184
-
-
Ryu, J.S.1
Raucher, D.2
-
66
-
-
84859505371
-
A thermally targeted c-Myc inhibitory polypeptide inhibits breast tumor growth
-
Bidwell G.L., et al. A thermally targeted c-Myc inhibitory polypeptide inhibits breast tumor growth. Cancer Lett. 2012, 319:136-143.
-
(2012)
Cancer Lett.
, vol.319
, pp. 136-143
-
-
Bidwell, G.L.1
-
67
-
-
73549108720
-
Inhibition of ovarian cancer cell proliferation by a cell cycle inhibitory peptide fused to a thermally responsive polypeptide carrier
-
Massodi I., et al. Inhibition of ovarian cancer cell proliferation by a cell cycle inhibitory peptide fused to a thermally responsive polypeptide carrier. Int. J. Cancer 2010, 126:533-544.
-
(2010)
Int. J. Cancer
, vol.126
, pp. 533-544
-
-
Massodi, I.1
-
68
-
-
84883333001
-
Fusogenic-oligoarginine peptide-mediated delivery of siRNAs targeting the CIP2A oncogene into oral cancer cells
-
Cantini L., et al. Fusogenic-oligoarginine peptide-mediated delivery of siRNAs targeting the CIP2A oncogene into oral cancer cells. PLoS ONE 2013, 8:e73348.
-
(2013)
PLoS ONE
, vol.8
, pp. e73348
-
-
Cantini, L.1
-
69
-
-
84896759012
-
PEGylated liposomes with NGR ligand and heat-activable cell-penetrating peptide-doxorubicin conjugate for tumor-specific therapy
-
Yang Y., et al. PEGylated liposomes with NGR ligand and heat-activable cell-penetrating peptide-doxorubicin conjugate for tumor-specific therapy. Biomaterials 2014, 35:4368-4381.
-
(2014)
Biomaterials
, vol.35
, pp. 4368-4381
-
-
Yang, Y.1
-
70
-
-
84872560827
-
Real-time in vivo molecular detection of primary tumors and metastases with ratiometric activatable cell-penetrating peptides
-
Savariar E.N., et al. Real-time in vivo molecular detection of primary tumors and metastases with ratiometric activatable cell-penetrating peptides. Cancer Res. 2013, 73:855-864.
-
(2013)
Cancer Res.
, vol.73
, pp. 855-864
-
-
Savariar, E.N.1
-
71
-
-
84902655584
-
Dual targeting of integrin αvβ3 and matrix metalloproteinase-2 for optical imaging of tumors and chemotherapeutic delivery
-
Crisp J.L., et al. Dual targeting of integrin αvβ3 and matrix metalloproteinase-2 for optical imaging of tumors and chemotherapeutic delivery. Mol. Cancer Ther. 2014, 13:1514-1525.
-
(2014)
Mol. Cancer Ther.
, vol.13
, pp. 1514-1525
-
-
Crisp, J.L.1
-
72
-
-
0024379967
-
Acid pH in tumors and its potential for therapeutic exploitation
-
Tannock I.F., Rotin D. Acid pH in tumors and its potential for therapeutic exploitation. Cancer Res. 1989, 49:4373-4384.
-
(1989)
Cancer Res.
, vol.49
, pp. 4373-4384
-
-
Tannock, I.F.1
Rotin, D.2
-
74
-
-
33746674416
-
'SMART' drug delivery systems: double-targeted pH-responsive pharmaceutical nanocarriers
-
Sawant R., et al. 'SMART' drug delivery systems: double-targeted pH-responsive pharmaceutical nanocarriers. Bioconjug. Chem. 2006, 17:943-949.
-
(2006)
Bioconjug. Chem.
, vol.17
, pp. 943-949
-
-
Sawant, R.1
-
75
-
-
79960226262
-
Physiology and pathophysiology of matrix metalloproteases
-
Klein T., Bischoff R. Physiology and pathophysiology of matrix metalloproteases. Amino Acids 2011, 41:271-290.
-
(2011)
Amino Acids
, vol.41
, pp. 271-290
-
-
Klein, T.1
Bischoff, R.2
-
76
-
-
70449732503
-
Matrix metalloproteinases as novel biomarker s and potential therapeutic targets in human cancer
-
Roy R., et al. Matrix metalloproteinases as novel biomarker s and potential therapeutic targets in human cancer. J. Clin. Oncol. 2009, 27:5287-5297.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 5287-5297
-
-
Roy, R.1
-
77
-
-
33645571901
-
Matrix metalloproteinases in bone marrow: roles of gelatinases in physiological hematopoiesis and hematopoietic malignancies
-
Yu X., Han Z. Matrix metalloproteinases in bone marrow: roles of gelatinases in physiological hematopoiesis and hematopoietic malignancies. Histol. Histopathol. 2006, 21:519-531.
-
(2006)
Histol. Histopathol.
, vol.21
, pp. 519-531
-
-
Yu, X.1
Han, Z.2
-
78
-
-
84903625230
-
Legumain protease-activated TAT-liposome cargo for targeting tumours and their microenvironment
-
Liu Z., et al. Legumain protease-activated TAT-liposome cargo for targeting tumours and their microenvironment. Nat. Commun. 2014, 5:4280.
-
(2014)
Nat. Commun.
, vol.5
, pp. 4280
-
-
Liu, Z.1
-
79
-
-
84878782419
-
Cell-penetrating peptides: 20 years later, where do we stand?
-
Bechara C., Sagan S. Cell-penetrating peptides: 20 years later, where do we stand?. FEBS Lett. 2013, 587:1693-1702.
-
(2013)
FEBS Lett.
, vol.587
, pp. 1693-1702
-
-
Bechara, C.1
Sagan, S.2
-
80
-
-
38949206876
-
Cell penetrating peptide conjugates of steric block oligonucleotides
-
Lebleu B., et al. Cell penetrating peptide conjugates of steric block oligonucleotides. Adv. Drug Deliv. Rev. 2008, 60:517-529.
-
(2008)
Adv. Drug Deliv. Rev.
, vol.60
, pp. 517-529
-
-
Lebleu, B.1
-
81
-
-
78650155418
-
Efficacy and safety evaluation of a novel botulinum toxin topical gel for the treatment of moderate to severe lateral canthal lines
-
Brandt F., et al. Efficacy and safety evaluation of a novel botulinum toxin topical gel for the treatment of moderate to severe lateral canthal lines. Dermatol. Surg. 2010, 36(Suppl. 4):2111-2118.
-
(2010)
Dermatol. Surg.
, vol.36
, pp. 2111-2118
-
-
Brandt, F.1
-
82
-
-
59949098048
-
Cell permeant peptide analogues of the small heat shock protein, HSP20, reduce TGF-beta1-induced CTGF expression in keloid fibroblasts
-
Lopes L.B., et al. Cell permeant peptide analogues of the small heat shock protein, HSP20, reduce TGF-beta1-induced CTGF expression in keloid fibroblasts. J. Invest. Dermatol. 2009, 129:590-598.
-
(2009)
J. Invest. Dermatol.
, vol.129
, pp. 590-598
-
-
Lopes, L.B.1
-
83
-
-
84876183998
-
The safety and efficacy of KAI-1678- an inhibitor of epsilon protein kinase C (epsilonPKC)-versus lidocaine and placebo for the treatment of postherpetic neuralgia: a crossover study design
-
Cousins M.J., et al. The safety and efficacy of KAI-1678- an inhibitor of epsilon protein kinase C (epsilonPKC)-versus lidocaine and placebo for the treatment of postherpetic neuralgia: a crossover study design. Pain Med. 2013, 14:533-540.
-
(2013)
Pain Med.
, vol.14
, pp. 533-540
-
-
Cousins, M.J.1
-
84
-
-
80052801329
-
Distribution of KAI-9803, a novel delta-protein kinase C inhibitor, after intravenous administration to rats
-
Miyaji Y., et al. Distribution of KAI-9803, a novel delta-protein kinase C inhibitor, after intravenous administration to rats. Drug Metab. Dispos. 2011, 39:1946-1953.
-
(2011)
Drug Metab. Dispos.
, vol.39
, pp. 1946-1953
-
-
Miyaji, Y.1
-
85
-
-
84875420696
-
A first-in-class, first-in-human, phase I trial of p28, a non-HDM2-mediated peptide inhibitor of p53 ubiquitination in patients with advanced solid tumours
-
Warso M.A., et al. A first-in-class, first-in-human, phase I trial of p28, a non-HDM2-mediated peptide inhibitor of p53 ubiquitination in patients with advanced solid tumours. Br. J. Cancer 2013, 108:1061-1070.
-
(2013)
Br. J. Cancer
, vol.108
, pp. 1061-1070
-
-
Warso, M.A.1
-
86
-
-
80052722389
-
A cell penetrating peptide derived from azurin inhibits angiogenesis and tumor growth by inhibiting phosphorylation of VEGFR-2, FAK and Akt
-
Mehta R.R., et al. A cell penetrating peptide derived from azurin inhibits angiogenesis and tumor growth by inhibiting phosphorylation of VEGFR-2, FAK and Akt. Angiogenesis 2011, 14:355-369.
-
(2011)
Angiogenesis
, vol.14
, pp. 355-369
-
-
Mehta, R.R.1
-
87
-
-
84940555156
-
First-in-human phase I and pharmacokinetic study of DTS-108 in patients with advanced carcinomas
-
Coriat R., et al. First-in-human phase I and pharmacokinetic study of DTS-108 in patients with advanced carcinomas. J. Clin. Oncol. 2012, 30(Suppl.):2557.
-
(2012)
J. Clin. Oncol.
, vol.30
, pp. 2557
-
-
Coriat, R.1
-
88
-
-
84884131045
-
Cytoplasm-responsive nanocarriers conjugated with a functional cell-penetrating peptide for systemic siRNA delivery
-
Tanaka K., et al. Cytoplasm-responsive nanocarriers conjugated with a functional cell-penetrating peptide for systemic siRNA delivery. Int. J. Pharm. 2013, 455:40-47.
-
(2013)
Int. J. Pharm.
, vol.455
, pp. 40-47
-
-
Tanaka, K.1
-
89
-
-
84872805989
-
A novel cell-penetrating peptide TAT-A1 delivers siRNA into tumor cells selectively
-
Fang B., et al. A novel cell-penetrating peptide TAT-A1 delivers siRNA into tumor cells selectively. Biochimie 2013, 95:251-257.
-
(2013)
Biochimie
, vol.95
, pp. 251-257
-
-
Fang, B.1
-
90
-
-
84937688292
-
Tumor imaging and targeting potential of an Hsp70-derived 14-mer peptide
-
Gehrmann M., et al. Tumor imaging and targeting potential of an Hsp70-derived 14-mer peptide. PLoS ONE 2014, 9:e105344.
-
(2014)
PLoS ONE
, vol.9
, pp. e105344
-
-
Gehrmann, M.1
-
91
-
-
84901424244
-
Simultaneous imaging and restoration of cell function using cell permeable peptide probe
-
Suh J.S., et al. Simultaneous imaging and restoration of cell function using cell permeable peptide probe. Biomaterials 2014, 35:6287-6298.
-
(2014)
Biomaterials
, vol.35
, pp. 6287-6298
-
-
Suh, J.S.1
-
92
-
-
84876078890
-
Cell penetration and cell-selective drug delivery using α-helix peptides conjugated with gold nanoparticles
-
Park H., et al. Cell penetration and cell-selective drug delivery using α-helix peptides conjugated with gold nanoparticles. Biomaterials 2013, 34:4872-4879.
-
(2013)
Biomaterials
, vol.34
, pp. 4872-4879
-
-
Park, H.1
-
93
-
-
84919621614
-
Enhanced cellular uptake of a TAT-conjugated peptide inhibitor targeting the polo-box domain of polo-like kinase 1
-
Kim S.M., et al. Enhanced cellular uptake of a TAT-conjugated peptide inhibitor targeting the polo-box domain of polo-like kinase 1. Amino Acids 2014, 46:2595-2603.
-
(2014)
Amino Acids
, vol.46
, pp. 2595-2603
-
-
Kim, S.M.1
-
94
-
-
84906536749
-
A WXW motif is required for the anticancer activity of the TAT-RasGAP317-326 peptide
-
Barras D., et al. A WXW motif is required for the anticancer activity of the TAT-RasGAP317-326 peptide. J. Biol. Chem. 2014, 289:23701-23711.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 23701-23711
-
-
Barras, D.1
-
95
-
-
84898727051
-
LXXLL peptide converts transportan 10 to a potent inducer of apoptosis in breast cancer cells
-
Tints K., et al. LXXLL peptide converts transportan 10 to a potent inducer of apoptosis in breast cancer cells. Int. J. Mol. Sci. 2014, 15:5680-5698.
-
(2014)
Int. J. Mol. Sci.
, vol.15
, pp. 5680-5698
-
-
Tints, K.1
-
96
-
-
84899509680
-
A specific STAT3-binding peptide exerts antiproliferative effects and antitumor activity by inhibiting STAT3 phosphorylation and signaling
-
Kim D., et al. A specific STAT3-binding peptide exerts antiproliferative effects and antitumor activity by inhibiting STAT3 phosphorylation and signaling. Cancer Res. 2014, 74:2144-2151.
-
(2014)
Cancer Res.
, vol.74
, pp. 2144-2151
-
-
Kim, D.1
-
97
-
-
84884994343
-
VDAC1-based peptides: novel pro-apoptotic agents and potential therapeutics for B-cell chronic lymphocytic leukemia
-
Prezma T., et al. VDAC1-based peptides: novel pro-apoptotic agents and potential therapeutics for B-cell chronic lymphocytic leukemia. Cell Death Dis. 2013, 4:e809.
-
(2013)
Cell Death Dis.
, vol.4
, pp. e809
-
-
Prezma, T.1
-
98
-
-
84871920565
-
Oligopeptides derived from autophosphorylation sites of EGF receptor suppress EGF-stimulated responses in human lung carcinoma A549 cells
-
Kuroda Y., et al. Oligopeptides derived from autophosphorylation sites of EGF receptor suppress EGF-stimulated responses in human lung carcinoma A549 cells. Eur. J. Pharmacol. 2013, 698:87-94.
-
(2013)
Eur. J. Pharmacol.
, vol.698
, pp. 87-94
-
-
Kuroda, Y.1
-
99
-
-
84871645347
-
TAT-mediated gp96 transduction to APCs enhances gp96-induced antiviral and antitumor T cell responses
-
Zhao B., et al. TAT-mediated gp96 transduction to APCs enhances gp96-induced antiviral and antitumor T cell responses. Vaccine 2013, 31:545-552.
-
(2013)
Vaccine
, vol.31
, pp. 545-552
-
-
Zhao, B.1
-
100
-
-
33846510441
-
Development of elastin-like polypeptide for thermally targeted delivery of doxorubicin
-
Bidwell G.L., et al. Development of elastin-like polypeptide for thermally targeted delivery of doxorubicin. Biochem. Pharmacol. 2007, 73:620-631.
-
(2007)
Biochem. Pharmacol.
, vol.73
, pp. 620-631
-
-
Bidwell, G.L.1
-
101
-
-
34250620539
-
A thermally targeted elastin-like polypeptide-doxorubicin conjugate overcomes drug resistance
-
Bidwell G.L., et al. A thermally targeted elastin-like polypeptide-doxorubicin conjugate overcomes drug resistance. Invest. New Drugs 2007, 25:313-326.
-
(2007)
Invest. New Drugs
, vol.25
, pp. 313-326
-
-
Bidwell, G.L.1
-
102
-
-
29144445979
-
Enhancing the antiproliferative effect of topoisomerase II inhibitors using a polypeptide inhibitor of c-Myc
-
Bidwell G.L., Raucher D. Enhancing the antiproliferative effect of topoisomerase II inhibitors using a polypeptide inhibitor of c-Myc. Biochem. Pharmacol. 2006, 71:248-256.
-
(2006)
Biochem. Pharmacol.
, vol.71
, pp. 248-256
-
-
Bidwell, G.L.1
Raucher, D.2
-
103
-
-
61449119855
-
Inhibition of ovarian cancer cell metastasis by a fusion polypeptide Tat-ELP
-
Massodi I., et al. Inhibition of ovarian cancer cell metastasis by a fusion polypeptide Tat-ELP. Clin. Exp. Metastasis 2009, 26:251-260.
-
(2009)
Clin. Exp. Metastasis
, vol.26
, pp. 251-260
-
-
Massodi, I.1
-
104
-
-
67649834226
-
Application of thermally responsive elastin-like polypeptide fused to a lactoferrin-derived peptide for treatment of pancreatic cancer
-
Massodi I., et al. Application of thermally responsive elastin-like polypeptide fused to a lactoferrin-derived peptide for treatment of pancreatic cancer. Molecules 2009, 14:1999-2015.
-
(2009)
Molecules
, vol.14
, pp. 1999-2015
-
-
Massodi, I.1
-
105
-
-
84867334463
-
Anticancer activity of proapoptotic peptides is highly improved by thermal targeting using elastin-like polypeptides
-
Moktan S., Raucher D. Anticancer activity of proapoptotic peptides is highly improved by thermal targeting using elastin-like polypeptides. Int. J. Pept. Res. Ther. 2012, 18:227-237.
-
(2012)
Int. J. Pept. Res. Ther.
, vol.18
, pp. 227-237
-
-
Moktan, S.1
Raucher, D.2
-
106
-
-
77951254936
-
A thermally targeted peptide inhibitor of symmetrical dimethylation inhibits cancer-cell proliferation
-
Bidwell G.L., et al. A thermally targeted peptide inhibitor of symmetrical dimethylation inhibits cancer-cell proliferation. Peptides 2010, 31:834-841.
-
(2010)
Peptides
, vol.31
, pp. 834-841
-
-
Bidwell, G.L.1
|