The C9orf72 repeat expansion itself is methylated in ALS and FTLD patients

Acta Neuropathologica

Volumn 129, Issue 5, 2015, Pages 715-727

  Xi, Zhengrui ^a   Zhang, Ming ^a   Bruni, Amalia C ^b   Maletta, Raffaele G ^b   Colao, Rosanna ^b   Fratta, Pietro ^c   Polke, James M ^d   Sweeney, Mary G ^d   Mudanohwo, Ese ^d   Nacmias, Benedetta ^e   Sorbi, Sandro ^e   Tartaglia, Maria Carmela ^a,f   Rainero, Innocenzo ^g   Rubino, Elisa ^g   Pinessi, Lorenzo ^g   Galimberti, Daniela ^h   Surace, Ezequiel I ⁱ   McGoldrick, Philip ^a   McKeever, Paul ^a   Moreno, Danielle ^a   Sato, Christine ^a   Liang, Yan ^a   Keith, Julia ^j   Zinman, Lorne ^j   Robertson, Janice ^a   Rogaeva, Ekaterina ^a,f   more..

^a UNIVERSITY OF TORONTO   (Canada)

^b Regional Neurogenetic Center   (Italy)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^e UNIVERSITY OF FLORENCE   (Italy)

^f UNIVERSITY OF TORONTO   (Canada)

^g UNIVERSITY OF TURIN   (Italy)

^h UNIVERSITY OF MILAN   (Italy)

ⁱ Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^j SUNNYBROOK RESEARCH INSTITUTE   (Canada)

more..

Author keywords

ALS; C9orf72; FTLD; G4C2 repeat; Methylation

Indexed keywords

C9ORF72 PROTEIN, HUMAN; PROTEIN; REPETITIVE DNA;

AGED; ALLELE; AMYOTROPHIC LATERAL SCLEROSIS; CPG ISLAND; DNA METHYLATION; DNA SEQUENCE; FEMALE; FRONTOTEMPORAL DEMENTIA; GENETICS; HETEROZYGOTE; HUMAN; MALE; MIDDLE AGED; PROCEDURES; RESTRICTION MAPPING;

AGED; ALLELES; AMYOTROPHIC LATERAL SCLEROSIS; CPG ISLANDS; DNA METHYLATION; DNA REPEAT EXPANSION; FEMALE; FRONTOTEMPORAL LOBAR DEGENERATION; HETEROZYGOTE; HUMANS; MALE; MIDDLE AGED; PROTEINS; RESTRICTION MAPPING; SEQUENCE ANALYSIS, DNA;

EID: 84939941360     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-015-1401-8     Document Type: Article

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