Optimizing the therapeutic index of liposomal glucocorticoids in experimental arthritis

International Journal of Pharmaceutics

Volumn 416, Issue 2, 2011, Pages 471-477

  Van Den Hoven, Jolanda M ^a,b   Hofkens, Wouter ^c   Wauben, Marca H M ^d   Wagenaar Hilbers, Josee P A ^d   Beijnen, Jos H ^a,b   Nuijen, Bastiaan ^a   Metselaar, Josbert M ^b   Storm, Gert ^b  

^a SLOTERVAART HOSPITAL   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Glucocorticoids; Liposomes; Rheumatoid arthritis; Targetting; Therapeutic index

Indexed keywords

BUDESONIDE; DEXAMETHASONE SODIUM PHOSPHATE; MACROGOL 2000; PREDNISOLONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTHRITIS; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DRUG CLEARANCE; DRUG EFFICACY; DRUG POTENCY; DRUG SAFETY; DRUG TARGETING; ENCAPSULATION; HYPERGLYCEMIA; LIPOSOMAL DELIVERY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; TREATMENT RESPONSE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, EXPERIMENTAL; BODY WEIGHT; BUDESONIDE; DEXAMETHASONE; GLUCOCORTICOIDS; HYPERGLYCEMIA; LIPOSOMES; MALE; PARTICLE SIZE; PREDNISOLONE; RATS; RATS, INBRED LEW;

EID: 79961083445     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.03.025     Document Type: Article

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