Transforming growth factor-β1 acts via TβR-I on microglia to protect against MPP+-induced dopaminergic neuronal loss

Brain, Behavior, and Immunity

Volumn 51, Issue , 2016, Pages 131-143

  Liu, Zhan ^a   Chen, Hui Qiao ^a   Huang, Yan ^a   Qiu, Yi Hua ^a   Peng, Yu Ping ^a  

^a NANTONG MEDICAL COLLEGE   (China)

Author keywords

DAergic neurons; Microglia; Neuroinflammation; Parkinson's disease; TGF 1; T R I

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CD11B ANTIGEN; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUROTROPHIC FACTOR; NITRIC OXIDE SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SHORT HAIRPIN RNA; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR; TYROSINE 3 MONOOXYGENASE; AUTACOID; PROTEIN SERINE THREONINE KINASE; TGF-BETA TYPE I RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL CULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; DOPAMINERGIC NERVE CELL; ENZYME PHOSPHORYLATION; GENE; GENE SILENCING; IMMUNOCOMPETENT CELL; MICROGLIA; MOUSE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TBETAR I GENE; UPREGULATION; VENTRAL MESENCEPHALON; ANIMAL; ASTROCYTE; BRAIN CORTEX; C57BL MOUSE; DRUG EFFECTS; GENETICS; MESENCEPHALON; METABOLISM; PARKINSONISM;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; ASTROCYTES; CELLS, CULTURED; CEREBRAL CORTEX; DOPAMINERGIC NEURONS; INFLAMMATION MEDIATORS; MAP KINASE SIGNALING SYSTEM; MESENCEPHALON; MICE; MICE, INBRED C57BL; MICROGLIA; PARKINSONIAN DISORDERS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84939864920     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2015.08.006     Document Type: Article

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