-
1
-
-
1542288949
-
Secondary active transport mediated by a prokaryotic homologue of ClC Cl- channels
-
A. Accardi, and C. Miller Secondary active transport mediated by a prokaryotic homologue of ClC Cl- channels Nature 427 2004 803 807
-
(2004)
Nature
, vol.427
, pp. 803-807
-
-
Accardi, A.1
Miller, C.2
-
2
-
-
0026467045
-
Electrical measurements on endomembranes
-
A. Bertl, E. Blumwald, R. Coronado, R. Eisenberg, G. Findlay, D. Gradmann, B. Hille, K. Köhler, H.-A. Kolb, E. MacRobbie, and et al. Electrical measurements on endomembranes Science 258 1992 873 874
-
(1992)
Science
, vol.258
, pp. 873-874
-
-
Bertl, A.1
Blumwald, E.2
Coronado, R.3
Eisenberg, R.4
Findlay, G.5
Gradmann, D.6
Hille, B.7
Köhler, K.8
Kolb, H.-A.9
MacRobbie, E.10
-
3
-
-
84874105202
-
MTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state
-
C. Cang, Y. Zhou, B. Navarro, Y.-J. Seo, K. Aranda, L. Shi, S. Battaglia-Hsu, I. Nissim, D.E. Clapham, and D. Ren mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state Cell 152 2013 778 790
-
(2013)
Cell
, vol.152
, pp. 778-790
-
-
Cang, C.1
Zhou, Y.2
Navarro, B.3
Seo, Y.-J.4
Aranda, K.5
Shi, L.6
Battaglia-Hsu, S.7
Nissim, I.8
Clapham, D.E.9
Ren, D.10
-
4
-
-
84901235419
-
The voltage-gated sodium channel TPC1 confers endolysosomal excitability
-
C. Cang, B. Bekele, and D. Ren The voltage-gated sodium channel TPC1 confers endolysosomal excitability Nat. Chem. Biol. 10 2014 463 469
-
(2014)
Nat. Chem. Biol.
, vol.10
, pp. 463-469
-
-
Cang, C.1
Bekele, B.2
Ren, D.3
-
6
-
-
9444225430
-
The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing
-
J. Cerny, Y. Feng, A. Yu, K. Miyake, B. Borgonovo, J. Klumperman, J. Meldolesi, P.L. McNeil, and T. Kirchhausen The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing EMBO Rep. 5 2004 883 888
-
(2004)
EMBO Rep.
, vol.5
, pp. 883-888
-
-
Cerny, J.1
Feng, Y.2
Yu, A.3
Miyake, K.4
Borgonovo, B.5
Klumperman, J.6
Meldolesi, J.7
McNeil, P.L.8
Kirchhausen, T.9
-
7
-
-
84878707013
-
An extended proteome map of the lysosomal membrane reveals novel potential transporters
-
A. Chapel, S. Kieffer-Jaquinod, C. Sagné, Q. Verdon, C. Ivaldi, M. Mellal, J. Thirion, M. Jadot, C. Bruley, J. Garin, and et al. An extended proteome map of the lysosomal membrane reveals novel potential transporters Mol. Cell. Proteomics 12 2013 1572 1588
-
(2013)
Mol. Cell. Proteomics
, vol.12
, pp. 1572-1588
-
-
Chapel, A.1
Kieffer-Jaquinod, S.2
Sagné, C.3
Verdon, Q.4
Ivaldi, C.5
Mellal, M.6
Thirion, J.7
Jadot, M.8
Bruley, C.9
Garin, J.10
-
8
-
-
0036472494
-
PH-dependent regulation of lysosomal calcium in macrophages
-
K.A. Christensen, J.T. Myers, and J.A. Swanson pH-dependent regulation of lysosomal calcium in macrophages J. Cell Sci. 115 2002 599 607
-
(2002)
J. Cell Sci.
, vol.115
, pp. 599-607
-
-
Christensen, K.A.1
Myers, J.T.2
Swanson, J.A.3
-
9
-
-
0035355199
-
NAADP induces Ca2+ oscillations via a two-pool mechanism by priming IP3- and cADPR-sensitive Ca2+ stores
-
G.C. Churchill, and A. Galione NAADP induces Ca2+ oscillations via a two-pool mechanism by priming IP3- and cADPR-sensitive Ca2+ stores EMBO J. 20 2001 2666 2671
-
(2001)
EMBO J.
, vol.20
, pp. 2666-2671
-
-
Churchill, G.C.1
Galione, A.2
-
10
-
-
80051473235
-
PI(3,5)P(2) controls membrane trafficking by direct activation of mucolipin Ca(2+) release channels in the endolysosome
-
X.P. Dong, D. Shen, X. Wang, T. Dawson, X. Li, Q. Zhang, X. Cheng, Y. Zhang, L.S. Weisman, M. Delling, and H. Xu PI(3,5)P(2) controls membrane trafficking by direct activation of mucolipin Ca(2+) release channels in the endolysosome Nat. Commun. 1 2010 38
-
(2010)
Nat. Commun.
, vol.1
, pp. 38
-
-
Dong, X.P.1
Shen, D.2
Wang, X.3
Dawson, T.4
Li, X.5
Zhang, Q.6
Cheng, X.7
Zhang, Y.8
Weisman, L.S.9
Delling, M.10
Xu, H.11
-
11
-
-
0032478818
-
The structure of the potassium channel: Molecular basis of K+ conduction and selectivity
-
D.A. Doyle, J. Morais Cabral, R.A. Pfuetzner, A. Kuo, J.M. Gulbis, S.L. Cohen, B.T. Chait, and R. MacKinnon The structure of the potassium channel: molecular basis of K+ conduction and selectivity Science 280 1998 69 77
-
(1998)
Science
, vol.280
, pp. 69-77
-
-
Doyle, D.A.1
Morais Cabral, J.2
Pfuetzner, R.A.3
Kuo, A.4
Gulbis, J.M.5
Cohen, S.L.6
Chait, B.T.7
MacKinnon, R.8
-
13
-
-
44849107047
-
The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes
-
A.R. Graves, P.K. Curran, C.L. Smith, and J.A. Mindell The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes Nature 453 2008 788 792
-
(2008)
Nature
, vol.453
, pp. 788-792
-
-
Graves, A.R.1
Curran, P.K.2
Smith, C.L.3
Mindell, J.A.4
-
14
-
-
84907329806
-
High susceptibility to fatty liver disease in two-pore channel 2-deficient mice
-
C. Grimm, L.M. Holdt, C.C. Chen, S. Hassan, C. Müller, S. Jörs, H. Cuny, S. Kissing, B. Schröder, E. Butz, and et al. High susceptibility to fatty liver disease in two-pore channel 2-deficient mice Nat. Commun. 5 2014 4699
-
(2014)
Nat. Commun.
, vol.5
, pp. 4699
-
-
Grimm, C.1
Holdt, L.M.2
Chen, C.C.3
Hassan, S.4
Müller, C.5
Jörs, S.6
Cuny, H.7
Kissing, S.8
Schröder, B.9
Butz, E.10
-
15
-
-
67049172475
-
Defective organellar acidification as a cause of cystic fibrosis lung disease: Reexamination of a recurring hypothesis
-
P.M. Haggie, and A.S. Verkman Defective organellar acidification as a cause of cystic fibrosis lung disease: reexamination of a recurring hypothesis Am. J. Physiol. Lung Cell. Mol. Physiol. 296 2009 L859 L867
-
(2009)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.296
, pp. L859-L867
-
-
Haggie, P.M.1
Verkman, A.S.2
-
17
-
-
0016785479
-
PH gradient across the lysosomal membrane generated by selective cation permeability and Donnan equilibrium
-
R. Henning pH gradient across the lysosomal membrane generated by selective cation permeability and Donnan equilibrium Biochim. Biophys. Acta 401 1975 307 316
-
(1975)
Biochim. Biophys. Acta
, vol.401
, pp. 307-316
-
-
Henning, R.1
-
19
-
-
33947360830
-
The neuronal background K2P channels: Focus on TREK1
-
E. Honoré The neuronal background K2P channels: focus on TREK1 Nat. Rev. Neurosci. 8 2007 251 261
-
(2007)
Nat. Rev. Neurosci.
, vol.8
, pp. 251-261
-
-
Honoré, E.1
-
20
-
-
84870655957
-
Crystal structure of the calcium release-activated calcium channel Orai
-
X. Hou, L. Pedi, M.M. Diver, and S.B. Long Crystal structure of the calcium release-activated calcium channel Orai Science 338 2012 1308 1313
-
(2012)
Science
, vol.338
, pp. 1308-1313
-
-
Hou, X.1
Pedi, L.2
Diver, M.M.3
Long, S.B.4
-
21
-
-
84904703691
-
Targeting potassium channels in cancer
-
X. Huang, and L.Y. Jan Targeting potassium channels in cancer J. Cell Biol. 206 2014 151 162
-
(2014)
J. Cell Biol.
, vol.206
, pp. 151-162
-
-
Huang, X.1
Jan, L.Y.2
-
22
-
-
84903489855
-
P2X4 forms functional ATP-activated cation channels on lysosomal membranes regulated by luminal pH
-
P. Huang, Y. Zou, X.Z. Zhong, Q. Cao, K. Zhao, M.X. Zhu, R. Murrell-Lagnado, and X.P. Dong P2X4 forms functional ATP-activated cation channels on lysosomal membranes regulated by luminal pH J. Biol. Chem. 289 2014 17658 17667
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 17658-17667
-
-
Huang, P.1
Zou, Y.2
Zhong, X.Z.3
Cao, Q.4
Zhao, K.5
Zhu, M.X.6
Murrell-Lagnado, R.7
Dong, X.P.8
-
23
-
-
0038076054
-
X-ray structure of a voltage-dependent K+ channel
-
Y. Jiang, A. Lee, J. Chen, V. Ruta, M. Cadene, B.T. Chait, and R. MacKinnon X-ray structure of a voltage-dependent K+ channel Nature 423 2003 33 41
-
(2003)
Nature
, vol.423
, pp. 33-41
-
-
Jiang, Y.1
Lee, A.2
Chen, J.3
Ruta, V.4
Cadene, M.5
Chait, B.T.6
MacKinnon, R.7
-
24
-
-
84862295360
-
Guidelines for the use and interpretation of assays for monitoring autophagy
-
D.J. Klionsky, F.C. Abdalla, H. Abeliovich, R.T. Abraham, A. Acevedo-Arozena, K. Adeli, L. Agholme, M. Agnello, P. Agostinis, J.A. Aguirre-Ghiso, and et al. Guidelines for the use and interpretation of assays for monitoring autophagy Autophagy 8 2012 445 544
-
(2012)
Autophagy
, vol.8
, pp. 445-544
-
-
Klionsky, D.J.1
Abdalla, F.C.2
Abeliovich, H.3
Abraham, R.T.4
Acevedo-Arozena, A.5
Adeli, K.6
Agholme, L.7
Agnello, M.8
Agostinis, P.9
Aguirre-Ghiso, J.A.10
-
25
-
-
79960169252
-
In situ measurement of the electrical potential across the lysosomal membrane using FRET
-
M. Koivusalo, B.E. Steinberg, D. Mason, and S. Grinstein In situ measurement of the electrical potential across the lysosomal membrane using FRET Traffic 12 2011 972 982
-
(2011)
Traffic
, vol.12
, pp. 972-982
-
-
Koivusalo, M.1
Steinberg, B.E.2
Mason, D.3
Grinstein, S.4
-
26
-
-
0032077277
-
A novel inward rectifier K+ channel with unique pore properties
-
G. Krapivinsky, I. Medina, L. Eng, L. Krapivinsky, Y. Yang, and D.E. Clapham A novel inward rectifier K+ channel with unique pore properties Neuron 20 1998 995 1005
-
(1998)
Neuron
, vol.20
, pp. 995-1005
-
-
Krapivinsky, G.1
Medina, I.2
Eng, L.3
Krapivinsky, L.4
Yang, Y.5
Clapham, D.E.6
-
27
-
-
4444244825
-
Functional links between mucolipin-1 and Ca2+-dependent membrane trafficking in mucolipidosis IV
-
J.M. LaPlante, C.P. Ye, S.J. Quinn, E. Goldin, E.M. Brown, S.A. Slaugenhaupt, and P.M. Vassilev Functional links between mucolipin-1 and Ca2+-dependent membrane trafficking in mucolipidosis IV Biochem. Biophys. Res. Commun. 322 2004 1384 1391
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.322
, pp. 1384-1391
-
-
LaPlante, J.M.1
Ye, C.P.2
Quinn, S.J.3
Goldin, E.4
Brown, E.M.5
Slaugenhaupt, S.A.6
Vassilev, P.M.7
-
28
-
-
0024426645
-
Mutant potassium channels with altered binding of charybdotoxin, a pore-blocking peptide inhibitor
-
R. MacKinnon, and C. Miller Mutant potassium channels with altered binding of charybdotoxin, a pore-blocking peptide inhibitor Science 245 1989 1382 1385
-
(1989)
Science
, vol.245
, pp. 1382-1385
-
-
MacKinnon, R.1
Miller, C.2
-
29
-
-
4544378532
-
Mitochondrial fusion intermediates revealed in vitro
-
S. Meeusen, J.M. McCaffery, and J. Nunnari Mitochondrial fusion intermediates revealed in vitro Science 305 2004 1747 1752
-
(2004)
Science
, vol.305
, pp. 1747-1752
-
-
Meeusen, S.1
McCaffery, J.M.2
Nunnari, J.3
-
30
-
-
0028983387
-
The charybdotoxin family of K+ channel-blocking peptides
-
C. Miller The charybdotoxin family of K+ channel-blocking peptides Neuron 15 1995 5 10
-
(1995)
Neuron
, vol.15
, pp. 5-10
-
-
Miller, C.1
-
31
-
-
84857260144
-
Lysosomal acidification mechanisms
-
J.A. Mindell Lysosomal acidification mechanisms Annu. Rev. Physiol. 74 2012 69 86
-
(2012)
Annu. Rev. Physiol.
, vol.74
, pp. 69-86
-
-
Mindell, J.A.1
-
32
-
-
81055144784
-
Autophagy: Renovation of cells and tissues
-
N. Mizushima, and M. Komatsu Autophagy: renovation of cells and tissues Cell 147 2011 728 741
-
(2011)
Cell
, vol.147
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
34
-
-
84866158866
-
Detecting pore-lining regions in transmembrane protein sequences
-
T. Nugent, and D.T. Jones Detecting pore-lining regions in transmembrane protein sequences BMC Bioinformatics 13 2012 169
-
(2012)
BMC Bioinformatics
, vol.13
, pp. 169
-
-
Nugent, T.1
Jones, D.T.2
-
35
-
-
34848916433
-
Luminal chloride-dependent activation of endosome calcium channels: Patch clamp study of enlarged endosomes
-
M. Saito, P.I. Hanson, and P. Schlesinger Luminal chloride-dependent activation of endosome calcium channels: patch clamp study of enlarged endosomes J. Biol. Chem. 282 2007 27327 27333
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 27327-27333
-
-
Saito, M.1
Hanson, P.I.2
Schlesinger, P.3
-
36
-
-
84923815384
-
Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment
-
Y. Sakurai, A.A. Kolokoltsov, C.C. Chen, M.W. Tidwell, W.E. Bauta, N. Klugbauer, C. Grimm, C. Wahl-Schott, M. Biel, and R.A. Davey Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment Science 347 2015 995 998
-
(2015)
Science
, vol.347
, pp. 995-998
-
-
Sakurai, Y.1
Kolokoltsov, A.A.2
Chen, C.C.3
Tidwell, M.W.4
Bauta, W.E.5
Klugbauer, N.6
Grimm, C.7
Wahl-Schott, C.8
Biel, M.9
Davey, R.A.10
-
37
-
-
35948985511
-
Integral and associated lysosomal membrane proteins
-
B. Schröder, C. Wrocklage, C. Pan, R. Jäger, B. Kösters, H. Schäfer, H.P. Elsässer, M. Mann, and A. Hasilik Integral and associated lysosomal membrane proteins Traffic 8 2007 1676 1686
-
(2007)
Traffic
, vol.8
, pp. 1676-1686
-
-
Schröder, B.1
Wrocklage, C.2
Pan, C.3
Jäger, R.4
Kösters, B.5
Schäfer, H.6
Elsässer, H.P.7
Mann, M.8
Hasilik, A.9
-
38
-
-
84873690749
-
Chloride in vesicular trafficking and function
-
T. Stauber, and T.J. Jentsch Chloride in vesicular trafficking and function Annu. Rev. Physiol. 75 2013 453 477
-
(2013)
Annu. Rev. Physiol.
, vol.75
, pp. 453-477
-
-
Stauber, T.1
Jentsch, T.J.2
-
39
-
-
77954412381
-
A cation counterflux supports lysosomal acidification
-
B.E. Steinberg, K.K. Huynh, A. Brodovitch, S. Jabs, T. Stauber, T.J. Jentsch, and S. Grinstein A cation counterflux supports lysosomal acidification J. Cell Biol. 189 2010 1171 1186
-
(2010)
J. Cell Biol.
, vol.189
, pp. 1171-1186
-
-
Steinberg, B.E.1
Huynh, K.K.2
Brodovitch, A.3
Jabs, S.4
Stauber, T.5
Jentsch, T.J.6
Grinstein, S.7
-
40
-
-
0028261425
-
Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis
-
H. Stenmark, R.G. Parton, O. Steele-Mortimer, A. Lütcke, J. Gruenberg, and M. Zerial Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis EMBO J. 13 1994 1287 1296
-
(1994)
EMBO J.
, vol.13
, pp. 1287-1296
-
-
Stenmark, H.1
Parton, R.G.2
Steele-Mortimer, O.3
Lütcke, A.4
Gruenberg, J.5
Zerial, M.6
-
41
-
-
0034641869
-
Mucolipidosis type IV is caused by mutations in a gene encoding a novel transient receptor potential channel
-
M. Sun, E. Goldin, S. Stahl, J.L. Falardeau, J.C. Kennedy, J.S. Acierno Jr., C. Bove, C.R. Kaneski, J. Nagle, M.C. Bromley, and et al. Mucolipidosis type IV is caused by mutations in a gene encoding a novel transient receptor potential channel Hum. Mol. Genet. 9 2000 2471 2478
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2471-2478
-
-
Sun, M.1
Goldin, E.2
Stahl, S.3
Falardeau, J.L.4
Kennedy, J.C.5
Acierno, J.S.6
Bove, C.7
Kaneski, C.R.8
Nagle, J.9
Bromley, M.C.10
-
42
-
-
84892370435
-
Structural basis for Ca2+ selectivity of a voltage-gated calcium channel
-
L. Tang, T.M. Gamal El-Din, J. Payandeh, G.Q. Martinez, T.M. Heard, T. Scheuer, N. Zheng, and W.A. Catterall Structural basis for Ca2+ selectivity of a voltage-gated calcium channel Nature 505 2014 56 61
-
(2014)
Nature
, vol.505
, pp. 56-61
-
-
Tang, L.1
Gamal El-Din, T.M.2
Payandeh, J.3
Martinez, G.Q.4
Heard, T.M.5
Scheuer, T.6
Zheng, N.7
Catterall, W.A.8
-
43
-
-
84926382243
-
A voltage-gated calcium channel regulates lysosomal fusion with endosomes and autophagosomes and is required for neuronal homeostasis
-
X. Tian, U. Gala, Y. Zhang, W. Shang, S. Nagarkar Jaiswal, A. di Ronza, M. Jaiswal, S. Yamamoto, H. Sandoval, L. Duraine, and et al. A voltage-gated calcium channel regulates lysosomal fusion with endosomes and autophagosomes and is required for neuronal homeostasis PLoS Biol. 13 2015 e1002103
-
(2015)
PLoS Biol.
, vol.13
, pp. e1002103
-
-
Tian, X.1
Gala, U.2
Zhang, Y.3
Shang, W.4
Nagarkar Jaiswal, S.5
Di Ronza, A.6
Jaiswal, M.7
Yamamoto, S.8
Sandoval, H.9
Duraine, L.10
-
44
-
-
0034786532
-
The HMMTOP transmembrane topology prediction server
-
G.E. Tusnády, and I. Simon The HMMTOP transmembrane topology prediction server Bioinformatics 17 2001 849 850
-
(2001)
Bioinformatics
, vol.17
, pp. 849-850
-
-
Tusnády, G.E.1
Simon, I.2
-
45
-
-
84867565289
-
TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes
-
X. Wang, X. Zhang, X.P. Dong, M. Samie, X. Li, X. Cheng, A. Goschka, D. Shen, Y. Zhou, J. Harlow, and et al. TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes Cell 151 2012 372 383
-
(2012)
Cell
, vol.151
, pp. 372-383
-
-
Wang, X.1
Zhang, X.2
Dong, X.P.3
Samie, M.4
Li, X.5
Cheng, X.6
Goschka, A.7
Shen, D.8
Zhou, Y.9
Harlow, J.10
-
46
-
-
84922794140
-
Lysosomal physiology
-
H. Xu, and D. Ren Lysosomal physiology Annu. Rev. Physiol. 77 2015 57 80
-
(2015)
Annu. Rev. Physiol.
, vol.77
, pp. 57-80
-
-
Xu, H.1
Ren, D.2
-
47
-
-
0027340610
-
Molecular determinants of Ca2+ selectivity and ion permeation in L-type Ca2+ channels
-
J. Yang, P.T. Ellinor, W.A. Sather, J.F. Zhang, and R.W. Tsien Molecular determinants of Ca2+ selectivity and ion permeation in L-type Ca2+ channels Nature 366 1993 158 161
-
(1993)
Nature
, vol.366
, pp. 158-161
-
-
Yang, J.1
Ellinor, P.T.2
Sather, W.A.3
Zhang, J.F.4
Tsien, R.W.5
-
48
-
-
0025800956
-
Mutations affecting internal TEA blockade identify the probable pore-forming region of a K+ channel
-
G. Yellen, M.E. Jurman, T. Abramson, and R. MacKinnon Mutations affecting internal TEA blockade identify the probable pore-forming region of a K+ channel Science 251 1991 939 942
-
(1991)
Science
, vol.251
, pp. 939-942
-
-
Yellen, G.1
Jurman, M.E.2
Abramson, T.3
MacKinnon, R.4
-
49
-
-
77749297933
-
Calcium signaling via two-pore channels: Local or global, that is the question
-
M.X. Zhu, J. Ma, J. Parrington, P.J. Calcraft, A. Galione, and A.M. Evans Calcium signaling via two-pore channels: local or global, that is the question Am. J. Physiol. Cell Physiol. 298 2010 C430 C441
-
(2010)
Am. J. Physiol. Cell Physiol.
, vol.298
, pp. C430-C441
-
-
Zhu, M.X.1
Ma, J.2
Parrington, J.3
Calcraft, P.J.4
Galione, A.5
Evans, A.M.6
-
50
-
-
0027336649
-
Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores
-
A. Zweifach, and R.S. Lewis Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores Proc. Natl. Acad. Sci. USA 90 1993 6295 6299
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6295-6299
-
-
Zweifach, A.1
Lewis, R.S.2
|