High-dose propofol triggers short-term neuroprotection and long-term neurodegeneration in primary neuronal cultures from rat embryos

Journal of International Medical Research

Volumn 37, Issue 3, 2009, Pages 680-688

  Berns, Monika ^a   Seeberg, L ^a   Schmidt, M ^a   Kerner, T ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Anaesthetic; Cell viability; Gabazine; Neurodegeneration; Neuroprotection; Picrotoxin; Propofol; aminobutyric acid A receptor

Indexed keywords

3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; PICROTOXIN; PROPOFOL; TETRAZOLIUM; NEUROPROTECTIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG MEGADOSE; EMBRYO; NERVE CELL CULTURE; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; RAT; WISTAR RAT; ANIMAL; ANIMAL EMBRYO; CELL CULTURE; CELL DEATH; CELL PROTECTION; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; NERVE CELL; NEWBORN; PATHOLOGY; TIME;

ANIMALS; ANIMALS, NEWBORN; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, MAMMALIAN; NERVE DEGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; PROPOFOL; RATS; RATS, WISTAR; RECEPTORS, GABA-A; TIME FACTORS;

EID: 70349235520     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323000903700311     Document Type: Article

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