-
1
-
-
80052933197
-
Basic and therapeutic aspects of angiogenesis
-
Potente, M., Gerhardt, H., and Carmeliet, P. (2011) Basic and therapeutic aspects of angiogenesis. Cell 146, 873-887
-
(2011)
Cell
, vol.146
, pp. 873-887
-
-
Potente, M.1
Gerhardt, H.2
Carmeliet, P.3
-
2
-
-
84855995604
-
Endothelial cell-pericyte interactions stimulate basement membrane matrix assembly: Influence on vascular tube remodeling, maturation, and stabilization
-
Stratman, A. N., and Davis, G. E. (2012) Endothelial cell-pericyte interactions stimulate basement membrane matrix assembly: influence on vascular tube remodeling, maturation, and stabilization. Microsc. Microanal. 18, 68-80
-
(2012)
Microsc. Microanal.
, vol.18
, pp. 68-80
-
-
Stratman, A.N.1
Davis, G.E.2
-
3
-
-
84876297676
-
Building blood vessels in development and disease
-
Kushner, E. J., and Bautch, V. L. (2013) Building blood vessels in development and disease. Curr. Opin. Hematol. 20, 231-236
-
(2013)
Curr. Opin. Hematol.
, vol.20
, pp. 231-236
-
-
Kushner, E.J.1
Bautch, V.L.2
-
4
-
-
84896375197
-
Murine experimental autoimmune encephalomyelitis is diminished by treatment with the angiogenesis inhibitors B20-4.1.1 and angiostatin (K1-3)
-
MacMillan, C. J., Doucette, C. D., Warford, J., Furlong, S. J., Hoskin, D. W., and Easton, A. S. (2014) Murine experimental autoimmune encephalomyelitis is diminished by treatment with the angiogenesis inhibitors B20-4.1.1 and angiostatin (K1-3). PLoS ONE 9, e89770
-
(2014)
PLoS ONE
, vol.9
, pp. e89770
-
-
MacMillan, C.J.1
Doucette, C.D.2
Warford, J.3
Furlong, S.J.4
Hoskin, D.W.5
Easton, A.S.6
-
5
-
-
0017370183
-
Migrationand proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis
-
Ausprunk, D. H., and Folkman, J. (1977) Migrationand proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis. Microvasc. Res. 14, 53-65
-
(1977)
Microvasc. Res.
, vol.14
, pp. 53-65
-
-
Ausprunk, D.H.1
Folkman, J.2
-
6
-
-
84877142786
-
The tip cell concept10yearsafter: New playerstuneinforacommon theme
-
Siekmann, A. F., Affolter, M., and Belting, H. G. (2013) The tip cell concept10yearsafter: new playerstuneinforacommon theme. Exp. Cell Res. 319, 1255-1263
-
(2013)
Exp. Cell Res.
, vol.319
, pp. 1255-1263
-
-
Siekmann, A.F.1
Affolter, M.2
Belting, H.G.3
-
7
-
-
84908153461
-
Endothelialpodosome rosettes regulate vascular branching in tumour angiogenesis
-
931-938
-
Seano, G., Chiaverina, G., Gagliardi, P. A., di Blasio, L., Puliafito, A., Bouvard, C., Sessa, R., Tarone, G., Sorokin, L., Helley, D., Jain, R. K., Serini, G., Bussolino, F., and Primo, L. (2014) Endothelialpodosome rosettes regulate vascular branching in tumour angiogenesis. Nat. Cell Biol. 16, 931-941, 931-938
-
(2014)
Nat. Cell Biol.
, vol.16
, pp. 931-941
-
-
Seano, G.1
Chiaverina, G.2
Gagliardi, P.A.3
Di Blasio, L.4
Puliafito, A.5
Bouvard, C.6
Sessa, R.7
Tarone, G.8
Sorokin, L.9
Helley, D.10
Jain, R.K.11
Serini, G.12
Bussolino, F.13
Primo, L.14
-
8
-
-
33947732977
-
Angiogenesis: An organizing principle for drug discovery?
-
Folkman, J. (2007) Angiogenesis: an organizing principle for drug discovery? Nat. Rev. Drug Discov. 6, 273-286
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 273-286
-
-
Folkman, J.1
-
9
-
-
0037699955
-
Angiogenesis in health and disease
-
Carmeliet, P. (2003) Angiogenesis in health and disease. Nat. Med. 9, 653-660
-
(2003)
Nat. Med.
, vol.9
, pp. 653-660
-
-
Carmeliet, P.1
-
10
-
-
70549112270
-
The angiogenic switch in carcinogenesis. Semin
-
Baeriswyl, V., and Christofori, G. (2009) The angiogenic switch in carcinogenesis. Semin. Cancer Biol. 19, 329-337
-
(2009)
Cancer Biol.
, vol.19
, pp. 329-337
-
-
Baeriswyl, V.1
Christofori, G.2
-
11
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D., and Weinberg, R. A. (2011) Hallmarks of cancer: the next generation. Cell 144, 646-674
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
12
-
-
43249095919
-
Tumor angiogenesis
-
Kerbel, R. S. (2008) Tumor angiogenesis. N. Engl. J. Med. 358, 2039-2049
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 2039-2049
-
-
Kerbel, R.S.1
-
13
-
-
60649087564
-
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
-
Ebos, J. M., Lee, C. R., Cruz-Munoz, W., Bjarnason, G. A., Christensen, J. G., and Kerbel, R. S. (2009) Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell 15, 232-239
-
(2009)
Cancer Cell
, vol.15
, pp. 232-239
-
-
Ebos, J.M.1
Lee, C.R.2
Cruz-Munoz, W.3
Bjarnason, G.A.4
Christensen, J.G.5
Kerbel, R.S.6
-
14
-
-
84902073282
-
Induction of proline-rich tyrosine kinase 2 activation-mediated C6 glioma cell invasion after anti-vascular endothelial growth factor therapy
-
Xu, C. S., Wang, Z. F., Dai, L. M., Chu, S. H., Gong, L. L., Yang, M. H., and Li, Z. Q. (2014) Induction of proline-rich tyrosine kinase 2 activation-mediated C6 glioma cell invasion after anti-vascular endothelial growth factor therapy. J. Transl. Med. 12, 148
-
(2014)
J. Transl. Med.
, vol.12
, pp. 148
-
-
Xu, C.S.1
Wang, Z.F.2
Dai, L.M.3
Chu, S.H.4
Gong, L.L.5
Yang, M.H.6
Li, Z.Q.7
-
15
-
-
79959944026
-
Antiangiogenic therapy, hypoxia, and metastasis: Risky liaisons, or not?
-
De Bock, K., Mazzone, M., and Carmeliet, P. (2011) Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not? Nat. Rev. Clin. Oncol. 8, 393-404
-
(2011)
Nat. Rev. Clin. Oncol.
, vol.8
, pp. 393-404
-
-
De Bock, K.1
Mazzone, M.2
Carmeliet, P.3
-
16
-
-
47949099628
-
Modes of resistance to antiangiogenic therapy
-
Bergers, G., and Hanahan, D. (2008) Modes of resistance to antiangiogenic therapy. Nat. Rev. Cancer 8, 592-603
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
17
-
-
84863422466
-
Overcoming disappointing results with antiangiogenic therapy by targeting hypoxia
-
Rapisarda, A., and Melillo, G. (2012) Overcoming disappointing results with antiangiogenic therapy by targeting hypoxia. Nat. Rev. Clin. Oncol. 9, 378-390
-
(2012)
Nat. Rev. Clin. Oncol.
, vol.9
, pp. 378-390
-
-
Rapisarda, A.1
Melillo, G.2
-
18
-
-
84863283404
-
Molecular targeted therapies for cancer: Sorafenib mono-therapy and its combination with other therapies (review) [review]
-
Ibrahim, N., Yu, Y., Walsh, W. R., and Yang, J. L. (2012) Molecular targeted therapies for cancer: sorafenib mono-therapy and its combination with other therapies (review) [review]. Oncol. Rep. 27, 1303-1311
-
(2012)
Oncol. Rep.
, vol.27
, pp. 1303-1311
-
-
Ibrahim, N.1
Yu, Y.2
Walsh, W.R.3
Yang, J.L.4
-
19
-
-
0038476608
-
Benefitsoftargeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
-
Bergers, G., Song, S., Meyer-Morse, N., Bergsland, E., and Hanahan, D. (2003) Benefitsoftargeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. J. Clin. Invest. 111, 1287-1295
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 1287-1295
-
-
Bergers, G.1
Song, S.2
Meyer-Morse, N.3
Bergsland, E.4
Hanahan, D.5
-
20
-
-
77955534812
-
Double antiangiogenic protein, DAAP, targeting VEGF-A and angiopoietins in tumor angiogenesis, metastasis, and vascular leakage
-
Koh, Y. J., Kim, H. Z., Hwang, S. I., Lee, J. E., Oh, N., Jung, K., Kim, M., Kim, K. E., Kim, H., Lim, N. K., Jeon, C. J., Lee, G. M., Jeon, B. H., Nam, D. H., Sung, H. K., Nagy, A., Yoo, O. J., and Koh, G. Y. (2010) Double antiangiogenic protein, DAAP, targeting VEGF-A and angiopoietins in tumor angiogenesis, metastasis, and vascular leakage. Cancer Cell 18, 171-184
-
(2010)
Cancer Cell
, vol.18
, pp. 171-184
-
-
Koh, Y.J.1
Kim, H.Z.2
Hwang, S.I.3
Lee, J.E.4
Oh, N.5
Jung, K.6
Kim, M.7
Kim, K.E.8
Kim, H.9
Lim, N.K.10
Jeon, C.J.11
Lee, G.M.12
Jeon, B.H.13
Nam, D.H.14
Sung, H.K.15
Nagy, A.16
Yoo, O.J.17
Koh, G.Y.18
-
21
-
-
0345991242
-
Essential role of junctional adhesion molecule-1 in basic fibroblast growth factor-induced endothelial cell migration
-
Naik, M. U., Vuppalanchi, D., and Naik, U. P. (2003) Essential role of junctional adhesion molecule-1 in basic fibroblast growth factor-induced endothelial cell migration. Arterioscler. Thromb. Vasc. Biol. 23, 2165-2171
-
(2003)
Arterioscler. Thromb. Vasc. Biol.
, vol.23
, pp. 2165-2171
-
-
Naik, M.U.1
Vuppalanchi, D.2
Naik, U.P.3
-
22
-
-
21344434097
-
Antibody against junctional adhesion molecule-C inhibits angiogenesis and tumor growth
-
Lamagna, C., Hodivala-Dilke, K. M., Imhof, B. A., and Aurrand-Lions, M. (2005) Antibody against junctional adhesion molecule-C inhibits angiogenesis and tumor growth. Cancer Res. 65, 5703-5710
-
(2005)
Cancer Res.
, vol.65
, pp. 5703-5710
-
-
Lamagna, C.1
Hodivala-Dilke, K.M.2
Imhof, B.A.3
Aurrand-Lions, M.4
-
23
-
-
33751546663
-
Junctional adhesion molecule-C regulates vascular endothelial permeability by modulating VE-cadherin-mediated cell-cell contacts
-
Orlova, V. V., Economopoulou, M., Lupu, F., Santoso, S., and Chavakis, T. (2006) Junctional adhesion molecule-C regulates vascular endothelial permeability by modulating VE-cadherin-mediated cell-cell contacts. J. Exp. Med. 203, 2703-2714
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2703-2714
-
-
Orlova, V.V.1
Economopoulou, M.2
Lupu, F.3
Santoso, S.4
Chavakis, T.5
-
24
-
-
34249650761
-
The role of junctional adhesion molecules in vascular inflammation
-
Weber, C., Fraemohs, L., and Dejana, E. (2007) The role of junctional adhesion molecules in vascular inflammation. Nat. Rev. Immunol. 7, 467-477
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 467-477
-
-
Weber, C.1
Fraemohs, L.2
Dejana, E.3
-
25
-
-
0034705379
-
Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells
-
Palmeri, D., van Zante, A., Huang, C. C., Hemmerich, S., and Rosen, S. D. (2000) Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells. J. Biol. Chem. 275, 19139-19145
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 19139-19145
-
-
Palmeri, D.1
Van Zante, A.2
Huang, C.C.3
Hemmerich, S.4
Rosen, S.D.5
-
26
-
-
0037083419
-
Vascular endothelial-junctional adhesion molecule (VE-JAM)/JAM 2 interacts with T, NK, and dendritic cells through JAM 3
-
Liang, T. W., Chiu, H. H., Gurney, A., Sidle, A., Tumas, D. B., Schow, P., Foster, J., Klassen, T., Dennis, K., DeMarco, R. A., Pham, T., Frantz, G., and Fong, S. (2002) Vascular endothelial-junctional adhesion molecule (VE-JAM)/JAM 2 interacts with T, NK, and dendritic cells through JAM 3. J. Immunol. 168, 1618-1626
-
(2002)
J. Immunol.
, vol.168
, pp. 1618-1626
-
-
Liang, T.W.1
Chiu, H.H.2
Gurney, A.3
Sidle, A.4
Tumas, D.B.5
Schow, P.6
Foster, J.7
Klassen, T.8
Dennis, K.9
DeMarco, R.A.10
Pham, T.11
Frantz, G.12
Fong, S.13
-
27
-
-
33644795491
-
Junctional adhesion molecules (JAM)-B and-C contribute to leukocyte extravasation to the skinandmediatecutaneous inflammation
-
Ludwig, R. J., Zollner, T. M., Santoso, S., Hardt, K., Gille, J., Baatz, H., Johann, P. S., Pfeffer, J., Radeke, H. H., Schön, M. P., Kaufmann, R., Boehncke, W. H., and Podda, M. (2005) Junctional adhesion molecules (JAM)-B and-C contribute to leukocyte extravasation to the skinandmediatecutaneous inflammation. J. Invest. Dermatol. 125, 969-976
-
(2005)
J. Invest. Dermatol.
, vol.125
, pp. 969-976
-
-
Ludwig, R.J.1
Zollner, T.M.2
Santoso, S.3
Hardt, K.4
Gille, J.5
Baatz, H.6
Johann, P.S.7
Pfeffer, J.8
Radeke, H.H.9
Schön, M.P.10
Kaufmann, R.11
Boehncke, W.H.12
Podda, M.13
-
28
-
-
84872589087
-
Homing of human B cells to lymphoid organs and B-cell lymphoma engraftment are controlled by cell adhesion molecule JAM-C
-
Doñate, C., Ody, C., McKee, T., Ruault-Jungblut, S., Fischer, N., Ropraz, P., Imhof, B. A., and Matthes, T. (2013) Homing of human B cells to lymphoid organs and B-cell lymphoma engraftment are controlled by cell adhesion molecule JAM-C. Cancer Res. 73, 640-651
-
(2013)
Cancer Res.
, vol.73
, pp. 640-651
-
-
Doñate, C.1
Ody, C.2
McKee, T.3
Ruault-Jungblut, S.4
Fischer, N.5
Ropraz, P.6
Imhof, B.A.7
Matthes, T.8
-
29
-
-
80055078599
-
JAM-B regulates maintenance of hematopoietic stem cells in the bone marrow
-
Arcangeli, M. L., Frontera, V., Bardin, F., Obrados, E., Adams, S., Chabannon, C., Schiff, C., Mancini, S. J., Adams, R. H., and Aurrand-Lions, M. (2011) JAM-B regulates maintenance of hematopoietic stem cells in the bone marrow. Blood 118, 4609-4619
-
(2011)
Blood
, vol.118
, pp. 4609-4619
-
-
Arcangeli, M.L.1
Frontera, V.2
Bardin, F.3
Obrados, E.4
Adams, S.5
Chabannon, C.6
Schiff, C.7
Mancini, S.J.8
Adams, R.H.9
Aurrand-Lions, M.10
-
30
-
-
84868534744
-
The junctional adhesion molecule-B regulates JAM-C-dependent melanoma cell metastasis
-
Arcangeli, M. L., Frontera, V., Bardin, F., Thomassin, J., Chetaille, B., Adams, S., Adams, R. H., and Aurrand-Lions, M. (2012) The junctional adhesion molecule-B regulates JAM-C-dependent melanoma cell metastasis. FEBS Lett. 586, 4046-4051
-
(2012)
FEBS Lett.
, vol.586
, pp. 4046-4051
-
-
Arcangeli, M.L.1
Frontera, V.2
Bardin, F.3
Thomassin, J.4
Chetaille, B.5
Adams, S.6
Adams, R.H.7
Aurrand-Lions, M.8
-
31
-
-
77954684182
-
Endothelial lumen signaling complexes control 3D matrix-specific tubulogenesis through interdependent Cdc42- and MT1-MMP-mediated events
-
Sacharidou, A., Koh, W., Stratman, A. N., Mayo, A. M., Fisher, K. E., and Davis, G. E. (2010) Endothelial lumen signaling complexes control 3D matrix-specific tubulogenesis through interdependent Cdc42- and MT1-MMP-mediated events. Blood 115, 5259-5269
-
(2010)
Blood
, vol.115
, pp. 5259-5269
-
-
Sacharidou, A.1
Koh, W.2
Stratman, A.N.3
Mayo, A.M.4
Fisher, K.E.5
Davis, G.E.6
-
32
-
-
77953457835
-
Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome
-
Reynolds, L. E., Watson, A. R., Baker, M., Jones, T. A., D'Amico, G., Robinson, S. D., Joffre, C., Garrido-Urbani, S., Rodriguez-Manzaneque, J. C., Martino-Echarri, E., Aurrand-Lions, M., Sheer, D., Dagna-Bricarelli, F., Nizetic, D., McCabe, C. J., Turnell, A. S., Kermorgant, S., Imhof, B. A., Adams, R., Fisher, E. M., Tybulewicz, V. L., Hart, I. R., and Hodivala-Dilke, K. M. (2010) Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome. Nature 465, 813-817
-
(2010)
Nature
, vol.465
, pp. 813-817
-
-
Reynolds, L.E.1
Watson, A.R.2
Baker, M.3
Jones, T.A.4
D'Amico, G.5
Robinson, S.D.6
Joffre, C.7
Garrido-Urbani, S.8
Rodriguez-Manzaneque, J.C.9
Martino-Echarri, E.10
Aurrand-Lions, M.11
Sheer, D.12
Dagna-Bricarelli, F.13
Nizetic, D.14
McCabe, C.J.15
Turnell, A.S.16
Kermorgant, S.17
Imhof, B.A.18
Adams, R.19
Fisher, E.M.20
Tybulewicz, V.L.21
Hart, I.R.22
Hodivala-Dilke, K.M.23
more..
-
33
-
-
79951539813
-
Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARa mediated mechanism
-
Garrido-Urbani, S., Jemelin, S., Deffert, C., Carnesecchi, S., Basset, O., Szyndralewiez, C., Heitz, F., Page, P., Montet, X., Michalik, L., Arbiser, J., Rüegg, C., Krause, K. H., and Imhof, B. A. (2011) Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARa mediated mechanism. PLoS ONE 6, e14665
-
(2011)
PLoS ONE
, vol.6
, pp. e14665
-
-
Garrido-Urbani, S.1
Jemelin, S.2
Deffert, C.3
Carnesecchi, S.4
Basset, O.5
Szyndralewiez, C.6
Heitz, F.7
Page, P.8
Montet, X.9
Michalik, L.10
Arbiser, J.11
Rüegg, C.12
Krause, K.H.13
Imhof, B.A.14
-
34
-
-
84861151846
-
Use of the mouse aortic ring assay to study angiogenesis
-
Baker, M., Robinson, S. D., Lechertier, T., Barber, P. R., Tavora, B., D'Amico, G., Jones, D. T., Vojnovic, B., and Hodivala-Dilke, K. (2011) Use of the mouse aortic ring assay to study angiogenesis. Nat. Protoc. 7, 89-104
-
(2011)
Nat. Protoc.
, vol.7
, pp. 89-104
-
-
Baker, M.1
Robinson, S.D.2
Lechertier, T.3
Barber, P.R.4
Tavora, B.5
D'Amico, G.6
Jones, D.T.7
Vojnovic, B.8
Hodivala-Dilke, K.9
-
35
-
-
0030701960
-
Halting angiogenesis suppresses carcinomacell invasion
-
Skobe, M., Rockwell, P., Goldstein, N., Vosseler, S., and Fusenig, N. E. (1997) Halting angiogenesis suppresses carcinomacell invasion. Nat. Med. 3, 1222-1227
-
(1997)
Nat. Med.
, vol.3
, pp. 1222-1227
-
-
Skobe, M.1
Rockwell, P.2
Goldstein, N.3
Vosseler, S.4
Fusenig, N.E.5
-
36
-
-
0034490621
-
PECAM-1/CD31 trans-homophilic binding at the intercellular junctions is independent of its cytoplasmic domain; evidence for heterophilic interaction with integrin alphavbeta3 in Cis
-
Wong, C. W., Wiedle, G., Ballestrem, C., Wehrle-Haller, B., Etteldorf, S., Bruckner, M., Engelhardt, B., Gisler, R. H., and Imhof, B. A. (2000) PECAM-1/CD31 trans-homophilic binding at the intercellular junctions is independent of its cytoplasmic domain; evidence for heterophilic interaction with integrin alphavbeta3 in Cis. Mol. Biol. Cell 11, 3109-3121
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 3109-3121
-
-
Wong, C.W.1
Wiedle, G.2
Ballestrem, C.3
Wehrle-Haller, B.4
Etteldorf, S.5
Bruckner, M.6
Engelhardt, B.7
Gisler, R.H.8
Imhof, B.A.9
-
37
-
-
0022881517
-
A monoclonal antibody against alpha-smooth muscle actin: A new probe for smooth muscle differentiation
-
Skalli, O., Ropraz, P., Trzeciak, A., Benzonana, G., Gillessen, D., and Gabbiani, G. (1986) A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation. J. Cell Biol. 103, 2787-2796
-
(1986)
J. Cell Biol.
, vol.103
, pp. 2787-2796
-
-
Skalli, O.1
Ropraz, P.2
Trzeciak, A.3
Benzonana, G.4
Gillessen, D.5
Gabbiani, G.6
-
38
-
-
80052211625
-
Angiopoietin-1 and -2 exert antagonistic functions in tumor angiogenesis, yet both induce lymphangiogenesis
-
Fagiani, E., Lorentz, P., Kopfstein, L., and Christofori, G. (2011) Angiopoietin-1 and -2 exert antagonistic functions in tumor angiogenesis, yet both induce lymphangiogenesis. Cancer Res. 71, 5717-5727
-
(2011)
Cancer Res.
, vol.71
, pp. 5717-5727
-
-
Fagiani, E.1
Lorentz, P.2
Kopfstein, L.3
Christofori, G.4
-
39
-
-
2642557100
-
Haemangiomas are formed by cells expressing high levels of alphavbeta3 integrin and lacking acetylated LDL uptake
-
Aurrand-Lions, M., Johnson-Leger, C., Pepper, M. S., and Imhof, B. A. (2004) Haemangiomas are formed by cells expressing high levels of alphavbeta3 integrin and lacking acetylated LDL uptake. J. Pathol. 203, 700-709
-
(2004)
J. Pathol.
, vol.203
, pp. 700-709
-
-
Aurrand-Lions, M.1
Johnson-Leger, C.2
Pepper, M.S.3
Imhof, B.A.4
-
40
-
-
0031870832
-
Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy
-
Witte, L., Hicklin, D. J., Zhu, Z., Pytowski, B., Kotanides, H., Rockwell, P., and Böhlen, P. (1998) Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy. Cancer Metastasis Rev. 17, 155-161
-
(1998)
Cancer Metastasis Rev.
, vol.17
, pp. 155-161
-
-
Witte, L.1
Hicklin, D.J.2
Zhu, Z.3
Pytowski, B.4
Kotanides, H.5
Rockwell, P.6
Böhlen, P.7
-
41
-
-
84877296919
-
The VEGF pathway in cancer and disease: Responses, resistance, and the path forward
-
Kieran, M. W., Kalluri, R., and Cho, Y. J. (2012) The VEGF pathway in cancer and disease: responses, resistance, and the path forward. Cold Spring Harb. Perspect. Med. 2, a006593
-
(2012)
Cold Spring Harb. Perspect. Med.
, vol.2
, pp. a006593
-
-
Kieran, M.W.1
Kalluri, R.2
Cho, Y.J.3
-
42
-
-
84872553104
-
VEGFA and tumour angiogenesis
-
Claesson-Welsh, L., and Welsh, M. (2013) VEGFA and tumour angiogenesis. J. Intern. Med. 273, 114-127
-
(2013)
J. Intern. Med.
, vol.273
, pp. 114-127
-
-
Claesson-Welsh, L.1
Welsh, M.2
-
43
-
-
84899677468
-
Junctional adhesion molecule-A suppresses platelet integrin a IIb b3 signaling by recruiting Csk to the integrin-c-Src complex
-
Naik, M. U., Caplan, J. L., and Naik, U. P. (2014) Junctional adhesion molecule-A suppresses platelet integrin a IIb b3 signaling by recruiting Csk to the integrin-c-Src complex. Blood 123, 1393-1402
-
(2014)
Blood
, vol.123
, pp. 1393-1402
-
-
Naik, M.U.1
Caplan, J.L.2
Naik, U.P.3
-
44
-
-
84890433094
-
MicroRNA-223 antagonizes angiogenesis by targeting b1 integrin and preventing growth factor signaling in endothelial cells
-
Shi, L., Fisslthaler, B., Zippel, N., Fromel, T., Hu, J., Elgheznawy, A., Heide, H., Popp, R, and Fleming, I. (2013) MicroRNA-223 antagonizes angiogenesis by targeting b1 integrin and preventing growth factor signaling in endothelial cells. Circ. Res. 113, 1320-1330
-
(2013)
Circ. Res.
, vol.113
, pp. 1320-1330
-
-
Shi, L.1
Fisslthaler, B.2
Zippel, N.3
Fromel, T.4
Hu, J.5
Elgheznawy, A.6
Heide, H.7
Popp, R.8
Fleming, I.9
-
45
-
-
0034744186
-
Superactivation of integrin alphavbeta3 by low antagonist concentrations
-
Legler, D. F., Wiedle, G., Ross, F. P., and Imhof, B. A (2001) Superactivation of integrin alphavbeta3 by low antagonist concentrations. J. CellSci. 114, 1545-1553
-
(2001)
J. CellSci.
, vol.114
, pp. 1545-1553
-
-
Legler, D.F.1
Wiedle, G.2
Ross, F.P.3
Imhof, B.A.4
-
46
-
-
0036023438
-
Anti-vascular endothelial growth factor receptor 2 antibody reduces tumorigenicity and metastasis in orthotopic prostate cancer xenografts via induction of endothelial cell apoptosis and reduction of endothelial cell matrix metalloproteinase type 9 production
-
Sweeney, P., Karashima, T., Kim, S. J., Kedar, D., Mian, B., Huang, S., Baker, C., Fan, Z., Hicklin, D. J., Pettaway, C. A, and Dinney, C. P. (2002) Anti-vascular endothelial growth factor receptor 2 antibody reduces tumorigenicity and metastasis in orthotopic prostate cancer xenografts via induction of endothelial cell apoptosis and reduction of endothelial cell matrix metalloproteinase type 9 production. Clin. Cancer Res. 8, 2714-2724
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 2714-2724
-
-
Sweeney, P.1
Karashima, T.2
Kim, S.J.3
Kedar, D.4
Mian, B.5
Huang, S.6
Baker, C.7
Fan, Z.8
Hicklin, D.J.9
Pettaway, C.A.10
Dinney, C.P.11
-
47
-
-
84868595744
-
Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases
-
Kodack, D. P., Chung, E., Yamashita, H., Incio, J., Duyverman, A M., Song, Y., Farrar, C. T., Huang, Y., Ager, E., Kamoun, W., Goel, S., Snuderl, M., Lussiez, A., Hiddingh, L., Mahmood, S., Tannous, B. A., Eichler, A. F., Fukumura, D., Engelman, J. A, and Jain, R. K. (2012) Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases. Proc. Natl. Acad. Sci. USA 109, E3119-E3127
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. E3119-E3127
-
-
Kodack, D.P.1
Chung, E.2
Yamashita, H.3
Incio, J.4
Duyverman, A.M.5
Song, Y.6
Farrar, C.T.7
Huang, Y.8
Ager, E.9
Kamoun, W.10
Goel, S.11
Snuderl, M.12
Lussiez, A.13
Hiddingh, L.14
Mahmood, S.15
Tannous, B.A.16
Eichler, A.F.17
Fukumura, D.18
Engelman, J.A.19
Jain, R.K.20
more..
-
48
-
-
0021888904
-
Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes
-
Hanahan, D. (1985) Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes. Nature 315, 115-122
-
(1985)
Nature
, vol.315
, pp. 115-122
-
-
Hanahan, D.1
-
49
-
-
84868301370
-
"Sprouting angiogenesis", a reappraisal
-
Ribatti, D., and Crivellato, E. (2012) "Sprouting angiogenesis", a reappraisal. Dev. Biol. 372, 157-165
-
(2012)
Dev. Biol.
, vol.372
, pp. 157-165
-
-
Ribatti, D.1
Crivellato, E.2
-
50
-
-
84871392869
-
Targeting olfactomedin-like 3 inhibits tumor growth by impairing angiogenesis and pericyte coverage
-
Miljkovic-Licina, M., Hammel, P., Garrido-Urbani, S., Lee, B. P., Meguenani, M., Chaabane, C., Bochaton-Piallat, M. L., and Imhof, B. A (2012) Targeting olfactomedin-like 3 inhibits tumor growth by impairing angiogenesis and pericyte coverage. Mol. Cancer Ther. 11, 2588-2599
-
(2012)
Mol. Cancer Ther.
, vol.11
, pp. 2588-2599
-
-
Miljkovic-Licina, M.1
Hammel, P.2
Garrido-Urbani, S.3
Lee, B.P.4
Meguenani, M.5
Chaabane, C.6
Bochaton-Piallat, M.L.7
Imhof, B.A.8
-
51
-
-
69949112052
-
Junctional adhesion molecule (JAM)-B supports lymphocyte rolling and adhesion through interaction with alpha4beta1 integrin
-
Ludwig, R J., Hardt, K., Hatting, M., Bistrian, R., Diehl, S., Radeke, H. H., Podda, M., Schon, M. P., Kaufmann, R., Henschler, R., Pfeilschifter, J. M., Santoso, S., and Boehncke, W. H. (2009) Junctional adhesion molecule (JAM)-B supports lymphocyte rolling and adhesion through interaction with alpha4beta1 integrin. Immunology 128, 196-205
-
(2009)
Immunology
, vol.128
, pp. 196-205
-
-
Ludwig, R.J.1
Hardt, K.2
Hatting, M.3
Bistrian, R.4
Diehl, S.5
Radeke, H.H.6
Podda, M.7
Schon, M.P.8
Kaufmann, R.9
Henschler, R.10
Pfeilschifter, J.M.11
Santoso, S.12
Boehncke, W.H.13
-
52
-
-
0242405617
-
Endothelial-pericyte interactions in angiogenesis
-
Gerhardt, H., and Betsholtz, C. (2003) Endothelial-pericyte interactions in angiogenesis. Cell Tissue Res. 314, 15-23
-
(2003)
Cell Tissue Res.
, vol.314
, pp. 15-23
-
-
Gerhardt, H.1
Betsholtz, C.2
-
53
-
-
0036124520
-
Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors
-
Morikawa, S., Baluk, P., Kaidoh, T., Haskell, A., Jain, R. K., and McDonald, D. M. (2002) Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors. Am. J. Pathol. 160, 985-1000
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 985-1000
-
-
Morikawa, S.1
Baluk, P.2
Kaidoh, T.3
Haskell, A.4
Jain, R.K.5
McDonald, D.M.6
-
54
-
-
0030745259
-
Molecular mechanisms of blood vessel formation
-
Bussolino, F., Mantovani, A., and Persico, G. (1997) Molecular mechanisms of blood vessel formation. Trends Biochem. Sci. 22, 251-256
-
(1997)
Trends Biochem. Sci.
, vol.22
, pp. 251-256
-
-
Bussolino, F.1
Mantovani, A.2
Persico, G.3
-
55
-
-
71449088789
-
MT1-MMP- and Cdc42-dependent signaling co-regulate cell invasion and tunnel formation in 3D collagen matrices
-
Fisher, K. E., Sacharidou, A., Stratman, A. N., Mayo, A. M., Fisher, S. B., Mahan, R. D., Davis, M. J., and Davis, G. E. (2009) MT1-MMP- and Cdc42-dependent signaling co-regulate cell invasion and tunnel formation in 3D collagen matrices. J. Cell Sci. 122, 4558-4569
-
(2009)
J. Cell Sci.
, vol.122
, pp. 4558-4569
-
-
Fisher, K.E.1
Sacharidou, A.2
Stratman, A.N.3
Mayo, A.M.4
Fisher, S.B.5
Mahan, R.D.6
Davis, M.J.7
Davis, G.E.8
-
56
-
-
84872437118
-
Involvement of P38MAPK in human corneal endothelial cell migration induced by TGF-b (2)
-
Joko, T., Shiraishi, A., Akune, Y., Tokumaru, S., Kobayashi, T., Miyata, K., and Ohashi, Y. (2013) Involvement of P38MAPK in human corneal endothelial cell migration induced by TGF-b (2). Exp. Eye Res. 108, 23-32
-
(2013)
Exp. Eye Res.
, vol.108
, pp. 23-32
-
-
Joko, T.1
Shiraishi, A.2
Akune, Y.3
Tokumaru, S.4
Kobayashi, T.5
Miyata, K.6
Ohashi, Y.7
-
57
-
-
0033710778
-
The RasGAP-binding protein p62dok is a mediator of inhibitory FcgammaRIIB signals in B cells
-
Tamir, I., Stolpa, J. C., Helgason, C. D., Nakamura, K., Bruhns, P., Daeron, M., and Cambier, J. C. (2000) The RasGAP-binding protein p62dok is a mediator of inhibitory FcgammaRIIB signals in B cells. Immunity 12, 347-358
-
(2000)
Immunity
, vol.12
, pp. 347-358
-
-
Tamir, I.1
Stolpa, J.C.2
Helgason, C.D.3
Nakamura, K.4
Bruhns, P.5
Daeron, M.6
Cambier, J.C.7
-
58
-
-
84870244259
-
Bevacizumab plus oxaliplatinbased chemotherapy as adjuvant treatment for colon cancer (AVANT): A phase 3 randomised controlled trial
-
De Gramont, A., Van Cutsem, E., Schmoll, H. J., Tabernero, J., Clarke, S., Moore, M. J., Cunningham, D., Cartwright, T. H., Hecht, J. R., Rivera, F., Im, S. A., Bodoky, G., Salazar, R., Maindrault-Goebel, F., Shacham-Shmueli, E., Bajetta, E., Makrutzki, M., Shang, A., André, T., and Hoff, P. M. (2012) Bevacizumab plus oxaliplatinbased chemotherapy as adjuvant treatment for colon cancer (AVANT): a phase 3 randomised controlled trial. Lancet Oncol. 13, 1225-1233
-
(2012)
Lancet Oncol.
, vol.13
, pp. 1225-1233
-
-
De Gramont, A.1
Van Cutsem, E.2
Schmoll, H.J.3
Tabernero, J.4
Clarke, S.5
Moore, M.J.6
Cunningham, D.7
Cartwright, T.H.8
Hecht, J.R.9
Rivera, F.10
Im, S.A.11
Bodoky, G.12
Salazar, R.13
Maindrault-Goebel, F.14
Shacham-Shmueli, E.15
Bajetta, E.16
Makrutzki, M.17
Shang, A.18
André, T.19
Hoff, P.M.20
more..
-
59
-
-
84872321095
-
Phase I study of bevacizumab combined with irinotecan and S-1 as second-line chemotherapy in patients with advanced colorectal cancer
-
Kusaba, H., Esaki, T., Kishimoto, J., Uchino, K., Arita, S., Kumagai, H., Mitsugi, K., Akashi, K., and Baba, E. (2013) Phase I study of bevacizumab combined with irinotecan and S-1 as second-line chemotherapy in patients with advanced colorectal cancer. Cancer Chemother. Pharmacol. 71, 29-34
-
(2013)
Cancer Chemother. Pharmacol.
, vol.71
, pp. 29-34
-
-
Kusaba, H.1
Esaki, T.2
Kishimoto, J.3
Uchino, K.4
Arita, S.5
Kumagai, H.6
Mitsugi, K.7
Akashi, K.8
Baba, E.9
-
60
-
-
26644471951
-
Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
-
Casanovas, O., Hicklin, D. J., Bergers, G., and Hanahan, D. (2005) Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors. Cancer Cell 8, 299-309
-
(2005)
Cancer Cell
, vol.8
, pp. 299-309
-
-
Casanovas, O.1
Hicklin, D.J.2
Bergers, G.3
Hanahan, D.4
-
61
-
-
83355166920
-
Compensatory regulation of dopamine after ablation of the tyrosine hydroxylase gene in the nigrostriatal projection
-
Tokuoka, H., Muramatsu, S., Sumi-Ichinose, C., Sakane, H., Kojima, M., Aso, Y., Nomura, T., Metzger, D., and Ichinose, H. (2011) Compensatory regulation of dopamine after ablation of the tyrosine hydroxylase gene in the nigrostriatal projection. J. Biol. Chem. 286, 43549-43558
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 43549-43558
-
-
Tokuoka, H.1
Muramatsu, S.2
Sumi-Ichinose, C.3
Sakane, H.4
Kojima, M.5
Aso, Y.6
Nomura, T.7
Metzger, D.8
Ichinose, H.9
-
62
-
-
79960622296
-
Effects of BCL-2 suppression by antisense oligonucleotides on additional regulators of apoptosis compensatory change in non-targeted protein expression
-
Rubenstein, M., Hollowell, C. M., and Guinan, P. (2011) Effects of BCL-2 suppression by antisense oligonucleotides on additional regulators of apoptosis compensatory change in non-targeted protein expression. In Vivo 25, 725-732
-
(2011)
Vivo
, vol.25
, pp. 725-732
-
-
Rubenstein, M.1
Hollowell, C.M.2
Guinan, P.3
-
63
-
-
84908135486
-
The antioxidant paradox: What are antioxidants and how should they be used in a therapeutic context for cancer
-
Bonner, M. Y., and Arbiser, J. L. (2014) The antioxidant paradox: what are antioxidants and how should they be used in a therapeutic context for cancer. Future Med. Chem. 6, 1413-1422
-
(2014)
Future Med. Chem.
, vol.6
, pp. 1413-1422
-
-
Bonner, M.Y.1
Arbiser, J.L.2
-
64
-
-
84918500125
-
Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells
-
Mochin, M. T., Underwood, K. F., Cooper, B., McLenithan, J. C., Pierce, A. D., Nalvarte, C., Arbiser, J., Karlsson, A. I., Moise, A. R., Moskovitz, J., and Passaniti, A. (2015) Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells. Microvasc. Res. 97, 55-64
-
(2015)
Microvasc. Res.
, vol.97
, pp. 55-64
-
-
Mochin, M.T.1
Underwood, K.F.2
Cooper, B.3
McLenithan, J.C.4
Pierce, A.D.5
Nalvarte, C.6
Arbiser, J.7
Karlsson, A.I.8
Moise, A.R.9
Moskovitz, J.10
Passaniti, A.11
|