The correlations between BRCA1 defect and environmental factors in the risk of breast cancer

Journal of Toxicological Sciences

Volumn 38, Issue 3, 2013, Pages 355-361

  Kang, Hyo Jin ^a   Bin Hong, Young ^a,e   Weon Yi, Yong ^a,b   Cho, Chi Heum ^c   Wang, Antai ^d   Bae, Insoo ^a,b  

^a GEORGETOWN UNIVERSITY   (United States)

^b Dankook University   (South Korea)

^c Keimyung University School of Medicine   (South Korea)

^d Columbia University ^*  (United States)

^e Ewha Womans University School of Medicine   (South Korea)

Author keywords

BRCA1; Breast cancer; Environmental factors; Genetic factor; Tumorigenesis

Indexed keywords

2, 3, 7, 8 TETRACHLORODIBENZO PARA DIOXIN; BENZO [A] PYRENE; BRCA1 PROTEIN; CYTOCHROME P450 1B1; DIMETHYLBENZ [A] ANTHRACENE; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

BREAST CANCER; BREAST CARCINOGENESIS; BREAST EPITHELIUM; CANCER RISK; CELL CULTURE; CONTROLLED STUDY; DNA DAMAGE; ENVIRONMENTAL FACTOR; HEREDITY; HUMAN; HUMAN CELL; LETTER;

EID: 84877784943     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.38.355     Document Type: Letter

References (29)

1. Abdelrahim, M., Ariazi, E., Kim, K., Khan, S., Barhoumi, R., Burghardt, R., Liu, S., Hill, D., Finnell, R., Wlodarczyk, B., Jordan, V.C. and Safe S., (2006),3-methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha. Cancer Res., 66, 2459-2467.
2. Bae, I., Fan, S., Meng, Q., Rih, J.K., Kim, H.J., Kang, H.J., Xu, J., Goldberg, I.D., Jaiswal, A.K. and Rosen, E.M. (2004): BRCA1 induces antioxidant gene expression and resistance to oxidative stress. Cancer Res., 64, 7893-7909.
3. 32P-postlabeling. Cancer Lett., 65, 35-41.
4. Carvan, M.J., Flood, L.P., Campbell, B.D. and Busbee, D.L. (1995): Effects of benzo(a)pyrene and tetrachlorodibenzo(p) dioxin on fetal dolphin kidney cells: inhibition of proliferation and initiation of DNA damage. Chemosphere, 30, 187-198.
5. Denison, M.S. and Nagy, S.R. (2003): Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu. Rev. Pharmacol. Toxicol., 43, 309-334.
6. Denison, M.S., Soshilov, A.A., He, G., DeGroot, D.E. and Zhao, B. (2011): Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor. Toxicol. Sci., 124, 1-22.
7. de Waard, P.W., de Kok, T.M., Maas, L.M., Peijnenburg, A.A., Hoogenboom, R.L., Aarts, J.M., van Schooten, F.J. (2008): Influence of TCDD and natural Ah receptor agonists on benzo[a] pyrene-DNA adduct formation in the Caco-2 human colon cell line. Mutagenesis, 23, 67-73.
8. Dunnick, J.K., Elwell, M.R., Huff, J. and Barrett, J.C. (1995): Chemically induced mammary gland cancer in the National Toxicology Program's carcinogenesis bioassay. Carcinogenesis, 16, 173-179.
9. Easton, D., Ford, D. and Peto, J. (1993): Inherited susceptibility to breast cancer. Cancer Surv., 18, 95-113.
10. Harrigan, J.A., McGarrigle, B.P., Sutter, T.R. and Olson, J.R. (2006): Tissue specific induction of cytochrome P450 (CYP) 1A1 and 1B1 in rat liver and lung following in vitro (tissue slice) and in vivo exposure to benzo(a)pyrene. Toxicol. In Vitro, 20, 426-438.
11. Ibarluzea, J.M., Fernández, M.F.,Santa-Marina, L., Olea-Serrano, M.F., Rivas, A.M., Aurrekoetxea, J.J., Expósito, J.,Lorenzo, M., Torné, P.,Villalobos, M., Pedraza, V., Sasco, A.J. and Olea, N. (2004): Breast cancer risk and the combined effect of environmental estrogens. Cancer Causes Control, 15, 591-600.
12. Kang, H.J., Kim, H.J., Kim, S.K., Barouki, R., Cho, C.H., Khanna, K.K., Rosen, E.M. and Bae, I. (2006): BRCA1 modulates xenobiotic stress-inducible gene expression by interacting with ARNT in human Breast Cancer Cells. J. Biol. Chem., 281, 14654-14662.
13. Kang, H.J., Kim, H.J., Cho, C.H., Hu, Y., Li, R. and Bae, I. (2008a): BRCA1 transcriptional activity is enhanced by interactions between its AD1 domain and AhR. Cancer Chemother. Pharmacol., 62, 965-975.
14. Kang, H.J., Kim, H.J., Kwon, S.H., Kang, B.D., Eling, T.E., Lee, S.H. and Bae, I. (2008b): BRCA1 modulates sensitivity to 5F-203 by regulating xenobiotic stress-inducible protein levels and EROD activity. Cancer Chemother.Pharmacol., 62, 689-697.
15. Kang, H.J., Hong, Y.B., Kim, H.J., Rodriguez, O.C., Nath, R.G., Tilli, E.M., Albanese, C., Chung, F.L., Kwon, S.H. and Bae I. (2011): Detoxification: a novel function of BRCA1 in tumor suppression? Toxicol. Sci., 122, 26-37.
16. Kang, H.J., Hong, Y.B., Kim, H.J., Wang, A. and Bae, I. (2012): Bioactive food components prevent carcinogenic stress vis Nrf2 activation in BRCA1 deficient breast epithelial cells. Toxicol. Lett., 209, 154-160.
17. Kang, H.J., Hong, Y.B., Kim, H.J., Yi, Y.W., Nath, R.G., Chang, Y.S., Cho, H.C. and Bae, I. (2011b): A novel in vitro pancreatic carcinogenesis model. Toxicol. Lett., 202, 15-22.
18. Kang, S.C. and Lee, B.M. (2005): Effect of estrogen receptor (ER) on benzo[a]pyrene-DNA adduct formation in human breast cancer cells. J. Toxicol. Environ. Health A, 68, 1833-1840.
19. Lichtenstein, P., Holm, N.V., Verkasalo, P.K., Iliadou, A., Kaprio, J., Koskenvuo, M., Pukkala, E., Skytthe, A. and Hemminki, K. (2000): Environmental and heritable factors in the causation of cancer: analyses of cohorts of twins from Sweden, Denmark and Finland. N. Engl. J. Med., 343, 78-85.
20. Martinez-Outschoorn, U.E, Balliet, R., Lin, Z., Whitaker- Menezes, D., Birbe, R.C, Bombonati, A., Pavlides, S., Lamb, R., Sneddon, S., Howell, A., Sotgia, F. and Lisanti, M.P. (2012a): BRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: implications for breast cancer prevention with antioxidant therapies. Cell Cycle, 11, 4402-4413.
21. Martinez-Outschoorn, U.E., Balliet, R.M., Lin, Z., Whitaker- Menezes, D., Howell, A., Sotgia, F. and Lisanti, M.P. (2012b) Hereditary ovarian cancer and two-compartment tumor metabolism: epithelial loss of BRCA1 induces hydrogen peroxide production, driving oxidative stress and NFκB activation in the tumor stroma. Cell Cycle, 11, 4152-4166.
22. Nathanson, K.L., Wooster, R., Weber, B.L. and Nathanson, K.N. (2001): Breast cancer genetics: what we know and what we need. Nat. Med., 7, 552-556.
23. Pang, S., Cao, J.Q., Katz, B.H., Hayes, C.L., Sutter, T.R. and Spink, D.C. (1999): Inductive and inhibitory effects of non-ortho-substituted polychlorinated biphenyls on estrogen metabolism and human cytochromes P450 1A1 and 1B1. Biochem. Pharmacol., 58, 29-38.
24. Saha, T., Rih, J.K. and Rosen, E.M. (2009): BRCA1 down-regulates cellular levels of reactive oxygen species. FEBS Lett., 583, 1535-1543.
25. Salgo, M.G., Cueto, R., Winston, G.W. and Pryor, W.A. (1999): Beta carotene and its oxidation products have different effects on microsome mediated binding of benzo[a]pyrene to DNA. Free Radic. Biol. Med., 26, 162-173.
26. Soule, H.D., Maloney, T.M., Wolman, S.R., Peterson, W.D.Jr., Brenz, R., McGrath, C.M., Russo, J., Pauley, R.J., Jones, R.F. and Brooks, S.C. (1990): Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. Cancer Res., 50, 6075-6086.
27. van Schanke, A., Boon, J.P., Aardoom, Y., van Leest, A., van Schooten, F.J., Maas, L., van den Berg, M. and Everaarts, J.M. (2000): Effect of a dioxin-like PCB (CB 126) on the biotransformation and genotoxicity of benzo[a]pyrene in the marine flatfish dab (Limanda limanda). Aquat. Toxicol., 50, 403-415.
28. Wolff, M.S., Collman, G.W., Barrett, J.C. and Huff, J. (1996): Breast cancer and environmental risk factors: epidemiological and experimental findings. Annu. Rev. Pharmacol. Toxicol., 36, 573-596.
29. Xu, C., Li, C.Y. and Kong, A.N. (2005): Induction of phase I, II and III drug metabolism/transport by xenobiotics. Arch. Pharm. Res., 28, 249-268.