Endoplasmic Reticulum Stress is Involved in the Neuroprotective Effect of Propofol

Neurochemical Research

Volumn 39, Issue 9, 2014, Pages 1741-1752

  Wang, Likui ^a   Tang, Weixiang ^a   Jiang, Tongcui ^a   Lu, Peng ^a   Li, Yuanhai ^a   Sun, Aimin ^a   Shen, Yujun ^a   Chen, Yin ^a   Wang, Haiping ^a   Zong, Zhijun ^a   Wang, Yiqiao ^a   Chen, Lijian ^a   Shen, Yuxian ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

BiP; ER stress; Neuroprotection; Propofol; Unfolded protein response

Indexed keywords

HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78; NEUROPROTECTIVE AGENT; PROPOFOL; TUNICAMYCIN;

CELL LINE; DRUG EFFECTS; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; OXIDATIVE STRESS; UNFOLDED PROTEIN RESPONSE; UPREGULATION;

CELL LINE; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HUMANS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PROPOFOL; TUNICAMYCIN; UNFOLDED PROTEIN RESPONSE; UP-REGULATION;

EID: 84939892139     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-014-1369-0     Document Type: Article

References (38)

1. Sari FR, Watanabe K, Widyantoro B, Thandavarayan RA, Harima M, Zhang S, Muslin AJ, Kodama M, Aizawa Y (2010) Partial inactivation of cardiac 14-3-3 protein in vivo elicits endoplasmic reticulum stress (ERS) and activates ERS-initiated apoptosis in ERS-induced mice. Cell Physiol Biochem 26:167–178
2. Kim I, Xu W, Reed JC (2008) Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. Nat Rev Drug Discov 7:1013–1030
3. Martindale JJ, Fernandez R, Thuerauf D, Whittaker R, Gude N, Sussman MA, Glembotski CC (2006) Endoplasmic reticulum stress gene induction and protection from ischemia/reperfusion injury in the hearts of transgenic mice with a tamoxifen-regulated form of ATF6. Circ Res 98:1186–1193
4. Minamino T, Komuro I, Kitakaze M (2010) Endoplasmic reticulum stress as a therapeutic target in cardiovascular disease. Circ Res 107:1071–1082
5. Wang X, Eno CO, Altman BJ, Zhu Y, Zhao G, Olberding KE, Rathmell JC, Li C (2011) ER stress modulates cellular metabolism. Biochem J 435:285–296
6. Kurisu J, Honma A, Miyajima H, Kondo S, Okumura M, Imaizumi K (2003) MDG1/ERdj4, an ER-resident DnaJ family member, suppresses cell death induced by ER stress. Genes Cells 8:189–202
7. Nakka VP, Gusain A, Raghubir R (2010) Endoplasmic reticulum stress plays critical role in brain damage after cerebral ischemia/reperfusion in rats. Neurotox Res 17:189–202
8. Yamaguchi S, Hamaguchi S, Mishio M, Okuda Y, Kitajima T (2000) Propofol prevents lipid peroxidation following transient forebrain ischemia in gerbils. Can J Anaesth 47:1025–1030
9. Wilson JX, Gelb AW (2002) Free radicals, antioxidants, and neurologic injury: possible relationship to cerebral protection by anesthetics. J Neurosurg Anesthesiol 14:66–79
10. Fu HY, Minamino T, Tsukamoto O, Sawada T, Asai M, Kato H, Asano Y, Fujita M, Takashima S, Hori M, Kitakaze M (2008) Overexpression of endoplasmic reticulum-resident chaperone attenuates cardiomyocyte death induced by proteasome inhibition. Cardiovasc Res 79:600–610
11. Feaver RE, Hastings NE, Pryor A, Blackman BR (2008) GRP78 upregulation by atheroprone shear stress via p38-, alpha2beta1-dependent mechanism in endothelial cells. Arterioscler Thromb Vasc Biol 28:1534–1541
12. Dickhout JG, Hossain GS, Pozza LM, Zhou J, Lhotak S, Austin RC (2005) Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis. Arterioscler Thromb Vasc Biol 25:2623–2629
13. Wu GJ, Chen WF, Hung HC, Jean YH, Sung CS, Chakraborty C, Lee HP, Chen NF, Wen ZH (2011) Effects of propofol on proliferation and anti-apoptosis of neuroblastoma SH-SY5Y cell line: new insights into neuroprotection. Brain Res 1384:42–50
14. Young Y, Menon DK, Tisavipat N, Matta BF, Jones JG (1997) Propofol neuroprotection in a rat model of ischaemia reperfusion injury. Eur J Anaesthesiol 14:320–326
15. Velly LJ, Guillet BA, Masmejean FM, Nieoullon AL, Bruder NJ, Gouin FM, Pisano PM (2003) Neuroprotective effects of propofol in a model of ischemic cortical cell cultures: role of glutamate and its transporters. Anesthesiology 99:368–375
16. Adembri C, Venturi L, Tani A, Chiarugi A, Gramigni E, Cozzi A, Pancani T, De Gaudio RA, Pellegrini-Giampietro DE (2006) Neuroprotective effects of propofol in models of cerebral ischemia: inhibition of mitochondrial swelling as a possible mechanism. Anesthesiology 104:80–89
17. Kobayashi K, Yoshino F, Takahashi SS, Todoki K, Maehata Y, Komatsu T, Yoshida K, Lee MC (2008) Direct assessments of the antioxidant effects of propofol medium chain triglyceride/long chain triglyceride on the brain of stroke-prone spontaneously hypertensive rats using electron spin resonance spectroscopy. Anesthesiology 109:426–435
18. Rossaint J, Rossaint R, Weis J, Fries M, Rex S, Coburn M (2009) Propofol: neuroprotection in an in vitro model of traumatic brain injury. Crit Care 13:R61
19. Hauer D, Ratano P, Morena M, Scaccianoce S, Briegel I, Palmery M, Cuomo V, Roozendaal B, Schelling G, Campolongo P (2011) Propofol enhances memory formation via an interaction with the endocannabinoid system. Anesthesiology 114:1380–1388
20. Murphy PG, Myers DS, Davies MJ, Webster NR, Jones JG (1992) The antioxidant potential of propofol (2,6-diisopropylphenol). Br J Anaesth 68:613–618
21. Hollrigel GS, Toth K, Soltesz I (1996) Neuroprotection by propofol in acute mechanical injury: role of GABAergic inhibition. J Neurophysiol 76:2412–2422
22. Peters CE, Korcok J, Gelb AW, Wilson JX (2001) Anesthetic concentrations of propofol protect against oxidative stress in primary astrocyte cultures: comparison with hypothermia. Anesthesiology 94:313–321
23. Berns M, Seeberg L, Schmidt M, Kerner T (2009) High-dose propofol triggers short-term neuroprotection and long-term neurodegeneration in primary neuronal cultures from rat embryos. J Int Med Res 37:680–688
24. Ouyang YB, Xu LJ, Emery JF, Lee AS, Giffard RG (2011) Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress. Mitochondrion 11:279–286
25. Zhang PL, Lun M, Teng J, Huang J, Blasick TM, Yin L, Herrera GA, Cheung JY (2004) Preinduced molecular chaperones in the endoplasmic reticulum protect cardiomyocytes from lethal injury. Ann Clin Lab Sci 34:449–457
26. Xiao-Hong Y, Li L, Yan-Xia P, Hong L, Wei-Fang R, Yan L, An-Jing R, Chao-Shu T, Wen-Jun Y (2006) Salusins protect neonatal rat cardiomyocytes from serum deprivation-induced cell death through upregulation of GRP78. J Cardiovasc Pharmacol 48:41–46
27. Sato N, Urano F, Yoon Leem J, Kim SH, Li M, Donoviel D, Bernstein A, Lee AS, Ron D, Veselits ML, Sisodia SS, Thinakaran G (2000) Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression. Nat Cell Biol 2:863–870
28. Zhang GG, Teng X, Liu Y, Cai Y, Zhou YB, Duan XH, Song JQ, Shi Y, Tang CS, Yin XH, Qi YF (2009) Inhibition of endoplasm reticulum stress by ghrelin protects against ischemia/reperfusion injury in rat heart. Peptides 30:1109–1116
29. Huang KH, Kuo KL, Chen SC, Weng TI, Chuang YT, Tsai YC, Pu YS, Chiang CK, Liu SH (2012) Down-regulation of glucose-regulated protein (GRP) 78 potentiates cytotoxic effect of celecoxib in human urothelial carcinoma cells. PLoS ONE 7:e33615
30. Yoshida H, Okada T, Haze K, Yanagi H, Yura T, Negishi M, Mori K (2000) ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response. Mol Cell Biol 20:6755–6767
31. Ma Y, Brewer JW, Diehl JA, Hendershot LM (2002) Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response. J Mol Biol 318:1351–1365
32. Bruhat A, Jousse C, Wang XZ, Ron D, Ferrara M, Fafournoux P (1997) Amino acid limitation induces expression of CHOP, a CCAAT/enhancer binding protein-related gene, at both transcriptional and post-transcriptional levels. J Biol Chem 272:17588–17593
33. Oida Y, Shimazawa M, Imaizumi K, Hara H (2008) Involvement of endoplasmic reticulum stress in the neuronal death induced by transient forebrain ischemia in gerbil. Neuroscience 151:111–119
34. Novosyadlyy R, Kurshan N, Lann D, Vijayakumar A, Yakar S, LeRoith D (2008) Insulin-like growth factor-I protects cells from ER stress-induced apoptosis via enhancement of the adaptive capacity of endoplasmic reticulum. Cell Death Differ 15:1304–1317
35. Oyadomari S, Mori M (2004) Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 11:381–389
36. Morimoto N, Oida Y, Shimazawa M, Miura M, Kudo T, Imaizumi K, Hara H (2007) Involvement of endoplasmic reticulum stress after middle cerebral artery occlusion in mice. Neuroscience 147:957–967
37. Wang XZ, Ron D (1996) Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase. Science 272:1347–1349
38. Nakajima A, Tsuji M, Inagaki M, Tamura Y, Kato M, Niiya A, Usui Y, Oguchi K (2014) Neuroprotective effects of propofol on ER stress-mediated apoptosis in neuroblastoma SH-SY5Y cells. Eur J Pharmacol 725:47–54