Diacylglycerol kinases: Emerging downstream regulators in cell signaling systems

Journal of Biochemistry

Volumn 131, Issue 5, 2002, Pages 629-633

  Kanoh, Hideo ^a   Yamada, Keiko ^a   Sakane, Fumio ^a  

^a SAPPORO MEDICAL UNIVERSITY   (Japan)

Author keywords

Alternative splicing; Diacylglycerol; Diacylglycerol kinase; Phosphatidic acid; Signal transduction

Indexed keywords

DIACYLGLYCEROL; DIACYLGLYCEROL KINASE; ISOENZYME; PHORBOL ESTER; PHOSPHATIDIC ACID; RECEPTOR; REGULATOR PROTEIN; CAENORHABDITIS ELEGANS PROTEIN; DRUG RECEPTOR; PHORBOID RECEPTOR; PROTEIN KINASE C; TYROSINE; UNC 13 PROTEIN, C ELEGANS; UNC-13 PROTEIN, C ELEGANS;

ALTERNATIVE RNA SPLICING; CELL GROWTH; CELL PROLIFERATION; CELL TRANSFORMATION; CYTOLOGY; ENZYME STRUCTURE; GENETICS; HUMAN; INTRACELLULAR TRANSPORT; MAMMAL; MEMBRANE TRANSPORT; NERVOUS SYSTEM FUNCTION; NONHUMAN; PHYSIOLOGY; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SEQUENCE HOMOLOGY; SHORT SURVEY; SIGNAL TRANSDUCTION; ANIMAL; METABOLISM; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; REVIEW;

MAMMALIA;

ALTERNATIVE SPLICING; ANIMALS; CAENORHABDITIS ELEGANS PROTEINS; CONSERVED SEQUENCE; DIACYLGLYCEROL KINASE; DIGLYCERIDES; ISOENZYMES; PHOSPHATIDIC ACIDS; PHOSPHORYLATION; PROTEIN KINASE C; RECEPTORS, DRUG; SIGNAL TRANSDUCTION; TYROSINE;

EID: 0036560847     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a003144     Document Type: Short Survey

References (28)

1. Intracellular signalling by hydrolysis of phospholipids and activation of protein kinase C
2. Mammalian diacylglycerol kinases, a family of lipid kinases with signaling functions
3. Properties and functions of diacylglycerol kinases
4. Diacylglycerol kinase in the central nervous system-molecular heterogeneity and gene expression
5. Molecules in focus: Diacylglycerol kinase
6. Phospholipase D structure and regulation
7. Lipid regulators of membrane traffic through the Golgi complex
8. Phosphatidic acid-mediated mitogenic activation of mTOR signaling
9. Drosophila, retinal degeneration A gene encodes an eye-specific diacylglycerol kinase with cysteine-rich zinc finger motifs and ankyrin repeats
10. Constitutive activity of the light-sensitive channels TRP and TRPL in the Drosophila diacylglycerol kinase mutant, rdgA
11. o decreases the abundance of UNC-13 at release sites
12. qα pathway in C. elegans
13. Role of diacylglycerol kinase α in the attenuation of receptor signaling
14. Src-mediated activation of α-diacylglycerol kinase is required for hepatocyte growth factor-induced cell motility
15. Subtype-specific translocation of diacylglycerol kinase α and γ and its correlation with protein kinase C
16. Diacylglycerol kinase γ is one of the specific receptors of tumor-promoting phorbol esters
17. A domain with homology to neuronal calcium sensors is required for calcium-dependent activation of diacylglycerol kinase α
18. Molecular cloning and characterization of the human diacylglycerol kinase beta (DGKβ) gene: Alternative splicing generates DGKβ isotypes with different properties
19. Selectivity of the diacylglycerol kinase inhibitor 3-2-(4-[bis-(4-fluorophenyl)methylene]-1-piperidinyl) ethyl-2,3-dihydro-2-thioxo-4H(1H)quinazolinone (R59949) among diacylglycerol kinase subtypes
20. Protein kinase C regulates the nuclear localization of diacylglycerol kinase-ζ
21. Interaction of γ1-syntrophin with diacylglycerol kinase-ζ
22. Diacylglycerol kinase ζ regulates Ras activation by a novel mechanism
23. Diacylglycerol kinase ζ in hypothalamus interacts with long form leptin receptor
24. Diacylglycerol kinase ε regulates seizure susceptibility and long-term potentiation through arachidonoyl-inositol lipid signaling
25. Diacylglycerol kinase θ binds to and is negatively regulated by active RhoA
26. Nuclear diacylglycerol kinase-θ is activated in response to α-thrombin
27. Diacylglycerol kinase θ is translocated and phosphoinositide 3-kinase-dependently activated by noradrenaline but not angiotensin II in intact small arteries
28. Diacylglycerol kinase δ suppresses ER-to-Golgi traffic via its SAM and PH domains