Distribution of KAI-9803, a novel δ-protein kinase C inhibitor, after intravenous administration to rats

Drug Metabolism and Disposition

Volumn 39, Issue 10, 2011, Pages 1946-1953

  Miyaji, Yoshihiro ^a   Walter, Sarah ^b   Chen, Leon ^b   Kurihara, Atsushi ^a   Ishizuka, Tomoko ^a   Saito, Motoko ^a   Kawai, Kenji ^a,c   Okazaki, Osamu ^a  

^a DAIICHI SANKYO CO   (Japan)

^b KAI Pharmaceuticals   (United States)

^c SHIN NIPPON BIOMEDICAL LABORATORIES LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 14; DRUG CARRIER; IODINE 125; KAI 9803; PROTEIN KINASE C INHIBITOR; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; ENDOTHELIUM CELL; HEART; HEART MUSCLE CELL; IN VITRO STUDY; INTERNALIZATION; ISOTOPE LABELING; KIDNEY; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE;

ANIMALS; AUTORADIOGRAPHY; CELL-PENETRATING PEPTIDES; CELLS, CULTURED; GENE PRODUCTS, TAT; INJECTIONS, INTRAVENOUS; MALE; MYOCYTES, CARDIAC; PEPTIDES; PROTEIN KINASE C-DELTA; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION;

HUMAN IMMUNODEFICIENCY VIRUS 1; RATTUS;

EID: 80052801329     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.111.040725     Document Type: Article

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