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Volumn 7, Issue 6, 2007, Pages 467-477

The role of junctional adhesion molecules in vascular inflammation

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; BETA2 INTEGRIN; FIBROBLAST GROWTH FACTOR 2; GAMMA INTERFERON; GUANOSINE TRIPHOSPHATASE; JUNCTIONAL ADHESION MOLECULE 4; JUNCTIONAL ADHESION MOLECULE A; JUNCTIONAL ADHESION MOLECULE B; JUNCTIONAL ADHESION MOLECULE C; LYMPHOCYTE ANTIGEN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; PROTEIN AMICA1; RAP1 PROTEIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

EID: 34249650761     PISSN: 14741733     EISSN: None     Source Type: Journal    
DOI: 10.1038/nri2096     Document Type: Review
Times cited : (421)

References (81)
  • 1
    • 0038180539 scopus 로고    scopus 로고
    • Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response
    • Muller, W. A. Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response. Trends Immunol. 24, 327-334 (2003).
    • (2003) Trends Immunol , vol.24 , pp. 327-334
    • Muller, W.A.1
  • 2
    • 2942532639 scopus 로고    scopus 로고
    • Adhesion mechanisms regulating the migration of monocytes
    • Imhof, B. A. & Aurrand-Lions, M. Adhesion mechanisms regulating the migration of monocytes. Nature Rev. Immunol. 4, 432-444 (2004).
    • (2004) Nature Rev. Immunol , vol.4 , pp. 432-444
    • Imhof, B.A.1    Aurrand-Lions, M.2
  • 3
    • 0037280317 scopus 로고    scopus 로고
    • Novel mechanistic concepts for the control of leukocyte transmigration: Specialization of integrins, chemokines, and junctional molecules
    • Weber, C. Novel mechanistic concepts for the control of leukocyte transmigration: specialization of integrins, chemokines, and junctional molecules. J. Mol. Med. 81, 4-19 (2003).
    • (2003) J. Mol. Med , vol.81 , pp. 4-19
    • Weber, C.1
  • 4
    • 0141644213 scopus 로고    scopus 로고
    • The JAM family of junctional adhesion molecules
    • Bazzoni, G. The JAM family of junctional adhesion molecules. Curr. Opin. Cell Biol. 15, 525-530 (2003).
    • (2003) Curr. Opin. Cell Biol , vol.15 , pp. 525-530
    • Bazzoni, G.1
  • 5
    • 2642614521 scopus 로고    scopus 로고
    • Martin-Padura, I. et al. Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J. Cell Biol. 142, 117-127 (1998). This paper reports the identification of JAM-A at intercellular junctions and its involvement in mononuclear transmigration.
    • Martin-Padura, I. et al. Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J. Cell Biol. 142, 117-127 (1998). This paper reports the identification of JAM-A at intercellular junctions and its involvement in mononuclear transmigration.
  • 6
    • 0033233421 scopus 로고    scopus 로고
    • Identification and characterisation of human junctional adhesion molecule (JAM)
    • Williams, L. A., Martin-Padura, I., Dejana, E., Hogg, N. & Simmons, D. L. Identification and characterisation of human junctional adhesion molecule (JAM). Mol. Immunol. 36, 1175-1188 (1999).
    • (1999) Mol. Immunol , vol.36 , pp. 1175-1188
    • Williams, L.A.1    Martin-Padura, I.2    Dejana, E.3    Hogg, N.4    Simmons, D.L.5
  • 7
    • 0034705379 scopus 로고    scopus 로고
    • Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells
    • Palmeri, D., van Zante, A., Huang, C. C., Hemmerich, S. & Rosen, S. D. Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells. J. Biol. Chem. 275, 19139-19145 (2000).
    • (2000) J. Biol. Chem , vol.275 , pp. 19139-19145
    • Palmeri, D.1    van Zante, A.2    Huang, C.C.3    Hemmerich, S.4    Rosen, S.D.5
  • 8
    • 0034602185 scopus 로고    scopus 로고
    • A novel protein with homology to the junctional adhesion molecule. Characterization of leukocyte interactions
    • Cunningham, S. A. et al. A novel protein with homology to the junctional adhesion molecule. Characterization of leukocyte interactions. J. Biol. Chem. 275, 34750-34756 (2000).
    • (2000) J. Biol. Chem , vol.275 , pp. 34750-34756
    • Cunningham, S.A.1
  • 9
    • 0035951873 scopus 로고    scopus 로고
    • JAM-2, a novel immunoglobulin superfamily molecule, expressed by endothelial and lymphatic cells
    • Aurrand-Lions, M., Duncan, L., Ballestrem, C. & Imhof, B. A. JAM-2, a novel immunoglobulin superfamily molecule, expressed by endothelial and lymphatic cells. J. Biol. Chem. 276, 2733-2741 (2001).
    • (2001) J. Biol. Chem , vol.276 , pp. 2733-2741
    • Aurrand-Lions, M.1    Duncan, L.2    Ballestrem, C.3    Imhof, B.A.4
  • 10
    • 0035824527 scopus 로고    scopus 로고
    • Cloning of human junctional adhesion molecule 3 (JAM3) and its identification as the JAM2 counter-receptor
    • Arrate, M. P., Rodriguez, J. M., Tran, T. M., Brock, T. A. & Cunningham, S. A. Cloning of human junctional adhesion molecule 3 (JAM3) and its identification as the JAM2 counter-receptor. J. Biol. Chem. 276, 45826-45832 (2001).
    • (2001) J. Biol. Chem , vol.276 , pp. 45826-45832
    • Arrate, M.P.1    Rodriguez, J.M.2    Tran, T.M.3    Brock, T.A.4    Cunningham, S.A.5
  • 11
    • 0037083419 scopus 로고    scopus 로고
    • Liang, T. W. et al. Vascular endothelial-junctional adhesion molecule (VE-JAM)/JAM 2 interacts with T, NK, and dendritic cells through JAM3. J. Immunol. 168, 1618-1626 (2002).
    • Liang, T. W. et al. Vascular endothelial-junctional adhesion molecule (VE-JAM)/JAM 2 interacts with T, NK, and dendritic cells through JAM3. J. Immunol. 168, 1618-1626 (2002).
  • 12
    • 0037641234 scopus 로고    scopus 로고
    • JAM4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1
    • Hirabayashi, S. et al. JAM4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1. Mol. Cell. Biol. 23, 4267-4282 (2003).
    • (2003) Mol. Cell. Biol , vol.23 , pp. 4267-4282
    • Hirabayashi, S.1
  • 13
    • 0142245587 scopus 로고    scopus 로고
    • JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cells
    • Moog-Lutz, C. et al. JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cells. Blood 102, 3371-3378 (2003).
    • (2003) Blood , vol.102 , pp. 3371-3378
    • Moog-Lutz, C.1
  • 14
    • 17944374159 scopus 로고    scopus 로고
    • X-ray structure of junctional adhesion molecule: Structural basis for homophilic adhesion via a novel dimerization motif
    • Kostrewa, D. et al. X-ray structure of junctional adhesion molecule: structural basis for homophilic adhesion via a novel dimerization motif. EMBO J. 20, 4391-4398 (2001).
    • (2001) EMBO J , vol.20 , pp. 4391-4398
    • Kostrewa, D.1
  • 15
    • 0038185285 scopus 로고    scopus 로고
    • Crystal structure of human junctional adhesion molecule 1: Implications for reovirus binding
    • Prota, A. E. et al. Crystal structure of human junctional adhesion molecule 1: implications for reovirus binding. Proc. Natl Acad. Sci. USA 100, 5366-5371 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 5366-5371
    • Prota, A.E.1
  • 16
    • 0033902942 scopus 로고    scopus 로고
    • Human junction adhesion molecule regulates tight junction resealing in epithelia
    • Liu, Y. et al. Human junction adhesion molecule regulates tight junction resealing in epithelia. J. Cell Sci. 113 2363-2374 (2000).
    • (2000) J. Cell Sci , vol.113 , pp. 2363-2374
    • Liu, Y.1
  • 17
    • 0036785376 scopus 로고    scopus 로고
    • Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration
    • Johnson-Leger, C. A., Aurrand-Lions, M., Beltraminelli, N., Fasel, N. & Imhof, B. A. Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration. Blood 100, 2479-2486 (2002).
    • (2002) Blood , vol.100 , pp. 2479-2486
    • Johnson-Leger, C.A.1    Aurrand-Lions, M.2    Beltraminelli, N.3    Fasel, N.4    Imhof, B.A.5
  • 18
    • 0036718520 scopus 로고    scopus 로고
    • Santoso, S. et al. The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1. J. Exp. Med. 196, 679-691 (2002). In this paper the leukocyte integrin MAC1 is reported to act as a receptor for JAM-C, which supports a crucial role for JAMs in platelet-mediated leukocyte recruitment.
    • Santoso, S. et al. The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1. J. Exp. Med. 196, 679-691 (2002). In this paper the leukocyte integrin MAC1 is reported to act as a receptor for JAM-C, which supports a crucial role for JAMs in platelet-mediated leukocyte recruitment.
  • 19
    • 18644384462 scopus 로고    scopus 로고
    • Junctional adhesion molecule-C regulates the early influx of leukocytes into tissues during inflammation
    • Aurrand-Lions, M. et al. Junctional adhesion molecule-C regulates the early influx of leukocytes into tissues during inflammation. J. Immunol. 174, 6406-6415 (2005).
    • (2005) J. Immunol , vol.174 , pp. 6406-6415
    • Aurrand-Lions, M.1
  • 20
    • 0039027605 scopus 로고    scopus 로고
    • Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludin
    • Bazzoni, G. et al. Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludin. J. Biol. Chem. 275, 20520-20526 (2000).
    • (2000) J. Biol. Chem , vol.275 , pp. 20520-20526
    • Bazzoni, G.1
  • 21
    • 0034623082 scopus 로고    scopus 로고
    • Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1
    • Ebnet, K., Schulz, C. U., Meyer Zu Brickwedde, M. K., Pendl, G. G. & Vestweber, D. Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1. J. Biol. Chem. 275, 27979-27988 (2000).
    • (2000) J. Biol. Chem , vol.275 , pp. 27979-27988
    • Ebnet, K.1    Schulz, C.U.2    Meyer Zu Brickwedde, M.K.3    Pendl, G.G.4    Vestweber, D.5
  • 22
    • 0035898658 scopus 로고    scopus 로고
    • The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)
    • Ebnet, K. et al. The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM). EMBO J. 20, 3738-3748 (2001).
    • (2001) EMBO J , vol.20 , pp. 3738-3748
    • Ebnet, K.1
  • 23
    • 3342982322 scopus 로고    scopus 로고
    • JAM-C is a component of desmosomes and a ligand for CD11b/CD18-mediated neutrophil transepithelial migration
    • Zen, K. et al. JAM-C is a component of desmosomes and a ligand for CD11b/CD18-mediated neutrophil transepithelial migration. Mol. Biol. Cell 15, 3926-3937 (2004).
    • (2004) Mol. Biol. Cell , vol.15 , pp. 3926-3937
    • Zen, K.1
  • 24
    • 12444336848 scopus 로고    scopus 로고
    • The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: A possible role for JAMs in endothelial cell polarity
    • Ebnet, K. et al. The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity. J. Cell Sci. 116, 3879-3891 (2003).
    • (2003) J. Cell Sci , vol.116 , pp. 3879-3891
    • Ebnet, K.1
  • 25
    • 33847315194 scopus 로고    scopus 로고
    • Mandicourt, G., Iden, S., Ebnet, K., Aurrand-Lions, M. & Imhof, B. A. JAM-C regulates tight junctions and integrin-mediated cell adhesion and migration. J. Biol. Chem. 282, 1830-1837 (2006).
    • Mandicourt, G., Iden, S., Ebnet, K., Aurrand-Lions, M. & Imhof, B. A. JAM-C regulates tight junctions and integrin-mediated cell adhesion and migration. J. Biol. Chem. 282, 1830-1837 (2006).
  • 26
    • 0033565947 scopus 로고    scopus 로고
    • Cutting edge: Combined treatment of TNF-α and IFN-γ causes redistribution of junctional adhesion molecule in human endothelial cells
    • Ozaki, H. et al. Cutting edge: combined treatment of TNF-α and IFN-γ causes redistribution of junctional adhesion molecule in human endothelial cells. J. Immunol. 163, 553-557 (1999).
    • (1999) J. Immunol , vol.163 , pp. 553-557
    • Ozaki, H.1
  • 27
    • 0036008013 scopus 로고    scopus 로고
    • 2 integrin LFA-1 involved in transendothelial migration of leukocytes. Nature Immunol. 3, 151-158 (2002). This paper identifies JAM-A as a new ligand for the leukocyte integrin LFA1 and provides the first evidence for a functional relevance of heterophilic JAM interactions.
    • 2 integrin LFA-1 involved in transendothelial migration of leukocytes. Nature Immunol. 3, 151-158 (2002). This paper identifies JAM-A as a new ligand for the leukocyte integrin LFA1 and provides the first evidence for a functional relevance of heterophilic JAM interactions.
  • 28
    • 0035184161 scopus 로고    scopus 로고
    • Reduced expression of junctional adhesion molecule and platelet/endothelial cell adhesion molecule-1 (CD31) at human vascular endothelial junctions by cytokines tumor necrosis factor-α plus interferon-γ does not reduce leukocyte transmigration under flow
    • Shaw, S. K. et al. Reduced expression of junctional adhesion molecule and platelet/endothelial cell adhesion molecule-1 (CD31) at human vascular endothelial junctions by cytokines tumor necrosis factor-α plus interferon-γ does not reduce leukocyte transmigration under flow. Am. J. Pathol. 159, 2281-2291 (2001).
    • (2001) Am. J. Pathol , vol.159 , pp. 2281-2291
    • Shaw, S.K.1
  • 29
    • 0141679018 scopus 로고    scopus 로고
    • 3-integrin complex and its role in angiogenesis.
    • 3-integrin complex and its role in angiogenesis.
  • 30
    • 28744455806 scopus 로고    scopus 로고
    • The role of junctional adhesion molecule-C (JAM-C) in oxidized LDL-mediated leukocyte recruitment
    • Keiper, T. et al. The role of junctional adhesion molecule-C (JAM-C) in oxidized LDL-mediated leukocyte recruitment. FASEB J. 19, 2078-2080 (2005).
    • (2005) FASEB J , vol.19 , pp. 2078-2080
    • Keiper, T.1
  • 31
    • 16244388649 scopus 로고    scopus 로고
    • Involvement of JAM-A in mononuclear cell recruitment on inflamed or atherosclerotic endothelium: Inhibition by soluble JAM-A
    • Ostermann, G. et al. Involvement of JAM-A in mononuclear cell recruitment on inflamed or atherosclerotic endothelium: inhibition by soluble JAM-A. Arterioscler. Thromb. Vasc. Biol. 25, 729-735 (2005).
    • (2005) Arterioscler. Thromb. Vasc. Biol , vol.25 , pp. 729-735
    • Ostermann, G.1
  • 32
    • 33644639731 scopus 로고    scopus 로고
    • Identification of differential protein expression associated with development of unstable human carotid plaques
    • Slevin, M. et al. Identification of differential protein expression associated with development of unstable human carotid plaques. Am. J. Pathol. 168, 1004-1021 (2006).
    • (2006) Am. J. Pathol , vol.168 , pp. 1004-1021
    • Slevin, M.1
  • 33
    • 33947533973 scopus 로고    scopus 로고
    • The F11 receptor (F11R/JAM-A) in atherothrombosis: Overexpression of F11R in atherosclerotic plaques
    • Babinska, A. et al. The F11 receptor (F11R/JAM-A) in atherothrombosis: overexpression of F11R in atherosclerotic plaques. Thromb. Haemost. 97, 272-281 (2007).
    • (2007) Thromb. Haemost , vol.97 , pp. 272-281
    • Babinska, A.1
  • 34
    • 22144433384 scopus 로고    scopus 로고
    • Khandoga, A. et al. Junctional adhesion molecule-A deficiency increases hepatic ischemia-reperfusion injury despite reduction of neutrophil transendothelial migration. Blood 106, 725-733 (2005). This paper implicates endothelial-cell JAM-A in the extravasation of neutrophils in vivo using genetically deficient mice in a model of ischaemia-reperfusion injury of the liver.
    • Khandoga, A. et al. Junctional adhesion molecule-A deficiency increases hepatic ischemia-reperfusion injury despite reduction of neutrophil transendothelial migration. Blood 106, 725-733 (2005). This paper implicates endothelial-cell JAM-A in the extravasation of neutrophils in vivo using genetically deficient mice in a model of ischaemia-reperfusion injury of the liver.
  • 35
    • 0035895050 scopus 로고    scopus 로고
    • Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family members
    • Aurrand-Lions, M., Johnson-Leger, C., Wong, C., Du Pasquier, L. & Imhof, B. A. Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family members. Blood 98, 3699-3707 (2001).
    • (2001) Blood , vol.98 , pp. 3699-3707
    • Aurrand-Lions, M.1    Johnson-Leger, C.2    Wong, C.3    Du Pasquier, L.4    Imhof, B.A.5
  • 36
    • 0035114187 scopus 로고    scopus 로고
    • Characterization and chromosomal localization of JAM-1, a platelet receptor for a stimulatory monoclonal antibody
    • Naik, U. P., Naik, M. U., Eckfeld, K., Martin-DeLeon, P. & Spychala, J. Characterization and chromosomal localization of JAM-1, a platelet receptor for a stimulatory monoclonal antibody. J. Cell Sci. 114, 539-547 (2001).
    • (2001) J. Cell Sci , vol.114 , pp. 539-547
    • Naik, U.P.1    Naik, M.U.2    Eckfeld, K.3    Martin-DeLeon, P.4    Spychala, J.5
  • 37
    • 0034613379 scopus 로고    scopus 로고
    • Homophilic interaction of junctional adhesion molecule
    • Bazzoni, G. et al. Homophilic interaction of junctional adhesion molecule. J. Biol. Chem. 275, 30970-30976 (2000).
    • (2000) J. Biol. Chem , vol.275 , pp. 30970-30976
    • Bazzoni, G.1
  • 38
    • 0036851155 scopus 로고    scopus 로고
    • F11-receptor (F11R/JAM) mediates platelet adhesion to endothelial cells: Role in inflammatory thrombosis
    • Babinska, A. et al. F11-receptor (F11R/JAM) mediates platelet adhesion to endothelial cells: role in inflammatory thrombosis. Thromb. Haemost. 88, 843-850 (2002).
    • (2002) Thromb. Haemost , vol.88 , pp. 843-850
    • Babinska, A.1
  • 39
    • 27744551068 scopus 로고    scopus 로고
    • The homophilic binding of junctional adhesion molecule-C mediates tumor cell-endothelial cell interactions
    • Santoso, S. et al. The homophilic binding of junctional adhesion molecule-C mediates tumor cell-endothelial cell interactions. J. Biol. Chem. 280, 36326-36333 (2005).
    • (2005) J. Biol. Chem , vol.280 , pp. 36326-36333
    • Santoso, S.1
  • 40
    • 26244435565 scopus 로고    scopus 로고
    • 2 integrin: function in junctional complexes and leukocyte adhesion. Mol. Biol. Cell 16, 4992-5003 (2005). This paper provides an interesting analysis of the heterophilic interactions of endothelial-cell JAM-B and JAM-C and its modulation of JAM-C interactions with MAC1.
    • 2 integrin: function in junctional complexes and leukocyte adhesion. Mol. Biol. Cell 16, 4992-5003 (2005). This paper provides an interesting analysis of the heterophilic interactions of endothelial-cell JAM-B and JAM-C and its modulation of JAM-C interactions with MAC1.
  • 41
    • 33645553318 scopus 로고    scopus 로고
    • Endothelial tight junctions: Permeable barriers of the vessel wall
    • Bazzoni, G. Endothelial tight junctions: permeable barriers of the vessel wall. Thromb. Haemost. 95, 36-42 (2006).
    • (2006) Thromb. Haemost , vol.95 , pp. 36-42
    • Bazzoni, G.1
  • 43
    • 1942501686 scopus 로고    scopus 로고
    • Involvement of the junctional adhesion molecule-1 (JAM1) homodimer interface in regulation of epithelial barrier function
    • Mandell, K. J., McCall, I. C. & Parkos, C. A. Involvement of the junctional adhesion molecule-1 (JAM1) homodimer interface in regulation of epithelial barrier function. J. Biol. Chem. 279, 16254-16262 (2004).
    • (2004) J. Biol. Chem , vol.279 , pp. 16254-16262
    • Mandell, K.J.1    McCall, I.C.2    Parkos, C.A.3
  • 44
    • 33751546663 scopus 로고    scopus 로고
    • Junctional adhesion molecule-C regulates vascular endothelial permeability by modulating VE-cadherin-mediated cell-cell contacts
    • Orlova, V. V., Economopoulou, M., Lupu, F., Santoso, S. & Chavakis, T. Junctional adhesion molecule-C regulates vascular endothelial permeability by modulating VE-cadherin-mediated cell-cell contacts. J. Exp. Med. 203, 2703-2714 (2006).
    • (2006) J. Exp. Med , vol.203 , pp. 2703-2714
    • Orlova, V.V.1    Economopoulou, M.2    Lupu, F.3    Santoso, S.4    Chavakis, T.5
  • 45
    • 0344562928 scopus 로고    scopus 로고
    • Leukocyte recruitment in the cerebrospinal fluid of mice with experimental meningitis is inhibited by an antibody to junctional adhesion molecule (JAM)
    • Del Maschio, A. et al. Leukocyte recruitment in the cerebrospinal fluid of mice with experimental meningitis is inhibited by an antibody to junctional adhesion molecule (JAM). J. Exp. Med. 190, 1351-1356 (1999).
    • (1999) J. Exp. Med , vol.190 , pp. 1351-1356
    • Del Maschio, A.1
  • 46
    • 0033823684 scopus 로고    scopus 로고
    • Antibodies to the junctional adhesion molecule cause disruption of endothelial cells and do not prevent leukocyte influx into the meninges after viral or bacterial infection
    • Lechner, F. et al. Antibodies to the junctional adhesion molecule cause disruption of endothelial cells and do not prevent leukocyte influx into the meninges after viral or bacterial infection. J. Infect. Dis. 182, 978-982 (2000).
    • (2000) J. Infect. Dis , vol.182 , pp. 978-982
    • Lechner, F.1
  • 47
    • 33644854759 scopus 로고    scopus 로고
    • Zernecke, A. et al. Importance of junctional adhesion molecule-A for neointimal lesion formation and infiltration in atherosclerosis-prone mice. Arterioscler. Thromb. Vasc. Biol. 26, e10-e13 (2006). This paper reports the first evidence for an important role for JAM-A in neointimal lesion formation and monocyte infiltration after arterial denudation injury.
    • Zernecke, A. et al. Importance of junctional adhesion molecule-A for neointimal lesion formation and infiltration in atherosclerosis-prone mice. Arterioscler. Thromb. Vasc. Biol. 26, e10-e13 (2006). This paper reports the first evidence for an important role for JAM-A in neointimal lesion formation and monocyte infiltration after arterial denudation injury.
  • 48
    • 11144304343 scopus 로고    scopus 로고
    • The junctional adhesion molecule-C promotes neutrophil transendothelial migration in vitro and in vivo
    • Chavakis, T. et al. The junctional adhesion molecule-C promotes neutrophil transendothelial migration in vitro and in vivo. J. Biol. Chem. 279, 55602-55608 (2004).
    • (2004) J. Biol. Chem , vol.279 , pp. 55602-55608
    • Chavakis, T.1
  • 49
    • 8444229240 scopus 로고    scopus 로고
    • 2 integrin lymphocyte function-associated antigen-1 with junctional adhesion molecule-A is mediated by the I domain
    • 2 integrin lymphocyte function-associated antigen-1 with junctional adhesion molecule-A is mediated by the I domain. J. Immunol. 173, 6259-6264 (2004).
    • (2004) J. Immunol , vol.173 , pp. 6259-6264
    • Fraemohs, L.1    Koenen, R.R.2    Ostermann, G.3    Heinemann, B.4    Weber, C.5
  • 51
    • 0034254923 scopus 로고    scopus 로고
    • The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin
    • Boettner, B., Govek, E. E., Cross, J. & Van Aelst, L. The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin. Proc. Natl Acad. Sci. USA 97, 9064-9069 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 9064-9069
    • Boettner, B.1    Govek, E.E.2    Cross, J.3    Van Aelst, L.4
  • 53
    • 19944428045 scopus 로고    scopus 로고
    • Coordinated redistribution of leukocyte LFA-1 and endothelial cell ICAM-1 accompany neutrophil transmigration
    • Shaw, S. K. et al. Coordinated redistribution of leukocyte LFA-1 and endothelial cell ICAM-1 accompany neutrophil transmigration. J. Exp. Med. 200, 1571-1580 (2004).
    • (2004) J. Exp. Med , vol.200 , pp. 1571-1580
    • Shaw, S.K.1
  • 55
    • 14744273494 scopus 로고    scopus 로고
    • The three-dimensional structure of integrins and their ligands, and conformational regulation of cell adhesion
    • Springer, T. A. & Wang, J. H. The three-dimensional structure of integrins and their ligands, and conformational regulation of cell adhesion. Adv. Protein Chem. 68, 29-63 (2004).
    • (2004) Adv. Protein Chem , vol.68 , pp. 29-63
    • Springer, T.A.1    Wang, J.H.2
  • 56
    • 22244438250 scopus 로고    scopus 로고
    • A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes
    • Smith, A. et al. A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes. J. Cell Biol. 170, 141-151 (2005).
    • (2005) J. Cell Biol , vol.170 , pp. 141-151
    • Smith, A.1
  • 57
  • 58
    • 23044465208 scopus 로고    scopus 로고
    • Corada, M. et al. Junctional adhesion molecule-A-deficient polymorphonuclear cells show reduced diapedesis in peritonitis and heart ischemia-reperfusion injury. Proc. Natl Acad. Sci. USA 102, 10634-10639 (2005). This paper describes an interesting role of leukocyte JAM-A in neutrophil polarization and directed migration during inflammatory extravasation.
    • Corada, M. et al. Junctional adhesion molecule-A-deficient polymorphonuclear cells show reduced diapedesis in peritonitis and heart ischemia-reperfusion injury. Proc. Natl Acad. Sci. USA 102, 10634-10639 (2005). This paper describes an interesting role of leukocyte JAM-A in neutrophil polarization and directed migration during inflammatory extravasation.
  • 59
    • 0037251148 scopus 로고    scopus 로고
    • Leukocyte trans-endothelial migration: JAMs add new pieces to the puzzle
    • Chavakis, T., Preissner, K. T. & Santoso, S. Leukocyte trans-endothelial migration: JAMs add new pieces to the puzzle. Thromb. Haemost. 89, 13-17 (2003).
    • (2003) Thromb. Haemost , vol.89 , pp. 13-17
    • Chavakis, T.1    Preissner, K.T.2    Santoso, S.3
  • 60
    • 33846118743 scopus 로고    scopus 로고
    • Platelets as immune cells: Bridging inflammation and cardiovascular disease
    • von Hundelshausen, P. & Weber, C. Platelets as immune cells: bridging inflammation and cardiovascular disease. Circ. Res. 100, 27-40 (2007).
    • (2007) Circ. Res , vol.100 , pp. 27-40
    • von Hundelshausen, P.1    Weber, C.2
  • 61
    • 0025364255 scopus 로고
    • Activation of human platelets by a stimulatory monoclonal antibody
    • Kornecki, E., Walkowiak, B., Naik, U. P. & Ehrlich, Y. H. Activation of human platelets by a stimulatory monoclonal antibody. J. Biol. Chem. 265, 10042-10048 (1990).
    • (1990) J. Biol. Chem , vol.265 , pp. 10042-10048
    • Kornecki, E.1    Walkowiak, B.2    Naik, U.P.3    Ehrlich, Y.H.4
  • 62
    • 21544460952 scopus 로고    scopus 로고
    • Platelet microparticles: A transcellular delivery system for RANTES promoting monocyte recruitment on endothelium
    • Mause, S. F., von Hundelshausen, P., Zernecke, A., Koenen, R. R. & Weber, C. Platelet microparticles: a transcellular delivery system for RANTES promoting monocyte recruitment on endothelium. Arterioscler. Thromb. Vasc. Biol. 25, 1512-1518 (2005).
    • (2005) Arterioscler. Thromb. Vasc. Biol , vol.25 , pp. 1512-1518
    • Mause, S.F.1    von Hundelshausen, P.2    Zernecke, A.3    Koenen, R.R.4    Weber, C.5
  • 63
    • 0030726989 scopus 로고    scopus 로고
    • 3 and stimulated by platelet-activating factor
    • 3 and stimulated by platelet-activating factor. J. Clin. Invest. 100, 2085-2093 (1997).
    • (1997) J. Clin. Invest , vol.100 , pp. 2085-2093
    • Weber, C.1    Springer, T.A.2
  • 64
    • 85047691079 scopus 로고    scopus 로고
    • Increased DC trafficking to lymph nodes and contact hypersensitivity in junctional adhesion molecule-A-deficient mice
    • Cera, M. R. et al. Increased DC trafficking to lymph nodes and contact hypersensitivity in junctional adhesion molecule-A-deficient mice. J. Clin. Invest. 114, 729-738 (2004).
    • (2004) J. Clin. Invest , vol.114 , pp. 729-738
    • Cera, M.R.1
  • 65
    • 33747393306 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 failed to induce angiogenesis in junctional adhesion molecule-deficient mice
    • Cooke, V. G., Naik, M. U. & Naik, U. P. Fibroblast growth factor-2 failed to induce angiogenesis in junctional adhesion molecule-deficient mice. Arterioscler. Thromb. Vasc. Biol. 26, 2005-2011 (2006).
    • (2006) Arterioscler. Thromb. Vasc. Biol , vol.26 , pp. 2005-2011
    • Cooke, V.G.1    Naik, M.U.2    Naik, U.P.3
  • 66
    • 0345991242 scopus 로고    scopus 로고
    • Essential role of junctional adhesion molecule-1 in basic fibroblast growth factor-induced endothelial cell migration
    • Naik, M. U., Vuppalanchi, D. & Naik, U. P. Essential role of junctional adhesion molecule-1 in basic fibroblast growth factor-induced endothelial cell migration. Arterioscler. Thromb. Vasc. Biol. 23, 2165-2171 (2003).
    • (2003) Arterioscler. Thromb. Vasc. Biol , vol.23 , pp. 2165-2171
    • Naik, M.U.1    Vuppalanchi, D.2    Naik, U.P.3
  • 67
    • 21344434097 scopus 로고    scopus 로고
    • Antibody against junctional adhesion molecule-C inhibits angiogenesis and tumor growth
    • Lamagna, C., Hodivala-Dilke, K. M., Imhof, B. A. & Aurrand-Lions, M. Antibody against junctional adhesion molecule-C inhibits angiogenesis and tumor growth. Cancer Res. 65, 5703-5710 (2005).
    • (2005) Cancer Res , vol.65 , pp. 5703-5710
    • Lamagna, C.1    Hodivala-Dilke, K.M.2    Imhof, B.A.3    Aurrand-Lions, M.4
  • 68
    • 34247276545 scopus 로고    scopus 로고
    • Junctional adhesion molecule-C promotes metastatic potential of HT1080 human fibrosarcoma
    • Fuse, C., Ishida, Y., Hikita, T., Asai, T. & Oku, N. Junctional adhesion molecule-C promotes metastatic potential of HT1080 human fibrosarcoma. J. Biol. Chem. 282, 8276-8283 (2007).
    • (2007) J. Biol. Chem , vol.282 , pp. 8276-8283
    • Fuse, C.1    Ishida, Y.2    Hikita, T.3    Asai, T.4    Oku, N.5
  • 69
    • 0033664703 scopus 로고    scopus 로고
    • Adhesion molecules in liver ischemia and reperfusion
    • Martinez-Mier, G., Toledo-Pereyra, L. H. & Ward, P. A. Adhesion molecules in liver ischemia and reperfusion. J. Surg. Res. 94, 185-194 (2000).
    • (2000) J. Surg. Res , vol.94 , pp. 185-194
    • Martinez-Mier, G.1    Toledo-Pereyra, L.H.2    Ward, P.A.3
  • 70
    • 8344256426 scopus 로고    scopus 로고
    • Chemokines: Key regulators of mononuclear cell recruitment in atherosclerotic vascular disease
    • Weber, C., Schober, A. & Zernecke, A. Chemokines: key regulators of mononuclear cell recruitment in atherosclerotic vascular disease. Arterioscler. Thromb. Vasc. Biol. 24, 1997-2008 (2004).
    • (2004) Arterioscler. Thromb. Vasc. Biol , vol.24 , pp. 1997-2008
    • Weber, C.1    Schober, A.2    Zernecke, A.3
  • 71
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson, G. K. Inflammation, atherosclerosis, and coronary artery disease. N. Engl. J. Med. 352, 1685-1695 (2005).
    • (2005) N. Engl. J. Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 72
    • 12144287541 scopus 로고    scopus 로고
    • Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1)
    • Pajukanta, P. et al. Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1). Nature Genet. 36, 371-376 (2004).
    • (2004) Nature Genet , vol.36 , pp. 371-376
    • Pajukanta, P.1
  • 73
    • 24144435303 scopus 로고    scopus 로고
    • Familial combined hyperlipidemia in Mexicans: Association with upstream transcription factor 1 and linkage on chromosome 16q24.1
    • Huertas-Vazquez, A. et al. Familial combined hyperlipidemia in Mexicans: association with upstream transcription factor 1 and linkage on chromosome 16q24.1. Arterioscler. Thromb. Vasc. Biol. 25, 1985-1991 (2005).
    • (2005) Arterioscler. Thromb. Vasc. Biol , vol.25 , pp. 1985-1991
    • Huertas-Vazquez, A.1
  • 74
    • 0037231665 scopus 로고    scopus 로고
    • Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E
    • Huo, Y. et al. Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E. Nature Med. 9, 61-67 (2003).
    • (2003) Nature Med , vol.9 , pp. 61-67
    • Huo, Y.1
  • 75
    • 0035799376 scopus 로고    scopus 로고
    • RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium
    • von Hundelshausen, P. et al. RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium. Circulation 103, 1772-1777 (2001).
    • (2001) Circulation , vol.103 , pp. 1772-1777
    • von Hundelshausen, P.1
  • 76
    • 0037013246 scopus 로고    scopus 로고
    • A transmembrane tight junction protein selectively expressed on endothelial cells and platelets
    • Nasdala, I. et al. A transmembrane tight junction protein selectively expressed on endothelial cells and platelets. J. Biol. Chem. 277, 16294-16303 (2002).
    • (2002) J. Biol. Chem , vol.277 , pp. 16294-16303
    • Nasdala, I.1
  • 77
    • 33745813930 scopus 로고    scopus 로고
    • ESAM supports neutrophil extravasation, activation of Rho, and VEGF-induced vascular permeability
    • Wegmann, F. et al. ESAM supports neutrophil extravasation, activation of Rho, and VEGF-induced vascular permeability. J. Exp. Med. 203, 1671-1677 (2006).
    • (2006) J. Exp. Med , vol.203 , pp. 1671-1677
    • Wegmann, F.1
  • 78
    • 0035910098 scopus 로고    scopus 로고
    • The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction
    • Cohen, C. J. et al. The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction. Proc. Natl Acad. Sci. USA 98, 15191-15196 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 15191-15196
    • Cohen, C.J.1
  • 79
    • 3242656311 scopus 로고    scopus 로고
    • Cytokine-mediated downregulation of coxsackievirus-adenovirus receptor in endothelial cells
    • Vincent, T., Pettersson, R. F., Crystal, R. G. & Leopold, P. L. Cytokine-mediated downregulation of coxsackievirus-adenovirus receptor in endothelial cells. J. Virol. 78, 8047-8058 (2004).
    • (2004) J. Virol , vol.78 , pp. 8047-8058
    • Vincent, T.1    Pettersson, R.F.2    Crystal, R.G.3    Leopold, P.L.4
  • 80
    • 9144243706 scopus 로고    scopus 로고
    • The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP1) within the tight junction
    • Coyne, C. B., Voelker, T., Pichla, S. L. & Bergelson, J. M. The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP1) within the tight junction. J. Biol. Chem. 279, 48079-48084 (2004).
    • (2004) J. Biol. Chem , vol.279 , pp. 48079-48084
    • Coyne, C.B.1    Voelker, T.2    Pichla, S.L.3    Bergelson, J.M.4
  • 81
    • 33644895026 scopus 로고    scopus 로고
    • Coxsackievirus and adenovirus receptor (CAR) is expressed in male germ cells and forms a complex with the differentiation factor JAM-C in mouse testis
    • Mirza, M. et al. Coxsackievirus and adenovirus receptor (CAR) is expressed in male germ cells and forms a complex with the differentiation factor JAM-C in mouse testis. Exp. Cell Res. 312, 817-830 (2006).
    • (2006) Exp. Cell Res , vol.312 , pp. 817-830
    • Mirza, M.1


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