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Volumn 10, Issue 7, 2015, Pages

Nano-drugs based on nano sterically stabilized liposomes for the treatment of inflammatory neurodegenerative diseases

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; HYDROCORTISONE SODIUM SUCCINATE; LIPOSOME; METHYLPREDNISOLONE SODIUM SUCCINATE; NANOCARRIER; NANOSTERICALLY STABILIZED LIPOSOME; NITROXIDE; PEPTIDE; TEMPAMINE; UNCLASSIFIED DRUG; AMINE OXIDE; ANTIINFLAMMATORY AGENT; NANOPARTICLE; PRODRUG;

EID: 84940042314     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0130442     Document Type: Article
Times cited : (56)

References (80)
  • 1
    • 77956302879 scopus 로고    scopus 로고
    • Inflammation in neurological disorders: A help or a hindrance?
    • PMID: 20817918
    • Yong VW. Inflammation in neurological disorders: A help or a hindrance? The Neuroscientist. 2010; 16 (4):408-20. doi:10.1177/1073858410371379 PMID: 20817918.
    • (2010) The Neuroscientist , vol.16 , Issue.4 , pp. 408-420
    • Yong, V.W.1
  • 2
    • 46749099351 scopus 로고    scopus 로고
    • New therapeutic targets in the neurovascular pathway in Alzheimer's disease
    • PMID: 18625452
    • Zlokovic BV. New therapeutic targets in the neurovascular pathway in Alzheimer's disease. Neurotherapeutics. 2008; 5(3):409-14. doi:10.1016/j.nurt.2008.05.011 PMID: 18625452.
    • (2008) Neurotherapeutics , vol.5 , Issue.3 , pp. 409-414
    • Zlokovic, B.V.1
  • 3
    • 33845434297 scopus 로고    scopus 로고
    • Glucocorticoids in multiple sclerosis and experimental autoimmune encephalomyelitis
    • PMID: 17144780
    • Reichardt HM, Gold R, Lühder F. Glucocorticoids in multiple sclerosis and experimental autoimmune encephalomyelitis. Expert review of neurotherapeutics. 2006; 6(11):1657-70. PMID: 17144780.
    • (2006) Expert Review of Neurotherapeutics , vol.6 , Issue.11 , pp. 1657-1670
    • Reichardt, H.M.1    Gold, R.2    Lühder, F.3
  • 5
    • 0037029424 scopus 로고    scopus 로고
    • Multiple sclerosis
    • PMID: 11955556
    • Compston A, Coles A. Multiple sclerosis. Lancet. 2002; 359(9313):1221-31. PMID: 11955556.
    • (2002) Lancet , vol.359 , Issue.9313 , pp. 1221-1231
    • Compston, A.1    Coles, A.2
  • 6
    • 1542316096 scopus 로고    scopus 로고
    • Blood-brain barrier permeability and monocyte infiltration in experimental allergic encephalomyelitis a quantitative MRI study
    • Floris S, Blezer E, Schreibelt G, Döpp E, van der Pol S, Schadee-Eestermans I, et al. Blood-brain barrier permeability and monocyte infiltration in experimental allergic encephalomyelitis A quantitative MRI study. Brain. 2004; 127(3):616-27.
    • (2004) Brain , vol.127 , Issue.3 , pp. 616-627
    • Floris, S.1    Blezer, E.2    Schreibelt, G.3    Döpp, E.4    Van Der Pol, S.5    Schadee-Eestermans, I.6
  • 7
    • 33746729791 scopus 로고    scopus 로고
    • Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
    • Gold R, Linington C, Lassmann H. Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research. Brain. 2006; 129(8):1953-71.
    • (2006) Brain , vol.129 , Issue.8 , pp. 1953-1971
    • Gold, R.1    Linington, C.2    Lassmann, H.3
  • 8
    • 0033870097 scopus 로고    scopus 로고
    • Multiple sclerosis and chronic autoimmune encephalomyelitis: A comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions
    • PMID: 10880396
    • Kornek B, Storch MK, Weissert R, Wallstroem E, Stefferl A, Olsson T, et al. Multiple sclerosis and chronic autoimmune encephalomyelitis: A comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions. Am J Pathol. 2000; 157(1):267-76. PMID: 10880396.
    • (2000) Am J Pathol , vol.157 , Issue.1 , pp. 267-276
    • Kornek, B.1    Storch, M.K.2    Weissert, R.3    Wallstroem, E.4    Stefferl, A.5    Olsson, T.6
  • 9
    • 80053577093 scopus 로고    scopus 로고
    • Fabrication principles and their contribution to the superior in vivo therapeutic efficacy of nano-liposomes remote loaded with glucocorticoids
    • PMID: 21998684
    • Avnir Y, Turjeman K, Tulchinsky D, Sigal A, Kizelsztein P, Tzemach D, et al. Fabrication Principles and Their Contribution to the Superior in Vivo Therapeutic Efficacy of Nano-Liposomes Remote Loaded with Glucocorticoids. PloS one. 2011; 6(10):e25721. doi:10.1371/journal.pone.0025721 PMID: 21998684.
    • (2011) PloS One , vol.6 , Issue.10 , pp. e25721
    • Avnir, Y.1    Turjeman, K.2    Tulchinsky, D.3    Sigal, A.4    Kizelsztein, P.5    Tzemach, D.6
  • 10
    • 38149100039 scopus 로고    scopus 로고
    • Amphipathic weak acid glucocorticoid prodrugs remote-loaded into sterically stabilized nanoliposomes evaluated in arthritic rats and in a beagle dog: A novel approach to treating autoimmune arthritis
    • Avnir Y, Ulmansky R, Wasserman V, Even-Chen S, Broyer M, Barenholz Y, et al. Amphipathic weak acid glucocorticoid prodrugs remote-loaded into sterically stabilized nanoliposomes evaluated in arthritic rats and in a Beagle dog: A novel approach to treating autoimmune arthritis. Arthritis & Rheumatism. 2008; 58(1):119-29.
    • (2008) Arthritis & Rheumatism , vol.58 , Issue.1 , pp. 119-129
    • Avnir, Y.1    Ulmansky, R.2    Wasserman, V.3    Even-Chen, S.4    Broyer, M.5    Barenholz, Y.6
  • 11
    • 68049102034 scopus 로고    scopus 로고
    • Pegylated nanoliposomes remoteloaded with the antioxidant tempamine ameliorate experimental autoimmune encephalomyelitis
    • PMID: 19564052
    • Kizelsztein P, Ovadia H, Garbuzenko O, Sigal A, Barenholz Y. Pegylated nanoliposomes remoteloaded with the antioxidant tempamine ameliorate experimental autoimmune encephalomyelitis. Journal of neuroimmunology. 2009; 213(1-2):20-5. doi:10.1016/j.jneuroim.2009.05.019 PMID: 19564052.
    • (2009) Journal of Neuroimmunology , vol.213 , Issue.1-2 , pp. 20-25
    • Kizelsztein, P.1    Ovadia, H.2    Garbuzenko, O.3    Sigal, A.4    Barenholz, Y.5
  • 12
    • 84861660607 scopus 로고    scopus 로고
    • Glucocorticoids in nano-liposomes administered intravenously and subcutaneously to adjuvant arthritis rats are superior to the free drugs in suppressing arthritis and inflammatory cytokines
    • Ulmansky R, Turjeman K, Baru M, Katzavian G, Harel M, Sigal A, et al. Glucocorticoids in nano-liposomes administered intravenously and subcutaneously to adjuvant arthritis rats are superior to the free drugs in suppressing arthritis and inflammatory cytokines. Journal of Controlled Release. 2011.
    • (2011) Journal of Controlled Release
    • Ulmansky, R.1    Turjeman, K.2    Baru, M.3    Katzavian, G.4    Harel, M.5    Sigal, A.6
  • 13
    • 33947123224 scopus 로고    scopus 로고
    • The antioxidant tempamine: In vitro antitumor and neuroprotective effects and optimization of liposomal encapsulation and release
    • PMID: 17279678
    • Wasserman V, Kizelsztein P, Garbuzenko O, Kohen R, Ovadia H, Tabakman R, et al. The antioxidant tempamine: In vitro antitumor and neuroprotective effects and optimization of liposomal encapsulation and release. Langmuir. 2007; 23(4):1937-47. PMID: 17279678.
    • (2007) Langmuir , vol.23 , Issue.4 , pp. 1937-1947
    • Wasserman, V.1    Kizelsztein, P.2    Garbuzenko, O.3    Kohen, R.4    Ovadia, H.5    Tabakman, R.6
  • 14
    • 0033946875 scopus 로고    scopus 로고
    • Steriods for multiple sclerosis and optic neuritis: A meta-analysis of randomized controlled clinical trials
    • PMID: 10929272
    • Brusaferri F, Candelise L. Steriods for multiple sclerosis and optic neuritis: A meta-analysis of randomized controlled clinical trials. Journal of neurology. 2000; 247(6):435-42. PMID: 10929272.
    • (2000) Journal of Neurology , vol.247 , Issue.6 , pp. 435-442
    • Brusaferri, F.1    Candelise, L.2
  • 15
    • 0023194967 scopus 로고
    • A double-blind controlled trial of high dose methylprednisolone in patients with multiple sclerosis: 1. Clinical effects
    • Milligan N, Newcombe R, Compston D. A double-blind controlled trial of high dose methylprednisolone in patients with multiple sclerosis: 1. Clinical effects. Journal of Neurology, Neurosurgery & Psychiatry. 1987; 50(5):511-6.
    • (1987) Journal of Neurology, Neurosurgery & Psychiatry , vol.50 , Issue.5 , pp. 511-516
    • Milligan, N.1    Newcombe, R.2    Compston, D.3
  • 18
    • 79961083445 scopus 로고    scopus 로고
    • Optimizing the therapeutic index of liposomal glucocorticoids in experimental arthritis
    • PMID: 21440612
    • Hoven J, Hofkens W, Wauben M, Wagenaar-Hilbers J, Beijnen J, Nuijen B, et al. Optimizing the therapeutic index of liposomal glucocorticoids in experimental arthritis. International Journal of Pharmaceutics. 2011; 416(2):471-7. doi:10.1016/j.ijpharm.2011.03.025 PMID: 21440612.
    • (2011) International Journal of Pharmaceutics , vol.416 , Issue.2 , pp. 471-477
    • Hoven, J.1    Hofkens, W.2    Wauben, M.3    Wagenaar-Hilbers, J.4    Beijnen, J.5    Nuijen, B.6
  • 19
    • 43449095693 scopus 로고    scopus 로고
    • Liposomal glucocorticosteroids in treatment of chronic autoimmune demyelination: Long-term protective effects and enhanced efficacy of methylprednisolone formulations
    • PMID: 18394606
    • Linker RA, Weller C, Lühder F, Mohr A, Schmidt J, Knauth M, et al. Liposomal glucocorticosteroids in treatment of chronic autoimmune demyelination: long-term protective effects and enhanced efficacy of methylprednisolone formulations. Experimental neurology. 2008; 211(2):397-406. doi:10.1016/j.expneurol.2008.02.005 PMID: 18394606.
    • (2008) Experimental Neurology , vol.211 , Issue.2 , pp. 397-406
    • Linker, R.A.1    Weller, C.2    Lühder, F.3    Mohr, A.4    Schmidt, J.5    Knauth, M.6
  • 20
    • 0043268760 scopus 로고    scopus 로고
    • Drug targeting by long-circulating liposomal glucocorticosteroids increases therapeutic efficacy in a model of multiple sclerosis
    • Schmidt J, Metselaar JM, Wauben MH, Toyka KV, Storm G, Gold R. Drug targeting by long-circulating liposomal glucocorticosteroids increases therapeutic efficacy in a model of multiple sclerosis. Brain. 2003; 126(8):1895-904.
    • (2003) Brain , vol.126 , Issue.8 , pp. 1895-1904
    • Schmidt, J.1    Metselaar, J.M.2    Wauben, M.H.3    Toyka, K.V.4    Storm, G.5    Gold, R.6
  • 21
    • 0034796353 scopus 로고    scopus 로고
    • Role of free radicals in the neurodegenerative diseases: Therapeutic implications for antioxidant treatment
    • Halliwell B. Role of free radicals in the neurodegenerative diseases: Therapeutic implications for antioxidant treatment. Drugs & aging. 2001; 18(9):685-716.
    • (2001) Drugs & Aging , vol.18 , Issue.9 , pp. 685-716
    • Halliwell, B.1
  • 22
    • 0038448961 scopus 로고    scopus 로고
    • Upregulation of expression from the FRDA genomic locus for the therapy of friedreich ataxia
    • PMID: 12516053
    • Sarsero JP, Li L, Wardan H, Sitte K, Williamson R, Ioannou PA. Upregulation of expression from the FRDA genomic locus for the therapy of Friedreich ataxia. The journal of gene medicine. 2003; 5(1):72- 81. PMID: 12516053.
    • (2003) The Journal of Gene Medicine , vol.5 , Issue.1 , pp. 72-81
    • Sarsero, J.P.1    Li, L.2    Wardan, H.3    Sitte, K.4    Williamson, R.5    Ioannou, P.A.6
  • 23
    • 0032902974 scopus 로고    scopus 로고
    • Oxidative alterations in Alzheimer's disease
    • PMID: 9989456
    • Markesbery WR, Carney JM. Oxidative alterations in Alzheimer's disease. Brain Pathology. 1999; 9 (1):133-46. PMID: 9989456.
    • (1999) Brain Pathology , vol.9 , Issue.1 , pp. 133-146
    • Markesbery, W.R.1    Carney, J.M.2
  • 24
    • 0034662806 scopus 로고    scopus 로고
    • Oxidative damage to mitochondrial DNA and activity of mitochondrial enzymes in chronic active lesions of multiple sclerosis
    • PMID: 10980305
    • Lu F, Selak M, O'Connor J, Croul S, Lorenzana C, Butunoi C, et al. Oxidative damage to mitochondrial DNA and activity of mitochondrial enzymes in chronic active lesions of multiple sclerosis. Journal of the neurological sciences. 2000; 177(2):95-103. PMID: 10980305.
    • (2000) Journal of the Neurological Sciences , vol.177 , Issue.2 , pp. 95-103
    • Lu, F.1    Selak, M.2    O'Connor, J.3    Croul, S.4    Lorenzana, C.5    Butunoi, C.6
  • 26
    • 0030001780 scopus 로고    scopus 로고
    • Oxidative stress and antioxidant therapy in Parkinson's disease
    • PMID: 8830346
    • Ebadi M SS, Baxi MD. Oxidative stress and antioxidant therapy in Parkinson's disease. Prog Neurobiol. 1996; 48:1-19. PMID: 8830346.
    • (1996) Prog Neurobiol , vol.48 , pp. 1-19
    • Ebadi, M.S.S.1    Baxi, M.D.2
  • 28
    • 0021722357 scopus 로고
    • Nitroxyl spin label contrast enhancers for magnetic resonance imaging. Studies of acute toxicity and mutagenesis
    • PMID: 6511262
    • Afzal V, Brasch RC, Nitecki DE, Wolff S. Nitroxyl spin label contrast enhancers for magnetic resonance imaging. Studies of acute toxicity and mutagenesis. Investigative radiology. 1984; 19(6):549. PMID: 6511262.
    • (1984) Investigative Radiology , vol.19 , Issue.6 , pp. 549
    • Afzal, V.1    Brasch, R.C.2    Nitecki, D.E.3    Wolff, S.4
  • 29
    • 0026671446 scopus 로고
    • Nitroxide-mediated protection against X-ray-and neocarzinostatin-induced DNA damage
    • PMID: 1459474
    • DeGraff WG, Krishna MC, Kaufman D, Mitchell JB. Nitroxide-mediated protection against X-ray-and neocarzinostatin-induced DNA damage. Free Radical Biology and Medicine. 1992; 13(5):479-87. PMID: 1459474.
    • (1992) Free Radical Biology and Medicine , vol.13 , Issue.5 , pp. 479-487
    • De Graff, W.G.1    Krishna, M.C.2    Kaufman, D.3    Mitchell, J.B.4
  • 32
    • 0030808443 scopus 로고    scopus 로고
    • Tempol inhibits neutrophil and hydrogen peroxide-mediated DNA damage
    • PMID: 9378367
    • Hahn SM, Mitchell JB, Shacter E. Tempol inhibits neutrophil and hydrogen peroxide-mediated DNA damage. Free Radical Biology and Medicine. 1997; 23(6):879-84. PMID: 9378367.
    • (1997) Free Radical Biology and Medicine , vol.23 , Issue.6 , pp. 879-884
    • Hahn, S.M.1    Mitchell, J.B.2    Shacter, E.3
  • 34
    • 0019475132 scopus 로고
    • Initial rate studies of hydrolysis and acyl migration in methylprednisolone 21-hemisuccinate and 17-hemisuccinate
    • Epub 1981/02/01. PMID: 7009782
    • Anderson BD, Taphouse V. Initial rate studies of hydrolysis and acyl migration in methylprednisolone 21-hemisuccinate and 17-hemisuccinate. J Pharm Sci. 1981; 70(2):181-6. Epub 1981/02/01. PMID: 7009782.
    • (1981) J Pharm Sci , vol.70 , Issue.2 , pp. 181-186
    • Anderson, B.D.1    Taphouse, V.2
  • 35
    • 70449246528 scopus 로고
    • Phosphorus assay in column chromatography
    • Epub 1959/03/01. PMID: 13641241
    • Bartlett GR. Phosphorus assay in column chromatography. J Biol Chem. 1959; 234(3):466-8. Epub 1959/03/01. PMID: 13641241.
    • (1959) J Biol Chem. , vol.234 , Issue.3 , pp. 466-468
    • Bartlett, G.R.1
  • 36
    • 82955195917 scopus 로고    scopus 로고
    • Functionalization with apoederived peptides enhances the interaction with brain capillary endothelial cells of nanoliposomes binding amyloid-beta peptide
    • Re F, Cambianica I, Sesana S, Salvati E, Cagnotto A, Salmona M, et al. Functionalization with ApoEderived peptides enhances the interaction with brain capillary endothelial cells of nanoliposomes binding amyloid-beta peptide. Journal of biotechnology. 2011; 156(4):341-6.
    • (2011) Journal of Biotechnology , vol.156 , Issue.4 , pp. 341-346
    • Re, F.1    Cambianica, I.2    Sesana, S.3    Salvati, E.4    Cagnotto, A.5    Salmona, M.6
  • 37
    • 0027221517 scopus 로고
    • Amino acid sequence rerms represents the active domain of amyloid beta/A4 protein precursor that promotes fibroblast growth
    • PMID: 8491779
    • Ninomiya H, Roch J-M, Sundsmo MP, Otero D, Saitoh T. Amino acid sequence RERMS represents the active domain of amyloid beta/A4 protein precursor that promotes fibroblast growth. The Journal of cell biology. 1993; 121(4):879-86. PMID: 8491779.
    • (1993) The Journal of Cell Biology , vol.121 , Issue.4 , pp. 879-886
    • Ninomiya, H.1    Roch, J.-M.2    Sundsmo, M.P.3    Otero, D.4    Saitoh, T.5
  • 38
    • 84861692245 scopus 로고    scopus 로고
    • A new liposome-based gene delivery system targeting lung epithelial cells using endothelin antagonist
    • PMID: 22079949
    • Allon N, Saxena A, Chambers C, Doctor BP. A new liposome-based gene delivery system targeting lung epithelial cells using endothelin antagonist. Journal of Controlled Release. 2012; 160(2):217-24. doi:10.1016/j.jconrel.2011.10.033 PMID: 22079949.
    • (2012) Journal of Controlled Release , vol.160 , Issue.2 , pp. 217-224
    • Allon, N.1    Saxena, A.2    Chambers, C.3    Doctor, B.P.4
  • 40
    • 78649503199 scopus 로고    scopus 로고
    • X+: A comprehensive computationally accelerated structure analysis tool for solution X-ray scattering from supramolecular self-assemblies
    • Ben-Nun T, Ginsburg A, Szekely P, Raviv U. X+: A comprehensive computationally accelerated structure analysis tool for solution X-ray scattering from supramolecular self-assemblies. Journal of Applied Crystallography. 2010; 43(6):1522-31. doi: 10.1107/S0021889810032772.
    • (2010) Journal of Applied Crystallography , vol.43 , Issue.6 , pp. 1522-1531
    • Ben-Nun, T.1    Ginsburg, A.2    Szekely, P.3    Raviv, U.4
  • 41
    • 77955543990 scopus 로고    scopus 로고
    • Solution x-ray scattering form factors of supramolecular self-assembled structures
    • PMID: 20695550
    • Székely P, Ginsburg A, Ben-Nun T, Raviv U. Solution X-ray scattering form factors of supramolecular self-assembled structures. Langmuir. 2010; 26(16):13110-29. doi:10.1021/la101433t PMID: 20695550.
    • (2010) Langmuir , vol.26 , Issue.16 , pp. 13110-13129
    • Székely, P.1    Ginsburg, A.2    Ben-Nun, T.3    Raviv, U.4
  • 42
    • 68949208430 scopus 로고    scopus 로고
    • Liposome drugs' loading efficiency: A working model based on loading conditions and drug's physicochemical properties
    • PMID: 19508880
    • Zucker D, Marcus D, Barenholz Y, Goldblum A. Liposome drugs' loading efficiency: A working model based on loading conditions and drug's physicochemical properties. Journal of Controlled Release. 2009; 139(1):73-80. doi:10.1016/j.jconrel.2009.05.036 PMID: 19508880.
    • (2009) Journal of Controlled Release , vol.139 , Issue.1 , pp. 73-80
    • Zucker, D.1    Marcus, D.2    Barenholz, Y.3    Goldblum, A.4
  • 44
    • 0003095291 scopus 로고    scopus 로고
    • Structure and properties of membranes
    • Baszkin A, Norde W, editors.: Marcel Dekker
    • Barenholz Y, Cevc G. Structure and properties of membranes. In: Baszkin A, Norde W, editors. Physical chemistry of biological surfaces: Marcel Dekker; 2000. p. 171-241.
    • (2000) Physical Chemistry of Biological Surfaces , pp. 171-241
    • Barenholz, Y.1    Cevc, G.2
  • 46
    • 79551681498 scopus 로고    scopus 로고
    • Influence of lipid composition on the thermotropic behavior and size distribution of mixed cationic liposomes
    • PMID: 21256506
    • Barenholz Y, Bombelli C, Bonicelli MG, Profio Pd, Giansanti L, Mancini G, et al. Influence of lipid composition on the thermotropic behavior and size distribution of mixed cationic liposomes. Journal of colloid and interface science. 2011; 356(1):46-53. doi:10.1016/j.jcis.2010.11.062 PMID: 21256506.
    • (2011) Journal of Colloid and Interface Science , vol.356 , Issue.1 , pp. 46-53
    • Barenholz, Y.1    Bombelli, C.2    Bonicelli, M.G.3    Profio, P.4    Giansanti, L.5    Mancini, G.6
  • 47
    • 84873629694 scopus 로고    scopus 로고
    • Effect of capsid confinement on the chromatin organization of the SV40 minichromosome
    • PMID: 23258701
    • Saper G, Kler S, Asor R, Oppenheim A, Raviv U, Harries D. Effect of capsid confinement on the chromatin organization of the SV40 minichromosome. Nucleic acids research. 2013; 41(3):1569-80. doi:10.1093/nar/gks1270 PMID: 23258701.
    • (2013) Nucleic Acids Research , vol.41 , Issue.3 , pp. 1569-1580
    • Saper, G.1    Kler, S.2    Asor, R.3    Oppenheim, A.4    Raviv, U.5    Harries, D.6
  • 49
    • 19744375307 scopus 로고    scopus 로고
    • Effect of grafted PEG on liposome size and on compressibility and packing of lipid bilayer
    • PMID: 15921973
    • Garbuzenko O, Barenholz Y, Priev A. Effect of grafted PEG on liposome size and on compressibility and packing of lipid bilayer. Chemistry and physics of lipids. 2005; 135(2):117-29. PMID: 15921973.
    • (2005) Chemistry and Physics of Lipids , vol.135 , Issue.2 , pp. 117-129
    • Garbuzenko, O.1    Barenholz, Y.2    Priev, A.3
  • 54
    • 0031958273 scopus 로고    scopus 로고
    • A new hypothesis of modular glucocorticoid actions: Steroid treatment of rheumatic diseases revisited
    • Buttgereit F, Wehling M, Burmester GR. A new hypothesis of modular glucocorticoid actions: steroid treatment of rheumatic diseases revisited. Arthritis & Rheumatism. 1998; 41(5):761-7.
    • (1998) Arthritis & Rheumatism , vol.41 , Issue.5 , pp. 761-767
    • Buttgereit, F.1    Wehling, M.2    Burmester, G.R.3
  • 56
    • 0035796894 scopus 로고    scopus 로고
    • Mechanism of action of glucocorticosteroid hormones: Possible implications for therapy of neuroimmunological disorders
    • Gold R, Buttgereit F, Toyka KV. Mechanism of action of glucocorticosteroid hormones: possible implications for therapy of neuroimmunological disorders. Journal of neuroimmunology. 2001; 117(1):1-8.
    • (2001) Journal of Neuroimmunology , vol.117 , Issue.1 , pp. 1-8
    • Gold, R.1    Buttgereit, F.2    Toyka, K.V.3
  • 58
    • 0029951471 scopus 로고    scopus 로고
    • Targeted delivery of doxorubicin via sterically stabilized immunoliposomes: Pharmacokinetics and biodistribution in tumor-bearing mice
    • PMID: 8792423
    • Emanuel N, Kedar E, Bolotin EM, Smorodinsky NI, Barenholz Y. Targeted delivery of doxorubicin via sterically stabilized immunoliposomes: pharmacokinetics and biodistribution in tumor-bearing mice. Pharmaceutical research. 1996; 13(6):861-8. PMID: 8792423.
    • (1996) Pharmaceutical Research , vol.13 , Issue.6 , pp. 861-868
    • Emanuel, N.1    Kedar, E.2    Bolotin, E.M.3    Smorodinsky, N.I.4    Barenholz, Y.5
  • 59
    • 13344294370 scopus 로고    scopus 로고
    • In vivo MRI and its histological correlates in acute adoptive transfer experimental allergic encephalomyelitis quantification of inflammation and oedema
    • Morrissey SP, Stodal H, Zettl U, Simonis C, Jung S, Kiefer R, et al. In vivo MRI and its histological correlates in acute adoptive transfer experimental allergic encephalomyelitis quantification of inflammation and oedema. Brain. 1996; 119(1):239-48.
    • (1996) Brain , vol.119 , Issue.1 , pp. 239-248
    • Morrissey, S.P.1    Stodal, H.2    Zettl, U.3    Simonis, C.4    Jung, S.5    Kiefer, R.6
  • 60
    • 0030274316 scopus 로고    scopus 로고
    • Corticosteroid treatment of experimental autoimmune encephalomyelitis in the lewis rat results in loss of vβ8. 2+ and myelin basic protein-reactive cells from the spinal cord, with increased total t-cell apoptosis but reduced apoptosis of vβ8. 2+ cells
    • PMID: 8898717
    • McCombe P, Nickson I, Tabi Z, Pender M. Corticosteroid treatment of experimental autoimmune encephalomyelitis in the Lewis rat results in loss of Vβ8. 2+ and myelin basic protein-reactive cells from the spinal cord, with increased total T-cell apoptosis but reduced apoptosis of Vβ8. 2+ cells. Journal of neuroimmunology. 1996; 70(2):93-101. PMID: 8898717.
    • (1996) Journal of Neuroimmunology , vol.70 , Issue.2 , pp. 93-101
    • McCombe, P.1    Nickson, I.2    Tabi, Z.3    Pender, M.4
  • 61
    • 0024361063 scopus 로고
    • Relative efficacy of intravenous methylprednisolone and ACTH in the treatment of acute relapse in ms
    • PMID: 2544829
    • Thompson A, Kennard C, Swash M, Summers B, Yuill G, Shepherd D, et al. Relative efficacy of intravenous methylprednisolone and ACTH in the treatment of acute relapse in MS. Neurology. 1989; 39 (7):969-. PMID: 2544829.
    • (1989) Neurology , vol.39 , Issue.7 , pp. 969
    • Thompson, A.1    Kennard, C.2    Swash, M.3    Summers, B.4    Yuill, G.5    Shepherd, D.6
  • 62
    • 0022633684 scopus 로고
    • High-dose intravenous methylprednisolone in the treatment of multiple sclerosis clinical-immunologic correlations
    • PMID: 3511404
    • Durelli L, Cocito D, Riccio A, Barile C, Bergamasco B, Baggio G, et al. High-dose intravenous methylprednisolone in the treatment of multiple sclerosis Clinical-immunologic correlations. Neurology. 1986; 36(2):238-. PMID: 3511404.
    • (1986) Neurology , vol.36 , Issue.2 , pp. 238
    • Durelli, L.1    Cocito, D.2    Riccio, A.3    Barile, C.4    Bergamasco, B.5    Baggio, G.6
  • 64
    • 0000723768 scopus 로고
    • Multiple sclerosis. Treatment of acute exacerbations with corticotrophin (ACTH)
    • PMID: 14474011
    • Miller H, Newell D, Ridley A. Multiple sclerosis. Treatment of acute exacerbations with corticotrophin (ACTH). Lancet. 1961; 2(7212):1120. PMID: 14474011.
    • (1961) Lancet , vol.2 , Issue.7212 , pp. 1120
    • Miller, H.1    Newell, D.2    Ridley, A.3
  • 66
    • 0022633485 scopus 로고
    • The effect of dexamethasone on l-alpha-lysophosphatidyl choline (lysolecithin)- induced demyelination of the rat spinal cord
    • PMID: 3947247
    • Triarhou LC, Herndon RM. The effect of dexamethasone on L-alpha-lysophosphatidyl choline (lysolecithin)- induced demyelination of the rat spinal cord. Archives of neurology. 1986; 43(2):121. PMID: 3947247.
    • (1986) Archives of Neurology , vol.43 , Issue.2 , pp. 121
    • Triarhou, L.C.1    Herndon, R.M.2
  • 67
    • 0024990661 scopus 로고
    • Breakdown of the bloodbrain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis pathogenetic and clinical implications
    • Kermode A, Thompson A, Tofts P, MacManus D, Kendall B, Kingsley D, et al. Breakdown of the bloodbrain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis Pathogenetic and clinical implications. Brain. 1990; 113(5):1477-89.
    • (1990) Brain , vol.113 , Issue.5 , pp. 1477-1489
    • Kermode, A.1    Thompson, A.2    Tofts, P.3    MacManus, D.4    Kendall, B.5    Kingsley, D.6
  • 68
    • 0028359213 scopus 로고
    • Correlation of magnetization transfer ration with clinical disability in multiple sclerosis
    • PMID: 8024264
    • Gass A, Barker G, Kidd D, Thorpe J, MacManus D, Brennan A, et al. Correlation of magnetization transfer ration with clinical disability in multiple sclerosis. Annals of neurology. 1994; 36(1):62-7. PMID: 8024264.
    • (1994) Annals of Neurology , vol.36 , Issue.1 , pp. 62-67
    • Gass, A.1    Barker, G.2    Kidd, D.3    Thorpe, J.4    MacManus, D.5    Brennan, A.6
  • 69
    • 0033031875 scopus 로고    scopus 로고
    • Correlation between MRI and clinico-pathological manifestations in lewis rats protected from experimental allergic encephalomyelitis by acylated synthetic peptide of myelin basic protein
    • PMID: 10372527
    • Karlik S, Munoz D, St Louis J, Strejan G. Correlation between MRI and clinico-pathological manifestations in Lewis rats protected from experimental allergic encephalomyelitis by acylated synthetic peptide of myelin basic protein. Magnetic resonance imaging. 1999; 17(5):731-7. PMID: 10372527.
    • (1999) Magnetic Resonance Imaging , vol.17 , Issue.5 , pp. 731-737
    • Karlik, S.1    Munoz, D.2    St Louis, J.3    Strejan, G.4
  • 70
    • 34547928758 scopus 로고    scopus 로고
    • Magnetic resonance imaging of blood- spinal cord barrier disruption in mice with experimental autoimmune encephalomyelitis
    • PMID: 17654586
    • Schellenberg AE, Buist R, Yong VW, Del Bigio MR, Peeling J. Magnetic resonance imaging of blood- spinal cord barrier disruption in mice with experimental autoimmune encephalomyelitis. Magnetic Resonance in Medicine. 2007; 58(2):298-305. PMID: 17654586.
    • (2007) Magnetic Resonance in Medicine , vol.58 , Issue.2 , pp. 298-305
    • Schellenberg, A.E.1    Buist, R.2    Yong, V.W.3    Del Bigio, M.R.4    Peeling, J.5
  • 71
    • 0021164553 scopus 로고
    • Blood-brain and blood-spinal cord barrier permeability during the course of experimental allergic encephalomyelitis in the rat
    • PMID: 6610460
    • Juhler M, Barry DI, Offner H, Konat G, Klinken L, Paulson OB. Blood-brain and blood-spinal cord barrier permeability during the course of experimental allergic encephalomyelitis in the rat. Brain research. 1984; 302(2):347-55. PMID: 6610460.
    • (1984) Brain Research , vol.302 , Issue.2 , pp. 347-355
    • Juhler, M.1    Barry, D.I.2    Offner, H.3    Konat, G.4    Klinken, L.5    Paulson, O.B.6
  • 72
    • 0014135669 scopus 로고
    • Brain vascular permeability to i125 gamma globulin and leukocytes in allergic encephalomyelitis
    • Cutler RW, Lorenzo AV, Barlow CF. Brain vascular permeability to I125 gamma globulin and leukocytes in allergic encephalomyelitis. Journal of Neuropathology & Experimental Neurology. 1967; 26(4):558- 71.
    • (1967) Journal of Neuropathology & Experimental Neurology , vol.26 , Issue.4 , pp. 558-571
    • Cutler, R.W.1    Lorenzo, A.V.2    Barlow, C.F.3
  • 73
    • 0015333994 scopus 로고
    • Cerebral vascular permeability and cellular infiltration in experimental allergic encephalomyelitis
    • PMID: 5021707
    • Leibowitz S, Kennedy L. Cerebral vascular permeability and cellular infiltration in experimental allergic encephalomyelitis. Immunology. 1972; 22(5):859. PMID: 5021707.
    • (1972) Immunology , vol.22 , Issue.5 , pp. 859
    • Leibowitz, S.1    Kennedy, L.2
  • 74
    • 0000420103 scopus 로고
    • A study of abnormal blood-brain permeability in experimental allergic encephalomyelitis
    • Barlow CF. A study of abnormal blood-brain permeability in experimental allergic encephalomyelitis. Journal of Neuropathology & Experimental Neurology. 1956; 15(2):196-207.
    • (1956) Journal of Neuropathology & Experimental Neurology , vol.15 , Issue.2 , pp. 196-207
    • Barlow, C.F.1
  • 75
    • 0025906369 scopus 로고
    • Patterns of blood-brain barrier breakdown in inflammatory demyelination
    • Hawkins C, Mackenzie F, Tofts P, Du Boulay E, McDonald W. Patterns of blood-brain barrier breakdown in inflammatory demyelination. Brain. 1991; 114(2):801-10.
    • (1991) Brain , vol.114 , Issue.2 , pp. 801-810
    • Hawkins, C.1    Mackenzie, F.2    Tofts, P.3    Du Boulay, E.4    McDonald, W.5
  • 76
    • 0021367979 scopus 로고
    • Effect of high-dose intravenous steriod administration on contrast-enhancing computed tomographic scan lesions in multiple sclerosis
    • PMID: 6721447
    • Troiano R, Hafstein M, Ruderman M, Dowling P, Cook S. Effect of high-dose intravenous steriod administration on contrast-enhancing computed tomographic scan lesions in multiple sclerosis. Annals of neurology. 1984; 15(3):257-63. PMID: 6721447.
    • (1984) Annals of Neurology , vol.15 , Issue.3 , pp. 257-263
    • Troiano, R.1    Hafstein, M.2    Ruderman, M.3    Dowling, P.4    Cook, S.5
  • 78
    • 34547789342 scopus 로고    scopus 로고
    • Early MRI changes in a mouse model of multiple sclerosis are predictive of severe inflammatory tissue damage
    • Nessler S, Boretius S, Stadelmann C, Bittner A, Merkler D, Hartung H-P, et al. Early MRI changes in a mouse model of multiple sclerosis are predictive of severe inflammatory tissue damage. Brain. 2007; 130(8):2186-98.
    • (2007) Brain , vol.130 , Issue.8 , pp. 2186-2198
    • Nessler, S.1    Boretius, S.2    Stadelmann, C.3    Bittner, A.4    Merkler, D.5    Hartung, H.-P.6
  • 79
    • 0026323045 scopus 로고
    • The pathophysiology of acute optic neuritis an association of gadolinium leakage with clinical and electrophysiological deficits
    • Youl B, Turano G, Miller D, Towell A, MacManus D, Moore S, et al. The pathophysiology of acute optic neuritis An association of gadolinium leakage with clinical and electrophysiological deficits. Brain. 1991; 114(6):2437-50.
    • (1991) Brain , vol.114 , Issue.6 , pp. 2437-2450
    • Youl, B.1    Turano, G.2    Miller, D.3    Towell, A.4    MacManus, D.5    Moore, S.6


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