메뉴 건너뛰기




Volumn 213, Issue 1-2, 2009, Pages 20-25

Pegylated nanoliposomes remote-loaded with the antioxidant tempamine ameliorate experimental autoimmune encephalomyelitis

Author keywords

Antioxidants; EAE; Liposomes; MS; Neurodegeneration; Tempamine

Indexed keywords

AMMONIUM SULFATE; ANTIOXIDANT; CHOLESTEROL ESTER; GAMMA INTERFERON; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LIPOSOME; MACROGOL 2000; N,N,N TRIMETHYLTEMPAMINE; PHOSPHATIDYLETHANOLAMINE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

EID: 68049102034     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2009.05.019     Document Type: Article
Times cited : (73)

References (35)
  • 1
    • 0021722357 scopus 로고
    • Nitroxyl spin label contrast enhancers for magnetic resonance imaging. Studies of acute toxicity and mutagenesis
    • Afzal V., Brasch R.C., Nitecki D.E., and Wolff S. Nitroxyl spin label contrast enhancers for magnetic resonance imaging. Studies of acute toxicity and mutagenesis. Invest. Radiol. 19 (1984) 549-552
    • (1984) Invest. Radiol. , vol.19 , pp. 549-552
    • Afzal, V.1    Brasch, R.C.2    Nitecki, D.E.3    Wolff, S.4
  • 2
    • 38149100039 scopus 로고    scopus 로고
    • Amphipathic weak acid glucocorticoid prodrugs remote-loaded into sterically stabilized nanoliposomes evaluated in arthritic rats and in a Beagle dog: a novel approach to treating autoimmune arthritis
    • Avnir Y., Ulmansky R., Wasserman V., Even-Chen S., Broyer M., Barenholz Y., and Naparstek Y. Amphipathic weak acid glucocorticoid prodrugs remote-loaded into sterically stabilized nanoliposomes evaluated in arthritic rats and in a Beagle dog: a novel approach to treating autoimmune arthritis. Arthritis Rheum. 58 (2008) 119-129
    • (2008) Arthritis Rheum. , vol.58 , pp. 119-129
    • Avnir, Y.1    Ulmansky, R.2    Wasserman, V.3    Even-Chen, S.4    Broyer, M.5    Barenholz, Y.6    Naparstek, Y.7
  • 3
    • 0003038975 scopus 로고
    • Gregoriadis G. (Ed), CRC Press, Boca Raton
    • Barenholz Y. In: Gregoriadis G. (Ed). Liposome Technology vol. I (1993), CRC Press, Boca Raton 527-616
    • (1993) Liposome Technology , vol.I , pp. 527-616
    • Barenholz, Y.1
  • 4
    • 0036027864 scopus 로고    scopus 로고
    • Cholesterol and other membrane active sterols: from membrane evolution to "rafts"
    • Barenholz Y. Cholesterol and other membrane active sterols: from membrane evolution to "rafts". Prog. Lipid Res. 41 (2002) 1-5
    • (2002) Prog. Lipid Res. , vol.41 , pp. 1-5
    • Barenholz, Y.1
  • 5
    • 0037231460 scopus 로고    scopus 로고
    • Relevancy of drug loading to liposomal formulation therapeutic efficacy
    • Barenholz Y. Relevancy of drug loading to liposomal formulation therapeutic efficacy. J. Liposome. Res. 13 (2003) 1-8
    • (2003) J. Liposome. Res. , vol.13 , pp. 1-8
    • Barenholz, Y.1
  • 6
    • 52949123670 scopus 로고    scopus 로고
    • Amphipathic weak base loading into preformed liposomes having a transmembrane ammonium ion gradient: from the bench to approved DOXIL
    • Gregoriadis G. (Ed), CRC Press, Boca Raton
    • Barenholz Y. Amphipathic weak base loading into preformed liposomes having a transmembrane ammonium ion gradient: from the bench to approved DOXIL. In: Gregoriadis G. (Ed). Liposome Technology vol. 26 (2007), CRC Press, Boca Raton 1-26
    • (2007) Liposome Technology , vol.26 , pp. 1-26
    • Barenholz, Y.1
  • 10
    • 0029557647 scopus 로고
    • Loading of amphipathic weak acids into liposomes in response to transmembrane calcium acetate gradients
    • Clerc S., and Barenholz Y. Loading of amphipathic weak acids into liposomes in response to transmembrane calcium acetate gradients. Biochim. Biophys. Acta 1240 (1995) 257-265
    • (1995) Biochim. Biophys. Acta , vol.1240 , pp. 257-265
    • Clerc, S.1    Barenholz, Y.2
  • 11
    • 0026671446 scopus 로고
    • Nitroxide-mediated protection against X-ray-and neocarzinostatin-induced DNA damage
    • DeGraff W.G., Krishna M.C., Kaufman D., and Mitchell J.B. Nitroxide-mediated protection against X-ray-and neocarzinostatin-induced DNA damage. Free Radic. Biol. Med. 13 (1992) 479-487
    • (1992) Free Radic. Biol. Med. , vol.13 , pp. 479-487
    • DeGraff, W.G.1    Krishna, M.C.2    Kaufman, D.3    Mitchell, J.B.4
  • 12
    • 0030001780 scopus 로고    scopus 로고
    • Oxidative stress and antioxidant therapy in Parkinson's disease
    • Ebadi M., Srinivasan S.K., and Baxi M.D. Oxidative stress and antioxidant therapy in Parkinson's disease. Prog. Neurobiol. 48 (1996) 1-19
    • (1996) Prog. Neurobiol. , vol.48 , pp. 1-19
    • Ebadi, M.1    Srinivasan, S.K.2    Baxi, M.D.3
  • 14
    • 0028349925 scopus 로고
    • Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes
    • Gabizon A., Catane R., Uziely B., Kaufman B., Safra T., Cohen R., Martin F., Huang A., and Barenholz Y. Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes. Cancer Res. 54 (1994) 987-992
    • (1994) Cancer Res. , vol.54 , pp. 987-992
    • Gabizon, A.1    Catane, R.2    Uziely, B.3    Kaufman, B.4    Safra, T.5    Cohen, R.6    Martin, F.7    Huang, A.8    Barenholz, Y.9
  • 15
    • 0034796353 scopus 로고    scopus 로고
    • Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment
    • Halliwell B. Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment. Drugs Aging 18 (2001) 685-716
    • (2001) Drugs Aging , vol.18 , pp. 685-716
    • Halliwell, B.1
  • 16
    • 0027514941 scopus 로고
    • Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases
    • Haran G., Cohen R., Bar L.K., and Barenholz Y. Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases. Biochim. Biophys. Acta 1151 (1993) 201-215
    • (1993) Biochim. Biophys. Acta , vol.1151 , pp. 201-215
    • Haran, G.1    Cohen, R.2    Bar, L.K.3    Barenholz, Y.4
  • 17
    • 0025015655 scopus 로고
    • Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages
    • Huitinga I., van Rooijen N., de Groot C.J., Uitdehaag B.M., and Dijkstra C.D. Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages. J. Exp. Med. 172 (1990) 1025-1033
    • (1990) J. Exp. Med. , vol.172 , pp. 1025-1033
    • Huitinga, I.1    van Rooijen, N.2    de Groot, C.J.3    Uitdehaag, B.M.4    Dijkstra, C.D.5
  • 18
    • 0028242318 scopus 로고
    • Delivery of cytokines by liposomes. I. Preparation and characterization of interleukin-2 encapsulated in long-circulating sterically stabilized liposomes
    • Kedar E., Rutkowski Y., Braun E., Emanuel N., and Barenholz Y. Delivery of cytokines by liposomes. I. Preparation and characterization of interleukin-2 encapsulated in long-circulating sterically stabilized liposomes. J. Immunother. Emphasis. Tumor Immunol. 16 (1994) 47-59
    • (1994) J. Immunother. Emphasis. Tumor Immunol. , vol.16 , pp. 47-59
    • Kedar, E.1    Rutkowski, Y.2    Braun, E.3    Emanuel, N.4    Barenholz, Y.5
  • 20
    • 0034662806 scopus 로고    scopus 로고
    • Oxidative damage to mitochondrial DNA and activity of mitochondrial enzymes in chronic active lesions of multiple sclerosis
    • Lu F., Selak M., O'Connor J., Croul S., Lorenzana C., Butunoi C., and Kalman B. Oxidative damage to mitochondrial DNA and activity of mitochondrial enzymes in chronic active lesions of multiple sclerosis. J. Neurol. Sci. 177 (2000) 95-103
    • (2000) J. Neurol. Sci. , vol.177 , pp. 95-103
    • Lu, F.1    Selak, M.2    O'Connor, J.3    Croul, S.4    Lorenzana, C.5    Butunoi, C.6    Kalman, B.7
  • 21
    • 0032902974 scopus 로고    scopus 로고
    • Oxidative alterations in Alzheimer's disease
    • Markesbery W.R., and Carney J.M. Oxidative alterations in Alzheimer's disease. Brain Pathol. 9 (1999) 133-146
    • (1999) Brain Pathol. , vol.9 , pp. 133-146
    • Markesbery, W.R.1    Carney, J.M.2
  • 24
    • 13844293971 scopus 로고    scopus 로고
    • Blood-brain barrier disruption and lesion localisation in experimental autoimmune encephalomyelitis with predominant cerebellar and brainstem involvement
    • Muller D.M., Pender M.P., and Greer J.M. Blood-brain barrier disruption and lesion localisation in experimental autoimmune encephalomyelitis with predominant cerebellar and brainstem involvement. J. Neuroimmunol. 160 (2005) 162-169
    • (2005) J. Neuroimmunol. , vol.160 , pp. 162-169
    • Muller, D.M.1    Pender, M.P.2    Greer, J.M.3
  • 25
    • 0034455884 scopus 로고    scopus 로고
    • Mice overexpressing Bcl-2 in their neurons are resistant to myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE)
    • Offen D., Kaye J.F., Bernard O., Merims D., Coire C.I., Panet H., Melamed E., and Ben-Nun A. Mice overexpressing Bcl-2 in their neurons are resistant to myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE). J. Mol. Neurosci. 15 (2000) 167-176
    • (2000) J. Mol. Neurosci. , vol.15 , pp. 167-176
    • Offen, D.1    Kaye, J.F.2    Bernard, O.3    Merims, D.4    Coire, C.I.5    Panet, H.6    Melamed, E.7    Ben-Nun, A.8
  • 26
    • 0035830628 scopus 로고    scopus 로고
    • Characterization of sterically stabilized cisplatin liposomes by nuclear magnetic resonance
    • Peleg-Shulman T., Gibson D., Cohen R., Abra R., and Barenholz Y. Characterization of sterically stabilized cisplatin liposomes by nuclear magnetic resonance. Biochim. Biophys. Acta 1510 (2001) 278-291
    • (2001) Biochim. Biophys. Acta , vol.1510 , pp. 278-291
    • Peleg-Shulman, T.1    Gibson, D.2    Cohen, R.3    Abra, R.4    Barenholz, Y.5
  • 27
    • 0345700315 scopus 로고    scopus 로고
    • The EAE-associated behavioral syndrome: I. Temporal correlation with inflammatory mediators
    • Pollak Y., Ovadia H., Orion E., Weidenfeld J., and Yirmiya R. The EAE-associated behavioral syndrome: I. Temporal correlation with inflammatory mediators. J. Neuroimmunol. 137 (2003) 94-99
    • (2003) J. Neuroimmunol. , vol.137 , pp. 94-99
    • Pollak, Y.1    Ovadia, H.2    Orion, E.3    Weidenfeld, J.4    Yirmiya, R.5
  • 29
    • 0038448961 scopus 로고    scopus 로고
    • Upregulation of expression from the FRDA genomic locus for the therapy of Friedreich ataxia
    • Sarsero J.P., Li L., Wardan H., Sitte K., Williamson R., and Ioannou P.A. Upregulation of expression from the FRDA genomic locus for the therapy of Friedreich ataxia. J. Genet. Med. 5 (2003) 72-81
    • (2003) J. Genet. Med. , vol.5 , pp. 72-81
    • Sarsero, J.P.1    Li, L.2    Wardan, H.3    Sitte, K.4    Williamson, R.5    Ioannou, P.A.6
  • 30
    • 0043268760 scopus 로고    scopus 로고
    • Drug targeting by long-circulating liposomal glucocorticosteroids increases therapeutic efficacy in a model of multiple sclerosis
    • Schmidt J., Metselaar J.M., Wauben M.H., Toyka K.V., Storm G., and Gold R. Drug targeting by long-circulating liposomal glucocorticosteroids increases therapeutic efficacy in a model of multiple sclerosis. Brain 126 (2003) 1895-1904
    • (2003) Brain , vol.126 , pp. 1895-1904
    • Schmidt, J.1    Metselaar, J.M.2    Wauben, M.H.3    Toyka, K.V.4    Storm, G.5    Gold, R.6
  • 31
    • 0242317879 scopus 로고    scopus 로고
    • Enzymatic assays for quality control and pharmacokinetics of liposome formulations: comparison with nonenzymatic conventional methodologies
    • Shmeeda H., Even-Chen S., Honen R., Cohen R., Weintraub C., and Barenholz Y. Enzymatic assays for quality control and pharmacokinetics of liposome formulations: comparison with nonenzymatic conventional methodologies. Methods Enzymol. 367 (2003) 272-292
    • (2003) Methods Enzymol. , vol.367 , pp. 272-292
    • Shmeeda, H.1    Even-Chen, S.2    Honen, R.3    Cohen, R.4    Weintraub, C.5    Barenholz, Y.6
  • 32
    • 0025240016 scopus 로고
    • Suppression of experimental allergic encephalomyelitis by MBP-coupled lymphoid cells and by MBP-liposomes: a comparison
    • Strejan G.H., and St Louis J. Suppression of experimental allergic encephalomyelitis by MBP-coupled lymphoid cells and by MBP-liposomes: a comparison. Cell. Immunol. 127 (1990) 284-298
    • (1990) Cell. Immunol. , vol.127 , pp. 284-298
    • Strejan, G.H.1    St Louis, J.2
  • 33
    • 0035966659 scopus 로고    scopus 로고
    • Comparison of the timing of acute blood-brain barrier breakdown to rabbit immunoglobulin G in the cerebellum and spinal cord of mice with experimental autoimmune encephalomyelitis
    • Tonra J.R., Reiseter B.S., Kolbeck R., Nagashima K., Robertson R., Keyt B., and Lindsay R.M. Comparison of the timing of acute blood-brain barrier breakdown to rabbit immunoglobulin G in the cerebellum and spinal cord of mice with experimental autoimmune encephalomyelitis. J. Comp. Neurol. 430 (2001) 131-144
    • (2001) J. Comp. Neurol. , vol.430 , pp. 131-144
    • Tonra, J.R.1    Reiseter, B.S.2    Kolbeck, R.3    Nagashima, K.4    Robertson, R.5    Keyt, B.6    Lindsay, R.M.7
  • 34
    • 33947123224 scopus 로고    scopus 로고
    • The antioxidant tempamine: in vitro antitumor and neuroprotective effects and optimization of liposomal encapsulation and release
    • Wasserman V., Kizelsztein P., Garbuzenko O., Kohen R., Ovadia H., Tabakman R., and Barenholz Y. The antioxidant tempamine: in vitro antitumor and neuroprotective effects and optimization of liposomal encapsulation and release. Langmuir 23 (2007) 1937-1947
    • (2007) Langmuir , vol.23 , pp. 1937-1947
    • Wasserman, V.1    Kizelsztein, P.2    Garbuzenko, O.3    Kohen, R.4    Ovadia, H.5    Tabakman, R.6    Barenholz, Y.7
  • 35
    • 0019860712 scopus 로고
    • Liposomes containing myelin basic protein (BP) suppress but do not induce allergic encephalomyelitis in Lewis rats
    • Willenborg D.O., and Higgins T.J. Liposomes containing myelin basic protein (BP) suppress but do not induce allergic encephalomyelitis in Lewis rats. Aust. J. Exp. Biol. Med. Sci. 59 (1981) 135-141
    • (1981) Aust. J. Exp. Biol. Med. Sci. , vol.59 , pp. 135-141
    • Willenborg, D.O.1    Higgins, T.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.