Mycobacterium tuberculosis promotes apoptosis in human neutrophils by activating caspase-3 and altering expression of Bax/Bcl-xL via an oxygen-dependent pathway

Journal of Immunology

Volumn 168, Issue 12, 2002, Pages 6358-6365

  Perskvist, Nasrin ^a   Long, Min ^a   Stendahl, Olle ^a   Zheng, Limin ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; DNA FRAGMENT; OXYGEN; PHOSPHATIDYLSERINE; PROTEIN BAX; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BACTERICIDAL ACTIVITY; CELL DEATH; CELL KINETICS; CELL STRUCTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA STRUCTURE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOPATHOLOGY; IMMUNOREGULATION; MACROPHAGE ACTIVATION; MYCOBACTERIUM TUBERCULOSIS; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; OXYGEN TRANSPORT; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM;

EID: 0037097677     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.12.6358     Document Type: Article

References (52)

1. Susceptibility of Beige mice to Mycobacterium avium: Role of neutrophils
2. Chemokine secretion by human polymorphonuclear granulocytes after stimulation with Mycobacterium tuberculosis and lipoarabionmannan
3. The cellular reaction of the pleura to infection with Mycobacterium tuberculosis
4. Lung repair and granuloma formation: Tubercle bacilli stimulated neutrophils release chemotactic factors for monocytes
5. Activation of human neutrophils by Mycobacterium tuberculosis H37Ra involves phospholipase Cγ2. Shc adapter protein, and p38 mitogen-activated protein kinase
6. Phagocytosis and killing of Mycobacterium avium complex by human neutrophils
7. Roles of calcium and annexins in phagocytosis and elimination of an attenuated strain of Mycobacterium tuberculosis in human neutrophils
8. Expression of chemokines and induction of rapid cell death in human blood neutrophils by Mycobacterium tuberculosis
9. The modulation of host cell apoptosis by intracellular bacterial pathogens
10. The induction of apoptosis by bacterial pathogens
11. Macrophage apoptosis in mycobacterial infections
12. Virulent Mycobacterium tuberculosis strains evade apoptosis of infected alveolar macrophages
13. Granulocyte apoptosis and inflammatory diseases
14. Interleukin-10 counterregulates proinflammatory cytokine-induced inhibition of neutrophil apoptosis during severe sepsis
15. Molecular control of neutrophil apoptosis
16. Hypoxia prolongs neutrophil survival in vitro
17. Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: Implications for the regulation of apoptosis in neutrophils
18. Neutrophil undergo apoptosis following ingestion of Escherichia coli
19. Involvement of reactive oxygen intermediates in spontaneous and CD95 (Fas/APO-1)-mediated apoptosis of neutrophils
20. Involvement of caspases in neutrophil apoptosis: Regulation by reactive oxygen species
21. Caspases: Intracellular signaling by proteolysis
22. Caspase structure, proteolytic substrates, and function during apoptotic cell death
23. Caspases mediate tumor necrosis factor-α-induced neutrophil apoptosis and downregulation of reactive oxygen production
24. Caspase-mediated proteolysis and activation of protein kinase Cδ plays a central role in neutrophil apoptosis
25. Cleavage of mitogen-activated protein kinases in human neutrophils undergoing apoptosis: Role in decreased responsiveness to inflammatory cytokines
26. The proto-oncogene Bcl-2 and its role in regulating apoptosis
27. L- and Bax-α-mediated regulation of apoptosis of human neutrophils via caspase-3
28. Cytokine-mediated Bax deficiency and consequent delayed neutrophil apoptosis: A general mechanism to accumulate effector cells in inflammation
29. Mcl-1 expression in human neutrophils: Regulation by cytokine and correlation with cell survival
30. Macrophage phagocytosis of aging neutrophils in inflammation: Programmed cell death in the neutrophil leads to its recognition by macrophages
31. Differential effects of apoptotic versus lysed cells on macrophage production of cytokines: Role of proteases
32. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-β, PGE2, and PAF
33. The effect of the NADPH oxidase inhibitor diphenyleneiodonium on aerobic and anaerobic microbicidal activities of human neutrophils
34. Type I cAMP-dependent protein kinase delays apoptosis in human neutrophils at a site upstream of caspase-3
35. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
36. Immunology of tuberculosis
37. Role of reactive oxygen species (ROS) in apoptosis induction
38. Pivotal role of reactive oxygen species as intracellular mediators of hyperthermia-induced apoptosis
39. Phagocyte receptors for apoptotic cells: Recognition, uptake, and consequences
40. The macrophage haunted by cell ghosts: A pathogen grows
41. Distinct modes of macrophage recognition for apoptotic and necrotic cells are not specified by phospbatidylserine exposure
42. Lipoarabinomannan from Mycobacterium tuberculosis promotes macrophage survival by phosphorylating Bad through a phosphatidylinositol 3-kinase/Akt pathway
43. Reactive oxygen species mediates the mitochondrial-dependent apoptosis induced by transforming growth factor (β) in fetal hepatocytes
44. Effects of staphylococcal enterotoxins on human neutrophil functions and apoptosis
45. Apoptosis of monocytes and prolonged survival of granulocytes as a result of phagocytosis of bacteria
46. Redox regulation of the caspases during apoptosis
47. P53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2
48. Mitochondria damage induced by conditions of oxidative stress
49. Neutrophil-macrophage cooperation in the host defense against mycobacterial infections
50. CD14-dependent clearance of apoptotic cells: Relevance to the immune system
51. Mycobacteria-induced TNF-α and IL-10 formation by human macrophages is differentially regulated at the level of mitogen-activated protein kinase activity
52. Hematopoietic remodeling in interferon-γ-deficient mice infected with mycobacteria