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Volumn 40, Issue 5, 2015, Pages 875-884

Vitamin C Neuroprotection Against Dose-Dependent Glutamate-Induced Neurodegeneration in the Postnatal Brain

Author keywords

AMPK; Excitotoxicity; Glutamate; Neuroprotection; Vitamin C

Indexed keywords

ASCORBIC ACID; GLUTAMIC ACID; NEUROPROTECTIVE AGENT;

EID: 84939957292     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-015-1540-2     Document Type: Article
Times cited : (47)

References (49)
  • 1
    • 0029091060 scopus 로고
    • Biochemical changes associated with selective neuronal death following short-term cerebral ischaemia
    • COI: 1:CAS:528:DyaK2MXnsVShsbc%3D, PID: 7671133
    • Sims NR, Zaidan E (1995) Biochemical changes associated with selective neuronal death following short-term cerebral ischaemia. Int J Biochem Cell Biol 27:531–550
    • (1995) Int J Biochem Cell Biol , vol.27 , pp. 531-550
    • Sims, N.R.1    Zaidan, E.2
  • 2
    • 0028762647 scopus 로고
    • Excitatory amino acids as a final common pathway for neurologic disorder
    • COI: 1:CAS:528:DyaK2cXltVGhtbk%3D, PID: 7905600
    • Lipton SA, Rosenberg PA (1994) Excitatory amino acids as a final common pathway for neurologic disorder. N Engl J Med 330:613–622
    • (1994) N Engl J Med , vol.330 , pp. 613-622
    • Lipton, S.A.1    Rosenberg, P.A.2
  • 3
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate, and neurodegenerative disorders
    • COI: 1:CAS:528:DyaK2cXlvVek, PID: 7901908
    • Coyle JT, Puttfarcken P (1993) Oxidative stress, glutamate, and neurodegenerative disorders. Science 262:689–695
    • (1993) Science , vol.262 , pp. 689-695
    • Coyle, J.T.1    Puttfarcken, P.2
  • 4
    • 34047100940 scopus 로고    scopus 로고
    • N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington’s disease
    • COI: 1:CAS:528:DC%2BD2sXjvFGqtLw%3D, PID: 17188796
    • Fan MMY, Raymond LA (2007) N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington’s disease. Prog Neurobiol 81:272–293
    • (2007) Prog Neurobiol , vol.81 , pp. 272-293
    • Fan, M.M.Y.1    Raymond, L.A.2
  • 5
    • 57749170753 scopus 로고    scopus 로고
    • Augmentation of nitrite therapy in cerebral ischemia by NMDA receptor inhibition
    • COI: 1:CAS:528:DC%2BD1cXhsFClsrrL, PID: 19056343
    • Jung KH, Chu K, Lee ST, Park HK, Kim JH, Kang KM (2009) Augmentation of nitrite therapy in cerebral ischemia by NMDA receptor inhibition. Biochem Biophys Res Comm 378:507–512
    • (2009) Biochem Biophys Res Comm , vol.378 , pp. 507-512
    • Jung, K.H.1    Chu, K.2    Lee, S.T.3    Park, H.K.4    Kim, J.H.5    Kang, K.M.6
  • 6
    • 57649178152 scopus 로고    scopus 로고
    • Role of N-methyl-D-aspartate receptors in polychlorinated biphenyl mediated neurotoxicity
    • COI: 1:CAS:528:DC%2BD1cXhsFagtrnF, PID: 19022367
    • Ndountse LT, Chan HM (2009) Role of N-methyl-D-aspartate receptors in polychlorinated biphenyl mediated neurotoxicity. Toxicol Lett 184:50–55
    • (2009) Toxicol Lett , vol.184 , pp. 50-55
    • Ndountse, L.T.1    Chan, H.M.2
  • 7
    • 0030052530 scopus 로고    scopus 로고
    • Requirement for superoxide in excitotoxic cell death
    • COI: 1:CAS:528:DyaK28XhtlGhsLc%3D, PID: 8789949
    • Patel M, Day BJ, Crapo JD, Fridovich I, McNamara JO (1996) Requirement for superoxide in excitotoxic cell death. Neuron 16:345–355
    • (1996) Neuron , vol.16 , pp. 345-355
    • Patel, M.1    Day, B.J.2    Crapo, J.D.3    Fridovich, I.4    McNamara, J.O.5
  • 8
    • 2642542621 scopus 로고    scopus 로고
    • Equine estrogens differentially inhibit DNA fragmentation induced by glutamate in neuronal cells by modulation of regulatory proteins involved in programmed cell death
    • PID: 14693041
    • Zhang YM, Lu XF, Bhavnani BR (2003) Equine estrogens differentially inhibit DNA fragmentation induced by glutamate in neuronal cells by modulation of regulatory proteins involved in programmed cell death. BMC Neurosci 4:32
    • (2003) BMC Neurosci , vol.4 , pp. 32
    • Zhang, Y.M.1    Lu, X.F.2    Bhavnani, B.R.3
  • 9
    • 26444580828 scopus 로고    scopus 로고
    • Glutamate-induced apoptosis in primary cortical neurons is inhibited by equine estrogens via down-regulation of caspase-3 and prevention of mitochondrial cytochrome c release
    • PID: 15730564
    • Zhang YM, Bhavnani BR (2005) Glutamate-induced apoptosis in primary cortical neurons is inhibited by equine estrogens via down-regulation of caspase-3 and prevention of mitochondrial cytochrome c release. BMC Neurosci 6:13
    • (2005) BMC Neurosci , vol.6 , pp. 13
    • Zhang, Y.M.1    Bhavnani, B.R.2
  • 11
    • 33745199458 scopus 로고    scopus 로고
    • AMPK-activated protein kinase as a multifunctional metabolic sensor in the brain
    • COI: 1:CAS:528:DC%2BD28XnsVyju7g%3D, PID: 16690704
    • Ramamurthy S, Ronnett GV (2006) AMPK-activated protein kinase as a multifunctional metabolic sensor in the brain. J Physiol 574:85–93
    • (2006) J Physiol , vol.574 , pp. 85-93
    • Ramamurthy, S.1    Ronnett, G.V.2
  • 12
    • 33745225026 scopus 로고    scopus 로고
    • AMP-activated protein kinase development of the energy sensor concept
    • COI: 1:CAS:528:DC%2BD28XnsVyjurc%3D, PID: 16644800
    • Hardie DG, Hawley SA, Scott JW (2006) AMP-activated protein kinase development of the energy sensor concept. J Physiol 574:7–15
    • (2006) J Physiol , vol.574 , pp. 7-15
    • Hardie, D.G.1    Hawley, S.A.2    Scott, J.W.3
  • 13
    • 77956780170 scopus 로고    scopus 로고
    • Metabolism of vitamin C in health and disease
    • COI: 1:CAS:528:DyaK2sXivVamtA%3D%3D, PID: 8895802
    • Bode AM (1997) Metabolism of vitamin C in health and disease. Adv Pharmacol 38:21
    • (1997) Adv Pharmacol , vol.38 , pp. 21
    • Bode, A.M.1
  • 15
    • 12244289625 scopus 로고    scopus 로고
    • Vitamin C as an antioxidant: evaluation of its role in disease prevention
    • Padayatti SJ, Katz A, Wang Y, Eck P, Kwon O, Lee J (2003) Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr 22:18–35
    • (2003) J Am Coll Nutr , vol.22 , pp. 18-35
    • Padayatti, S.J.1    Katz, A.2    Wang, Y.3    Eck, P.4    Kwon, O.5    Lee, J.6
  • 16
    • 0025340706 scopus 로고
    • Free radicals and antioxidant systems in health and disease
    • COI: 1:STN:280:DyaK3czgsVCkuw%3D%3D, PID: 2194616
    • Sinclair AJ, Barnett AH, Lunec J (1990) Free radicals and antioxidant systems in health and disease. Br J Hosp Med 43:334–344
    • (1990) Br J Hosp Med , vol.43 , pp. 334-344
    • Sinclair, A.J.1    Barnett, A.H.2    Lunec, J.3
  • 17
    • 33746383473 scopus 로고    scopus 로고
    • Ascorbate transport and recycling by SH-SY5Y neuroblastoma cells: response to glutamate toxicity
    • COI: 1:CAS:528:DC%2BD28Xnt1ait7s%3D, PID: 16791474
    • May MJ, Li L, Hayslett K, Qu Z (2006) Ascorbate transport and recycling by SH-SY5Y neuroblastoma cells: response to glutamate toxicity. Neurochem Res 31:785–794
    • (2006) Neurochem Res , vol.31 , pp. 785-794
    • May, M.J.1    Li, L.2    Hayslett, K.3    Qu, Z.4
  • 18
    • 33646395679 scopus 로고    scopus 로고
    • Agmatine protects against cell damage induced by NMDA and glutamate in cultured hippocampal neurons
    • COI: 1:CAS:528:DC%2BD28Xks1WltLo%3D, PID: 16546145
    • Wang WP, Iyo AH, Miguel-Hidalgo J, Regunathan S, Zhu MY (2006) Agmatine protects against cell damage induced by NMDA and glutamate in cultured hippocampal neurons. Brain Res 1084:210–216
    • (2006) Brain Res , vol.1084 , pp. 210-216
    • Wang, W.P.1    Iyo, A.H.2    Miguel-Hidalgo, J.3    Regunathan, S.4    Zhu, M.Y.5
  • 19
    • 0025542381 scopus 로고
    • Ascorbic acid protects neurons from injury induced by glutamate and NMDA
    • COI: 1:CAS:528:DyaK38XkvVehu70%3D, PID: 1983355
    • Majewska MD, Bell JA (1990) Ascorbic acid protects neurons from injury induced by glutamate and NMDA. NeuroReport 1:194–196
    • (1990) NeuroReport , vol.1 , pp. 194-196
    • Majewska, M.D.1    Bell, J.A.2
  • 20
    • 84940281577 scopus 로고    scopus 로고
    • Protection of the developing brain with anthocyanins against ethanol-induced oxidative stress and neurodegeneration
    • Shah SA, Yoon GH, Kim MO (2014) Protection of the developing brain with anthocyanins against ethanol-induced oxidative stress and neurodegeneration. Mol Neurobiol. doi:10.1007/s12035-014-8805-7
    • (2014) Mol Neurobiol
    • Shah, S.A.1    Yoon, G.H.2    Kim, M.O.3
  • 21
    • 84880923702 scopus 로고    scopus 로고
    • Anthocyanins protect against ethanol-induced neuronal apoptosis via GABAB1 receptors intracellular signaling in prenatal rat hippocampal neurons
    • Shah SA et al (2013) Anthocyanins protect against ethanol-induced neuronal apoptosis via GABAB1 receptors intracellular signaling in prenatal rat hippocampal neurons. Mol Neurobiol 48:257–269
    • (2013) Mol Neurobiol , vol.48 , pp. 257-269
    • Shah, S.A.1
  • 22
    • 84934271980 scopus 로고    scopus 로고
    • Novel osmotin attenuates glutamate-induced synaptic dysfunction and neurodegeneration via the JNK/PI3K/Akt pathway in postnatal rat brain
    • Shahid AS, Hae YL, Ray AB, Dae JY, Myeong OK (2014) Novel osmotin attenuates glutamate-induced synaptic dysfunction and neurodegeneration via the JNK/PI3K/Akt pathway in postnatal rat brain. Cell Death Dis 5:1–10
    • (2014) Cell Death Dis , vol.5 , pp. 1-10
    • Shahid, A.S.1    Hae, Y.L.2    Ray, A.B.3    Dae, J.Y.4    Myeong, O.K.5
  • 23
    • 80053615952 scopus 로고    scopus 로고
    • Protective effect of pyruvate against ethanol-induced apoptotic neurodegeneration in the developing rat brain
    • COI: 1:CAS:528:DC%2BC3MXht12ktbfM, PID: 21803053
    • Ullah N, Naseer MI, Ullah I, Lee HY, Koh PO, Kim MO (2011) Protective effect of pyruvate against ethanol-induced apoptotic neurodegeneration in the developing rat brain. Neuropharmacology 61:1248–1255
    • (2011) Neuropharmacology , vol.61 , pp. 1248-1255
    • Ullah, N.1    Naseer, M.I.2    Ullah, I.3    Lee, H.Y.4    Koh, P.O.5    Kim, M.O.6
  • 24
    • 0141595265 scopus 로고    scopus 로고
    • Glutamate and the glutamate receptor system: a target for drug action
    • PID: 12973748
    • Bleich S, Romer K, Wiltfang J, Kornhuber J (2003) Glutamate and the glutamate receptor system: a target for drug action. Int J Geriatr Psychiatry 18:S33–S40
    • (2003) Int J Geriatr Psychiatry , vol.18 , pp. 33-40
    • Bleich, S.1    Romer, K.2    Wiltfang, J.3    Kornhuber, J.4
  • 25
    • 0345830631 scopus 로고    scopus 로고
    • Physiological roles and therapeutic potential of Metabotropic glutamate receptors
    • COI: 1:CAS:528:DC%2BD2cXptlGktg%3D%3D, PID: 14684432
    • Conn PJ (2003) Physiological roles and therapeutic potential of Metabotropic glutamate receptors. Ann N Y Acad Sci 1003:12–21
    • (2003) Ann N Y Acad Sci , vol.1003 , pp. 12-21
    • Conn, P.J.1
  • 26
    • 0023137252 scopus 로고
    • Ionic dependence of glutamate neurotoxicity
    • COI: 1:CAS:528:DyaL2sXhtFCisb0%3D, PID: 2880938
    • Choi DW (1987) Ionic dependence of glutamate neurotoxicity. J Neurosci 7:369–379
    • (1987) J Neurosci , vol.7 , pp. 369-379
    • Choi, D.W.1
  • 27
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function
    • COI: 1:CAS:528:DyaK2MXptV2gsLc%3D, PID: 7576644
    • Ankarcrona M, Dypbukt JM, Bonfoco E, Zhivotovsky B, Orrenius S, Lipton SA, Nicotera P (1995) Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15:961–973
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3    Zhivotovsky, B.4    Orrenius, S.5    Lipton, S.A.6    Nicotera, P.7
  • 28
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • COI: 1:CAS:528:DyaK3sXhtl2qtL4%3D, PID: 1361523
    • Choi DW (1992) Excitotoxic cell death. J Neurobiol 23:1261–1276
    • (1992) J Neurobiol , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 29
    • 0025773785 scopus 로고
    • Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures
    • COI: 1:CAS:528:DyaK3MXltVyis7s%3D, PID: 1648740
    • Dawson VL, Dawson TM, London ED, Bredt DS, Snyder SH (1991) Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures. Proc Natl Acad Sci USA 88:6368–6371
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 6368-6371
    • Dawson, V.L.1    Dawson, T.M.2    London, E.D.3    Bredt, D.S.4    Snyder, S.H.5
  • 30
    • 0032509776 scopus 로고    scopus 로고
    • Direct evidence for the role of nitric oxide on the glutamate-induced neuronal death in cultured cortical neurons
    • COI: 1:CAS:528:DyaK1cXlsV2ktQ%3D%3D, PID: 9507156
    • Yamauchi M, Omote K, Ninomiya T (1998) Direct evidence for the role of nitric oxide on the glutamate-induced neuronal death in cultured cortical neurons. Brain Res 780:253–259
    • (1998) Brain Res , vol.780 , pp. 253-259
    • Yamauchi, M.1    Omote, K.2    Ninomiya, T.3
  • 31
    • 0034023864 scopus 로고    scopus 로고
    • Molecular mechanisms of calcium-dependent excitotoxicity
    • COI: 1:CAS:528:DC%2BD3cXisFWlsL4%3D, PID: 10759025
    • Sattler R, Tymianski M (2000) Molecular mechanisms of calcium-dependent excitotoxicity. J Mol Med 78:3–13
    • (2000) J Mol Med , vol.78 , pp. 3-13
    • Sattler, R.1    Tymianski, M.2
  • 32
    • 0033635904 scopus 로고    scopus 로고
    • Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system
    • Bibel M, Barde YA (2000) Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system. Genes Dev 14:19–2937
    • (2000) Genes Dev , vol.14 , pp. 19-2937
    • Bibel, M.1    Barde, Y.A.2
  • 33
    • 0034770695 scopus 로고    scopus 로고
    • Selective vulnerability of embryonic cell populations to ethanol-induced apoptosis: implications for alcohol-related birth defects and neurodevelopmental disorder
    • COI: 1:CAS:528:DC%2BD3MXot1Klsr4%3D, PID: 11696674
    • Dunty JWC, Chen SY, Zucker RM, Dehart DB, Sulik KK (2001) Selective vulnerability of embryonic cell populations to ethanol-induced apoptosis: implications for alcohol-related birth defects and neurodevelopmental disorder. Alcohol Clin Exp Res 25:1523–1535
    • (2001) Alcohol Clin Exp Res , vol.25 , pp. 1523-1535
    • Dunty, J.W.C.1    Chen, S.Y.2    Zucker, R.M.3    Dehart, D.B.4    Sulik, K.K.5
  • 34
    • 0027946058 scopus 로고
    • Ethanolinduced oxygen radical formation and lipid peroxidation in rat brain: effect of chronic alcohol consumption
    • COI: 1:CAS:528:DyaK2cXmsVymsL0%3D, PID: 7931342
    • Montoliu C, Valles S, Renau-Piqueras J, Guerri C (1994) Ethanolinduced oxygen radical formation and lipid peroxidation in rat brain: effect of chronic alcohol consumption. J Neurochem 63:1855–1862
    • (1994) J Neurochem , vol.63 , pp. 1855-1862
    • Montoliu, C.1    Valles, S.2    Renau-Piqueras, J.3    Guerri, C.4
  • 35
    • 0028238769 scopus 로고
    • Functions of the neurotrophins during nervous system development: What the knockouts are teaching us
    • PID: 8205613
    • Snider WD (1994) Functions of the neurotrophins during nervous system development: What the knockouts are teaching us. Cell 77:627–738
    • (1994) Cell , vol.77 , pp. 627-738
    • Snider, W.D.1
  • 36
    • 84872168953 scopus 로고    scopus 로고
    • Ascorbic acid modulates monosodium glutamate induced cytotoxicity in rat thymus
    • COI: 1:CAS:528:DC%2BD1MXnvVWmsrg%3D, PID: 19507646
    • Pavlovic V, Pavlovic D, Kocic G, Sokolovic D, Sarac M, Jovic Z (2009) Ascorbic acid modulates monosodium glutamate induced cytotoxicity in rat thymus. Bratislavske´ lekarske listy 110:205–209
    • (2009) Bratislavske´ lekarske listy , vol.110 , pp. 205-209
    • Pavlovic, V.1    Pavlovic, D.2    Kocic, G.3    Sokolovic, D.4    Sarac, M.5    Jovic, Z.6
  • 37
    • 79953895454 scopus 로고    scopus 로고
    • Vitamin C protects against ethanol and PTZ-induced apoptotic neurodegeneration in prenatal rat hippocampal neurons
    • COI: 1:CAS:528:DC%2BC3MXksVKgt7c%3D, PID: 20963815
    • Naseer MI, Ullah N, Ullah I, Koh PO, Lee HY, Park MS, Kim MO (2011) Vitamin C protects against ethanol and PTZ-induced apoptotic neurodegeneration in prenatal rat hippocampal neurons. Synapse 65:562–571
    • (2011) Synapse , vol.65 , pp. 562-571
    • Naseer, M.I.1    Ullah, N.2    Ullah, I.3    Koh, P.O.4    Lee, H.Y.5    Park, M.S.6    Kim, M.O.7
  • 38
    • 0034176843 scopus 로고    scopus 로고
    • Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts
    • COI: 1:CAS:528:DC%2BD3cXhvVOltLk%3D, PID: 10717676
    • Nicholls DG, Ward MW (2000) Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts. Trends Neurosci 23:166–174
    • (2000) Trends Neurosci , vol.23 , pp. 166-174
    • Nicholls, D.G.1    Ward, M.W.2
  • 39
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c
    • COI: 1:CAS:528:DyaK28XktlGnsbY%3D, PID: 8689682
    • Liu X, Kim CN, Yang J, Jemmerson R, Wang X (1996) Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86:147–157
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 41
    • 0034728670 scopus 로고    scopus 로고
    • Amyloid-induced calcium influx induces apoptosis in culture by oxidative stress rather than tau phosphorylation
    • COI: 1:CAS:528:DC%2BD3cXitlOltr8%3D, PID: 10762716
    • Ekinci FJ, Linsley MD, Shea TB (2000) Amyloid-induced calcium influx induces apoptosis in culture by oxidative stress rather than tau phosphorylation. Mol Brain Res 76:389–395
    • (2000) Mol Brain Res , vol.76 , pp. 389-395
    • Ekinci, F.J.1    Linsley, M.D.2    Shea, T.B.3
  • 42
    • 0037097677 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis promotes apoptosis in human neutrophils by activating caspase-3 and altering expression of Bax/Bcl-xL via an oxygen-dependent pathway
    • Perskvist N, Long M, Stendahl O, Zheng L (2000) Mycobacterium tuberculosis promotes apoptosis in human neutrophils by activating caspase-3 and altering expression of Bax/Bcl-xL via an oxygen-dependent pathway. J Immunol 168:6358–6365
    • (2000) J Immunol , vol.168 , pp. 6358-6365
    • Perskvist, N.1    Long, M.2    Stendahl, O.3    Zheng, L.4
  • 43
    • 0034176843 scopus 로고    scopus 로고
    • Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts
    • COI: 1:CAS:528:DC%2BD3cXhvVOltLk%3D, PID: 10717676
    • Nicholls DG, Ward MW (2000) Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts. Trends Neurosci 23:166–174
    • (2000) Trends Neurosci , vol.23 , pp. 166-174
    • Nicholls, D.G.1    Ward, M.W.2
  • 44
    • 0032213768 scopus 로고    scopus 로고
    • AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic beta cells, and may regulate insulin release
    • COI: 1:CAS:528:DyaK1cXnsFeku78%3D, PID: 9794792
    • Salt IP, Johnson G, Ashcroft SJ, Hardie DG (1998) AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic beta cells, and may regulate insulin release. Biochem J 335:533–539
    • (1998) Biochem J , vol.335 , pp. 533-539
    • Salt, I.P.1    Johnson, G.2    Ashcroft, S.J.3    Hardie, D.G.4
  • 45
    • 46749144881 scopus 로고    scopus 로고
    • Activation of AMP-activated protein kinase by tributyltin induces neuronal cell death
    • COI: 1:CAS:528:DC%2BD1cXosVOjsL8%3D, PID: 18511093
    • Nakatsu Y, Kotake Y, Hino A, Ohta S (2008) Activation of AMP-activated protein kinase by tributyltin induces neuronal cell death. Toxicol Appl Pharmacol 230:358–363
    • (2008) Toxicol Appl Pharmacol , vol.230 , pp. 358-363
    • Nakatsu, Y.1    Kotake, Y.2    Hino, A.3    Ohta, S.4
  • 46
    • 34247898927 scopus 로고    scopus 로고
    • Involvement of AMPK signaling cascade in capsaicin-induced apoptosis of HT-29 colon cancer cells
    • COI: 1:CAS:528:DC%2BD2sXks1Gku7g%3D, PID: 17404062
    • Kim YM, Hwang TJ, Kwak DW, Lee YK, Park OJ (2007) Involvement of AMPK signaling cascade in capsaicin-induced apoptosis of HT-29 colon cancer cells. Ann N Y Acad Sci 1095:496–503
    • (2007) Ann N Y Acad Sci , vol.1095 , pp. 496-503
    • Kim, Y.M.1    Hwang, T.J.2    Kwak, D.W.3    Lee, Y.K.4    Park, O.J.5
  • 47
    • 20144368904 scopus 로고    scopus 로고
    • Pharmacological inhibition of AMP-activated protein kinase provides neuroprotection in stroke
    • COI: 1:CAS:528:DC%2BD2MXktlClsro%3D, PID: 15772080
    • McCullough LD, Zeng Z, Li H, Landree LE, McFadden J, Ronnett GV (2005) Pharmacological inhibition of AMP-activated protein kinase provides neuroprotection in stroke. J Biol Chem 280:20493–20502
    • (2005) J Biol Chem , vol.280 , pp. 20493-20502
    • McCullough, L.D.1    Zeng, Z.2    Li, H.3    Landree, L.E.4    McFadden, J.5    Ronnett, G.V.6
  • 48
    • 0021997074 scopus 로고
    • Poly (ADP-ribose) in the cellular response to DNA damage
    • COI: 1:CAS:528:DyaL2MXptFCmuw%3D%3D, PID: 3155867
    • Berger NA (1985) Poly (ADP-ribose) in the cellular response to DNA damage. Radiat Res 101:4–15
    • (1985) Radiat Res , vol.101 , pp. 4-15
    • Berger, N.A.1
  • 49
    • 16244417756 scopus 로고    scopus 로고
    • Regional distribution of fluoro-jade B staining in the hippocampus following traumatic brain injury
    • COI: 1:CAS:528:DC%2BD2MXjtVykurk%3D, PID: 15817271
    • Anderson KJ, Miller KM, Fugaccia I, Scheff SW (2005) Regional distribution of fluoro-jade B staining in the hippocampus following traumatic brain injury. Exp Neurol 193:125–130
    • (2005) Exp Neurol , vol.193 , pp. 125-130
    • Anderson, K.J.1    Miller, K.M.2    Fugaccia, I.3    Scheff, S.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.