Liposome application: Problems and prospects

Current Opinion in Colloid and Interface Science

Volumn 6, Issue 1, 2001, Pages 66-77

  Barenholz, Yechezkel ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Ammonium sulfate gradients; DOXIL; Lipoplexes; Lipopolymers; Liposome remote loading (active loading); Liposome remote release; PEGylated lipids; Sterically stabilized liposomes

Indexed keywords

AMMONIUM SULFATE; CATION; COSMETIC; ION; LIPID; LIPOSOME; NUCLEIC ACID; PROTEIN;

BLOOD BRAIN BARRIER; DRUG RELEASE; DRUG RESEARCH; MATERIALS; MOLECULAR STABILITY; PERMEABILITY BARRIER; PH; PHARMACEUTICAL ENGINEERING; PHYSICAL CHEMISTRY; REVIEW; SKIN;

EID: 0035085192     PISSN: 13590294     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-0294(00)00090-X     Document Type: Review

References (71)

1. Liposomes in cosmetics: How and why?
2. The accumulation of drugs within large unilamellar vesicles exhibiting a proton gradient: A survey
3. Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases
4. Liposomes: Efficient loading and controlled release of amphipathic molecules
5. Liposomal anthracyclines - From basics to clinical approval of PEGylated liposomal doxorubicin
6. Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes
7. Development of liposomal anthracyclines: From basics to clinical applications
8. Selective delivery of doxorubicin to patients with breast carcinoma metastases by Stealth liposomes
9. Sterically stabilized liposomes in cancer therapy and gene delivery
10. Design of liposome-based drug carriers: From basic research to application as approved drugs
11. Ammonium sulfate gradients for efficient and stable remote loading of amphipathic weak bases into liposomes and ligandoliposomes
12. Gelation of liposome interior. A novel method for drug encapsulation
13. Transmembrane gradient driven phase transitions within vesicles: Lessons for drug delivery
14. A quantitative model for using acridine orange as a transmembrane pH gradient probe
15. Rational design of amphiphile-based drug carriers and sterically stabilized carriers
16. Stability of liposomal-doxorubicin formulation: Problems and prospects
17. In vitro cytotoxicity of liposome-encapsulated doxorubicin: Dependence on liposome composition and drug release
18. Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump
19. Structure and properties of membranes
20. DRV liposomal bupivacaine: Preparation, characterization, and in vivo evaluation in mice
21. A new look at lipid-membrane structure in relation to drug research
22. In search for new biomembrane model
23. Dynamical order and disorder in lipid bilayers
24. Damage to liposomal lipids: Protection by antioxidants and cholesterol-mediated dehydration
25. Hydration of polyethylene glycol-grafted liposomes
26. The role of hydration in stabilization of liposomes; resistance to oxidative damage of PEG-grafted liposomes
27. Novel synthetic phospholipid protects lipid bilayers against oxidative damage: Role of hydration layer and bound water
28. Pharmacological studies of cisplatin encapsulated in long-circulating liposomes in mouse tumor models
29. A new temperature-sensitive liposome for use with mild hyperthermia: Characterization and testing in human tumor xenograft model
30. Liposomes with detachable polymer coating: Destabilization and fusion of dioleoylphosphatidyl-ethanolamine vesicles triggered by cleavage of surface grafted poly(ethylene glycol)
31. New detachable poly(ethylene glycol) conjugates: Cysteine-cleavable lipopolymers regenerating natural phospholipid, diacyl phosphatidylethanol amine
32. Radiolabeled liposomes for scintigraphic imaging
33. The use of scintigraphic imaging as a tool in the development of liposome formulations
34. Pharmacokinetic and imaging studies in patients receiving a formulation of liposome-associated adriamycin
35. An improved method for in vivo tracing and imaging of liposomes using a gallium-67-deferoxamine complex
36. Targeted delivery of doxorubicin via sterically stabilized immunoliposomes: Pharmacokinetics and biodistribution in tumor-bearing mice
37. Targeting of Stealth liposomes to erbB-2 (Her/2) receptor: In vitro and in vivo studies
38. An analysis of monoclonal antibody distribution in microscopic tumor nodules: Consequences of a 'binding site barrier'
39. Immunogenicity of immunoliposomes
40. Immunogenicity and pharmacokinetic attributes of poly(ethylene glycol)-grafted immunoliposomes
41. Development and characterization of novel vaccines against influenza based on liposome-entrapped viral antigens and cytokines
42. Development anti-p185HER2 immunoliposomes for cancer therapy
43. Targeting of sterically-stabilized liposomes to cancer expressing HER2/neu proto-oncogene
44. A novel strategy affording high yield coupling of antibodies to extremities of liposomal-grafted PEG chains
45. Antiproliferative effect of immunoliposomes containing 5-fluoro-deoxyuridine-dipalmitate on colon cancer cells
46. Selective targeting of immunoliposomal doxorubicin against human multiple myeloma in vitro and ex vivo
47. Targeting of endothelial KDR receptors with 3G2 immunoliposomes in vitro
48. Targeted drug delivery via folate receptor
49. Delivery of liposomes into KB cells via folate receptor-mediated endocytosis
50. Targeting folate receptor with folate linked to extremities of poly(ethylene glycol)-grafted liposomes: In vitro studies
51. Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump
52. Nomenclature for synthetic gene delivery systems
53. Lipofectin: A highly efficient lipid-mediated DNA transfection procedure
54. Comparison of different commercially available cationic lipid-based transfection kits
55. Direct evidence for counterion release upon cationic lipid-DNA condensation
56. Electrostatic and structural properties of plasmid DNA-lipid complexes commonly used for gene delivery
57. Lamellarity of cationic liposomes and mode of preparation of lipoplexes affect transfection efficiency
58. Structure and fusogenic properties of cationic liposomes in the presence of plasmid DNA
59. Probing DNA-cationic lipid interactions with the fluorophore trimethylammonium diphenyl-hexatriene (TMADPH)
60. Phase diagram, stability, and overcharging of lamellar cationic lipid-DNA self-assembled lipoplexes
61. The phase behavior of cationic lipid-DNA complexes
62. Hierarchical self-assembly of F-actin and cationic lipid complexes: Stacked three-layer tubule networks
63. How are nucleic acids released in cells from cationic lipid-nucleic acid complexes?
64. Characterization of sterically stabilized cisplatin liposomes by nuclear magnetic resonance