Reversibility of defective hematopoiesis caused by telomere shortening in telomerase knockout mice

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Raval, Aparna ^a   Behbehani, Gregory K ^a,b   Nguyen, Le Xuan Truong ^a   Thomas, Daniel ^a,b   Kusler, Brenda ^a   Garbuzov, Alina ^c   Ramunas, John ^b   Holbrook, Colin ^b   Park, Christopher Y ^d   Blau, Helen ^b   Nolan, Garry P ^b   Artandi, Steven E ^c   Mitchell, Beverly S ^a  

^a STANFORD CANCER INSTITUTE   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c STANFORD UNIVERSITY   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; CASPASE 3; CD150 ANTIGEN; CD16 ANTIGEN; CD34 ANTIGEN; HISTONE H2AX; KI 67 ANTIGEN; PROTEIN P53; RETINOBLASTOMA PROTEIN; TELOMERASE;

ANEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL COUNT; CELL CYCLE ARREST; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL RENEWAL; CONTROLLED STUDY; DNA DAMAGE CHECKPOINT; ENZYME ACTIVITY; ENZYME REACTIVATION; ERYTHROID PRECURSOR CELL; ERYTHROPOIESIS; HEMATOPOIESIS; INTRACELLULAR SIGNALING; MOUSE; MYELOID PROGENITOR CELL; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; TELOMERE SHORTENING; ANIMAL; APLASTIC ANEMIA; DNA DAMAGE; GENETICS; KNOCKOUT MOUSE; METABOLISM; TELOMERE;

MURINAE; MUS;

ANEMIA, APLASTIC; ANIMALS; CELL PROLIFERATION; DNA DAMAGE; ERYTHROID PRECURSOR CELLS; HEMATOPOIESIS; MICE; MICE, KNOCKOUT; TELOMERASE; TELOMERE; TELOMERE SHORTENING;

EID: 84940055256     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0131722     Document Type: Article

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