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Volumn 40, Issue 7, 2010, Pages 1897-1905

Separate checkpoints regulate splenic plasma cell accumulation and IgG autoantibody production in Lyn-deficient mice

Author keywords

Autoimmunity; Btk; IL 6; Lyn; Plasma cell

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; BRUTON TYROSINE KINASE; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M; INTERLEUKIN 6; NUCLEIC ACID; PROTEIN KINASE LYN; AGAMMAGLOBULINAEMIA TYROSINE KINASE; ANTINUCLEAR ANTIBODY; IMMUNOGLOBULIN G; LYN PROTEIN-TYROSINE KINASE; PROTEIN TYROSINE KINASE;

EID: 77954130384     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200940043     Document Type: Article
Times cited : (25)

References (49)
  • 1
    • 0035881627 scopus 로고    scopus 로고
    • Increased frequency of pre-germinal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus
    • Arce, E., Jackson, D. G., Gill, M. A., Bennett, L. B., Banchereau, J. and Pascual, V., Increased frequency of pre-germinal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus. J. Immunol. 2001. 167: 2361-2369.
    • (2001) J. Immunol. , vol.167 , pp. 2361-2369
    • Arce, E.1    Jackson, D.G.2    Gill, M.A.3    Bennett, L.B.4    Banchereau, J.5    Pascual, V.6
  • 2
    • 0028784215 scopus 로고
    • Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease
    • Hibbs, M. L., Tarlinton, D. M., Armes, J., Grail, D., Hodgson, G., Maglitto, R., Stacker, S. A. and Dunn, A. R., Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease. Cell 1995. 83: 301-311.
    • (1995) Cell , vol.83 , pp. 301-311
    • Hibbs, M.L.1    Tarlinton, D.M.2    Armes, J.3    Grail, D.4    Hodgson, G.5    Maglitto, R.6    Stacker, S.A.7    Dunn, A.R.8
  • 3
    • 0028806216 scopus 로고
    • Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice
    • Nishizumi, H., Taniuchi, I., Yamanashi, Y., Kitamura, D., Ilic, D., Mori, D., Watanabe, T. and Yamamoto, T., Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice. Immunity 1995. 3: 549-560.
    • (1995) Immunity , vol.3 , pp. 549-560
    • Nishizumi, H.1    Taniuchi, I.2    Yamanashi, Y.3    Kitamura, D.4    Ilic, D.5    Mori, D.6    Watanabe, T.7    Yamamoto, T.8
  • 4
    • 0030740148 scopus 로고    scopus 로고
    • Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation
    • Chan, V. W., Meng, F., Soriano, S., DeFranco, A. L. and Lowell, C. A., Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation. Immunity 1997. 7: 69-81.
    • (1997) Immunity , vol.7 , pp. 69-81
    • Chan, V.W.1    Meng, F.2    Soriano, S.3    DeFranco, A.L.4    Lowell, C.A.5
  • 6
    • 2942635727 scopus 로고    scopus 로고
    • Short-lived Plasmablasts and Long-lived Plasma Cells Contribute to Chronic Humoral Autoimmunity in NZB/WMice
    • Hoyer, B. F., Moser, K., Hauser, A. E., Peddinghaus, A., Voigt, C., Eilat, D., Radbruch, A. et al., Short-lived Plasmablasts and Long-lived Plasma Cells Contribute to Chronic Humoral Autoimmunity in NZB/WMice. J. Exp. Med. 2004. 199: 1577-1584.
    • (2004) J. Exp. Med. , vol.199 , pp. 1577-1584
    • Hoyer, B.F.1    Moser, K.2    Hauser, A.E.3    Peddinghaus, A.4    Voigt, C.5    Eilat, D.6    Radbruch, A.7
  • 7
    • 24144443497 scopus 로고    scopus 로고
    • Ets-1 deficiency leads to altered B cell differentiation, hyperresponsiveness to TLR9 and autoimmune disease
    • Wang, D., John, S. A., Clements, J. L., Percy, D. H., Barton, K. P. and Garrett-Sinha, L. A., Ets-1 deficiency leads to altered B cell differentiation, hyperresponsiveness to TLR9 and autoimmune disease. Int. Immunol. 2005. 17: 1179-1191.
    • (2005) Int. Immunol. , vol.17 , pp. 1179-1191
    • Wang, D.1    John, S.A.2    Clements, J.L.3    Percy, D.H.4    Barton, K.P.5    Garrett-Sinha, L.A.6
  • 8
    • 21144438325 scopus 로고    scopus 로고
    • A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity
    • Vinuesa, C. G., Cook, M. C., Angelucci, C., Athanasopoulos, V., Rui, L., Hill, K. M., Yu, D. et al., A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity. Nature 2005. 435: 452-458.
    • (2005) Nature , vol.435 , pp. 452-458
    • Vinuesa, C.G.1    Cook, M.C.2    Angelucci, C.3    Athanasopoulos, V.4    Rui, L.5    Hill, K.M.6    Yu, D.7
  • 11
    • 38649125210 scopus 로고    scopus 로고
    • Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
    • International Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN), Harley, J. B., Alarcón-Riquelme, M. E., Criswell, L. A., Jacob, C. O., Kimberly, R. P., Moser, K. L. et al.
    • International Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN), Harley, J. B., Alarcón-Riquelme, M. E., Criswell, L. A., Jacob, C. O., Kimberly, R. P., Moser, K. L. et al., Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat. Genet. 2008. 40: 204-210.
    • (2008) Nat. Genet. , vol.40 , pp. 204-210
  • 12
    • 12444331082 scopus 로고    scopus 로고
    • Lyn tyrosine kinase: Accentuating the positive and the negative
    • Xu, Y., Harder, K.W., Huntington, N. D., Hibbs, M. L. and Tarlinton, D. M., Lyn tyrosine kinase: accentuating the positive and the negative. Immunity 2005. 22: 9-18.
    • (2005) Immunity , vol.22 , pp. 9-18
    • Xu, Y.1    Harder, K.W.2    Huntington, N.D.3    Hibbs, M.L.4    Tarlinton, D.M.5
  • 13
    • 17944381147 scopus 로고    scopus 로고
    • Gain- and loss-of-function Lyn mutant mice define a critical inhibitory role for Lyn in the myeloid lineage
    • Harder, K. W., Parsons, L. M., Armes, J., Evans, N., Kountouri, N., Clark, R., Quilici, C. et al., Gain- and loss-of-function Lyn mutant mice define a critical inhibitory role for Lyn in the myeloid lineage. Immunity 2001. 15: 603-615.
    • (2001) Immunity , vol.15 , pp. 603-615
    • Harder, K.W.1    Parsons, L.M.2    Armes, J.3    Evans, N.4    Kountouri, N.5    Clark, R.6    Quilici, C.7
  • 14
    • 0041344445 scopus 로고    scopus 로고
    • The Lyn tyrosine kinase negatively regulates neutrophil integrin signaling
    • Pereira, S. and Lowell, C., The Lyn tyrosine kinase negatively regulates neutrophil integrin signaling. J. Immunol. 2003. 171: 1319-1327. (Pubitemid 36900063)
    • (2003) Journal of Immunology , vol.171 , Issue.3 , pp. 1319-1327
    • Pereira, S.1    Lowell, C.2
  • 15
    • 0030912071 scopus 로고    scopus 로고
    • Lipopolysaccharide (LPS)-induced macrophage activation and signal transduction in the absence of Src-family kinases Hck, Fgr, and Lyn
    • Meng, F. and Lowell, C., Lipopolysaccharide (LPS)-induced macrophage activation and signal transduction in the absence of Src-family kinases Hck, Fgr, and Lyn. J. Exp. Med. 1997. 185: 1661-1670.
    • (1997) J. Exp. Med. , vol.185 , pp. 1661-1670
    • Meng, F.1    Lowell, C.2
  • 18
    • 0042591464 scopus 로고    scopus 로고
    • Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals
    • Cassese, G., Arce, S., Hauser, A. E., Lehnert, K., Moewes, B., Mostarac, M., Muehlinghaus, G. et al., Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals. J. Immunol. 2003. 171: 1684-1690.
    • (2003) J. Immunol. , vol.171 , pp. 1684-1690
    • Cassese, G.1    Arce, S.2    Hauser, A.E.3    Lehnert, K.4    Moewes, B.5    Mostarac, M.6    Muehlinghaus, G.7
  • 19
    • 0037108354 scopus 로고    scopus 로고
    • The role of bone marrow-derived stromal cells in the maintenance of plasma cell longevity
    • Minges Wols, H. A., Underhill, G. H., Kansas, G. S. and Witte, P. L., The role of bone marrow-derived stromal cells in the maintenance of plasma cell longevity. J. Immunol. 2002. 169: 4213-4221.
    • (2002) J. Immunol. , vol.169 , pp. 4213-4221
    • Minges Wols, H.A.1    Underhill, G.H.2    Kansas, G.S.3    Witte, P.L.4
  • 21
    • 0025990288 scopus 로고
    • Elevated levels of endogenous IL-6 in systemic lupus erythematosus. A putative role in pathogenesis
    • Linker-Israeli, M., Deans, R. J.,Wallace, D. J., Prehn, J., Ozeri-Chen, T. and Klinenberg, J. R., Elevated levels of endogenous IL-6 in systemic lupus erythematosus. A putative role in pathogenesis. J. Immunol. 1991. 147: 117-123.
    • (1991) J. Immunol. , vol.147 , pp. 117-123
    • Linker-Israeli, M.1    Deans, R.J.2    Wallace, D.J.3    Prehn, J.4    Ozeri-Chen, T.5    Klinenberg, J.R.6
  • 23
    • 0027461333 scopus 로고
    • Macrophage depletion decreases IgG anti-DNA in cultures from (NZB x NZW)F1 spleen cells by eliminating the main source of IL-6
    • Alarcon-Riquelme, M. E., Moller, G. and Fernandez, C., Macrophage depletion decreases IgG anti-DNA in cultures from (NZB x NZW)F1 spleen cells by eliminating the main source of IL-6. Clin. Exp. Immunol. 1993. 91: 220-225.
    • (1993) Clin. Exp. Immunol. , vol.91 , pp. 220-225
    • Alarcon-Riquelme, M.E.1    Moller, G.2    Fernandez, C.3
  • 24
    • 0027930909 scopus 로고
    • Interleukin 6 promotes murine lupus in NZB/NZW F1 mice
    • Finck, B. K., Chan, B. andWofsy, D., Interleukin 6 promotes murine lupus in NZB/NZW F1 mice. J. Clin. Invest. 1994. 94: 585-591.
    • (1994) J. Clin. Invest. , vol.94 , pp. 585-591
    • Finck, B.K.1    Chan, B.2    Wofsy, D.3
  • 25
    • 0032055485 scopus 로고    scopus 로고
    • SHIP modulates immune receptor responses by regulating membrane association of Btk
    • Bolland, S., Pearse, R. N., Kurosaki, T. and Ravetch, J. V., SHIP modulates immune receptor responses by regulating membrane association of Btk. Immunity 1998. 8: 509-516.
    • (1998) Immunity , vol.8 , pp. 509-516
    • Bolland, S.1    Pearse, R.N.2    Kurosaki, T.3    Ravetch, J.V.4
  • 26
    • 0033535614 scopus 로고    scopus 로고
    • Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1
    • Maeda, A., Scharenberg, A. M., Tsukada, S., Bolen, J. B., Kinet, J. P. and Kurosaki, T., Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1. Oncogene 1999. 18: 2291-2297. (Pubitemid 29192706)
    • (1999) Oncogene , vol.18 , Issue.14 , pp. 2291-2297
    • Maeda, A.1    Scharenberg, A.M.2    Tsukada, S.3    Bolen, J.B.4    Kinet, J.-P.5    Kurosaki, T.6
  • 27
    • 0033945186 scopus 로고    scopus 로고
    • The role of Bruton's tyrosine kinase in B-cell development and function: A genetic perspective
    • Satterthwaite, A. B. and Witte, O. N., The role of Bruton's tyrosine kinase in B-cell development and function: a genetic perspective. Immunol. Rev. 2000. 175: 120-127.
    • (2000) Immunol. Rev. , vol.175 , pp. 120-127
    • Satterthwaite, A.B.1    Witte, O.N.2
  • 28
    • 0037087438 scopus 로고    scopus 로고
    • Macrophage effector functions controlled by Bruton's tyrosine kinase are more crucial than the cytokine balance of T cell responses for microfilarial clearance
    • Mukhopadhyay, S., Mohanty, M., Mangla, A., George, A., Bal, V., Rath, S. and Ravindran, B., Macrophage effector functions controlled by Bruton's tyrosine kinase are more crucial than the cytokine balance of T cell responses for microfilarial clearance. J. Immunol. 2002. 168: 2914-2921. (Pubitemid 34211671)
    • (2002) Journal of Immunology , vol.168 , Issue.6 , pp. 2914-2921
    • Mukhopadhyay, S.1    Mohanty, M.2    Mangla, A.3    George, A.4    Bal, V.5    Rath, S.6    Ravindran, B.7
  • 29
    • 23844518326 scopus 로고    scopus 로고
    • The Lyn tyrosine kinase differentially regulates dendritic cell generation and maturation
    • Chu, C. L. and Lowell, C. A., The Lyn tyrosine kinase differentially regulates dendritic cell generation and maturation. J. Immunol. 2005. 175: 2880-2889.
    • (2005) J. Immunol. , vol.175 , pp. 2880-2889
    • Chu, C.L.1    Lowell, C.A.2
  • 31
    • 0032494195 scopus 로고    scopus 로고
    • Independent and opposing roles for Btk and Lyn in B and myeloid signaling pathways
    • Satterthwaite, A. B., Lowell, C. A., Khan, W. N., Sideras, P., Alt, F. and Witte, O. N., Independent and opposing roles for Btk and Lyn in B and myeloid signaling pathways. J. Exp. Med. 1998. 188: 833-844.
    • (1998) J. Exp. Med. , vol.188 , pp. 833-844
    • Satterthwaite, A.B.1    Lowell, C.A.2    Khan, W.N.3    Sideras, P.4    Alt, F.5    Witte, O.N.6
  • 32
    • 0031920417 scopus 로고    scopus 로고
    • Abrogation of autoimmune disease in Lyn-deficient mice by the mutation of the Btk gene
    • Takeshita, H., Taniuchi, I., Kato, J. and Watanabe, T., Abrogation of autoimmune disease in Lyn-deficient mice by the mutation of the Btk gene. Int. Immunol. 1998. 10: 435-444.
    • (1998) Int. Immunol. , vol.10 , pp. 435-444
    • Takeshita, H.1    Taniuchi, I.2    Kato, J.3    Watanabe, T.4
  • 34
    • 33845485330 scopus 로고    scopus 로고
    • Protein array autoantibody profiles for insights into systemic lupus erythematosus and incomplete lupus syndromes
    • Li, Q. Z., Zhou, J., Wandstrat, A. E., Carr-Johnson, F., Branch, V., Karp, D. R., Mohan, C. et al., Protein array autoantibody profiles for insights into systemic lupus erythematosus and incomplete lupus syndromes. Clin. Exp. Immunol. 2007. 147: 60-70.
    • (2007) Clin. Exp. Immunol. , vol.147 , pp. 60-70
    • Li, Q.Z.1    Zhou, J.2    Wandstrat, A.E.3    Carr-Johnson, F.4    Branch, V.5    Karp, D.R.6    Mohan, C.7
  • 35
    • 0032055828 scopus 로고    scopus 로고
    • Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection
    • Cornall, R. J., Cyster, J. G., Hibbs, M. L., Dunn, A. R., Otipoby, K. L., Clark, E. A. and Goodnow, C. C., Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection. Immunity 1998. 8: 497-508.
    • (1998) Immunity , vol.8 , pp. 497-508
    • Cornall, R.J.1    Cyster, J.G.2    Hibbs, M.L.3    Dunn, A.R.4    Otipoby, K.L.5    Clark, E.A.6    Goodnow, C.C.7
  • 36
    • 60549105041 scopus 로고    scopus 로고
    • The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD41T cells
    • Dienz, O., Eaton, S. M., Bond, J. P., Neveu, W., Moquin, D., Noubade, R., Briso, E.M. et al. The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD41T cells. J. Exp. Med. 2009. 206: 69-78.
    • (2009) J. Exp. Med. , vol.206 , pp. 69-78
    • Dienz, O.1    Eaton, S.M.2    Bond, J.P.3    Neveu, W.4    Moquin, D.5    Noubade, R.6    Briso, E.M.7
  • 37
    • 46749151286 scopus 로고    scopus 로고
    • Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages
    • Nurieva, R. I., Chung, Y., Hwang, D., Yang, X. O., Kang, H. S., Ma, L., Wang, Y. H. et al., Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity 2008. 29: 138-149.
    • (2008) Immunity , vol.29 , pp. 138-149
    • Nurieva, R.I.1    Chung, Y.2    Hwang, D.3    Yang, X.O.4    Kang, H.S.5    Ma, L.6    Wang, Y.H.7
  • 38
    • 34547188748 scopus 로고    scopus 로고
    • IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
    • Zhou, L., Ivanov, I. I., Spolski, R., Min, R., Shenderov, K., Egawa, T., Levy, D. E. et al., IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat. Immunol. 2007. 8: 967-974.
    • (2007) Nat. Immunol. , vol.8 , pp. 967-974
    • Zhou, L.1    Ivanov, I.I.2    Spolski, R.3    Min, R.4    Shenderov, K.5    Egawa, T.6    Levy, D.E.7
  • 40
    • 38349178776 scopus 로고    scopus 로고
    • Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice
    • Hsu, H. C., Yang, P., Wang, J., Wu, Q., Myers, R., Chen, J., Yi, J. et al., Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice. Nat. Immunol. 2008. 9: 166-175.
    • (2008) Nat. Immunol. , vol.9 , pp. 166-175
    • Hsu, H.C.1    Yang, P.2    Wang, J.3    Wu, Q.4    Myers, R.5    Chen, J.6    Yi, J.7
  • 41
    • 33845948381 scopus 로고    scopus 로고
    • IL-6 produced by dendritic cells from lupusprone mice inhibits CD4+CD25+T cell regulatory functions
    • Wan, S., Xia, C. and Morel, L., IL-6 produced by dendritic cells from lupusprone mice inhibits CD4+CD25+T cell regulatory functions. J. Immunol. 2007. 178: 271-279.
    • (2007) J. Immunol. , vol.178 , pp. 271-279
    • Wan, S.1    Xia, C.2    Morel, L.3
  • 42
    • 18344369175 scopus 로고    scopus 로고
    • The impact of T helper and T regulatory cells on the regulation of anti-double stranded DNA B cells
    • Seo, S. J., Fields, M. L., Buckler, J. L., Reed, A. J., Mandik-Nayak, L., Nish, S. A., Noelle, R. J. et al., The impact of T helper and T regulatory cells on the regulation of anti-double stranded DNA B cells. Immunity 2002. 16: 535-546.
    • (2002) Immunity , vol.16 , pp. 535-546
    • Seo, S.J.1    Fields, M.L.2    Buckler, J.L.3    Reed, A.J.4    Mandik-Nayak, L.5    Nish, S.A.6    Noelle, R.J.7
  • 43
    • 66549091971 scopus 로고    scopus 로고
    • Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus-prone B6.Sle1.Yaa animals
    • Maeda, K., Malykhin, A., Teague-Weber, B. N., Sun, X. H., Farris, A. D. and Coggeshall, K. M., Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus-prone B6.Sle1.Yaa animals. Blood 2009. 113: 4534-4540.
    • (2009) Blood , vol.113 , pp. 4534-4540
    • Maeda, K.1    Malykhin, A.2    Teague-Weber, B.N.3    Sun, X.H.4    Farris, A.D.5    Coggeshall, K.M.6
  • 44
    • 71849086224 scopus 로고    scopus 로고
    • T cell-independent spontaneous loss of tolerance by anti-double-stranded DNA B cells in C57BL/6 mice
    • Tsao, P. Y., Jiao, J., Ji, M. Q., Cohen, L. P. and Eisenberg, R. A., T cell-independent spontaneous loss of tolerance by anti-double-stranded DNA B cells in C57BL/6 mice. J. Immunol. 2008. 181: 7770-7777.
    • (2008) J. Immunol. , vol.181 , pp. 7770-7777
    • Tsao, P.Y.1    Jiao, J.2    Ji, M.Q.3    Cohen, L.P.4    Eisenberg, R.A.5
  • 46
    • 21244498502 scopus 로고    scopus 로고
    • Cutting edge: Lowaffinity, smith antigen-specific B cells are tolerized by dendritic cells and macrophages
    • Kilmon, M. A., Rutan, J. A., Clarke, S. H. and Vilen, B. J., Cutting edge: lowaffinity, smith antigen-specific B cells are tolerized by dendritic cells and macrophages. J. Immunol. 2005. 175: 37-41.
    • (2005) J. Immunol. , vol.175 , pp. 37-41
    • Kilmon, M.A.1    Rutan, J.A.2    Clarke, S.H.3    Vilen, B.J.4
  • 47
    • 33644844972 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase is required for TLR2 and TLR4-induced TNF, but not IL-6, production
    • Horwood, N. J., Page, T. H., McDaid, J. P., Palmer, C. D., Campbell, J., Mahon, T., Brennan, F. M. et al., Bruton's tyrosine kinase is required for TLR2 and TLR4-induced TNF, but not IL-6, production. J. Immunol. 2006. 176: 3635-3641.
    • (2006) J. Immunol. , vol.176 , pp. 3635-3641
    • Horwood, N.J.1    Page, T.H.2    McDaid, J.P.3    Palmer, C.D.4    Campbell, J.5    Mahon, T.6    Brennan, F.M.7
  • 48
    • 33750840753 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase is required for TLR-induced IL-10 production
    • Schmidt, N. W., Thieu, V. T., Mann, B. A., Ahyi, A. N. and Kaplan, M. H., Bruton's tyrosine kinase is required for TLR-induced IL-10 production. J. Immunol. 2006. 177: 7203-7210.
    • (2006) J. Immunol. , vol.177 , pp. 7203-7210
    • Schmidt, N.W.1    Thieu, V.T.2    Mann, B.A.3    Ahyi, A.N.4    Kaplan, M.H.5
  • 49
    • 67349125150 scopus 로고    scopus 로고
    • Tec kinases regulate actin assembly and cytokine expression in LPS-stimulated human neutrophils via JNK activation
    • Zemans, R. L. and Arndt, P. G., Tec kinases regulate actin assembly and cytokine expression in LPS-stimulated human neutrophils via JNK activation. Cell. Immunol. 2009. 258: 90-97.
    • (2009) Cell. Immunol. , vol.258 , pp. 90-97
    • Zemans, R.L.1    Arndt, P.G.2


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