메뉴 건너뛰기




Volumn 195, Issue 5, 2015, Pages 1955-1963

Genetic interaction between Lyn, Ets1, and Btk in the control of antibody levels

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; BRUTON TYROSINE KINASE; CD69 ANTIGEN; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; PROTEIN KINASE LYN; TRANSCRIPTION FACTOR ETS 1; AGAMMAGLOBULINAEMIA TYROSINE KINASE; ANTIBODY; ETS1 PROTEIN, MOUSE; IMMUNOGLOBULIN M; LYN PROTEIN-TYROSINE KINASE; PROTEIN TYROSINE KINASE;

EID: 84940118449     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1500165     Document Type: Article
Times cited : (19)

References (56)
  • 1
    • 84892472283 scopus 로고    scopus 로고
    • Transcription factor Ets1, but not the closely related factor Ets2, inhibits antibody-secreting cell differentiation
    • John, S., L. Russell, S. S. Chin, W. Luo, R. Oshima, and L. A. Garrett-Sinha. 2014. Transcription factor Ets1, but not the closely related factor Ets2, inhibits antibody-secreting cell differentiation. Mol. Cell. Biol. 34: 522-532.
    • (2014) Mol. Cell. Biol. , vol.34 , pp. 522-532
    • John, S.1    Russell, L.2    Chin, S.S.3    Luo, W.4    Oshima, R.5    Garrett-Sinha, L.A.6
  • 2
    • 38149064569 scopus 로고    scopus 로고
    • Ets-1 regulates plasma cell differentiation by interfering with the activity of the transcription factor Blimp-1
    • John, S. A., J. L. Clements, L. M. Russell, and L. A. Garrett-Sinha. 2008. Ets-1 regulates plasma cell differentiation by interfering with the activity of the transcription factor Blimp-1. J. Biol. Chem. 283: 951-962.
    • (2008) J. Biol. Chem. , vol.283 , pp. 951-962
    • John, S.A.1    Clements, J.L.2    Russell, L.M.3    Garrett-Sinha, L.A.4
  • 3
    • 84883466291 scopus 로고    scopus 로고
    • Review of Ets1 structure, function, and roles in immunity
    • Garrett-Sinha, L. A. 2013. Review of Ets1 structure, function, and roles in immunity. Cell. Mol. Life Sci. 70: 3375-3390.
    • (2013) Cell. Mol. Life Sci. , vol.70 , pp. 3375-3390
    • Garrett-Sinha, L.A.1
  • 4
    • 24144443497 scopus 로고    scopus 로고
    • Ets-1 deficiency leads to altered B cell differentiation, hyperresponsiveness to TLR9 and autoimmune disease
    • Wang, D., S. A. John, J. L. Clements, D. H. Percy, K. P. Barton, and L. A. Garrett-Sinha. 2005. Ets-1 deficiency leads to altered B cell differentiation, hyperresponsiveness to TLR9 and autoimmune disease. Int. Immunol. 17: 1179-1191.
    • (2005) Int. Immunol. , vol.17 , pp. 1179-1191
    • Wang, D.1    John, S.A.2    Clements, J.L.3    Percy, D.H.4    Barton, K.P.5    Garrett-Sinha, L.A.6
  • 5
    • 84904256707 scopus 로고    scopus 로고
    • A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels
    • Luo, W., J. Mayeux, T. Gutierrez, L. Russell, A. Getahun, J. Müller, T. Tedder, J. Parnes, R. Rickert, L. Nitschke, et al. 2014. A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels. J. Immunol. 193: 909-920.
    • (2014) J. Immunol. , vol.193 , pp. 909-920
    • Luo, W.1    Mayeux, J.2    Gutierrez, T.3    Russell, L.4    Getahun, A.5    Müller, J.6    Tedder, T.7    Parnes, J.8    Rickert, R.9    Nitschke, L.10
  • 6
    • 0032191918 scopus 로고    scopus 로고
    • The Ets-1 transcription factor is required for the development of natural killer cells in mice
    • Barton, K., N. Muthusamy, C. Fischer, C. N. Ting, T. L. Walunas, L. L. Lanier, and J. M. Leiden. 1998. The Ets-1 transcription factor is required for the development of natural killer cells in mice. Immunity 9: 555-563.
    • (1998) Immunity , vol.9 , pp. 555-563
    • Barton, K.1    Muthusamy, N.2    Fischer, C.3    Ting, C.N.4    Walunas, T.L.5    Lanier, L.L.6    Leiden, J.M.7
  • 8
    • 84900502897 scopus 로고    scopus 로고
    • Gene-gene interactions of IRF5, STAT4, IKZF1 and ETS1 in systemic lupus erythematosus
    • Dang, J., S. Shan, J. Li, H. Zhao, Q. Xin, Y. Liu, X. Bian, and Q. Liu. 2014. Gene-gene interactions of IRF5, STAT4, IKZF1 and ETS1 in systemic lupus erythematosus. Tissue Antigens 83: 401-408.
    • (2014) Tissue Antigens , vol.83 , pp. 401-408
    • Dang, J.1    Shan, S.2    Li, J.3    Zhao, H.4    Xin, Q.5    Liu, Y.6    Bian, X.7    Liu, Q.8
  • 10
    • 84870941026 scopus 로고    scopus 로고
    • Gene-gene and gene-sex epistatic interactions of MiR146a, IRF5, IKZF1, ETS1 and IL21 in systemic lupus erythematosus
    • Leng, R. X., W. Wang, H. Cen, M. Zhou, C. C. Feng, Y. Zhu, X. K. Yang, M. Yang, Y. Zhai, B. Z. Li, et al. 2012. Gene-gene and gene-sex epistatic interactions of MiR146a, IRF5, IKZF1, ETS1 and IL21 in systemic lupus erythematosus. PLoS One 7: e51090.
    • (2012) PLoS One , vol.7 , pp. e51090
    • Leng, R.X.1    Wang, W.2    Cen, H.3    Zhou, M.4    Feng, C.C.5    Zhu, Y.6    Yang, X.K.7    Yang, M.8    Zhai, Y.9    Li, B.Z.10
  • 11
    • 81055148276 scopus 로고    scopus 로고
    • Replicated associations of TNFAIP3, TNIP1 and ETS1 with systemic lupus erythematosus in a southwestern Chinese population
    • Zhong, H., X. L. Li, M. Li, L. X. Hao, R. W. Chen, K. Xiang, X. B. Qi, R. Z. Ma, and B. Su. 2011. Replicated associations of TNFAIP3, TNIP1 and ETS1 with systemic lupus erythematosus in a southwestern Chinese population. Arthritis Res. Ther. 13: R186.
    • (2011) Arthritis Res. Ther. , vol.13 , pp. R186
    • Zhong, H.1    Li, X.L.2    Li, M.3    Hao, L.X.4    Chen, R.W.5    Xiang, K.6    Qi, X.B.7    Ma, R.Z.8    Su, B.9
  • 12
    • 77956127159 scopus 로고    scopus 로고
    • Expression analysis of ETS1 gene in peripheral blood mononuclear cells with systemic lupus erythematosus by real-time reverse transcription PCR
    • Li, Y., L. D. Sun, W. S. Lu, W. L. Hu, J. P. Gao, Y. L. Cheng, Z. Y. Yu, S. Yao, C. F. He, J. L. Liu, et al. 2010. Expression analysis of ETS1 gene in peripheral blood mononuclear cells with systemic lupus erythematosus by real-time reverse transcription PCR. Chin. Med. J. (Engl.) 123: 2287-2288.
    • (2010) Chin. Med. J. (Engl.) , vol.123 , pp. 2287-2288
    • Li, Y.1    Sun, L.D.2    Lu, W.S.3    Hu, W.L.4    Gao, J.P.5    Cheng, Y.L.6    Yu, Z.Y.7    Yao, S.8    He, C.F.9    Liu, J.L.10
  • 13
    • 77956261467 scopus 로고    scopus 로고
    • TNIP1, SLC15A4, ETS1, RasGRP3 and IKZF1 are associated with clinical features of systemic lupus erythematosus in a Chinese Han population
    • He, C. F., Y. S. Liu, Y. L. Cheng, J. P. Gao, T. M. Pan, J. W. Han, C. Quan, L. D. Sun, H. F. Zheng, X. B. Zuo, et al. 2010. TNIP1, SLC15A4, ETS1, RasGRP3 and IKZF1 are associated with clinical features of systemic lupus erythematosus in a Chinese Han population. Lupus 19: 1181-1186.
    • (2010) Lupus , vol.19 , pp. 1181-1186
    • He, C.F.1    Liu, Y.S.2    Cheng, Y.L.3    Gao, J.P.4    Pan, T.M.5    Han, J.W.6    Quan, C.7    Sun, L.D.8    Zheng, H.F.9    Zuo, X.B.10
  • 14
    • 77649206245 scopus 로고    scopus 로고
    • Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus
    • Asian Lupus Genetics Consortium
    • Yang,W., N. Shen, D. Q. Ye, Q. Liu, Y. Zhang, X. X. Qian, N. Hirankarn, D. Ying, H. F. Pan, C. C. Mok, et al; Asian Lupus Genetics Consortium. 2010. Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus. PLoS Genet. 6: e1000841.
    • (2010) PLoS Genet. , vol.6 , pp. e1000841
    • Yang, W.1    Shen, N.2    Ye, D.Q.3    Liu, Q.4    Zhang, Y.5    Qian, X.X.6    Hirankarn, N.7    Ying, D.8    Pan, H.F.9    Mok, C.C.10
  • 16
    • 70350629871 scopus 로고    scopus 로고
    • Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus
    • Han, J. W., H. F. Zheng, Y. Cui, L. D. Sun, D. Q. Ye, Z. Hu, J. H. Xu, Z. M. Cai, W. Huang, G. P. Zhao, et al. 2009. Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat. Genet. 41: 1234-1237.
    • (2009) Nat. Genet. , vol.41 , pp. 1234-1237
    • Han, J.W.1    Zheng, H.F.2    Cui, Y.3    Sun, L.D.4    Ye, D.Q.5    Hu, Z.6    Xu, J.H.7    Cai, Z.M.8    Huang, W.9    Zhao, G.P.10
  • 17
    • 84878045716 scopus 로고    scopus 로고
    • Auto-antibody induction by DNA-containing immune complexes requires HMGB1 with the TLR2/microRNA-155 pathway
    • Wen, Z., L. Xu, X. Chen, W. Xu, Z. Yin, X. Gao, and S. Xiong. 2013. Auto-antibody induction by DNA-containing immune complexes requires HMGB1 with the TLR2/microRNA-155 pathway. J. Immunol. 190: 5411-5422.
    • (2013) J. Immunol. , vol.190 , pp. 5411-5422
    • Wen, Z.1    Xu, L.2    Chen, X.3    Xu, W.4    Yin, Z.5    Gao, X.6    Xiong, S.7
  • 18
    • 84911964588 scopus 로고    scopus 로고
    • Expression of Ets-1 and FOXP3 mRNA in CD4(+)CD25 (+) T regulatory cells from patients with systemic lupus erythematosus
    • Xiang, N., X. P. Li, X. M. Li, G. S. Wang, J. H. Tao, H. F. Pan, X. Fang, Q. Ma, and N. Yu. 2014. Expression of Ets-1 and FOXP3 mRNA in CD4(+)CD25 (+) T regulatory cells from patients with systemic lupus erythematosus. Clin. Exp. Med. 14: 375-381.
    • (2014) Clin. Exp. Med. , vol.14 , pp. 375-381
    • Xiang, N.1    Li, X.P.2    Li, X.M.3    Wang, G.S.4    Tao, J.H.5    Pan, H.F.6    Fang, X.7    Ma, Q.8    Yu, N.9
  • 19
  • 20
    • 0030740148 scopus 로고    scopus 로고
    • Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation
    • Chan, V. W., F. Meng, P. Soriano, A. L. DeFranco, and C. A. Lowell. 1997. Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation. Immunity 7: 69-81.
    • (1997) Immunity , vol.7 , pp. 69-81
    • Chan, V.W.1    Meng, F.2    Soriano, P.3    DeFranco, A.L.4    Lowell, C.A.5
  • 23
    • 77954130384 scopus 로고    scopus 로고
    • Separate checkpoints regulate splenic plasma cell accumulation and IgG autoantibody production in Lyn-deficient mice
    • Gutierrez, T., K. E. Halcomb, A. J. Coughran, Q. Z. Li, and A. B. Satterthwaite. 2010. Separate checkpoints regulate splenic plasma cell accumulation and IgG autoantibody production in Lyn-deficient mice. Eur. J. Immunol. 40: 1897-1905.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 1897-1905
    • Gutierrez, T.1    Halcomb, K.E.2    Coughran, A.J.3    Li, Q.Z.4    Satterthwaite, A.B.5
  • 24
    • 0034987582 scopus 로고    scopus 로고
    • Regulation of B lymphocyte development and activation by Bruton's tyrosine kinase
    • Khan, W. N. 2001. Regulation of B lymphocyte development and activation by Bruton's tyrosine kinase. Immunol. Res. 23: 147-156.
    • (2001) Immunol. Res. , vol.23 , pp. 147-156
    • Khan, W.N.1
  • 25
    • 0032147181 scopus 로고    scopus 로고
    • Btk function in B cell development and response
    • Satterthwaite, A. B., Z. Li, and O. N. Witte. 1998. Btk function in B cell development and response. Semin. Immunol. 10: 309-316.
    • (1998) Semin. Immunol. , vol.10 , pp. 309-316
    • Satterthwaite, A.B.1    Li, Z.2    Witte, O.N.3
  • 26
    • 0032055485 scopus 로고    scopus 로고
    • SHIP modulates immune receptor responses by regulating membrane association of Btk
    • Bolland, S., R. N. Pearse, T. Kurosaki, and J. V. Ravetch. 1998. SHIP modulates immune receptor responses by regulating membrane association of Btk. Immunity 8: 509-516.
    • (1998) Immunity , vol.8 , pp. 509-516
    • Bolland, S.1    Pearse, R.N.2    Kurosaki, T.3    Ravetch, J.V.4
  • 27
    • 0033535614 scopus 로고    scopus 로고
    • Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1
    • Maeda, A., A. M. Scharenberg, S. Tsukada, J. B. Bolen, J. P. Kinet, and T. Kurosaki. 1999. Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1. Oncogene 18: 2291-2297.
    • (1999) Oncogene , vol.18 , pp. 2291-2297
    • Maeda, A.1    Scharenberg, A.M.2    Tsukada, S.3    Bolen, J.B.4    Kinet, J.P.5    Kurosaki, T.6
  • 28
    • 29144478403 scopus 로고    scopus 로고
    • Decreased Lyn expression and translocation to lipid raft signaling domains in B lymphocytes from patients with systemic lupus erythematosus
    • Flores-Borja, F., P. S. Kabouridis, E. C. Jury, D. A. Isenberg, and R. A. Mageed. 2005. Decreased Lyn expression and translocation to lipid raft signaling domains in B lymphocytes from patients with systemic lupus erythematosus. Arthritis Rheum. 52: 3955-3965.
    • (2005) Arthritis Rheum. , vol.52 , pp. 3955-3965
    • Flores-Borja, F.1    Kabouridis, P.S.2    Jury, E.C.3    Isenberg, D.A.4    Mageed, R.A.5
  • 31
    • 38649125210 scopus 로고    scopus 로고
    • Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
    • International Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN)
    • Harley, J. B., M. E. Alarcón-Riquelme, L. A. Criswell, C. O. Jacob, R. P. Kimberly, K. L. Moser, B. P. Tsao, T. J. Vyse, C. D. Langefeld, S. K. Nath, et al; International Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN). 2008. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat. Genet. 40: 204-210.
    • (2008) Nat. Genet. , vol.40 , pp. 204-210
    • Harley, J.B.1    Alarcón-Riquelme, M.E.2    Criswell, L.A.3    Jacob, C.O.4    Kimberly, R.P.5    Moser, K.L.6    Tsao, B.P.7    Vyse, T.J.8    Langefeld, C.D.9    Nath, S.K.10
  • 33
    • 84864806973 scopus 로고    scopus 로고
    • Genetic interdependence of Lyn and negative regulators of B cell receptor signaling in autoimmune disease development
    • Tsantikos, E., M. J. Maxwell, N. Kountouri, K. W. Harder, D. M. Tarlinton, and M. L. Hibbs. 2012. Genetic interdependence of Lyn and negative regulators of B cell receptor signaling in autoimmune disease development. J. Immunol. 189: 1726-1736.
    • (2012) J. Immunol. , vol.189 , pp. 1726-1736
    • Tsantikos, E.1    Maxwell, M.J.2    Kountouri, N.3    Harder, K.W.4    Tarlinton, D.M.5    Hibbs, M.L.6
  • 34
  • 37
    • 0028864666 scopus 로고
    • Defective activation and survival of T cells lacking the Ets-1 transcription factor
    • Muthusamy, N., K. Barton, and J. M. Leiden. 1995. Defective activation and survival of T cells lacking the Ets-1 transcription factor. Nature 377: 639-642.
    • (1995) Nature , vol.377 , pp. 639-642
    • Muthusamy, N.1    Barton, K.2    Leiden, J.M.3
  • 38
    • 9244259624 scopus 로고    scopus 로고
    • The development of early and mature B cells is impaired in mice deficient for the Ets-1 transcription factor
    • Eyquem, S., K. Chemin, M. Fasseu, M. Chopin, F. Sigaux, A. Cumano, and J. C. Bories. 2004. The development of early and mature B cells is impaired in mice deficient for the Ets-1 transcription factor. Eur. J. Immunol. 34: 3187-3196.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 3187-3196
    • Eyquem, S.1    Chemin, K.2    Fasseu, M.3    Chopin, M.4    Sigaux, F.5    Cumano, A.6    Bories, J.C.7
  • 41
    • 84893364183 scopus 로고    scopus 로고
    • Requirement for MyD88 signaling in B cells and dendritic cells for germinal center antinuclear antibody production in Lyn-deficient mice
    • Hua, Z., A. J. Gross, C. Lamagna, N. Ramos-Hernández, P. Scapini, M. Ji, H. Shao, C. A. Lowell, B. Hou, and A. L. DeFranco. 2014. Requirement for MyD88 signaling in B cells and dendritic cells for germinal center antinuclear antibody production in Lyn-deficient mice. J. Immunol. 192: 875-885.
    • (2014) J. Immunol. , vol.192 , pp. 875-885
    • Hua, Z.1    Gross, A.J.2    Lamagna, C.3    Ramos-Hernández, N.4    Scapini, P.5    Ji, M.6    Shao, H.7    Lowell, C.A.8    Hou, B.9    DeFranco, A.L.10
  • 43
    • 77955343903 scopus 로고    scopus 로고
    • Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice
    • Scapini, P., Y. Hu, C. L. Chu, T. S. Migone, A. L. Defranco, M. A. Cassatella, and C. A. Lowell. 2010. Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice. J. Exp. Med. 207: 1757-1773.
    • (2010) J. Exp. Med. , vol.207 , pp. 1757-1773
    • Scapini, P.1    Hu, Y.2    Chu, C.L.3    Migone, T.S.4    DeFranco, A.L.5    Cassatella, M.A.6    Lowell, C.A.7
  • 44
    • 33745867628 scopus 로고    scopus 로고
    • Impaired generation of CD8+ thymocytes in Ets-1-deficient mice
    • Clements, J. L., S. A. John, and L. A. Garrett-Sinha. 2006. Impaired generation of CD8+ thymocytes in Ets-1-deficient mice. J. Immunol. 177: 905-912.
    • (2006) J. Immunol. , vol.177 , pp. 905-912
    • Clements, J.L.1    John, S.A.2    Garrett-Sinha, L.A.3
  • 45
    • 77949322552 scopus 로고    scopus 로고
    • Autoimmune disease in Lyn-deficient mice is dependent on an inflammatory environment established by IL-6
    • Tsantikos, E., S. A. Oracki, C. Quilici, G. P. Anderson, D. M. Tarlinton, and M. L. Hibbs. 2010. Autoimmune disease in Lyn-deficient mice is dependent on an inflammatory environment established by IL-6. J. Immunol. 184: 1348-1360.
    • (2010) J. Immunol. , vol.184 , pp. 1348-1360
    • Tsantikos, E.1    Oracki, S.A.2    Quilici, C.3    Anderson, G.P.4    Tarlinton, D.M.5    Hibbs, M.L.6
  • 46
    • 84893392428 scopus 로고    scopus 로고
    • B cell-specific loss of Lyn kinase leads to autoimmunity
    • Lamagna, C., Y. Hu, A. L. DeFranco, and C. A. Lowell. 2014. B cell-specific loss of Lyn kinase leads to autoimmunity. J. Immunol. 192: 919-928.
    • (2014) J. Immunol. , vol.192 , pp. 919-928
    • Lamagna, C.1    Hu, Y.2    DeFranco, A.L.3    Lowell, C.A.4
  • 47
    • 84876730074 scopus 로고    scopus 로고
    • TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice
    • Rubtsov, A. V., K. Rubtsova, J. W. Kappler, and P. Marrack. 2013. TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice. Immunol. Res. 55: 210-216.
    • (2013) Immunol. Res. , vol.55 , pp. 210-216
    • Rubtsov, A.V.1    Rubtsova, K.2    Kappler, J.W.3    Marrack, P.4
  • 48
    • 80051568169 scopus 로고    scopus 로고
    • + B-cell population is important for the development of autoimmunity
    • Rubtsov, A. V., K. Rubtsova, A. Fischer, R. T. Meehan, J. Z. Gillis, J. W. Kappler, and P. Marrack. 2011. Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity. Blood 118: 1305-1315.
    • (2011) Blood , vol.118 , pp. 1305-1315
    • Rubtsov, A.V.1    Rubtsova, K.2    Fischer, A.3    Meehan, R.T.4    Gillis, J.Z.5    Kappler, J.W.6    Marrack, P.7
  • 49
    • 80051569441 scopus 로고    scopus 로고
    • A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice
    • Hao, Y., P. O'Neill, M. S. Naradikian, J. L. Scholz, and M. P. Cancro. 2011. A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice. Blood 118: 1294-1304.
    • (2011) Blood , vol.118 , pp. 1294-1304
    • Hao, Y.1    O'Neill, P.2    Naradikian, M.S.3    Scholz, J.L.4    Cancro, M.P.5
  • 53
    • 79952231757 scopus 로고    scopus 로고
    • Macrophage-derived BAFF induces AID expression through the p38MAPK/CREB and JNK/AP-1 pathways
    • Kim, H. A., G. Y. Seo, and P. H. Kim. 2011. Macrophage-derived BAFF induces AID expression through the p38MAPK/CREB and JNK/AP-1 pathways. J. Leukoc. Biol. 89: 393-398.
    • (2011) J. Leukoc. Biol. , vol.89 , pp. 393-398
    • Kim, H.A.1    Seo, G.Y.2    Kim, P.H.3
  • 55
    • 0035008059 scopus 로고    scopus 로고
    • Tracking the response of Xid B cells in vivo: TI-2 antigen induces migration and proliferation but Btk is essential for terminal differentiation
    • Vinuesa, C. G., Y. Sunners, J. Pongracz, J. Ball, K. M. Toellner, D. Taylor, I. C. MacLennan, and M. C. Cook. 2001. Tracking the response of Xid B cells in vivo: TI-2 antigen induces migration and proliferation but Btk is essential for terminal differentiation. Eur. J. Immunol. 31: 1340-1350.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1340-1350
    • Vinuesa, C.G.1    Sunners, Y.2    Pongracz, J.3    Ball, J.4    Toellner, K.M.5    Taylor, D.6    MacLennan, I.C.7    Cook, M.C.8
  • 56
    • 0034232062 scopus 로고    scopus 로고
    • Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response
    • Guinamard, R., M. Okigaki, J. Schlessinger, and J. V. Ravetch. 2000. Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response. Nat. Immunol. 1: 31-36.
    • (2000) Nat. Immunol. , vol.1 , pp. 31-36
    • Guinamard, R.1    Okigaki, M.2    Schlessinger, J.3    Ravetch, J.V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.