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Volumn 58, Issue 2, 1999, Pages 174-187

Expression of transforming growth factor (TGF)-β1, -β2, and -β3 isoforms and TGF-β type I and type II receptors in multiple sclerosis lesions and human adult astrocyte cultures

Author keywords

Cell cultures; Hypertrophic astrocytes; Immunohistochemistry; Macrophages; Microglia; Multiple sclerosis; TGF bioassay

Indexed keywords

MESSENGER RNA; RECEPTOR SUBTYPE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3;

EID: 0033036761     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-199902000-00007     Document Type: Article
Times cited : (112)

References (54)
  • 2
    • 0030225068 scopus 로고    scopus 로고
    • Suppressive effects of TNF-α on myeline formation in vitro
    • Ishikawa M, Tsukamoto T, Yamamoto Suppressive effects of TNF-α on myeline formation in vitro. Acta Neurol Scand 1996;2:91-95
    • (1996) Acta Neurol Scand , vol.2 , pp. 91-95
    • Ishikawa, M.1    Tsukamoto, T.2    Yamamoto3
  • 5
    • 0027845224 scopus 로고
    • Cytokine mRNA expression in inflammatory multiple sclerosis: Detection by non-radioactive in situ hybridization
    • Woodroofe MN, Cuzner ML. Cytokine mRNA expression in inflammatory multiple sclerosis: Detection by non-radioactive in situ hybridization. Cytokine 1993;5:583-88
    • (1993) Cytokine , vol.5 , pp. 583-588
    • Woodroofe, M.N.1    Cuzner, M.L.2
  • 6
    • 0028596581 scopus 로고
    • The impact of microglia-derived cytokines upon gliosis in the CNS
    • Guilian D, Li J. Li X, Georg J, Rutecki PA. The impact of microglia-derived cytokines upon gliosis in the CNS. Dev Neurosci 1994;16:128-36
    • (1994) Dev Neurosci , vol.16 , pp. 128-136
    • Guilian, D.1    Li, J.2    Li, X.3    Georg, J.4    Rutecki, P.A.5
  • 7
    • 0028941871 scopus 로고
    • The adhesion molecule and cytokine profile of multiple sclerosis lesions
    • Cannella B, Raine CS. The adhesion molecule and cytokine profile of multiple sclerosis lesions. Ann Neurol 1995;37:424-35
    • (1995) Ann Neurol , vol.37 , pp. 424-435
    • Cannella, B.1    Raine, C.S.2
  • 8
    • 0030221758 scopus 로고    scopus 로고
    • Cytokines in inflammatory brain lesions: Helpful and harmful
    • Merrill JE, Benveniste EN. Cytokines in inflammatory brain lesions: Helpful and harmful. TINS 1996;19:331-38
    • (1996) TINS , vol.19 , pp. 331-338
    • Merrill, J.E.1    Benveniste, E.N.2
  • 9
    • 0028152937 scopus 로고
    • Transforming growth factor β: The good, the bad, and the ugly
    • Wahl SM. Transforming growth factor β: The good, the bad, and the ugly. J Exp Med 1994;180:1587-90
    • (1994) J Exp Med , vol.180 , pp. 1587-1590
    • Wahl, S.M.1
  • 10
    • 0028903703 scopus 로고
    • Effects of transforming growth factor-beta I on collagen synthesis, integrin expression, adhesion and invasion of glioma cells
    • Paulus W, Baur I, Huettner C, Schmausser B, Roggendorf W, Schlingensiepen KH. Effects of transforming growth factor-beta I on collagen synthesis, integrin expression, adhesion and invasion of glioma cells. J Neuropathol Exp Neurol 1995;54:236-44
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 236-244
    • Paulus, W.1    Baur, I.2    Huettner, C.3    Schmausser, B.4    Roggendorf, W.5    Schlingensiepen, K.H.6
  • 11
    • 0028982242 scopus 로고
    • Transforming growth factor-β1 Null Mice. An animal model for inflammatory disorders
    • Kulkarni AB, Ward JM, Yaswen L, et al. Transforming growth factor-β1 Null Mice. An animal model for inflammatory disorders. Am J Pathol 1995;146:264-75
    • (1995) Am J Pathol , vol.146 , pp. 264-275
    • Kulkarni, A.B.1    Ward, J.M.2    Yaswen, L.3
  • 12
    • 0026541255 scopus 로고
    • Differential expression of transforming growth factor-β1, -β2, and β3 by glioblastoma cells, astrocytes, and microglia
    • Constam DB, Philipp J, Malipiero UV, ten Dijke P, Schachner M, Fontana A. Differential expression of transforming growth factor-β1, -β2, and β3 by glioblastoma cells, astrocytes, and microglia. J Immunol 1992;148:1404-10
    • (1992) J Immunol , vol.148 , pp. 1404-1410
    • Constam, D.B.1    Philipp, J.2    Malipiero, U.V.3    Ten Dijke, P.4    Schachner, M.5    Fontana, A.6
  • 13
    • 0029092637 scopus 로고
    • Regulation of antibody production and class switching by TGF-β
    • Stavnezer J. Regulation of antibody production and class switching by TGF-β. J Immunol 1995;155:1647-51
    • (1995) J Immunol , vol.155 , pp. 1647-1651
    • Stavnezer, J.1
  • 14
    • 0025833740 scopus 로고
    • Isoform specific transforming growth factor-β binding proteins with membrane attachments sensitive to phosphotidylinositol-specific phospholipase C
    • Cheifetz S, Massagué J. Isoform specific transforming growth factor-β binding proteins with membrane attachments sensitive to phosphotidylinositol-specific phospholipase C. J Biol Chem 1991; 266:20767-72
    • (1991) J Biol Chem , vol.266 , pp. 20767-20772
    • Cheifetz, S.1    Massagué, J.2
  • 15
    • 0027332995 scopus 로고
    • Cloning of a TGF beta type I receptor that forms a heterodimeric complex with the TGF beta type II receptor
    • Franzén P, ten Dijke P, Ichijo H, et al. Cloning of a TGF beta type I receptor that forms a heterodimeric complex with the TGF beta type II receptor. Cell 1993;75:681-92
    • (1993) Cell , vol.75 , pp. 681-692
    • Franzén, P.1    Ten Dijke, P.2    Ichijo, H.3
  • 16
    • 0029782780 scopus 로고    scopus 로고
    • Transforming growth factor-β receptors: Role in physiology and disease
    • Kim DH, Kim S-J. Transforming growth factor-β receptors: Role in physiology and disease. J Biomed Sci 1996;3:143-58
    • (1996) J Biomed Sci , vol.3 , pp. 143-158
    • Kim, D.H.1    Kim, S.-J.2
  • 17
    • 0026496172 scopus 로고
    • TGF beta signals through a heterodimeric protein kinase receptor complex
    • Wrana JL, Attisano L, Carcamo J, et al. TGF beta signals through a heterodimeric protein kinase receptor complex. Cell 1992;71: 1003-14
    • (1992) Cell , vol.71 , pp. 1003-1014
    • Wrana, J.L.1    Attisano, L.2    Carcamo, J.3
  • 18
    • 0029114319 scopus 로고
    • Enhanced expression of transforming growth factor-beta and its type-I and type-II receptors in human glioblastoma
    • Yamada N, Kato M, Yamashita H, et al. Enhanced expression of transforming growth factor-beta and its type-I and type-II receptors in human glioblastoma. Int J Cancer 1995;62:386-92
    • (1995) Int J Cancer , vol.62 , pp. 386-392
    • Yamada, N.1    Kato, M.2    Yamashita, H.3
  • 19
    • 0027276765 scopus 로고
    • Beta-glycan presents ligand to the TGF-beta signalling receptor
    • Lopez CF, Wrana JL, Massague J. Beta-glycan presents ligand to the TGF-beta signalling receptor. Cell 1993;73:1435-44
    • (1993) Cell , vol.73 , pp. 1435-1444
    • Lopez, C.F.1    Wrana, J.L.2    Massague, J.3
  • 20
    • 0031013030 scopus 로고    scopus 로고
    • Type I (RI) and Type II (RII) receptors for transforming growth factor-β isoforms are expressed subsequent to transforming growth factor-β ligands during excisional wound repair
    • Gold LI, Sung JJ, Siebert JW, Longaker MT. Type I (RI) and Type II (RII) receptors for transforming growth factor-β isoforms are expressed subsequent to transforming growth factor-β ligands during excisional wound repair. Am J Pathol 1997;150:209-22
    • (1997) Am J Pathol , vol.150 , pp. 209-222
    • Gold, L.I.1    Sung, J.J.2    Siebert, J.W.3    Longaker, M.T.4
  • 21
    • 0023025366 scopus 로고
    • Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix
    • Ignotz RA, Massagué J. Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem 1986;261:4337-45
    • (1986) J Biol Chem , vol.261 , pp. 4337-4345
    • Ignotz, R.A.1    Massagué, J.2
  • 22
    • 0028109801 scopus 로고
    • Transforming growth factor β in tissue fibrosis
    • Border WA, Noble NA. Transforming growth factor β in tissue fibrosis. The New Engl J Med 1994;10:1286-91
    • (1994) The New Engl J Med , vol.10 , pp. 1286-1291
    • Border, W.A.1    Noble, N.A.2
  • 23
    • 0023830701 scopus 로고
    • Antibodies to peptide determinants in transforming growth factor β and their applications
    • Flanders KC, Roberts AB, Ling N, Fleurdelys BE, Sporn MB. Antibodies to peptide determinants in transforming growth factor β and their applications. Biochem 1988;27:739-46
    • (1988) Biochem , vol.27 , pp. 739-746
    • Flanders, K.C.1    Roberts, A.B.2    Ling, N.3    Fleurdelys, B.E.4    Sporn, M.B.5
  • 24
    • 0024593615 scopus 로고
    • Transforming growth factor-β1: Histochemical localization with antibodies to different epitopes
    • Flanders KC, Thompson NL, Cissel DS, et al. Transforming growth factor-β1: Histochemical localization with antibodies to different epitopes. J Cell Biol 1989;108:653-60
    • (1989) J Cell Biol , vol.108 , pp. 653-660
    • Flanders, K.C.1    Thompson, N.L.2    Cissel, D.S.3
  • 25
  • 26
    • 0024559439 scopus 로고
    • KP1: A new monoclonal antibody that detects a monocyte/macrophage associated antigen in routinely processed tissue sections
    • Pulford KA, Rigney EM, Micklem KJ, et al. KP1: A new monoclonal antibody that detects a monocyte/macrophage associated antigen in routinely processed tissue sections. J Clin Pathol 1989;42: 414-21
    • (1989) J Clin Pathol , vol.42 , pp. 414-421
    • Pulford, K.A.1    Rigney, E.M.2    Micklem, K.J.3
  • 27
    • 0021989441 scopus 로고
    • A monoclonal antibody to a differentiation antigen present on mature human macrophages and absent from monocytes
    • Zwadlo G, Bröckner EB, Bassewitz BD, Feige U, Sorg C. A monoclonal antibody to a differentiation antigen present on mature human macrophages and absent from monocytes. J. Immunol 1985; 134:1487-92
    • (1985) J. Immunol , vol.134 , pp. 1487-1492
    • Zwadlo, G.1    Bröckner, E.B.2    Bassewitz, B.D.3    Feige, U.4    Sorg, C.5
  • 28
    • 0030841387 scopus 로고    scopus 로고
    • Establishment of human adult astrocyte cultures derived from postmortem multiple sclerosis and control brain and spinal cord regions: Immunophenotypical and functional characterization
    • De Groot CJA, Langeveld CH, Jongenelen CAM, Montagne L, Van der Valk P, Dijkstra CD. Establishment of human adult astrocyte cultures derived from postmortem multiple sclerosis and control brain and spinal cord regions: Immunophenotypical and functional characterization. J Neurosci Res 1997;49:342-54
    • (1997) J Neurosci Res , vol.49 , pp. 342-354
    • De Groot, C.J.A.1    Langeveld, C.H.2    Jongenelen, C.A.M.3    Montagne, L.4    Van Der Valk, P.5    Dijkstra, C.D.6
  • 29
    • 0030636128 scopus 로고    scopus 로고
    • Immunocytochemical characterization of the expression of inducible and constitutive isoforms of nitric oxide synthase in demyelinating multiple sclerosis lesions
    • De Groot CJA, Ruuls SR, Theeuwes JWM, Dijkstra CD, Van Der Valk P. Immunocytochemical characterization of the expression of inducible and constitutive isoforms of nitric oxide synthase in demyelinating multiple sclerosis lesions. J Neuropathol Exp Neurol 1997;56:10-20
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 10-20
    • De Groot, C.J.A.1    Ruuls, S.R.2    Theeuwes, J.W.M.3    Dijkstra, C.D.4    Van Der Valk, P.5
  • 30
    • 0024448523 scopus 로고
    • Isolation and characterization of brain macrophages from the central nervous system of newborn and adult rats and of rats with experimental allergic encephalomyelitis
    • De Groot CJA, Sminia T, Dijkstra CD. Isolation and characterization of brain macrophages from the central nervous system of newborn and adult rats and of rats with experimental allergic encephalomyelitis. Immunobiol 1989;179:314-27
    • (1989) Immunobiol , vol.179 , pp. 314-327
    • De Groot, C.J.A.1    Sminia, T.2    Dijkstra, C.D.3
  • 31
    • 0029031527 scopus 로고
    • Postmortem delay effects on neuroglial cells and brain macrophages from Lewis rats with acute experimental allergic encephalomyelitis: An immunohistochemical and cytochemical study
    • De Groot CJA, Theeuwes JWM, Dijkstra CD, Van Der Valk P. Postmortem delay effects on neuroglial cells and brain macrophages from Lewis rats with acute experimental allergic encephalomyelitis: An immunohistochemical and cytochemical study. J Neuroimmunol 1995;59:123-34
    • (1995) J Neuroimmunol , vol.59 , pp. 123-134
    • De Groot, C.J.A.1    Theeuwes, J.W.M.2    Dijkstra, C.D.3    Van Der Valk, P.4
  • 32
    • 0028328817 scopus 로고
    • An assay for transforming growth factor-β using cells transfected with a plaminogen activator inhibitor-1 promotor-luciferase construct
    • Abe M, Harpel JG, Metz CN, Nunes I, Loskutoff DJ, Rifkin DB. An assay for transforming growth factor-β using cells transfected with a plaminogen activator inhibitor-1 promotor-luciferase construct. Anal Biochem 1994;216:276-84
    • (1994) Anal Biochem , vol.216 , pp. 276-284
    • Abe, M.1    Harpel, J.G.2    Metz, C.N.3    Nunes, I.4    Loskutoff, D.J.5    Rifkin, D.B.6
  • 33
    • 0031553962 scopus 로고    scopus 로고
    • Quantification of transforming growth factor-β in biological material using cells transfected with plasminogen activator inhibitor-1 promoter-luciferase construct
    • Van Waarde MAWH, Van Assen AJ, Kampinga HH, Konings ATW, Vujaskovic Z. Quantification of transforming growth factor-β in biological material using cells transfected with plasminogen activator inhibitor-1 promoter-luciferase construct. Anal Biochem 1997;247:45-51
    • (1997) Anal Biochem , vol.247 , pp. 45-51
    • Van Waarde, M.A.W.H.1    Van Assen, A.J.2    Kampinga, H.H.3    Konings, A.T.W.4    Vujaskovic, Z.5
  • 35
    • 0025915948 scopus 로고
    • Cytokine production by the bladder carcinoma cell line 5637: Rapid analysis of mRNA expression level, using a cDNA-PCR procedure
    • Kaashoek JGJ, Mout R, Falkenburg JHF, Willemze R, Fibbe WE, Landegent JF. Cytokine production by the bladder carcinoma cell line 5637: Rapid analysis of mRNA expression level, using a cDNA-PCR procedure. Lymphokine Cytokine Res 1991;10:231-35
    • (1991) Lymphokine Cytokine Res , vol.10 , pp. 231-235
    • Kaashoek, J.G.J.1    Mout, R.2    Falkenburg, J.H.F.3    Willemze, R.4    Fibbe, W.E.5    Landegent, J.F.6
  • 36
    • 0028859484 scopus 로고
    • Decreased type-II, type-I TGF-beta receptor ratio in cells derived from human atherosclerotic lesion-conversion from an anti-proliferative to pro-fibrotic response to TGF-beta-1
    • McCaffrey TA, Consigli S, Du BH, et al. Decreased type-II, type-I TGF-beta receptor ratio in cells derived from human atherosclerotic lesion-conversion from an anti-proliferative to pro-fibrotic response to TGF-beta-1. J Clin Invest 1995;96:2667-75
    • (1995) J Clin Invest , vol.96 , pp. 2667-2675
    • McCaffrey, T.A.1    Consigli, S.2    Du, B.H.3
  • 37
    • 0023478466 scopus 로고
    • cDNA cloning of the human U1 snRNA-associated A protein: Extensive homology between U1 and U2 snRNA-specific proteins
    • Sillekens PTG, Habets WJ, Beijer RP, Venrooij WJ. cDNA cloning of the human U1 snRNA-associated A protein: Extensive homology between U1 and U2 snRNA-specific proteins. EMBO J 1987;6: 3841-48
    • (1987) EMBO J , vol.6 , pp. 3841-3848
    • Sillekens, P.T.G.1    Habets, W.J.2    Beijer, R.P.3    Venrooij, W.J.4
  • 38
    • 0030806651 scopus 로고    scopus 로고
    • Enhanced expression of MMP-7 and MMP-9 in demyelinating multiple sclerosis lesions
    • Cossins JA, Clements JM, Ford J, Miller MM, et al. Enhanced expression of MMP-7 and MMP-9 in demyelinating multiple sclerosis lesions. Acta Neuropathol 1997;94:590-98
    • (1997) Acta Neuropathol , vol.94 , pp. 590-598
    • Cossins, J.A.1    Clements, J.M.2    Ford, J.3    Miller, M.M.4
  • 39
    • 0142026496 scopus 로고    scopus 로고
    • Glial transforming growth factor (TGF)-β isotypes in multiple sclerosis: Differential glial expression of TGF-β1.2 and 3 isotypes in multiple sclerosis
    • Peress NS, Perillo E, Seidman RJ. Glial transforming growth factor (TGF)-β isotypes in multiple sclerosis: Differential glial expression of TGF-β1.2 and 3 isotypes in multiple sclerosis. J Neuroimmunol 1996;71:115-23
    • (1996) J Neuroimmunol , vol.71 , pp. 115-123
    • Peress, N.S.1    Perillo, E.2    Seidman, R.J.3
  • 40
    • 0032005876 scopus 로고    scopus 로고
    • Regulation of Astrocyte GFAP Expression by TGF-β1 and FGF-2
    • Reilly JF, Maher PA, Kumari VG. Regulation of Astrocyte GFAP Expression by TGF-β1 and FGF-2. Glia 1998;22:202-10
    • (1998) Glia , vol.22 , pp. 202-210
    • Reilly, J.F.1    Maher, P.A.2    Kumari, V.G.3
  • 41
    • 0025972447 scopus 로고
    • Immunocytochemical study of macrophages and microglia cells and extracellular matrix components in human CNS disease: 2. Non-neoplastic diseases
    • Esiri MM, Morris CS. Immunocytochemical study of macrophages and microglia cells and extracellular matrix components in human CNS disease: 2. Non-neoplastic diseases. J Neurol Sci 1991;101: 59-72
    • (1991) J Neurol Sci , vol.101 , pp. 59-72
    • Esiri, M.M.1    Morris, C.S.2
  • 42
    • 0024450306 scopus 로고
    • Fibronectin in multiple sclerosis
    • Sobel RA, Mitchell ME. Fibronectin in multiple sclerosis. Am J Pathol 1989;135:161-68
    • (1989) Am J Pathol , vol.135 , pp. 161-168
    • Sobel, R.A.1    Mitchell, M.E.2
  • 43
    • 0030726363 scopus 로고    scopus 로고
    • Extracellular matrix proteins expressed by human adult astrocytes in vivo and in vitro: An astrocyte surface protein containing the CS1 domain contributes to binding of lymphoblasts
    • Van der Laan LJW, De Groot CJA. Elices MJ, Dijkstra CD. Extracellular matrix proteins expressed by human adult astrocytes in vivo and in vitro: An astrocyte surface protein containing the CS1 domain contributes to binding of lymphoblasts. J Neurosci Res 1997; 50:539-48
    • (1997) J Neurosci Res , vol.50 , pp. 539-548
    • Van Der Laan, L.J.W.1    De Groot, C.J.A.2    Elices, M.J.3    Dijkstra, C.D.4
  • 44
    • 0031106002 scopus 로고    scopus 로고
    • Inhibition of endotoxin-induced nitric oxide synthase production in microglial cells by the presence of astroglial cells: A role for transforming growth factor β
    • Vincent VAM, Tilders FJH, Van Dam A-M. Inhibition of endotoxin-induced nitric oxide synthase production in microglial cells by the presence of astroglial cells: A role for transforming growth factor β. Glia 1997;19:190-98
    • (1997) Glia , vol.19 , pp. 190-198
    • Vincent, V.A.M.1    Tilders, F.J.H.2    Van Dam, A.-M.3
  • 45
    • 0030004008 scopus 로고
    • Distribution of transforming growth factor-β isoforms in human immunodeficiency virus-1 encephalitis
    • Johnson MD, Gold LI. Distribution of transforming growth factor-β isoforms in human immunodeficiency virus-1 encephalitis. Human Pathol 1995;27:643-49
    • (1995) Human Pathol , vol.27 , pp. 643-649
    • Johnson, M.D.1    Gold, L.I.2
  • 46
    • 0025775004 scopus 로고
    • Macrophage and astrocyte-derived transforming growth factor-β as a mediator of central nervous system dysfunction in acquired immune deficiency syndrome
    • Wahl SM, Allen JB, McCartney-Francis N, Morganti-Kossmann MC, et al. Macrophage and astrocyte-derived transforming growth factor-β as a mediator of central nervous system dysfunction in acquired immune deficiency syndrome. J Exp Med 1991;173:981-91
    • (1991) J Exp Med , vol.173 , pp. 981-991
    • Wahl, S.M.1    Allen, J.B.2    McCartney-Francis, N.3    Morganti-Kossmann, M.C.4
  • 47
    • 0029046504 scopus 로고
    • Altered expression of transforming growth factor-β in Alzheimer's disease
    • Flanders KC, Lippa CF, Smith TW, Pollen DA, Sporn MB. Altered expression of transforming growth factor-β in Alzheimer's disease. Neurol. 1995;45:1561-69
    • (1995) Neurol. , vol.45 , pp. 1561-1569
    • Flanders, K.C.1    Lippa, C.F.2    Smith, T.W.3    Pollen, D.A.4    Sporn, M.B.5
  • 48
    • 0028973319 scopus 로고
    • Differential expression of TGF-β1, 2 and 3 isotypes in Alzheimer's disease: A comparative immunohistochemical study with cerebral infarction, aged human and mouse control brains
    • Peress NS, Perillo E. Differential expression of TGF-β1, 2 and 3 isotypes in Alzheimer's disease: A comparative immunohistochemical study with cerebral infarction, aged human and mouse control brains. J Neuropathol Exp Neurol 1995;54:802-11
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 802-811
    • Peress, N.S.1    Perillo, E.2
  • 49
    • 0027953227 scopus 로고
    • Organ-specific autoantigens induce transforming growth factor-β mRNA expression in mononuclear cells in multiple sclerosis and myasthenia gravis
    • Link J, Fredrikson S, Soderstrom M, et al. Organ-specific autoantigens induce transforming growth factor-β mRNA expression in mononuclear cells in multiple sclerosis and myasthenia gravis. Ann Neurol 1994;35:197-203
    • (1994) Ann Neurol , vol.35 , pp. 197-203
    • Link, J.1    Fredrikson, S.2    Soderstrom, M.3
  • 50
    • 0028095562 scopus 로고
    • Increased transforming growth factor-β, interleukin-4 and interferon-γ in multiple sclerosis
    • Link J, Söderström M, Olsson T, Höjeberg B, Ljungdahl Å, Link H. Increased transforming growth factor-β, interleukin-4 and interferon-γ in multiple sclerosis. Ann Neurol 1994;36:379-86
    • (1994) Ann Neurol , vol.36 , pp. 379-386
    • Link, J.1    Söderström, M.2    Olsson, T.3    Höjeberg, B.4    Å, L.5    Link, H.6
  • 51
    • 0027161216 scopus 로고
    • Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide
    • Merrill JE, Ignarro LJ, Sherman MP, Melinek J, Lane TE. Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J Immunol 1993;151:2132-41
    • (1993) J Immunol , vol.151 , pp. 2132-2141
    • Merrill, J.E.1    Ignarro, L.J.2    Sherman, M.P.3    Melinek, J.4    Lane, T.E.5
  • 52
    • 0028967734 scopus 로고
    • Tumor necrosis factor-α and transforming growth factor-β upregulate astrocyte expression of MCP-1
    • Hurwitz AA, Lyman WD, Berman JW. Tumor necrosis factor-α and transforming growth factor-β upregulate astrocyte expression of MCP-1. J Neuroimmunol 1985;57:193-98
    • (1985) J Neuroimmunol , vol.57 , pp. 193-198
    • Hurwitz, A.A.1    Lyman, W.D.2    Berman, J.W.3
  • 53
    • 0029077755 scopus 로고
    • Increased central nervous system production of extracellular matrix components and development of hydrocephalus in transgenic mice overexpressing transforming growth factor-β1
    • Wyss-Coray T, Feng L, Masliah E, et al. Increased central nervous system production of extracellular matrix components and development of hydrocephalus in transgenic mice overexpressing transforming growth factor-β1. Am J Pathol 1995;147:53-67
    • (1995) Am J Pathol , vol.147 , pp. 53-67
    • Wyss-Coray, T.1    Feng, L.2    Masliah, E.3
  • 54
    • 0030905019 scopus 로고    scopus 로고
    • Expression of various TGF-β isoforms and type I receptor in necrotizing human brain lesions
    • Ata AK, Funa K, Olsson Y. Expression of various TGF-β isoforms and type I receptor in necrotizing human brain lesions. Acta Neuropathol 1997;93:326-33
    • (1997) Acta Neuropathol , vol.93 , pp. 326-333
    • Ata, A.K.1    Funa, K.2    Olsson, Y.3


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