A proapoptotic peptide conjugated to penetratin selectively inhibits tumor cell growth

Biochimica et Biophysica Acta - Biomembranes

Volumn 1838, Issue 8, 2014, Pages 2087-2098

  Alves, Isabel D ^a   Carré, Manon ^b   Montero, Marie Pierre ^b   Castano, Sabine ^a   Lecomte, Sophie ^a   Marquant, Rodrigue ^c   Lecorché, Pascaline ^c   Burlina, Fabienne ^c   Schatz, Christophe ^d   Sagan, Sandrine ^c   Chassaing, Gérard ^c   Braguer, Diane ^b,e   Lavielle, Solange ^c  

^a CNRS   (France)

^b University of the Mediterranean Aix Marseille II   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d UNIVERSITÉ BORDEAUX 1   (France)

^e TIMONE HOSPITAL   (France)

Author keywords

Apoptotic peptide; Cell penetrating peptide; Lipid model systems; Mitochondria disruption; Peptide lipid interaction; Tumor cell growth inhibition

Indexed keywords

ACETYL LYSYLLEUCYLALANYLLYSYLLEUCYLALANYLLYSINE AMIDE; ACETYL LYSYLLEUCYLALANYLLYSYLLEUCYLALANYLLYSINE AMIDE PENETRATIN CONJUGATE; ANTINEOPLASTIC AGENT; CYTOTOXIC AGENT; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CALORIMETRY; CANCER CELL; CIRCULAR DICHROISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG MECHANISM; DRUG SELECTIVITY; DRUG STRUCTURE; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; LIGHT SCATTERING; MITOCHONDRIAL MEMBRANE; MITOSIS INHIBITION; PRIORITY JOURNAL; THERMODYNAMICS;

EUKARYOTA;

APOPTOTIC PEPTIDE; CELL PENETRATING PEPTIDE; LIPID MODEL SYSTEMS; MITOCHONDRIA DISRUPTION; PEPTIDE LIPID INTERACTION; TUMOR CELL GROWTH INHIBITION;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; CALORIMETRY, DIFFERENTIAL SCANNING; CARRIER PROTEINS; CIRCULAR DICHROISM; HUMANS; LIPOSOMES; MEMBRANE LIPIDS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; NEOPLASMS; PEPTIDES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TUMOR CELLS, CULTURED;

EID: 84900758830     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2014.04.025     Document Type: Article

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