Diacylglycerol Kinase (DGK) Inhibitor II (R59949) Could Suppress Retinal Neovascularization and Protect Retinal Astrocytes in an Oxygen-Induced Retinopathy Model

Journal of Molecular Neuroscience

Volumn 56, Issue 1, 2015, Pages 78-88

  Yang, Lu ^a,b   Xu, Yue ^a   Li, Weihua ^a   Yang, Boyu ^a   Yu, Shanshan ^a   Zhou, Huanjiao ^a   Yang, Cheng ^a,c   Xu, Fan ^a   Wang, Jun ^a   Gao, Yi ^a   Huang, Yongsheng ^a   Lu, Lin ^a   Liang, Xiaoling ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b SHANXI MEDICAL UNIVERSITY   (China)

^c GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

Author keywords

Astrocytes; HIF 1 ; Neovascularization; Oxygen induced retinopathy; PHD 2; R59949; VEGF

Indexed keywords

3 [2 [4 (4,4' DIFLUOROBENZHYDRYLIDENE)PIPERIDINO]ETHYL] 2,3 DIHYDRO 2 THIOXO 4(1H) QUINAZOLINONE; DIACYLGLYCEROL KINASE; EGLN1 PROTEIN, MOUSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR PROLINE DIOXYGENASE; PIPERIDINE DERIVATIVE; QUINAZOLINONE DERIVATIVE; VASCULOTROPIN A;

ANIMAL; ANTAGONISTS AND INHIBITORS; ASTROCYTE; C57BL MOUSE; DRUG EFFECTS; GENETICS; METABOLISM; MOUSE; NEOVASCULARIZATION, PATHOLOGIC; PATHOLOGY; RETINA; RETINA BLOOD VESSEL; RETINOPATHY OF PREMATURITY;

ANIMALS; ASTROCYTES; DIACYLGLYCEROL KINASE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; HYPOXIA-INDUCIBLE FACTOR-PROLINE DIOXYGENASES; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PATHOLOGIC; PIPERIDINES; QUINAZOLINONES; RETINA; RETINAL VESSELS; RETINOPATHY OF PREMATURITY; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84939942947     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-014-0469-2     Document Type: Article

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